The impact of NAT2 acetylator genotype on mutagenesis and DNA adducts from 2-amino-9H-pyrido[2,3-b]indole

Chemical Research in Toxicology

Volumn 22, Issue 4, 2009, Pages 726-733

  Turesky, Robert J ^a   Bendaly, Jean ^b   Yasa, Isil ^a   Doll, Mark A ^b   Hein, David W ^b  

^a WADSWORTH CENTER   (United States)

^b University of Louisville School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO ALPHA CARBOLINE; 2 HYDROXYAMINO 9H PYRIDO[2,3 B]INDOLE; AMINE; ARYLAMINE ACETYLTRANSFERASE; CYTOCHROME P450 1A2; DEOXYGUANOSINE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; INDOLE DERIVATIVE; N(DEOXYGUANOSIN 8 YL) 2 AMINO 9H PYRIDO[2,3 B]INDOLE; NAT2 ENZYME; TOBACCO SMOKE; UNCLASSIFIED DRUG;

ALLELE; ANIMAL CELL; ARTICLE; CHEMICAL BINDING; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA ADDUCT; EXCISION REPAIR; GENE MUTATION; GENETIC POLYMORPHISM; GENOTOXICITY; GENOTYPE; MASS SPECTROMETRY; MUTAGENESIS; NONHUMAN; OXIDATION; PHENOTYPE; WILD TYPE;

ANIMALS; ARYLAMINE N-ACETYLTRANSFERASE; CARBOLINES; CELL LINE; CHO CELLS; CHROMATOGRAPHY, LIQUID; CRICETINAE; CRICETULUS; CYTOCHROME P-450 ENZYME SYSTEM; DNA ADDUCTS; GENOTYPE; HUMANS; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTAGENESIS; PHENOTYPE; POLYMORPHISM, GENETIC; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TRANSFECTION;

CRICETULUS GRISEUS; NICOTIANA TABACUM;

EID: 66049089218     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx800473w     Document Type: Article

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