Specific site methylation in the 5′-flanking region of CYP1A2: Interindividual differences in human livers

Life Sciences

Volumn 69, Issue 7, 2001, Pages 839-845

  Hammons, George J ^a,b   Yan Sanders, Yan ^a   Jin, Bo ^a   Blann, Ernice ^a   Kadlubar, Fred F ^a   Lyn Cook, Beverly D ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b Division of Molecular Epidemiology   (United States)

Author keywords

CpG methylation; CYP1A2; Epigenetic regulation; Hypermethylation

Indexed keywords

CYTOCHROME P450 1A2; DNA; PROMUTAGEN;

5' UNTRANSLATED REGION; ANALYTIC METHOD; ARTICLE; BINDING SITE; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; INDIVIDUALITY; LIVER; MAJOR CLINICAL STUDY; METABOLIC ACTIVATION; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; REGULATORY MECHANISM;

CYTOCHROME P-450 CYP1A2; DNA; DNA METHYLATION; DNA PRIMERS; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LIVER; POINT MUTATION; POLYMORPHISM, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA;

EID: 0035816343     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0024-3205(01)01175-4     Document Type: Article

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