Metabolism of 2-amino-α-carboline: A food-borne heterocyclic amine mutagen and carcinogen by human and rodent liver microsomes and by human cytochrome P4501A2

Drug Metabolism and Disposition

Volumn 24, Issue 4, 1996, Pages 395-400

  Raza, Haider ^a,c   King, Roberta S ^a,b   Burke Squires, R ^a   Guengerich, F Peter ^a   Miller, Dwight W ^a   Freeman, J Patrick ^a   Lang, Nicholas P ^b   Kadlubar, Fred F ^a,d  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b John L McClellan Memorial Veterans   (United States)

^c UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^d NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 AMINO ALPHA CARBOLINE; 4 BIPHENYLAMINE; ALPHA NAPHTHOFLAVONE; CARBOLINE DERIVATIVE; CYTOCHROME P450 ISOENZYME; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CARCINOGENICITY; CATALYSIS; FLUORESCENCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; HYDROXYLATION; LIVER MICROSOME METABOLISM; MALE; MASS SPECTROMETRY; METABOLITE; MOUSE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; ULTRAVIOLET RADIATION;

ANIMALS; BLOTTING, WESTERN; CARBOLINES; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 CYP1A2; CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; IMMUNOBLOTTING; MALE; MICE; MICE, INBRED SENCAR; MICROSOMES, LIVER; MUTAGENS; OXIDOREDUCTASES; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS;

EID: 0029935767     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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