Natural product inhibitors of protein-protein interactions mediated by Src-family SH2 domains

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 12, 2009, Pages 3305-3309

  Sperl, Bianca ^a   Seifert, Markus H J ^b   Berg, Thorsten ^a  

^a MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^b 4SC AG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CAFTARIC ACID; NATURAL PRODUCT; PROTEIN KINASE LCK; PROTEIN SH2; PROTEIN TYROSINE KINASE; ROSMARINIC ACID; SALVIANOLIC ACID A; SALVIANOLIC ACID B; STAT1 PROTEIN; STAT3 PROTEIN; STAT5B PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG POTENCY; HYDROGEN BOND; HYDROPHILICITY; HYDROPHOBICITY; IC 50; LIGAND BINDING; MOLECULAR MODEL; PROTEIN DOMAIN; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; STRUCTURE ACTIVITY RELATION;

BENZOFURANS; BIOLOGICAL PRODUCTS; CAFFEIC ACIDS; DRUG DISCOVERY; HUMANS; LACTATES; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MODELS, MOLECULAR; PHENOLS; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS PP60(C-SRC); SRC HOMOLOGY DOMAINS; SRC-FAMILY KINASES;

EID: 65749095573     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.04.083     Document Type: Article

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