Asterriquinones produced by Aspergillus candidus inhibit binding of the Grb-2 adapter to phosphorylated EGF receptor tyrosine kinase

Journal of Antibiotics

Volumn 52, Issue 3, 1999, Pages 215-223

  Alvi, Khisal A ^a   Pu, Henry ^a   Luche, Michele ^b   Rice, Audie ^b   App, Harald ^b   McMahon, Gerald ^b   Dare, Heidi ^c   Margolis, Ben ^c  

^a MDS Inc   (Canada)

^b SUGEN INC   (United States)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASTERRIQUINONE DERIVATIVE; EPIDERMAL GROWTH FACTOR RECEPTOR; GRB 2 ADAPTER; GRB 7; PLC GAMMA; PROTEIN; PROTEIN INHIBITOR; PROTEIN TYROSINE KINASE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS; CONTROLLED STUDY; DEUTERON NUCLEAR MAGNETIC RESONANCE; DRUG ISOLATION; DRUG POTENCY; DRUG PURIFICATION; DRUG SPECIFICITY; DRUG STRUCTURE; FERMENTATION; MASS SPECTROMETRY; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION;

ASPERGILLUS CANDIDUS;

EID: 0032902774     PISSN: 00218820     EISSN: None     Source Type: Journal    
DOI: 10.7164/antibiotics.52.215     Document Type: Article

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