메뉴 건너뛰기




Volumn 53, Issue 4, 2009, Pages 1516-1527

New high-throughput screening assay to reveal similarities and differences in inhibitory sensitivities of multidrug ATP-binding cassette transporters

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTIFUNGAL AGENT; CDR1P PROTEIN; FLUPHENAZINE; KETOCONAZOLE; M 961; PDR5P PROTEIN; PHENOTHIAZINE; RHODAMINE 6G; SNQ2P PROTEIN; UNCLASSIFIED DRUG;

EID: 65649120780     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00956-08     Document Type: Article
Times cited : (22)

References (62)
  • 1
    • 0028082188 scopus 로고
    • PDR5, a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDR1
    • Balzi, E., M. Wang, S. Leterme, L. Van Dyck, and A. Goffeau. 1994. PDR5. a novel yeast multidrug resistance conferring transporter controlled by the transcription regulator PDRl. J. Biol. Chem. 269:2206-2214. (Pubitemid 24035434)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.3 , pp. 2206-2214
    • Balzi, E.1    Wang, M.2    Leterme, S.3    Van Dyck, L.4    Goffeau, A.5
  • 2
    • 0021668558 scopus 로고
    • A positive selection for mutants lacking orotidine-5 '-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance
    • Boeke, J. D., F. LaCroute, and G. R. Fink. 1984. A positive selection for mutants lacking orotidine-5 '-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance. MoI. Gen. Genet. 197:345-346.
    • (1984) MoI. Gen. Genet , vol.197 , pp. 345-346
    • Boeke, J.D.1    LaCroute, F.2    Fink, G.R.3
  • 3
    • 0030795841 scopus 로고    scopus 로고
    • Characterization of functional assays of multidrug resistance P-glycoprotein transport activity
    • Bosch, L, C. L. Crankshaw, D. Piwnica-Worms, and J. M. Croop. 1997. Characterization of functional assays of multidrug resistance P-glycoprotein transport activity. Leukemia 11:1131-1137. (Pubitemid 27345967)
    • (1997) Leukemia , vol.11 , Issue.7 , pp. 1131-1137
    • Bosch, I.1    Crankshaw, C.L.2    Piwnica-Worms, D.3    Croop, J.M.4
  • 4
    • 0028904919 scopus 로고
    • Characterization of uptake and hydrolysis of fluorescein diacetate and arboxyfluorescein diacetate by intracellular ester-ases in Saccharomyces cerevisiae, which result in accumulation of fluorescent product
    • Breeuwer, P., J. L. Drocourt, N. Bunschoten, M. H. Zwietering, F. M. Rom-bouts, and T. Abee. 1995. Characterization of uptake and hydrolysis of fluorescein diacetate and carboxyfluorescein diacetate by intracellular ester-ases in Saccharomyces cerevisiae, which result in accumulation of fluorescent product. Appl. Environ. Microbiol. 61:1614-1619.
    • (1995) Appl. Environ. Microbiol. , vol.61 , pp. 1614-1619
    • Breeuwer, P.1    Drocourt, J.L.2    Bunschoten, N.3    Zwietering, M.H.4    Rombouts F., M.5    Abee, T.6
  • 5
    • 0034643830 scopus 로고    scopus 로고
    • Prenyl-flavonoids as potent inhibitors of the Pdr5p multidrug ABC transporter from Saccharomyces cerevisiae
    • DOI 10.1021/bi000040f
    • Conseil, G., A. Decottignies, J. M. Jault, G. Comte, D. Barron, A. Goffeau, and A. Di Pietro. 2000. Frenyl-flavonoids as potent inhibitors of the Fdr5p multidrug ABC transporter from Saccharomyces cerevisiae. Biochemistry 39: 6910-6917. (Pubitemid 30390384)
    • (2000) Biochemistry , vol.39 , Issue.23 , pp. 6910-6917
    • Conseil, G.1    Decottignies, A.2    Jault, J.-M.3    Comte, G.4    Barron, D.5    Goffeau, A.6    Di Pietro, A.7
  • 6
    • 0029073576 scopus 로고
    • Identification and character-ization of SNQ2, a new multidrug ATP binding cassette transporter of the yeast plasma membrane
    • Decottignies, A., L. Lambert, P. Catty, H. Degand, E. A. Epping, W. S. Move-Rowley, E. Balzi, and A. Goffeau. 1995. Identification and character-ization of SNQ2, a new multidrug ATP binding cassette transporter of the yeast plasma membrane. J. Biol. Chem. 270:18150-18157.
    • (1995) J. Biol. Chem. , vol.270 , pp. 18150-18157
    • Decottignies, A.1    Lambert, L.2    Catty, P.3    Degand, H.4    Epping, E.A.5    Move-Rowley S, W.6    Balzi, E.7    Goffeau, A.8
  • 7
    • 0028352302 scopus 로고
    • Solubilization and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast
    • Decottignies, A., M. Kolaczkowski, E. Balzi, and A. Goffeau. 1994. Solubili-zation and characterization of the overexpressed PDR5 multidrug resistance nucleotide triphosphatase of yeast. J. Biol. Chem. 269:12797-12803. (Pubitemid 24202075)
    • (1994) Journal of Biological Chemistry , vol.269 , Issue.17 , pp. 12797-12803
    • Decottignies, A.1    Kolaczkowski, M.2    Balzi, E.3    Goffeau, A.4
  • 8
    • 0027998450 scopus 로고
    • PDR3, a new yeast regulatory gene, is homologous to PDR1 and controls the multidrug resistance phenomenon
    • Delaveau, T., A. Delahodde, E. Carvajal, J. Subik, and C. Jacq. 1994. PDR3, a new yeast regulatory gene, is homologous to PDRl and controls the multidrug resistance phenomenon. MoI. Gen. Genet. 244:501-511. (Pubitemid 24281464)
    • (1994) Molecular and General Genetics , vol.244 , Issue.5 , pp. 501-511
    • Delaveau, T.1    Delahodde, A.2    Carvajal, E.3    Subik, J.4    Jacq, C.5
  • 9
    • 0033580634 scopus 로고    scopus 로고
    • A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol
    • Dey, S., P. Hafkemeyer, I. Pastan, and M. M. Gottesman. 1999. A single amino acid residue contributes to distinct mechanisms of inhibition of the human multidrug transporter by stereoisomers of the dopamine receptor antagonist flupentixol. Biochemistry 38:6630-6639. (Pubitemid 129514962)
    • (1999) Biochemistry , vol.38 , Issue.20 , pp. 6630-6639
    • Dey, S.1    Hafkemeyer, P.2    Pastan, I.3    Gottesman, M.M.4
  • 10
    • 0024201181 scopus 로고
    • Plasma membrane ATPase from the yeast Schizosaccharomycespombe
    • Dufour, J. P., A. Amory, and A. Goffeau. 1988. Plasma membrane ATPase from the yeast Schizosaccharomycespombe. Methods Enzymol. 157:513-528.
    • (1988) Methods Enzymol. , vol.157 , pp. 513-528
    • Dufour, J.P.1    Amory, A.2    Goffeau, A.3
  • 11
    • 0002515716 scopus 로고
    • V Lorian (ed.), Antibiotics in laboratory medicine, 3rd ed. The Williams and Wilkins Co., Baltimore, MD.
    • Eliopoulos, G. M., and R. C. Moellering. 1991. Antimicrobial combinations, p. 432-492. In V. Lorian (ed.), Antibiotics in laboratory medicine, 3rd ed. The Williams and Wilkins Co., Baltimore, MD.
    • (1991) Antimicrobial combinations , pp. 432-492
    • Eliopoulos, G.M.1    Moellering, R.C.2
  • 12
    • 0034176255 scopus 로고    scopus 로고
    • Use of chemical chaperones in the yeast Saccharomyces cerevisiae to enhance heterologous membrane protein expression: High-yield expression and purification of human P-glycoprotein
    • DOI 10.1006/abbi.2000.1712
    • Figler, R. A., H. Omote, R. K. Nakamoto, and M. K. Al-Shawi. 2000. Use of chemical chaperones in the yeast Saccharomyces cerevisiae to enhance heterologous membrane protein expression: high-yield expression and puri-fication of human P-glycoprotein. Arch. Biochem. Biophys. 376:34-46. (Pubitemid 30205112)
    • (2000) Archives of Biochemistry and Biophysics , vol.376 , Issue.1 , pp. 34-46
    • Figler, R.A.1    Omote, H.2    Nakamoto, R.K.3    Al-Shawi, M.K.4
  • 13
    • 0025007511 scopus 로고
    • Pharmacology of drugs that alter multidrug resistance in cancer
    • Ford, J. M., and W. N. Hait. 1990. Pharmacology of drugs that alter multi-drug resistance in cancer. Pharmacol. Rev. 42:155-190. (Pubitemid 20291782)
    • (1990) Pharmacological Reviews , vol.42 , Issue.3 , pp. 155-199
    • Ford, J.M.1    Hait, W.N.2
  • 14
    • 0018876983 scopus 로고
    • In vitro susceptibility of Pseudomonas aeruginosa to carbenicillin, glycine, and ethylenediaminetetraacetic acid combinations
    • Gerberick, G. F., and P. A. Castric. 1980. In vitro susceptibility of Pseudo-monas aeruginosa to carbenicillin, glycine, and ethylenediaminetetraacetic acid combinations. Antimicrob. Agents Chemother. 17:732-735. (Pubitemid 10155433)
    • (1980) Antimicrobial Agents and Chemotherapy , vol.17 , Issue.4 , pp. 732-735
    • Gerberick, G.F.1    Castric, P.A.2
  • 15
    • 0028954118 scopus 로고
    • Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG procedure
    • Gietz, R. D., R. H. Schiestl, A. R. Willems, and R. A. Woods. 1995. Studies on the transformation of intact yeast cells by the LiAc/SS-DNA/PEG pro-cedure. Yeast 11:355-360.
    • (1995) Yeast , vol.11 , pp. 355-360
    • Gietz, R.D.1    Schiestl, R.H.2    Willems, A.R.3    Woods, R.A.4
  • 16
    • 0032915204 scopus 로고    scopus 로고
    • Heterologous URA3MX cassettes for gene replacement in Saccharomyces cerevisiae
    • DOI 10.1002/(SICI)1097-0061(199904)15:6<507::AID-YEA369>3.0.CO;2-P
    • Goldstein, A. L., X. Pan, and J. H. McCusker. 1999. Heterologous URA3MX cassettes for gene replacement in Saccharomyces cerevisiae. Yeast 15:507-511. (Pubitemid 29184859)
    • (1999) Yeast , vol.15 , Issue.6 , pp. 507-511
    • Goldstein, A.L.1    Pan, X.2    McCusker, J.H.3
  • 17
    • 0020645052 scopus 로고
    • Yeast promoter and lacZ fusions designed to study expression of cloned genes in yeast
    • Guarente, L. 1983. Yeast promoter and lacZ fusions designed to study expression of cloned genes in yeast. Methods Enzymol. 101:181-191.
    • (1983) Methods Enzymol. , vol.101 , pp. 181-191
    • Guarente, L.1
  • 18
    • 0345373933 scopus 로고    scopus 로고
    • Neither lipophilicity nor membrane-perturbing potency of phenothiazine maleates correlate with the ability to inhibit P-glycoprotein transport activity
    • DOI 10.1080/0968768031000045815
    • Hendrich, A. B., O. Wesotowska, A. Pota, N. Motohashi, J. Moinar, and K. Michalak. 2003. Neither lipophilicity nor membrane-perturbing potency of phenothiazine maleates correlate with the ability to inhibit P-glycoprotein transport activity. MoI. Membr. Biol. 20:53-60. (Pubitemid 36460646)
    • (2003) Molecular Membrane Biology , vol.20 , Issue.1 , pp. 53-60
    • Hendrich, A.B.1    Wesolowska, O.2    Pola, A.3    Motohashi, N.4    Molnar, J.5    Michalak, K.6
  • 20
    • 0037308580 scopus 로고    scopus 로고
    • Phenothiazines and thioxanthenes inhibit multidrug efflux pump activity in Staphylococcus aureus
    • DOI 10.1128/AAC.47.2.719-726.2003
    • Kaatz, G. W., V. V. Moudgal, S. M. Seo, and J. E. Kristiansen. 2003. Fhenothiazines and thioxanthenes inhibit multidrug efflux pump activity in Staphylococcus aureus. Antimicrob. Agents Chemother. 47:719-726. (Pubitemid 36158106)
    • (2003) Antimicrobial Agents and Chemotherapy , vol.47 , Issue.2 , pp. 719-726
    • Kaatz, G.W.1    Moudgal, V.V.2    Seo, S.M.3    Kristiansen, J.E.4
  • 21
    • 0032915873 scopus 로고    scopus 로고
    • Mutational disruption of plasma membrane trafficking of Saccharomyces cerevisiae Yor1p, a homologue of mammalian multidrug resistance protein
    • Katzmann, D. J., E. A. Epping, and W. S. Moye-Rowley. 1999. Mutational disruption of plasma membrane trafficking of Saccharomyces cerevisiae Yorlp, a homologue of mammalian multidrug resistance protein. MbI. Cell. Biol. 19:2998-3009. (Pubitemid 29144545)
    • (1999) Molecular and Cellular Biology , vol.19 , Issue.4 , pp. 2998-3009
    • Katzmann, D.J.1    Epping, E.A.2    Moye-Rowley, W.S.3
  • 23
    • 0026040182 scopus 로고
    • Characterization of multidrug resistance by fluorescent dyes
    • Kessel, D., W. T. Beck, D. Kukuruga, and V. Schulz. 1991. Characterization of multidrug resistance by fluorescent dyes. Cancer Res. 51:4665-4670.
    • (1991) Cancer Res. , vol.51 , pp. 4665-4670
    • Kessel, D.1    Beck, W.T.2    Kukuruga, D.3    Schulz, V.4
  • 24
    • 40149095880 scopus 로고    scopus 로고
    • Compensatory activation of the multidrug transporters Pdr5p. Snq2p, and Yorlp by Fdrlp in Saccharomyces cerevisiae
    • Kolaczkowska, A., M. Kolaczkowski, A. Goffeau, and W. S. Moye-Rowley. 2008. Compensatory activation of the multidrug transporters Pdr5p. Snq2p, and Yorlp by Fdrlp in Saccharomyces cerevisiae. FEBS Lett. 582:977-983.
    • (2008) FEBS Lett. , vol.582 , pp. 977-983
    • Kolaczkowska, A.1    Kolaczkowski, M.2    Goffeau, A.3    Moye-Rowley S, W.4
  • 25
    • 0031796062 scopus 로고    scopus 로고
    • In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resistance network
    • Kolaczkowski, M., A. Kolaczowska, J. Luczynski, S. Witek, and A. Goffeau. 1998. In vivo characterization of the drug resistance profile of the major ABC transporters and other components of the yeast pleiotropic drug resis-tance network. Microb. Drug Resist. 4:143-158. (Pubitemid 28500712)
    • (1998) Microbial Drug Resistance , vol.4 , Issue.3 , pp. 143-158
    • Kolaczkowski, M.1    Kolaczkowska, A.2    Luczynski, J.3    Witek, S.4    Goffeau, A.5
  • 28
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, TJ. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 29
    • 0025237430 scopus 로고
    • Cloning by gene amplification of two loci conferring multiple drug resistance in saccharomyces
    • Leppert, G., R. McDevitt, S. C. Falco, T. K. Van Dyk, M. B. Ficke, and J. Golin. 1990. Cloning by gene amplification of two loci conferring multiple drug resistance in Saccharomyces. Genetics 125:13-20. (Pubitemid 20136290)
    • (1990) Genetics , vol.125 , Issue.1 , pp. 13-20
    • Leppert, G.1    McDevitt, R.2    Falco, S.C.3    Van Dyk, T.K.4    Ficke, M.B.5    Golin, J.6
  • 30
    • 0034610402 scopus 로고    scopus 로고
    • Intrinsic fluorescence of the F-glycoprotein multidrug transporter: Sensitivity of tryptophan residues to binding of drugs and nucleotides
    • Liu, R., A. Siemiarczuk, and F. J. Sharom. 2000. Intrinsic fluorescence of the F-glycoprotein multidrug transporter: sensitivity of tryptophan residues to binding of drugs and nucleotides. Biochemistry 39:14927-14938.
    • (2000) Biochemistry , vol.39 , pp. 14927-14938
    • Liu, R.1    Siemiarczuk, A.2    Sharom, F.J.3
  • 31
    • 0031820288 scopus 로고    scopus 로고
    • Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae
    • DOI 10.1002/(SICI)1097-0061(199807)14:10<953::AID-YEA293>3.0.CO;2-U
    • Longtine, M. S., A. McKenzie III, D. J. Demarini, N. G. Shah, A. Wach, A. Brachat, P. Philippsen, and J. R. Pringle. 1998. Additional modules for versatile and economical FCR-based gene deletion and modification in Sac-charomyces cerevisiae. Yeast 14:953-961. (Pubitemid 28328001)
    • (1998) Yeast , vol.14 , Issue.10 , pp. 953-961
    • Longtine, M.S.1    McKenzie III, A.2    Demarini, D.J.3    Shah, N.G.4    Wach, A.5    Brachat, A.6    Philippsen, P.7    Pringle, J.R.8
  • 32
    • 0029815138 scopus 로고    scopus 로고
    • The ATP binding cassette transporters Pdr5 and Snq2 of Saccharomyces cerevisiae can mediate transport of steroids in vivo
    • DOI 10.1074/jbc.271.41.25167
    • Mahé, Y., Y. Lemoine, and K. Kuchler. 1996. The ATF binding cassette transporters Fdr5 and Snq2 of Saccharomyces cerevisiae can mediate trans-port of steroids in vivo. J. Biol. Chem. 271:25167-25172. (Pubitemid 26337877)
    • (1996) Journal of Biological Chemistry , vol.271 , Issue.41 , pp. 25167-25172
    • Mahe, Y.1    Lemoine, Y.2    Kuchler, K.3
  • 33
    • 0033836026 scopus 로고    scopus 로고
    • Potent synergism of the combination of fluconazole and cyclosporine in Candida albicans
    • DOI 10.1128/AAC.44.9.2373-2381.2000
    • Marchetti, O., P. Moreillon, M. P. Glauser, J. Bille, and D. Sanglard. 2000. Potent synergism of the combination of fluconazole and cyclosporine in Candida albicans. Antimicrob. Agents Chemother. 44:2373-2381. (Pubitemid 30650882)
    • (2000) Antimicrobial Agents and Chemotherapy , vol.44 , Issue.9 , pp. 2373-2381
    • Marchetti, O.1    Moreillon, P.2    Glauser, M.P.3    Bille, J.4    Sanglard, D.5
  • 36
    • 0032832414 scopus 로고    scopus 로고
    • Yeast cells as tools for target-oriented screening
    • DOI 10.1007/s002530051525
    • Munder, T., and A. Hinnen. 1999. Yeast cells as tools for target oriented screening. Appl. Microbiol. Biotechnol. 52:311-320. (Pubitemid 29465985)
    • (1999) Applied Microbiology and Biotechnology , vol.52 , Issue.3 , pp. 311-320
    • Munder, T.1    Hinnen, A.2
  • 37
    • 0035185602 scopus 로고    scopus 로고
    • Functional expression of Candida albicans drug efflux pump Cdr1p in a Saccharomyces cerevisiae strain deficient in membrane transporters
    • DOI 10.1128/AAC.45.12.3366-3374.2001
    • Nakamura, K., M. Niimi, K. Niimi, A. R. Holmes, J. E. Yates, A. Decottig-nies, B. C. Monk, A. Goffeau, and R. D. Cannon. 2001. Functional expression of Candida albicans drug efflux pump Cdrlp in a Saccharomyces cerevisiae strain deficient in membrane transporters. Antimicrob. Agents Chemother. 45:3366-3374. (Pubitemid 33107848)
    • (2001) Antimicrobial Agents and Chemotherapy , vol.45 , Issue.12 , pp. 3366-3374
    • Nakamura, K.1    Niimi, M.2    Niimi, K.3    Holmes, A.R.4    Yates, J.E.5    Decottignies, A.6    Monk, B.C.7    Goffeau, A.8    Cannon, R.D.9
  • 38
    • 0003443223 scopus 로고    scopus 로고
    • Ap-proved standard M27-A. National Committee for Clinical Laboratoiy Stan-dards, Wayne, PA.
    • National Committee for Clinical Laboratory Standards. 1997. Reference method for broth dilution antifungal susceptibility testing of yeasts. Ap-proved standard M27-A. National Committee for Clinical Laboratoiy Stan-dards, Wayne, PA.
    • (1997) Reference method for broth dilution antifungal susceptibility testing of yeasts
  • 40
    • 0038601510 scopus 로고    scopus 로고
    • Synergy, antagonism, and what the chequerboard puts between them
    • Odds, F. C. 2003. Synergy, antagonism, and what the chequerboard puts between them. J. Antimicrob. Chemother. 52:1. (Pubitemid 36850074)
    • (2003) Journal of Antimicrobial Chemotherapy , vol.52 , Issue.1 , pp. 1
    • Odds, F.C.1
  • 41
    • 0036792188 scopus 로고    scopus 로고
    • Role of sentinel surveillance of candidemia: Trends in species distribution and antifungal susceptibility
    • Pfaller, M. A., and D. J. Diekema. 2002. Role of sentinel surveillance of candidemia: trends in species distribution and antifungal susceptibility. J. Clin. Microbiol. 40:3551-3557.
    • (2002) J. Clin. Microbiol. , vol.40 , pp. 3551-3557
    • Pfaller, M.A.1    Diekema, D.J.2
  • 43
    • 0028928549 scopus 로고
    • Molecular cloning and characterization of a novel gene of Candida albicans, CDRl, conferring multiple resistance to drugs and antifungals
    • Prasad, R., P. De Wergifosse, A. Goffeau, and E. Balzi. 1995. Molecular cloning and characterization of a novel gene of Candida albicans, CDRl, conferring multiple resistance to drugs and antifungals. Curr. Genet. 4:320-329.
    • (1995) Curr. Genet. , vol.4 , pp. 320-329
    • Prasad, R.1    De Wergifosse, P.2    Goffeau, A.3    Balzi, E.4
  • 44
    • 0028107822 scopus 로고
    • Reversal of multidrug resistance by bis(phenylalkyl)amines and structurally related compounds
    • DOI 10.1007/s002800050165
    • Ramu, A., and N. Ramu. 1992. Reversal of multidrug resistance by phe-nothiazines and structurally related compounds. Cancer Chemother. Phar-macol. 30:165-173. (Pubitemid 24261283)
    • (1994) Cancer Chemotherapy and Pharmacology , vol.34 , Issue.5 , pp. 423-430
    • Ramu, A.1    Ramu, N.2
  • 45
    • 0036270546 scopus 로고    scopus 로고
    • Cloning-free genome alterations in Saccharomyces cerevisiae using adaptamer-mediated PCR
    • DOI 10.1016/S0076-6879(02)50968-X
    • Reid, R. J. D., M. Lisby, and R. Rothstein. 2002. Cloning-free genome alterations in Saccharomyces cerevisiae using adaptamer-mediated FCR. Methods Enzymol. 350:258-277. (Pubitemid 34619496)
    • (2002) Methods in Enzymology , vol.350 , pp. 258-277
    • Reid, R.J.D.1    Lisby, M.2    Rothstein, R.3
  • 47
    • 0029820482 scopus 로고    scopus 로고
    • Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors
    • Sanglard, D., F. Ischer, M. Monod, and J. BiIIe. 1996. Susceptibilities of Candida albicans multidrug transporter mutants to various antifungal agents and other metabolic inhibitors. Antimicrob. Agents Chemother. 40:2300-2305. (Pubitemid 26328036)
    • (1996) Antimicrobial Agents and Chemotherapy , vol.40 , Issue.10 , pp. 2300-2305
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Bille, J.4
  • 48
    • 0031047670 scopus 로고    scopus 로고
    • Cloning of Candida albicans genes conferring resistance to azole antifungal agents: Characterization of CDR2, a new multidrug ABC transporter gene
    • Sanglard, D., F. Ischer, M. Monod, and J. Bille. 1997. Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characteriza-tion of CDR2, a new multidrug ABC transporter gene. Microbiology 143: 405-416. (Pubitemid 27092176)
    • (1997) Microbiology , vol.143 , Issue.2 , pp. 405-416
    • Sanglard, D.1    Ischer, F.2    Monod, M.3    Bille, J.4
  • 50
    • 0027497594 scopus 로고
    • Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitroquinoline-N-oxide and other chemicals, encodes a 169 kDa protein homologous to ATP-dependent permeases
    • DOI 10.1007/BF00277115
    • Servos, J., E. Haase, and M. Brendel. 1993. Gene SNQ2 of Saccharomyces cerevisiae, which confers resistance to 4-nitroquinoline-iV-oxide and other chemicals, encodes a 169 kDa protein homologous to ATF-dependent per-meases. MbI. Gen. Genet. 236:214-218. (Pubitemid 23055558)
    • (1993) Molecular and General Genetics , vol.236 , Issue.2-3 , pp. 214-218
    • Servos, J.1    Haase, E.2    Brendel, M.3
  • 51
    • 0347694571 scopus 로고    scopus 로고
    • Functional Characterization of Candida albicans ABC Transporter Cdr1p
    • DOI 10.1128/EC.2.6.1361-1375.2003
    • Shukla, S., P. Saini, Smriti, S. Jha, S. V. Ambudkar, and R. Prasad. 2003. Functional characterization of Candida albicans ABC transporter Cdrlp. Eukaryot. Cell 2:1361-1375. (Pubitemid 38047243)
    • (2003) Eukaryotic Cell , vol.2 , Issue.6 , pp. 1361-1375
    • Shukla, S.1    Saini, P.2    Smriti3    Jha, S.4    Ambudkar, S.V.5    Prasad, R.6
  • 52
    • 0024669291 scopus 로고
    • A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cere\>isiae
    • Sikorski, R. S., and P. Hieter. 1989. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cere\>isiae. Genetics 122:19-27.
    • (1989) Genetics , vol.122 , pp. 19-27
    • Sikorski, R.S.1    Hieter, P.2
  • 53
    • 33747849236 scopus 로고    scopus 로고
    • ELM1 is required for multidrug resistance in Saccharomyces cerevisiae
    • DOI 10.1534/genetics.106.057596
    • Souid, A. K., C. Gao, L. Wang, E. Milgrom, and W. C. Shen. 2006. ELMl is required for multidrug resistance in Saccharomyces cerevisiae. Genetics 173: 1919-1937. (Pubitemid 44285673)
    • (2006) Genetics , vol.173 , Issue.4 , pp. 1919-1937
    • Souid, A.-K.1    Gao, C.2    Wang, L.3    Milgrom, E.4    Shen, W.-C.W.5
  • 55
    • 40549126935 scopus 로고    scopus 로고
    • The ATP-binding cassette transporter-encoding gene CgSNQ2 is contributing to the CgfDÄY-dependent azole resistance of Candida glabrata
    • Torelli, R., B. Posteraro, S. Ferrari, M. La Sorda, G. Fadda, D. Sanglard, and M. Sanguinetti. 2008. The ATP-binding cassette transporter-encoding gene CgSNQ2 is contributing to the CgfDÄY-dependent azole resistance of Candida glabrata. MoI. Microbiol. 68:186-201.
    • (2008) MoI. Microbiol. , vol.68 , pp. 186-201
    • Torelli, R.1    Posteraro, B.2    Ferrari, S.3    La Sorda, M.4    Fadda, G.5    Sanglard, D.6    Sanguinetti, M.7
  • 58
    • 0029800028 scopus 로고    scopus 로고
    • Comparison of three different in vitro methods of detecting synergy: Time-kill, checkerboard, and E test
    • White, R. L., D. S. Burgess, M. Manduru, and J. A. Bosso. 1996. Comparison of three different in vitro methods of detecting synergy: time-kill, checker-board, and E test. Antimicrob. Agents Chemother. 40:1914-1918. (Pubitemid 26277815)
    • (1996) Antimicrobial Agents and Chemotherapy , vol.40 , Issue.8 , pp. 1914-1918
    • White, R.L.1    Burgess, D.S.2    Manduru, M.3    Bosso, J.A.4
  • 60
    • 0034650751 scopus 로고    scopus 로고
    • A recyclable Candida albicans URA3 cassette for PCR product-directed gene disruptions
    • DOI 10.1002/(SICI)1097-0061(20000115)16:1<65::AID-YEA508>3.0.CO;2-M
    • Wilson, R. B., D. Davis, B. M. Enloe, and A. P. Mitchell. 2000. A recyclable Candida albicans URA3 cassette for PCR product-directed gene disruptions. Yeast 16:65-70. (Pubitemid 30066097)
    • (2000) Yeast , vol.16 , Issue.1 , pp. 65-70
    • Wilson, R.B.1    Davis, D.2    Enloe, B.M.3    Mitchell, A.P.4
  • 61
    • 0035672866 scopus 로고    scopus 로고
    • Extrusion of fluorescein diacetate by multidrug-resistant Candida albicans
    • DOI 10.1046/j.1439-0507.2001.00666.x
    • Yang, H. C, Y. Mikami, T. Imai, H. Taguchi, K. Nishimura, M. Miyaji, and M. L. Branchini. 2001. Extrusion of fluorescein diacetate by multidrug-resistant Candida. Mycoses 44:368-374. (Pubitemid 34015718)
    • (2001) Mycoses , vol.44 , Issue.9-10 , pp. 368-374
    • Yang, H.-C.1    Mikami, Y.2    Imai, T.3    Taguchi, H.4    Nishimura, K.5    Miyaji, M.6    Branchini, M.L.M.7
  • 62
    • 0033003760 scopus 로고    scopus 로고
    • A simple statistical parameter for use in evaluation and validation of high throughput screening assays
    • DOI 10.1177/108705719900400206
    • Zhang, J. H., T. D. Y. Chung, and K. R. Oldenburg. 1999. A simple statistical parameter for use in evaluation and validation of high throughput screening assays. J. Biomol. Screen. 4:67-73. (Pubitemid 29278954)
    • (1999) Journal of Biomolecular Screening , vol.4 , Issue.2 , pp. 67-73
    • Zhang, J.-H.1    Chung, T.D.Y.2    Oldenburg, K.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.