Synergy, antagonism, and what the chequerboard puts between them

Journal of Antimicrobial Chemotherapy

Volumn 52, Issue 1, 2003, Pages 1-

  Odds, F C ^a  

^a UNIVERSITY OF ABERDEEN   (United Kingdom)

Author keywords

Antagonism; Antimicrobial combinations; Chequerboard; FIC index; Synergy

Indexed keywords

ANTIINFECTIVE AGENT; ANTIVIRUS AGENT;

ANALYTICAL ERROR; ANTIMICROBIAL ACTIVITY; BACTERIAL GROWTH; DRUG ANTAGONISM; DRUG EFFECT; DRUG POTENTIATION; EDITORIAL; GROWTH INHIBITION; IN VITRO STUDY; MATHEMATICAL MODEL; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; REPRODUCIBILITY;

EID: 0038601510     PISSN: 03057453     EISSN: None     Source Type: Journal    
DOI: 10.1093/jac/dkg301     Document Type: Editorial

References (5)

1. Chou, T.-C. & Talalay, P. (1984). Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Advances in Enzyme Regulation 22, 27-55.
2. Prichard, M. N., Prichard, L. E. & Shipman, C. J. (1993). Strategic design and three-dimensional analysis of antiviral drug combinations. Antimicrobial Agents & Chemotherapy 37, 540-5.
3. Greco, W. R., Bravo, G. & Parsons, J. C. (1995). The search for synergy: a critical review from a response surface perspective. Pharmacological Reviews 47, 331-85.
4. Lewis, R. E., Diekema, D. J., Messer, S. A. et al. (2002). Comparison of Etest, chequerboard dilution and time-kill studies for the detection of synergy or antagonism between antifungal agents tested against Candida species. Journal of Antimicrobial Chemotherapy 49, 345-51.
5. Rand, K. H., Houck, H. J., Brown, P. et al. (1993). Reproducibility of the microdilution checkerboard method for antibiotic synergy. Antimicrobial Agents & Chemotherapy 37, 613-5.