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Volumn 19, Issue 4, 1999, Pages 2998-3009

Mutational disruption of plasma membrane trafficking of Saccharomyces cerevisiae Yor1p, a homologue of mammalian multidrug resistance protein

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; MULTIDRUG RESISTANCE PROTEIN; MUTANT PROTEIN; OLIGOMYCIN; PHENYLALANINE; PROTEASOME; TRANSMEMBRANE CONDUCTANCE REGULATOR;

EID: 0032915873     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/mcb.19.4.2998     Document Type: Article
Times cited : (83)

References (69)
  • 1
    • 0022753540 scopus 로고
    • PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors
    • Ammerer, G., C. Hunter, J. H. Rothman, G. C. Saari, L. A. Valls, and T. H. Stevens. 1986. PEP4 gene of Saccharomyces cerevisiae encodes proteinase A, a vacuolar enzyme required for processing of vacuolar precursors. Mol. Cell. Biol. 6:2490-2499.
    • (1986) Mol. Cell. Biol. , vol.6 , pp. 2490-2499
    • Ammerer, G.1    Hunter, C.2    Rothman, J.H.3    Saari, G.C.4    Valls, L.A.5    Stevens, T.H.6
  • 3
    • 0028117116 scopus 로고
    • Metabolic instability and constitutive endocytosis of STE6, the a-factor transporter of Saccharomyces cerevisiae
    • Berkower, C., D. Loayza, and S. Michaelis. 1994. Metabolic instability and constitutive endocytosis of STE6, the a-factor transporter of Saccharomyces cerevisiae. Mol. Biol. Cell 5:1185-1198.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 1185-1198
    • Berkower, C.1    Loayza, D.2    Michaelis, S.3
  • 4
    • 0026094617 scopus 로고
    • Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette protein super-family
    • Berkower, C., and S. Michaelis. 1991. Mutational analysis of the yeast a-factor transporter STE6, a member of the ATP binding cassette protein super-family. EMBO J. 10:3777-3785.
    • (1991) EMBO J. , vol.10 , pp. 3777-3785
    • Berkower, C.1    Michaelis, S.2
  • 5
    • 0030666729 scopus 로고    scopus 로고
    • Role of Cue1p in ubiquitination and degradation at the ER surface
    • Biederer, T., C. Volkwein, and T. Sommer. 1997. Role of Cue1p in ubiquitination and degradation at the ER surface. Science 278:1806-1809.
    • (1997) Science , vol.278 , pp. 1806-1809
    • Biederer, T.1    Volkwein, C.2    Sommer, T.3
  • 6
    • 0031854866 scopus 로고    scopus 로고
    • Retrograde traffic out of the yeast vacuole to the TGN occurs via the prevacuolar/ endosomal compartment
    • Bryant, N. J., R. C. Piper, L. S. Weisman, and T. H. Stevens. 1998. Retrograde traffic out of the yeast vacuole to the TGN occurs via the prevacuolar/ endosomal compartment. J. Cell Biol. 142:651-663.
    • (1998) J. Cell Biol. , vol.142 , pp. 651-663
    • Bryant, N.J.1    Piper, R.C.2    Weisman, L.S.3    Stevens, T.H.4
  • 7
    • 0025242929 scopus 로고
    • Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis
    • Cheng, S. H., R. J. Gregory, J. Marshall, S. Paul, D. W. Souza, G. A. White, C. R. O'Riordan, and A. E. Smith. 1990. Defective intracellular transport and processing of CFTR is the molecular basis of most cystic fibrosis. Cell 63:827-834.
    • (1990) Cell , vol.63 , pp. 827-834
    • Cheng, S.H.1    Gregory, R.J.2    Marshall, J.3    Paul, S.4    Souza, D.W.5    White, G.A.6    O'Riordan, C.R.7    Smith, A.E.8
  • 9
    • 15844430252 scopus 로고    scopus 로고
    • The multidrug resistance-associated protein (MRP) subfamily (YrS1/Yor1) of Saccharomyces cerevisiae is important for the tolerance to a broad range of organic anions
    • Cui, Z., D. Hirata, E. Tsuchiya, H. Osada, and T. Miyakawa. 1996. The multidrug resistance-associated protein (MRP) subfamily (YrS1/Yor1) of Saccharomyces cerevisiae is important for the tolerance to a broad range of organic anions. J. Biol. Chem. 271:14712-14716.
    • (1996) J. Biol. Chem. , vol.271 , pp. 14712-14716
    • Cui, Z.1    Hirata, D.2    Tsuchiya, E.3    Osada, H.4    Miyakawa, T.5
  • 10
    • 0031056684 scopus 로고    scopus 로고
    • Complete inventory of the yeast ABC proteins
    • Decottignies, A., and A. Goffeau. 1997. Complete inventory of the yeast ABC proteins. Nat. Genet. 15:137-145.
    • (1997) Nat. Genet. , vol.15 , pp. 137-145
    • Decottignies, A.1    Goffeau, A.2
  • 11
    • 0028783747 scopus 로고
    • Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae
    • Egner, R., Y. Mahé, R. Pandjaitan, and K. Kuchler. 1995. Endocytosis and vacuolar degradation of the plasma membrane-localized Pdr5 ATP-binding cassette multidrug transporter in Saccharomyces cerevisiae. Mol. Cell. Biol. 15:5879-5887.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 5879-5887
    • Egner, R.1    Mahé, Y.2    Pandjaitan, R.3    Kuchler, K.4
  • 13
    • 0027137885 scopus 로고
    • Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast
    • Finger, A., M. Knop, and D. H. Wolf. 1993. Analysis of two mutated vacuolar proteins reveals a degradation pathway in the endoplasmic reticulum or a related compartment of yeast. Eur. J. Biochem. 218:565-574.
    • (1993) Eur. J. Biochem. , vol.218 , pp. 565-574
    • Finger, A.1    Knop, M.2    Wolf, D.H.3
  • 14
    • 0031907211 scopus 로고    scopus 로고
    • ER degradation of a mutant yeast plasma membrane protein by the ubiquitin-proteasome pathway
    • Galan, J.-M., B. Cantegrit, C. Garnier, O. Namy, and R. Haguenauer-Tsapis. 1998. ER degradation of a mutant yeast plasma membrane protein by the ubiquitin-proteasome pathway. FASEB J. 12:315-323.
    • (1998) FASEB J. , vol.12 , pp. 315-323
    • Galan, J.-M.1    Cantegrit, B.2    Garnier, C.3    Namy, O.4    Haguenauer-Tsapis, R.5
  • 16
    • 0027218689 scopus 로고
    • Biochemistry of multidrug resistance mediated by the multidrug transporter
    • Gottesman, M. M., and I. Pastan. 1993. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62:385-427.
    • (1993) Annu. Rev. Biochem. , vol.62 , pp. 385-427
    • Gottesman, M.M.1    Pastan, I.2
  • 17
    • 0025977037 scopus 로고
    • Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
    • Guan, K.-L., and J. E. Dixon. 1991. Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem. 192:262-267.
    • (1991) Anal. Biochem. , vol.192 , pp. 262-267
    • Guan, K.-L.1    Dixon, J.E.2
  • 18
    • 0029811218 scopus 로고    scopus 로고
    • Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein
    • Hampton, R., R. G. Gardner, and J. Rine. 1996. Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein. Mol. Biol. Cell 7:2029-2044.
    • (1996) Mol. Biol. Cell , vol.7 , pp. 2029-2044
    • Hampton, R.1    Gardner, R.G.2    Rine, J.3
  • 19
    • 0028213166 scopus 로고
    • Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast
    • Hampton, R. Y., and J. Rine. 1994. Regulated degradation of HMG-CoA reductase, an integral membrane protein of the endoplasmic reticulum, in yeast. J. Cell Biol. 125:299-312.
    • (1994) J. Cell Biol. , vol.125 , pp. 299-312
    • Hampton, R.Y.1    Rine, J.2
  • 21
    • 0027418063 scopus 로고
    • PRE2, highly homologous to the human major histocompatibility complex-linked RING10 gene, codes for a yeast proteasome subunit necessary for chymotryptic activity and degradation to ubiquitinated proteins
    • Heinemeyer, W., A. Gruhler, V. Mohrle, Y. Mahe, and D. H. Wolf. 1993. PRE2, highly homologous to the human major histocompatibility complex-linked RING10 gene, codes for a yeast proteasome subunit necessary for chymotryptic activity and degradation to ubiquitinated proteins. J. Biol. Chem. 268:5115-5120.
    • (1993) J. Biol. Chem. , vol.268 , pp. 5115-5120
    • Heinemeyer, W.1    Gruhler, A.2    Mohrle, V.3    Mahe, Y.4    Wolf, D.H.5
  • 22
    • 0025980627 scopus 로고
    • Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: Mutants unravel its function in stress-induced proteolysis and uncover its necessity for cell survival
    • Heinemeyer, W., J. A. Kleinschmidt, J. Saidowsky, C. Escher, and D. H. Wolf. 1991. Proteinase yscE, the yeast proteasome/multicatalytic-multifunctional proteinase: mutants unravel its function in stress-induced proteolysis and uncover its necessity for cell survival. EMBO J. 10:555-562.
    • (1991) EMBO J. , vol.10 , pp. 555-562
    • Heinemeyer, W.1    Kleinschmidt, J.A.2    Saidowsky, J.3    Escher, C.4    Wolf, D.H.5
  • 23
    • 0030700220 scopus 로고    scopus 로고
    • Ubiquitin-dependent internalization and down-regulation of plasma membrane proteins
    • Hicke, L. 1997. Ubiquitin-dependent internalization and down-regulation of plasma membrane proteins. FASEB J. 11:1215-1226.
    • (1997) FASEB J. , vol.11 , pp. 1215-1226
    • Hicke, L.1
  • 24
    • 0029838640 scopus 로고    scopus 로고
    • ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway
    • Killer, M. M., A. Finger, M. Schweiger, and D. H. Wolf. 1996. ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway. Science 273:1725-1728.
    • (1996) Science , vol.273 , pp. 1725-1728
    • Killer, M.M.1    Finger, A.2    Schweiger, M.3    Wolf, D.H.4
  • 25
    • 0030457014 scopus 로고    scopus 로고
    • Ubiquitin-dependent protein degradation
    • Hochstrasser, M. 1996. Ubiquitin-dependent protein degradation. Annu. Rev. Genet. 30:405-439.
    • (1996) Annu. Rev. Genet. , vol.30 , pp. 405-439
    • Hochstrasser, M.1
  • 27
    • 0020529962 scopus 로고
    • Transformation of intact yeast cells treated with alkali cations
    • Ito, H., Y. Fukuda, K. Murata, and A. Kimura. 1983. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153:163-168.
    • (1983) J. Bacteriol. , vol.153 , pp. 163-168
    • Ito, H.1    Fukuda, Y.2    Murata, K.3    Kimura, A.4
  • 28
    • 0028001416 scopus 로고
    • ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein
    • Jedlitschky, G., I. Leier, U. Buchholz, M. Center, and D. Keppler. 1994. ATP-dependent transport of glutathione S-conjugates by the multidrug resistance-associated protein. Cancer Res. 54:4833-4836.
    • (1994) Cancer Res. , vol.54 , pp. 4833-4836
    • Jedlitschky, G.1    Leier, I.2    Buchholz, U.3    Center, M.4    Keppler, D.5
  • 29
    • 0028858161 scopus 로고
    • Multiple proteolytic systems, including the proteasome, contribute to CFTR processing
    • Jensen, T. J., M. A. Loo, S. Pind, D. B. Williams, A. Goldberg, and J. R. Riordan. 1995. Multiple proteolytic systems, including the proteasome, contribute to CFTR processing. Cell 83:129-135.
    • (1995) Cell , vol.83 , pp. 129-135
    • Jensen, T.J.1    Loo, M.A.2    Pind, S.3    Williams, D.B.4    Goldberg, A.5    Riordan, J.R.6
  • 30
    • 0032576605 scopus 로고    scopus 로고
    • Aggresomes: A cellular response to misfolded proteins
    • Johnston, J. A., C. L. Ward, and R. R. Kopito. 1998. Aggresomes: a cellular response to misfolded proteins. J. Cell Biol. 143:1883-1898.
    • (1998) J. Cell Biol. , vol.143 , pp. 1883-1898
    • Johnston, J.A.1    Ward, C.L.2    Kopito, R.R.3
  • 31
    • 0020338057 scopus 로고
    • PEP4 gene function is required for expression of several vacuolar hydrolases in Saccharomyces cerevisiae
    • Jones, E. W., G. S. Zubenko, and R. R. Parker. 1982. PEP4 gene function is required for expression of several vacuolar hydrolases in Saccharomyces cerevisiae. Genetics 102:665-667.
    • (1982) Genetics , vol.102 , pp. 665-667
    • Jones, E.W.1    Zubenko, G.S.2    Parker, R.R.3
  • 32
    • 0027511214 scopus 로고
    • Resistance to cadmium mediated by ubiquitin-dependent proteolysis
    • Jungmann, J., H.-A. Reins, C. Schobert, and S. Jentsch. 1993. Resistance to cadmium mediated by ubiquitin-dependent proteolysis. Nature 361:369-371.
    • (1993) Nature , vol.361 , pp. 369-371
    • Jungmann, J.1    Reins, H.-A.2    Schobert, C.3    Jentsch, S.4
  • 33
    • 0028807740 scopus 로고
    • Expression of an ATP-binding cassette transporter-encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae
    • Katzmann, D. J., T. C. Hallstrom, M. Voet, W. Wysock, J. Golin, G. Volckaert, and W. S. Moye-Rowley. 1995. Expression of an ATP-binding cassette transporter-encoding gene (YOR1) is required for oligomycin resistance in Saccharomyces cerevisiae. Mol. Cell. Biol. 15:6875-6883.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6875-6883
    • Katzmann, D.J.1    Hallstrom, T.C.2    Voet, M.3    Wysock, W.4    Golin, J.5    Volckaert, G.6    Moye-Rowley, W.S.7
  • 34
    • 0031160517 scopus 로고    scopus 로고
    • Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver
    • Keppler, D., and J. Konig. 1997. Expression and localization of the conjugate export pump encoded by the MRP2 (cMRP/cMOAT) gene in liver. FASEB J. 11:509-516.
    • (1997) FASEB J. , vol.11 , pp. 509-516
    • Keppler, D.1    Konig, J.2
  • 35
    • 0028277963 scopus 로고
    • The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants
    • Rolling, R., and C. P. Hollenberg. 1994. The ABC-transporter Ste6 accumulates in the plasma membrane in a ubiquitinated form in endocytosis mutants. EMBO J. 13:3261-3271.
    • (1994) EMBO J. , vol.13 , pp. 3261-3271
    • Rolling, R.1    Hollenberg, C.P.2
  • 37
    • 0029983266 scopus 로고    scopus 로고
    • The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump
    • Li, Z.-S., M. Szczypka, Y.-P. Lu, D. J. Thiele, and P. A. Rea. 1996. The yeast cadmium factor protein (YCF1) is a vacuolar glutathione S-conjugate pump. J. Biol. Chem. 271:6509-6517.
    • (1996) J. Biol. Chem. , vol.271 , pp. 6509-6517
    • Li, Z.-S.1    Szczypka, M.2    Lu, Y.-P.3    Thiele, D.J.4    Rea, P.A.5
  • 38
    • 0031690373 scopus 로고    scopus 로고
    • Ste6p mutants defective in exit from the endoplasmic reticulum reveal aspects of an ER quality control pathway in Saccharomyces cerevisiae
    • Loayza, D., A. Tam, W. K. Schmidt, and S. Michaelis. 1998. Ste6p mutants defective in exit from the endoplasmic reticulum reveal aspects of an ER quality control pathway in Saccharomyces cerevisiae. Mol. Biol. Cell 9:2767-2784.
    • (1998) Mol. Biol. Cell , vol.9 , pp. 2767-2784
    • Loayza, D.1    Tam, A.2    Schmidt, W.K.3    Michaelis, S.4
  • 39
    • 0030962253 scopus 로고    scopus 로고
    • ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene
    • Loe, D. W., R. K. Stewart, T. E. Massey, R. G. Deeley, and S. P. C. Cole. 1997. ATP-dependent transport of aflatoxin B1 and its glutathione conjugates by the product of the multidrug resistance protein (MRP) gene. Mol. Pharmacol. 51:1034-1041.
    • (1997) Mol. Pharmacol. , vol.51 , pp. 1034-1041
    • Loe, D.W.1    Stewart, R.K.2    Massey, T.E.3    Deeley, R.G.4    Cole, S.P.C.5
  • 41
    • 0028559511 scopus 로고
    • Conformational maturation of CFTR but not its mutant counterpart (ΔF508) occurs in the endoplasmic reticulum and requires ATP
    • Lukacs, G. L., A. Mohamed, N. Kartner, X.-B. Chang, J. R. Riordan, and S. Grinstein. 1994. Conformational maturation of CFTR but not its mutant counterpart (ΔF508) occurs in the endoplasmic reticulum and requires ATP. EMBO J. 13:6076-6086.
    • (1994) EMBO J. , vol.13 , pp. 6076-6086
    • Lukacs, G.L.1    Mohamed, A.2    Kartner, N.3    Chang, X.-B.4    Riordan, J.R.5    Grinstein, S.6
  • 43
    • 0028332917 scopus 로고
    • The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene
    • Marcusson, E. G., B. F. Horazdovsky, J. L. Cereghino, E. Gharakhanian, and S. D. Emr. 1994. The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene. Cell 77:579-586.
    • (1994) Cell , vol.77 , pp. 579-586
    • Marcusson, E.G.1    Horazdovsky, B.F.2    Cereghino, J.L.3    Gharakhanian, E.4    Emr, S.D.5
  • 44
    • 0029556086 scopus 로고
    • Sequence comparison of yeast ATP-binding cassette transporter proteins
    • Michaelis, S., and C. Berkower. 1995. Sequence comparison of yeast ATP-binding cassette transporter proteins. Cold Spring Harbor Symp. Quant. Biol. 60:291-307.
    • (1995) Cold Spring Harbor Symp. Quant. Biol. , vol.60 , pp. 291-307
    • Michaelis, S.1    Berkower, C.2
  • 45
    • 0028578004 scopus 로고
    • Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport
    • Muller, M., C. Meijer, G. J. R. Zaman, P. Borst, R. J. Scheper, N. H. Mulder, E. G. E. de Vries, and P. L. M. Jansen. 1994. Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport. Proc. Natl. Acad. Sci. USA 91:13033-13037.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 13033-13037
    • Muller, M.1    Meijer, C.2    Zaman, G.J.R.3    Borst, P.4    Scheper, R.J.5    Mulder, N.H.6    De Vries, E.G.E.7    Jansen, P.L.M.8
  • 46
    • 0024075376 scopus 로고
    • A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast
    • Nakano, A., D. Brada, and R. Schekman. 1988. A membrane glycoprotein, Sec12p, required for protein transport from the endoplasmic reticulum to the Golgi apparatus in yeast. J. Cell Biol. 107:851-863.
    • (1988) J. Cell Biol. , vol.107 , pp. 851-863
    • Nakano, A.1    Brada, D.2    Schekman, R.3
  • 47
    • 0029976308 scopus 로고    scopus 로고
    • Analysis of the localization of STE6/CFTR chimeras in a Saccharomyces cerevisiae model for the cystic fibrosis defect CFTRΔF508
    • Paddon, C., D. Loayza, L. Vangelista, R. Solari, and S. Michaelis. 1996. Analysis of the localization of STE6/CFTR chimeras in a Saccharomyces cerevisiae model for the cystic fibrosis defect CFTRΔF508. Mol. Microbiol. 19:1007-1017.
    • (1996) Mol. Microbiol. , vol.19 , pp. 1007-1017
    • Paddon, C.1    Loayza, D.2    Vangelista, L.3    Solari, R.4    Michaelis, S.5
  • 50
    • 0032484024 scopus 로고    scopus 로고
    • Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome
    • Plemper, R. K., R. Egner, K. Kuchler, and D. H. Wolf. 1998. Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome. J. Biol. Chem. 273:32848-32856.
    • (1998) J. Biol. Chem. , vol.273 , pp. 32848-32856
    • Plemper, R.K.1    Egner, R.2    Kuchler, K.3    Wolf, D.H.4
  • 53
    • 0030990121 scopus 로고    scopus 로고
    • Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae
    • Roberg, K. J., N. Rowley, and C. Kaiser. 1997. Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae. J. Cell Biol. 137:1469-1482.
    • (1997) J. Cell Biol. , vol.137 , pp. 1469-1482
    • Roberg, K.J.1    Rowley, N.2    Kaiser, C.3
  • 57
    • 0028224534 scopus 로고
    • Cell biological mechanisms of multidrug resistance in tumors
    • Simon, S. M., and M. Schindler. 1994. Cell biological mechanisms of multidrug resistance in tumors. Proc. Natl. Acad. Sci. USA 91:3497-3504.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3497-3504
    • Simon, S.M.1    Schindler, M.2
  • 58
    • 0020181690 scopus 로고
    • Early stages in the yeast secretory pathway are required for the transport of carboxypeptidase y to the vacuole
    • Stevens, T. H., B. Esmon, and R. Schekman. 1982. Early stages in the yeast secretory pathway are required for the transport of carboxypeptidase Y to the vacuole. Cell 30:439-448.
    • (1982) Cell , vol.30 , pp. 439-448
    • Stevens, T.H.1    Esmon, B.2    Schekman, R.3
  • 59
    • 0027058051 scopus 로고
    • Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic rcticulum
    • Stirling, C. J., J. Rothblatt, M. Hosobuchi, R. Deshaies, and R. Schekman. 1992. Protein translocation mutants defective in the insertion of integral membrane proteins into the endoplasmic rcticulum. Mol. Biol. Cell 3:129-142.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 129-142
    • Stirling, C.J.1    Rothblatt, J.2    Hosobuchi, M.3    Deshaies, R.4    Schekman, R.5
  • 60
    • 0028064872 scopus 로고
    • A yeast metal resistance protein similar to human CFTR and multidrug resistance-associated protein
    • Szczypka, M. S., J. A. Wemmie, W. S. Moye-Rowley, and D. J. Thiele. 1994. A yeast metal resistance protein similar to human CFTR and multidrug resistance-associated protein. J. Biol. Chem. 269:22853-22857.
    • (1994) J. Biol. Chem. , vol.269 , pp. 22853-22857
    • Szczypka, M.S.1    Wemmie, J.A.2    Moye-Rowley, W.S.3    Thiele, D.J.4
  • 61
    • 0027153083 scopus 로고
    • Identification of revertants for the cystic fibrosis ΔF508 mutation using STE6-CFTR chimeras in yeast
    • Teem, J. L., H. A. Berger, L. S. Ostedgaard, D. P. Rich, L.-C. Tsui, and M. J. Welsh. 1993. Identification of revertants for the cystic fibrosis ΔF508 mutation using STE6-CFTR chimeras in yeast. Cell 73:335-346.
    • (1993) Cell , vol.73 , pp. 335-346
    • Teem, J.L.1    Berger, H.A.2    Ostedgaard, L.S.3    Rich, D.P.4    Tsui, L.-C.5    Welsh, M.J.6
  • 62
    • 0026641782 scopus 로고
    • The spectrum of cystic fibrosis mutations
    • Tsui, L.-C. 1992. The spectrum of cystic fibrosis mutations. Trends Genet. 8:392-398.
    • (1992) Trends Genet. , vol.8 , pp. 392-398
    • Tsui, L.-C.1
  • 63
  • 64
    • 0001607723 scopus 로고
    • Distantly related sequences in the alpha and beta subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold
    • Walker, J. E., M. Saraste, M. J. Runswick, and N. Gay. 1982. Distantly related sequences in the alpha and beta subunits of ATP synthase, myosin, kinases and other ATP-requiring enzymes and a common nucleotide binding fold. EMBO J. 8:945-951.
    • (1982) EMBO J. , vol.8 , pp. 945-951
    • Walker, J.E.1    Saraste, M.2    Runswick, M.J.3    Gay, N.4
  • 65
    • 0028840915 scopus 로고
    • Degradation of CFTR by the ubiquitin-proteasome pathway
    • Ward, C. L., S. Omura, and R. R. Kopito. 1995. Degradation of CFTR by the ubiquitin-proteasome pathway. Cell 83:121-127.
    • (1995) Cell , vol.83 , pp. 121-127
    • Ward, C.L.1    Omura, S.2    Kopito, R.R.3
  • 66
    • 0027162649 scopus 로고
    • Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis
    • Welsh, M. J., and A. E. Smith. 1993. Molecular mechanisms of CFTR chloride channel dysfunction in cystic fibrosis. Cell 73:1251-1254.
    • (1993) Cell , vol.73 , pp. 1251-1254
    • Welsh, M.J.1    Smith, A.E.2
  • 67
    • 0030771930 scopus 로고    scopus 로고
    • Mutational analysis of the Saccharomyces cerevisiae ATP-binding cassette transporter protein Ycf1p
    • Wemmie, J. A., and W. S. Moye-Rowley. 1997. Mutational analysis of the Saccharomyces cerevisiae ATP-binding cassette transporter protein Ycf1p. Mol. Microbiol. 25:683-694.
    • (1997) Mol. Microbiol. , vol.25 , pp. 683-694
    • Wemmie, J.A.1    Moye-Rowley, W.S.2
  • 68
    • 0030447659 scopus 로고    scopus 로고
    • Proteasome-dependent endoplasmic rcticulum degradation: An unconventional route to a familiar fate
    • Werner, E. D., J. L. Brodskj, and A. A. McCracken. 1996. Proteasome-dependent endoplasmic rcticulum degradation: an unconventional route to a familiar fate. Proc. Natl. Acad. Sci. USA 93:13797-13801.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 13797-13801
    • Werner, E.D.1    Brodskj, J.L.2    McCracken, A.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.