-
1
-
-
0033040998
-
Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus
-
Aeschlimann, J. R., L. D. Dresser, G. W. Kaatz, and M. J. Rybak. 1999. Effects of NorA inhibitors on in vitro antibacterial activities and postantibiotic effects of levofloxacin, ciprofloxacin, and norfloxacin in genetically related strains of Staphylococcus aureus. Antimicrob. Agents Chemother. 43: 335-340.
-
(1999)
Antimicrob. Agents Chemother.
, vol.43
, pp. 335-340
-
-
Aeschlimann, J.R.1
Dresser, L.D.2
Kaatz, G.W.3
Rybak, M.J.4
-
2
-
-
0027160409
-
Mutants of the Bacillus subtilis multidrug transporter Bmr with altered sensitivity to the antihypertensive alkaloid reserpine
-
Ahmed, M., C. M. Borsch, A. A. Neyfakh, and S. Schuldiner. 1993. Mutants of the Bacillus subtilis multidrug transporter Bmr with altered sensitivity to the antihypertensive alkaloid reserpine. J. Biol. Chem. 268:11086-11089.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11086-11089
-
-
Ahmed, M.1
Borsch, C.M.2
Neyfakh, A.A.3
Schuldiner, S.4
-
3
-
-
0029013337
-
Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated
-
Ahmed, M., L. Lyass, P. N. Markham, S. S. Taylor, N. Vazquez-Laslop, and A. A. Neyfakh. 1995. Two highly similar multidrug transporters of Bacillus subtilis whose expression is differentially regulated. J. Bacteriol. 177:3904-3910.
-
(1995)
J. Bacteriol.
, vol.177
, pp. 3904-3910
-
-
Ahmed, M.1
Lyass, L.2
Markham, P.N.3
Taylor, S.S.4
Vazquez-Laslop, N.5
Neyfakh, A.A.6
-
4
-
-
0030918973
-
Apparent involvement of a multidrug transporter in the fluoroquinolone resistance of Streptococcus pneumoniae
-
Baranova, N., and A. A. Neyfakh. 1997. Apparent involvement of a multidrug transporter in the fluoroquinolone resistance of Streptococcus pneumoniae. Antimicrob. Agents Chemother. 41:1396-1398.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1396-1398
-
-
Baranova, N.1
Neyfakh, A.A.2
-
5
-
-
0002492795
-
Plasmids
-
C. R. Harwood and S. M. Cutting (ed.), John Wiley & Sons, Chichester, United Kingdom
-
Bron, S. 1990. Plasmids, p. 75-174. In C. R. Harwood and S. M. Cutting (ed.), Molecular biological methods for Bacillus. John Wiley & Sons, Chichester, United Kingdom.
-
(1990)
Molecular Biological Methods for Bacillus
, pp. 75-174
-
-
Bron, S.1
-
6
-
-
0029120727
-
In vitro activity of fluoroquinolones against gram positive bacteria
-
Eliopoulus, G. M. 1995. In vitro activity of fluoroquinolones against gram positive bacteria. Drugs 49(Suppl. 2):48-57.
-
(1995)
Drugs
, vol.49
, Issue.2 SUPPL.
, pp. 48-57
-
-
Eliopoulus, G.M.1
-
7
-
-
0002515716
-
Antimicrobial combinations
-
V. Lorian (ed.) The Williams & Wilkins Co., Baltimore, Md.
-
Eliopoulus, G. M., and R. C. Moellering, Jr. 1996. Antimicrobial combinations, p. 330-396. In V. Lorian (ed.) Antibiotics in laboratory medicine, 4th ed. The Williams & Wilkins Co., Baltimore, Md.
-
(1996)
Antibiotics in Laboratory Medicine, 4th Ed.
, pp. 330-396
-
-
Eliopoulus, G.M.1
Moellering R.C., Jr.2
-
8
-
-
0027956736
-
Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: A primary target of fluoroquinolones
-
Ferrera, L., B. Cameron, B. Manse, D. Lagneaux, J. Crouzet, A. Famechon, and F. Blanche. 1994. Cloning and primary structure of Staphylococcus aureus DNA topoisomerase IV: a primary target of fluoroquinolones. Mol. Microbiol. 13:641-653.
-
(1994)
Mol. Microbiol.
, vol.13
, pp. 641-653
-
-
Ferrera, L.1
Cameron, B.2
Manse, B.3
Lagneaux, D.4
Crouzet, J.5
Famechon, A.6
Blanche, F.7
-
9
-
-
0029145907
-
Epidemiology of quinolone resistance: Europe and North and South America
-
Goldstein, F. W., and J. F. Acar. 1995. Epidemiology of quinolone resistance: Europe and North and South America. Drugs 49(Suppl. 2):36-42.
-
(1995)
Drugs
, vol.49
, Issue.2 SUPPL.
, pp. 36-42
-
-
Goldstein, F.W.1
Acar, J.F.2
-
10
-
-
0032499778
-
Bacteria lacking a multidrug pump: A sensitive tool for drug discovery
-
Hsieh, P. C., S. A. Siegel, B. Rogers, D. Davis, and K. Lewis. 1998. Bacteria lacking a multidrug pump: a sensitive tool for drug discovery. Proc. Natl. Acad. Sci. USA 95:6602-6606.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 6602-6606
-
-
Hsieh, P.C.1
Siegel, S.A.2
Rogers, B.3
Davis, D.4
Lewis, K.5
-
11
-
-
0030778138
-
Mechanisms of fluoroquinolone resistance in genetically related strains of Staphylococcus aureus
-
Kaatz, G., and S. M. Seo. 1997. Mechanisms of fluoroquinolone resistance in genetically related strains of Staphylococcus aureus, Antimicrob. Agents Chemother. 41:2733-2737.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 2733-2737
-
-
Kaatz, G.1
Seo, S.M.2
-
12
-
-
0025881139
-
Mechanisms of fluoroquinolone resistance in Staphylococcus aureus
-
Kaatz, G. W., S. M. Seo, and C. A. Ruble. 1990. Mechanisms of fluoroquinolone resistance in Staphylococcus aureus. J. Infect. Dis. 163:1080-1086.
-
(1990)
J. Infect. Dis.
, vol.163
, pp. 1080-1086
-
-
Kaatz, G.W.1
Seo, S.M.2
Ruble, C.A.3
-
13
-
-
0027270540
-
Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus
-
Kaatz, G. W., S. M. Seo, and C. A. Ruble. 1993. Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus. Antimicrob. Agents Chemother. 37:1086-1094.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 1086-1094
-
-
Kaatz, G.W.1
Seo, S.M.2
Ruble, C.A.3
-
14
-
-
0028859486
-
Inducible NorA-mediated multidrug resistance in Staphylococcus aureus
-
Kaatz, G. W., and S. Seo. 1995. Inducible NorA-mediated multidrug resistance in Staphylococcus aureus. Antimicrob. Agents Chemother. 39:2650-2655.
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 2650-2655
-
-
Kaatz, G.W.1
Seo, S.2
-
15
-
-
0030949566
-
Mutations affecting substrate specificity of the Bacillus subtilis multidrug transporter Bmr
-
Klyachko, K., S. Schuldiner, and A. A. Neyfakh. 1997. Mutations affecting substrate specificity of the Bacillus subtilis multidrug transporter Bmr. J. Bacteriol. 179:2189-2193.
-
(1997)
J. Bacteriol.
, vol.179
, pp. 2189-2193
-
-
Klyachko, K.1
Schuldiner, S.2
Neyfakh, A.A.3
-
16
-
-
0030893430
-
Active efflux of antimicrobial agents in wild-type strains of enterococci
-
Lynch, C., P. Courvalin, and H. Nikaido. 1997. Active efflux of antimicrobial agents in wild-type strains of enterococci. Antimicrob. Agents Chemother. 41:869-871.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 869-871
-
-
Lynch, C.1
Courvalin, P.2
Nikaido, H.3
-
17
-
-
0345617132
-
-
Unpublished data
-
16a. Markham, P. N. Unpublished data.
-
-
-
Markham, P.N.1
-
18
-
-
0029973621
-
Inhibition of the multidrug transporter NorA prevents emergence of norfloxacin resistance in Staphylococcus aureus
-
Markham, P. N., and A. A. Neyfakh. 1996. Inhibition of the multidrug transporter NorA prevents emergence of norfloxacin resistance in Staphylococcus aureus. Antimicrob. Agents Chemother. 40:2673-2674.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 2673-2674
-
-
Markham, P.N.1
Neyfakh, D.A.A.2
-
20
-
-
0026569448
-
The multidrug efflux transporter of Bacillus subtilis is a structural and functional homolog of the Staphylococcus NorA protein
-
Neyfakh, A. A. 1992. The multidrug efflux transporter of Bacillus subtilis is a structural and functional homolog of the Staphylococcus NorA protein. Antimicrob. Agents Chemother. 36:484-485.
-
(1992)
Antimicrob. Agents Chemother.
, vol.36
, pp. 484-485
-
-
Neyfakh, A.A.1
-
21
-
-
0027514765
-
Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter
-
Neyfakh, A. A., C. M. Borsch, and G. W. Kaatz. 1993. Fluoroquinolone resistance protein NorA of Staphylococcus aureus is a multidrug efflux transporter. Antimicrob. Agents Chemother. 37:128-129.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 128-129
-
-
Neyfakh, A.A.1
Borsch, C.M.2
Kaatz, G.W.3
-
22
-
-
0032445682
-
The effect of reserpine, an inhibitor of multidrug efflux pumps, on the in vitro activities of ciprofloxacin, sparfloxacin and moxifloxacin against clinical isolates of S. aureus
-
Schmitz, F.-J., A. C. Fluit, M. Luckefahr, B. Engler, B. Hofmann, J. Verhoef, H.-P. Heinz, U. Hadding, and M. E. Jones. 1998. The effect of reserpine, an inhibitor of multidrug efflux pumps, on the in vitro activities of ciprofloxacin, sparfloxacin and moxifloxacin against clinical isolates of S. aureus. J. Antimicrob. Chemother. 42:807-810.
-
(1998)
J. Antimicrob. Chemother.
, vol.42
, pp. 807-810
-
-
Schmitz, F.-J.1
Fluit, A.C.2
Luckefahr, M.3
Engler, B.4
Hofmann, B.5
Verhoef, J.6
Heinz, H.-P.7
Hadding, U.8
Jones, M.E.9
-
23
-
-
0025633157
-
DNA gyrase gyrA mutations in ciprofloxacin-resistant strains of Staphylococcus aureus: Close similarity with quinolone resistance mutations in Escherichia coli
-
Sreedharan, S., M. Oram, B. Jensen, L. R. Peterson, and L. M. Fisher. 1990. DNA gyrase gyrA mutations in ciprofloxacin-resistant strains of Staphylococcus aureus: close similarity with quinolone resistance mutations in Escherichia coli. J. Bacteriol. 172:7260-7262.
-
(1990)
J. Bacteriol.
, vol.172
, pp. 7260-7262
-
-
Sreedharan, S.1
Oram, M.2
Jensen, B.3
Peterson, L.R.4
Fisher, L.M.5
-
24
-
-
0030966409
-
Kinetics of the multidrug transporter (P-glycoprotein) and its reversal
-
Stein, W. D. 1997. Kinetics of the multidrug transporter (P-glycoprotein) and its reversal. Physiol. Rev. 77:545-589.
-
(1997)
Physiol. Rev.
, vol.77
, pp. 545-589
-
-
Stein, W.D.1
-
25
-
-
0031728942
-
Examination of methicillin-resistant and methicillin-susceptible Staphylococcus aureus mutants with low-level fluoroquinolone resistance
-
Sulavik, M. C., and N. L. Barg. 1998. Examination of methicillin-resistant and methicillin-susceptible Staphylococcus aureus mutants with low-level fluoroquinolone resistance. Antimicrob. Agents Chemother. 42:3317-3319.
-
(1998)
Antimicrob. Agents Chemother.
, vol.42
, pp. 3317-3319
-
-
Sulavik, M.C.1
Barg, N.L.2
-
26
-
-
0345617119
-
-
The Top 200 Prescriptions. U.S. prescriptions. [Online.] RxList .Com, Inc. 27 August, 1999
-
The Top 200 Prescriptions. 1999. 1998 U.S. prescriptions. [Online.] RxList .Com, Inc. http://www.rxlist.com/top200a.htm. [27 August, 1999, last date accessed.]
-
(1998)
-
-
-
27
-
-
0025998454
-
A novel locus conferring fluoroquinolone resistance in Staphylococcus aureus
-
Trucksis, M., J. S. Wolfson, and D. C. Hooper. 1991. A novel locus conferring fluoroquinolone resistance in Staphylococcus aureus. J. Bacteriol. 173: 5854-5860.
-
(1991)
J. Bacteriol.
, vol.173
, pp. 5854-5860
-
-
Trucksis, M.1
Wolfson, J.S.2
Hooper, D.C.3
-
28
-
-
0030840548
-
Quinolone susceptibility of norA-disrupted Staphylococcus aureus
-
Yamada, H., S. Kurose-Hamada, Y. Fukuda, J. Mitsuyama, M. Takahata, S. Minami, Y. Watanabe, and H. Narita. 1997. Quinolone susceptibility of norA-disrupted Staphylococcus aureus. Antimicrob. Agents and Chemother. 41:2308-2309.
-
(1997)
Antimicrob. Agents and Chemother.
, vol.41
, pp. 2308-2309
-
-
Yamada, H.1
Kurose-Hamada, S.2
Fukuda, Y.3
Mitsuyama, J.4
Takahata, M.5
Minami, S.6
Watanabe, Y.7
Narita, H.8
-
29
-
-
0025688065
-
Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones
-
Yoshida, H., M. Bogaki, S. Nakamura, K. Ubukata, and M. Konno. 1990. Nucleotide sequence and characterization of the Staphylococcus aureus norA gene, which confers resistance to quinolones. J. Bacteriol. 172:6942-6949.
-
(1990)
J. Bacteriol.
, vol.172
, pp. 6942-6949
-
-
Yoshida, H.1
Bogaki, M.2
Nakamura, S.3
Ubukata, K.4
Konno, M.5
-
30
-
-
0030805166
-
Active efflux as a mechanism of resistance to ciprofloxacin in Streptococcus pneumoniae
-
Zeller, V., C. Janoir, M. Kitzis, L. Gutmann, and N. J. Moreau. 1997. Active efflux as a mechanism of resistance to ciprofloxacin in Streptococcus pneumoniae. Antimicrob. Agents Chemother. 41:1973-1978.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1973-1978
-
-
Zeller, V.1
Janoir, C.2
Kitzis, M.3
Gutmann, L.4
Moreau, N.J.5
|