The involvement of autoimmunity against retinal antigens in determining disease severity in toxoplasmosis

Journal of Autoimmunity

Volumn 24, Issue 1, 2005, Pages 25-32

  Vallochi, Adriana Lima ^a   Da Silva Rios, Lília ^a   Nakamura, Marceli Vicente ^a   Silveira, Cláudio ^b   Muccioli, Cristina ^b   Martins, Maria Cristina ^b   Belfort, Rubens ^b   Rizzo, Luiz Vicente ^a,c,d  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

^c FUNDAÇÃO ZERBINI   (Brazil)

^d Inst Investigaçao Em I   (Brazil)

Author keywords

Autoimmunity; IRBP; Ocular toxoplasmosis; Retinal antigens; S Ag; Toxoplasma gondii

Indexed keywords

INTERLEUKIN 4; INTERLEUKIN 5; RETINA ANTIGEN;

ANTIBODY TITER; ARTICLE; AUTOIMMUNITY; CELL PROLIFERATION; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOKINE PRODUCTION; DISEASE COURSE; DISEASE MARKER; DISEASE SEVERITY; FEMALE; FREQUENCY ANALYSIS; HUMAN; IMMUNOPATHOGENESIS; MAJOR CLINICAL STUDY; MALE; MONONUCLEAR CELL; PARAMETER; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; TOXOPLASMA GONDII; TOXOPLASMOSIS;

EID: 13944272974     PISSN: 08968411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaut.2004.11.003     Document Type: Article

References (42)

1. A.M. Tenter, A.R. Heckeroth, and L.M. Weiss Toxoplasma gondii: from animals to humans Int J Parasitol 30 12-13 2000 1217 1258
2. C. Silveira, R. Belfort Jr., M. Burnier Jr., and R. Nussenblatt Acquired toxoplasmic infection as the cause of toxoplasmic retinochoroiditis in families Am J Ophthalmol 106 3 1988 362 364
3. R.B. Nussenblatt, and R. Belfort Jr. Ocular toxoplasmosis. An old disease revisited JAMA 271 4 1994 304 307
4. F. Bertoli, M. Espino, J.Rt. Arosemena, J.L. Fishback, and J.K. Frenkel A spectrum in the pathology of toxoplasmosis in patients with acquired immunodeficiency syndrome Arch Pathol Lab Med 119 3 1995 214 224
5. E.S. Perkins Ocular toxoplasmosis Bull Ophthalmol Soc Egypt 60 64 1967 523 527
6. E.S. Perkins Toxoplasmosis Br Med J 4 831 1972 46
7. B.J. Luft, R.G. Brooks, F.K. Conley, R.E. McCabe, and J.S. Remington Toxoplasmic encephalitis in patients with acquired immune deficiency syndrome JAMA 252 7 1984 913 917
8. B.A. Navia, C.K. Petito, J.W. Gold, E.S. Cho, B.D. Jordan, and R.W. Price Cerebral toxoplasmosis complicating the acquired immune deficiency syndrome: clinical and neuropathological findings in 27 patients Ann Neurol 19 3 1986 224 238
9. P.D. Glasner, C. Silveira, D. Kruszon-Moran, M.C. Martins, M. Burnier Jr, and S. Silveira An unusually high prevalence of ocular toxoplasmosis in southern Brazil Am J Ophthalmol 114 2 1992 136 144
10. A.L. Vallochi, M.V. Nakamura, D. Schlesinger, M.C. Martins, C. Silveira, and R. Belfort Jr. Ocular toxoplasmosis: more than just what meets the eye Scand J Immunol 55 4 2002 324 328
11. J.H. Yamamoto, A.L. Vallochi, C. Silveira, J.K. Filho, R.B. Nussenblatt, and E. Cunha-Neto Discrimination between patients with acquired toxoplasmosis and congenital toxoplasmosis on the basis of the immune response to parasite antigens J Infect Dis 181 6 2000 2018 2022
12. R.B. Nussenblatt, I. Gery, E.J. Ballintine, and W.B. Wacker Cellular immune responsiveness of uveitis patients to retinal S-antigen Am J Ophthalmol 89 2 1980 173 179
13. D.J. Wyler, H.J. Blackman, and M.N. Lunde Cellular hypersensitivity to toxoplasmal and retinal antigens in patients with toxoplasmal retinochoroiditis Am J Trop Med Hyg 29 6 1980 1181 1186
14. D.S. Gregerson, I.W. Abrahams, and C.E. Thirkill Serum antibody levels of uveitis patients to bovine retinal antigens Invest Ophthalmol Vis Sci 21 5 1981 669 680
15. I.W. Abrahams, and D.S. Gregerson Longitudinal study of serum antibody responses to retinal antigens in acute ocular toxoplasmosis Am J Ophthalmol 93 2 1982 224 231
16. I.W. Abrahams, and D.S. Gregerson Longitudinal study of serum antibody responses to bovine retinal S-antigen in endogenous granulomatous uveitis Br J Ophthalmol 67 10 1983 681 684
17. A. Kijlstra, R. Hoekzema, A. vd Lelij, G. Doekes, and A. Rothova Humoral and cellular immune reactions against retinal antigens in clinical disease Curr Eye Res 9 Suppl 1990 85 89
18. J.P. Faure Autoimmunity and the retina Curr Top Eye Res 2 1980 215 302
19. Y. de Kozak, J. Sakai, B. Thillaye, and J.P. Faure S antigen-induced experimental autoimmune uveo-retinitis in rats Curr Eye Res 1 6 1981 327 337
20. L.V. Rizzo, R.A. Morawetz, N.E. Miller-Rivero, R. Choi, B. Wiggert, and C.C. Chan IL-4 and IL-10 are both required for the induction of oral tolerance J Immunol 162 5 1999 2613 2622
21. J.P. Faure, and Y. Kozak Cellular and humoral reactions to retinal antigens; specific suppression of experimental uveoretinitis S. Helmsen Gery Nussenblatt Immunology of the eye, workshop 2: autoimmune phenomena and ocular disorders 1981 Information Retrieval Inc. New York 33 48
22. J.P. Faure, Y. de Kozak, S. Takano, and B. Thillaye Treatment of experimental uveoretinitis with retinal S antigen Y.U. Press Sears, new directions in ophthalmic research 1981 New Haven 31 45
23. M. Saari, I. Vuorre, H. Neiminen, and S. Raisanen Acquired toxoplasmic chorioretinitis Arch Ophthalmol 94 9 1976 1485 1488
24. Silveira C. Toxoplasmose: Dúvidas e controvérsias. Erechim, RS: EdiFAPES, 2002.
25. C. Dorey, J. Cozette, and J.P. Faure A simple and rapid method for isolation of retinal S antigen Ophthalmic Res 14 4 1982 249 255
26. A.P. Brezin, C.E. Egwuagu, M. Burnier Jr., C. Silveira, R.M. Mahdi, and R.T. Gazzinelli Identification of Toxoplasma gondii in paraffin-embedded sections by the polymerase chain reaction Am J Ophthalmol 110 6 1990 599 604
27. D.R. Pepperberg, T.L. Okajima, H. Ripps, G.J. Chader, and B. Wiggert Functional properties of interphotoreceptor retinoid-binding protein Photochem Photobiol 54 6 1991 1057 1060
28. D.R. Pepperberg, T.L. Okajima, B. Wiggert, H. Ripps, R.K. Crouch, and G.J. Chader Interphotoreceptor retinoid-binding protein (IRBP). Molecular biology and physiological role in the visual cycle of rhodopsin Mol Neurobiol 7 1 1993 61 85
29. D.S. Papermaster, and W.J. Dreyer Rhodopsin content in the outer segment membranes of bovine and frog retinal rods Biochemistry 13 11 1974 2438 2444
30. C. Correa-Sales, C.E. Tosta, and L.V. Rizzo The effects of anesthesia with thiopental on T lymphocyte responses to antigen and mitogens in vivo and in vitro Int J Immunopharmacol 19 2 1997 117 128
31. A.L. Vallochi, J.H. Yamamoto, D. Schlesinger, M.A. Machado, C. Silveira, and M.C. Martins Lack of evidence for superantigen activity of Toxoplasma gondii towards human T cells Braz J Med Biol Res 34 8 2001 1023 1031
32. R.M. Whittle, G.R. Wallace, R.A. Whiston, D.C. Dumonde, and M.R. Stanford Human antiretinal antibodies in toxoplasma retinochoroiditis Br J Ophthalmol 82 9 1998 1017 1021
33. E.J. Feron, V.N. Klaren, E.A. Wierenga, G.M. Verjans, and A. Kijlstra Characterization of Toxoplasma gondii-specific T cells recovered from vitreous fluid of patients with ocular toxoplasmosis Invest Ophthalmol Vis Sci 42 13 2001 3228 3232
34. C.C. Chan, R.B. Nussenblatt, M.K. Kim, A.G. Palestine, K. Awadzi, and E.A. Ottesen Immunopathology of ocular onchocerciasis. 2. Anti-retinal autoantibodies in serum and ocular fluids Ophthalmology 94 4 1987 439 443
35. N.M. McKechnie, G. Braun, V. Connor, S. Klager, D.W. Taylor, and R.A. Alexander Immunologic cross-reactivity in the pathogenesis of ocular onchocerciasis Invest Ophthalmol Vis Sci 34 10 1993 2888 2902
36. G. Moalem, R. Leibowitz-Amit, E. Yoles, F. Mor, I.R. Cohen, and M. Schwartz Autoimmune T cells protect neurons from secondary degeneration after central nervous system axotomy Nat Med 5 1 1999 49 55
37. P. Kalinski, P.L. Vieira, J.H. Schuitemaker, E.C. de Jong, and M.L. Kapsenberg Prostaglandin E(2) is a selective inducer of interleukin-12 p40 (IL-12p40) production and an inhibitor of bioactive IL-12p70 heterodimer Blood 97 11 2001 3466 3469
38. J. Kipnis, T. Mizrahi, E. Hauben, I. Shaked, E. Shevach, and M. Schwartz Neuroprotective autoimmunity: naturally occurring CD4+CD25+ regulatory T cells suppress the ability to withstand injury to the central nervous system Proc Natl Acad Sci U S A 99 24 2002 15620 15625
39. J. Kipnis, T. Mizrahi, E. Yoles, A. Ben-Nun, M. Schwartz, and A. Ben-Nur Myelin specific Th1 cells are necessary for post-traumatic protective autoimmunity J Neuroimmunol 130 1-2 2002 78 85
40. T. Mizrahi, E. Hauben, and M. Schwartz The tissue-specific self-pathogen is the protective self-antigen: the case of uveitis J Immunol 169 10 2002 5971 5977
41. R. Barouch, and M. Schwartz Autoreactive T cells induce neurotrophin production by immune and neural cells in injured rat optic nerve: implications for protective autoimmunity FASEB J 16 10 2002 1304 1306
42. E. Kwidzinski, L.K. Mutlu, A.D. Kovac, J. Bunse, J. Goldmann, and J. Mahlo Self-tolerance in the immune privileged CNS: lessons from the entorhinal cortex lesion model J Neural Transm 65 Suppl 2003 29 49