Probing coupled motions in enzymatic hydrogen tunnelling reactions

Biochemical Society Transactions

Volumn 37, Issue 2, 2009, Pages 349-353

  Allemann, Rudolf K ^a   Evans, Rhiannon M ^a   Loveridge, E Joel ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Dihydrofolate reductase (DHFR); Hydrogen tunnelling reaction; Protein dynamics; Protein coupled motion; Quantum mechanical tunnelling; Thermotoga maritima

Indexed keywords

DIHYDROFOLATE REDUCTASE; GLYCEROL; HYDROGEN; METHANOL;

ANALYTIC METHOD; CATALYSIS; DIMERIZATION; ENZYMATIC HYDROGEN TUNNELLING REACTION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME KINETICS; ENZYME MECHANISM; ENZYME STRUCTURE; ENZYME SUBSTRATE; GENE MUTATION; GENE REARRANGEMENT; HYDROPHILICITY; MOLECULAR PROBE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; REVIEW; TEMPERATURE DEPENDENCE; THERMOSTABILITY; VISCOMETRY; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; METABOLISM; PROTEIN CONFORMATION; QUANTUM THEORY; THERMOTOGA MARITIMA;

THERMOTOGA MARITIMA;

CATALYSIS; HYDROGEN; MODELS, MOLECULAR; PROTEIN CONFORMATION; QUANTUM THEORY; TETRAHYDROFOLATE DEHYDROGENASE; THERMOTOGA MARITIMA;

EID: 65549106864     PISSN: 03005127     EISSN: 14708752     Source Type: Journal    
DOI: 10.1042/BST0370349     Document Type: Review

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