Human DNA polymerase mu (Pol μ) exhibits an unusual replication slippage ability at AAF lesion

Nucleic Acids Research

Volumn 30, Issue 9, 2002, Pages 2061-2067

  Duvauchelle, Jean Baptiste ^a   Blanco, Luis ^b   Fuchs, Robert P P ^a   Cordonnier, Agnes M ^a  

^a ESBS   (France)

^b UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CELL EXTRACT; DEOXYGUANOSINE PHOSPHATE; DNA POLYMERASE; N (2 FLUORENYL)ACETAMIDE; SINGLE STRANDED DNA;

ARTICLE; BASE PAIRING; CONTROLLED STUDY; DNA ADDUCT; DNA REPLICATION; DNA SEQUENCE; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVITY; FIBROBLAST; HELA CELL; HUMAN; HUMAN CELL; ISOTOPE LABELING; PRIORITY JOURNAL;

2-ACETYLAMINOFLUORENE; ANTIBODIES; BASE SEQUENCE; CARCINOGENS; CELL EXTRACTS; CELL LINE, TRANSFORMED; CELLS, CULTURED; DEOXYGUANINE NUCLEOTIDES; DEOXYRIBONUCLEOTIDES; DNA ADDUCTS; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; HELA CELLS; HUMANS; MODELS, GENETIC; RNA, MESSENGER;

EID: 0036567155     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Two novel human and mouse DNA polymerases of the polX family
2. DNA polymerase mu (Pol mu), homologous to TdT, could act as a DNA mutator in eukaryotic cells
3. DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis
4. Identification of an intrinsic 5′-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda. A possible role in base excision repair
5. A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins
6. From BRCAI to RAP1: A widespread BRCT module closely associated with DNA repair
7. DNA polymerase mu, a candidate hypermutase?
8. The translesion DNA polymerase zeta plays a major role in Ig and bcl-6 somatic hypermutation
9. Somatic mutation hotspots correlate with DNA polymerase eta error spectrum
10. DNA polymerase eta is an A-T mutator in somatic hypermutation of immunoglobulin variable genes
11. Altered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template
12. Eukaryotic DNA polymerases: Proposal for a revised nomenclature
13. Highly frequent frameshift DNA synthesis by human DNA polymerase mu
14. DNA double-strand breaks: Signaling, repair and the cancer connection
15. Mre11 and Ku70 interact in somatic cells, but are differentially expressed in early meiosis
16. Association of terminal deoxynucleotidyl transferase with Ku
17. The role of DNA polymerase activity in human non-homologous endjoining
18. Efficient processing of DNA ends during yeast nonhomologous end joining. Evidence for a DNA polymerase beta (Po14)-dependent pathway
19. Impaired translesion synthesis in xeroderma pigmentosum variant extracts
20. Domain structure, localization and function of DNA polymerase eta, defective in xeroderma pigmentosum variant cells
21. Xeroderma pigmentosum variant: Generation and characterization of fibroblastic cell lines transformed with SV40 large T antigen
22. New strategy for the construction of single-stranded plasmids with single mutagenic lesions
23. A new mathematical model for relative quantification in real-time RT-PCR
24. hRAD30 mutations in the variant form of xeroderma pigmentosum
25. The XPV (xeroderma pigmentosum variant) gene encodes human DNA polymerase eta
26. Mechanisms of frameshift mutations: Insight from aromatic amines
27. Modulation of terminal deoxynucleotidyltransferase activity by the DNA-dependent protein kinase