SCOPUS 정보 검색 플랫폼

Journal of Computer-Aided Molecular Design

Volumn 23, Issue 5, 2009, Pages 273-288

Identifying conformational changes of the β2 adrenoceptor that enable accurate prediction of ligand/receptor interactions and screening for GPCR modulators

(3) Reynolds, Kimberly A a Katritch, Vsevolod b Abagyan, Ruben a

a SCRIPPS RESEARCH INSTITUTE (United States)

b MOLSOFT LLC (United States)

Author keywords

Agonist; G protein coupled receptor; GPCR; Homology model; MMFF; Virtual ligand screening; 2 Adrenoceptor

Indexed keywords

LIGANDS;

ACCURATE PREDICTION; AGONIST; CONFORMATIONAL CHANGE; G PROTEIN COUPLED RECEPTORS; GPCR; HOMOLOGY MODELING; LIGAND-RECEPTOR INTERACTIONS; MMFF; VIRTUAL LIGAND SCREENING; Β2 ADRENOCEPTOR;

CONFORMATIONS;

2 AMINO 6,7 DIHYDROXYTETRALIN; BETA 2 ADRENERGIC RECEPTOR; BUPRANOLOL; CARAZOLOL; CARTEOLOL; CARVEDILOL; DOBUTAMINE; DOPEXAMINE; FENOTEROL; FORMOTEROL; G PROTEIN COUPLED RECEPTOR; LABETALOL; NORADRENALIN; OXPRENOLOL; PINDOLOL; PIRBUTEROL; PROPRANOLOL; PROXODOLOL; RHODOPSIN; SALBUTAMOL; TIMOLOL;

AMINO ACID SEQUENCE; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DRUG STRUCTURE; LIGAND BINDING; MOLECULAR DOCKING; PREDICTION; PRIORITY JOURNAL; RECEPTOR BINDING;

EID: 65049089399 PISSN: 0920654X EISSN: 15734951 Source Type: Journal
DOI: 10.1007/s10822-008-9257-9 Document Type: Article

Times cited : (58)

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