Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8

Journal of Lipid Research

Volumn 50, Issue 2, 2009, Pages 293-300

  Tang, Weiqing ^a,b   Ma, Yinyan ^b   Jia, Lin ^b   Ioannou, Yiannis A ^c   Davies, Joanna P ^c   Yu, Liqing ^b  

^a PEKING UNIVERSITY   (China)

^b WAKE FOREST SCHOOL OF MEDICINE   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

ATP binding cassette; Niemann Pick C1 Like 1; Phytosterols; Sterol absorption

Indexed keywords

ABC TRANSPORTER G5; ABC TRANSPORTER G8; CHOLESTEROL; LIPID; MEMBRANE PROTEIN; NIEMANN PICK C1 LIKE 1 PROTEIN; PHYTOSTEROL; UNCLASSIFIED DRUG; ABC TRANSPORTER; ABCG5 PROTEIN, MOUSE; ABCG8 PROTEIN, MOUSE; CARRIER PROTEIN; LIPOPROTEIN; NPC1L1 PROTEIN, MOUSE; SITOSTEROL DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; GENE INACTIVATION; GENETIC DISORDER; INTESTINE ABSORPTION; LIPID ANALYSIS; LIVER; MALE; MOUSE; NONHUMAN; PLASMA; PRIORITY JOURNAL; PROTECTION; PROTEIN FUNCTION; SITOSTEROLEMIA; TISSUE HOMOGENATE; WESTERN BLOTTING; ANIMAL; BLOOD; GENETICS; METABOLISM; MOUSE MUTANT; TRANSGENIC MOUSE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CHOLESTEROL; LIPOPROTEINS; LIVER; MALE; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; PHYTOSTEROLS; SITOSTEROLS;

EID: 64749088618     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M800439-JLR200     Document Type: Article

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