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Volumn 320, Issue 2, 2007, Pages 559-564

Niemann-pick C1-like 1 overexpression facilitates ezetimibe-sensitive cholesterol and β-sitosterol uptake in CaCo-2 cells

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; EZETIMIBE; MEMBRANE PROTEIN; PHOSPHATIDYLCHOLINE; PROTEIN NPC1L1; SITOSTEROL; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

EID: 33846421597     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.106.114181     Document Type: Article
Times cited : (107)

References (19)
  • 3
    • 16844376244 scopus 로고    scopus 로고
    • Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia
    • Davies JP, Scott C, Oishi K, Liapis A, and Ioannou YA (2005) Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia. J Biol Chem 280:12710-12720.
    • (2005) J Biol Chem , vol.280 , pp. 12710-12720
    • Davies, J.P.1    Scott, C.2    Oishi, K.3    Liapis, A.4    Ioannou, Y.A.5
  • 4
    • 4043124013 scopus 로고    scopus 로고
    • Niemann-Pick C1 like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis
    • Davis HR Jr, Zhu LJ, Hoos LM, Tetzloff G, Maguire M, Liu J, Yao X, Iyer SP, Lam MH, Lund EG, et al. (2004) Niemann-Pick C1 like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis. J Biol Chem 279:33586-33592.
    • (2004) J Biol Chem , vol.279 , pp. 33586-33592
    • Davis Jr, H.R.1    Zhu, L.J.2    Hoos, L.M.3    Tetzloff, G.4    Maguire, M.5    Liu, J.6    Yao, X.7    Iyer, S.P.8    Lam, M.H.9    Lund, E.G.10
  • 6
    • 11244300911 scopus 로고    scopus 로고
    • Interaction of cholesterol with sphingosine: Physicochemical characterization and impact on intestinal absorption
    • Garmy N, Taieb N, Yahi N, and Fantini J (2005) Interaction of cholesterol with sphingosine: physicochemical characterization and impact on intestinal absorption. J Lipid Res 46:36-45.
    • (2005) J Lipid Res , vol.46 , pp. 36-45
    • Garmy, N.1    Taieb, N.2    Yahi, N.3    Fantini, J.4
  • 7
    • 0035292910 scopus 로고    scopus 로고
    • Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract
    • Horter D and Dressman JB (2001) Influence of physicochemical properties on dissolution of drugs in the gastrointestinal tract. Adv Drug Deliv Rev 46:75-87.
    • (2001) Adv Drug Deliv Rev , vol.46 , pp. 75-87
    • Horter, D.1    Dressman, J.B.2
  • 8
    • 15944399444 scopus 로고    scopus 로고
    • Molecular mechanisms of cholesterol absorption and transport in the intestine
    • Hui DY and Howles PN (2005) Molecular mechanisms of cholesterol absorption and transport in the intestine. Semin Cell Dev Biol 16:183-192.
    • (2005) Semin Cell Dev Biol , vol.16 , pp. 183-192
    • Hui, D.Y.1    Howles, P.N.2
  • 12
    • 0021126684 scopus 로고
    • The effect of phosphoglycerides on the incorporation of cholesterol into isolated brush-border membranes from rabbit small intestine
    • Proulx P, Aubry H, Brglez I, and Williamson DG (1984) The effect of phosphoglycerides on the incorporation of cholesterol into isolated brush-border membranes from rabbit small intestine. Biochim Biophys Acta 775:341-346.
    • (1984) Biochim Biophys Acta , vol.775 , pp. 341-346
    • Proulx, P.1    Aubry, H.2    Brglez, I.3    Williamson, D.G.4
  • 15
    • 0035831089 scopus 로고    scopus 로고
    • The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys
    • van Heek M, Compton DS, and Davis HR (2001) The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys. Eur J Pharmacol 415:79-84.
    • (2001) Eur J Pharmacol , vol.415 , pp. 79-84
    • van Heek, M.1    Compton, D.S.2    Davis, H.R.3
  • 16
    • 21244465525 scopus 로고    scopus 로고
    • Cholesterol and plant sterol absorption: Recent insights
    • von Bergmann K, Sudhop T, and Lutjohann D (2005) Cholesterol and plant sterol absorption: recent insights. Am J Cardiol 96:10D-14D.
    • (2005) Am J Cardiol , vol.96
    • von Bergmann, K.1    Sudhop, T.2    Lutjohann, D.3
  • 17
    • 14244262377 scopus 로고    scopus 로고
    • Compound heterozygosity for two non-synonymous polymorphisms in NPC1L1 in a non-responder to ezetimibe
    • Wang J, Williams CM, and Hegele RA (2005) Compound heterozygosity for two non-synonymous polymorphisms in NPC1L1 in a non-responder to ezetimibe. Clin Genet 67:175-177.
    • (2005) Clin Genet , vol.67 , pp. 175-177
    • Wang, J.1    Williams, C.M.2    Hegele, R.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.