Redox effector factor-1, combined with reactive oxygen species, plays an important role in the transformation of JB6 cells

Carcinogenesis

Volumn 28, Issue 11, 2007, Pages 2382-2390

  Yang, Sun ^a   Misner, Bobbye J ^a   Chiu, Rita J ^a   Meyskens Jr , Frank L ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; CADMIUM CHLORIDE; DNA BASE; HYDROGEN PEROXIDE; LIPOCORTIN 5; PHORBOL 13 ACETATE 12 MYRISTATE; REACTIVE OXYGEN METABOLITE; REDOX EFFECTOR FACTOR 1; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR AP 1;

ANIMAL CELL; ARTICLE; CELL COUNT; CELL PROTECTION; CELL STRESS; CELL TRANSFORMATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DNA DAMAGE; DNA REPAIR; EPIDERMIS CELL; EXCISION REPAIR; GENE ACTIVATION; GENETIC TRANSCRIPTION; MALIGNANT NEOPLASTIC DISEASE; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; OXIDATION REDUCTION REACTION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; TUMOR GROWTH; ULTRAVIOLET B RADIATION;

ANIMALS; ANNEXIN A5; APOPTOSIS; BASE SEQUENCE; CADMIUM CHLORIDE; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; DNA DAMAGE; DNA-(APURINIC OR APYRIMIDINIC SITE) LYASE; HYDROGEN PEROXIDE; MICE; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RNA, SMALL INTERFERING; TETRADECANOYLPHORBOL ACETATE; TRANSCRIPTION FACTOR AP-1; ULTRAVIOLET RAYS;

EID: 36148930625     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgm128     Document Type: Article

References (52)

1. Angel,J.M. et al. (1999) Genetics of skin tumor promotion. Prog. Exp. Tumor Res., 35, 143-157.
2. Marnett,L.J. et al. (1994) Modulation of oxidant formation in mouse skin in vivo by tumor-promoting phorbol esters. Cancer Res., 54, 1886s-1889s.
3. Mueller,M.M. (2006) Inflammation in epithelial skin tumours: Old stories and new ideas. Eur. J. Cancer, 42, 735-744.
4. Nakamura,Y. et al. (1998) Suppression of tumor promoter-induced oxidative stress and inflammatory responses in mouse skin by a superoxide generation inhibitor 1′-acetoxychavicol acetate. Cancer Res., 58, 4832-4839.
5. Slaga,T.J. (1995) Inhibition of skin tumor initiation, promotion, and progression by antioxidants and related compounds. Crit Rev. Food Sci. Nutr., 35, 51-57.
6. Dong,Z. (2000) Effects of food factors on signal transduction pathways. Biofactors, 12, 17-28.
7. Li,J.J. et al. (1997) Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response. Cancer Res., 57, 3569-3576.
8. Ding,M. et al. (2004) Inhibition of AP-1 and neoplastic transformation by fresh apple peel extract. J. Biol. Chem., 279 10670-10676.
9. Dreher,D. et al. (1996) Role of oxygen free radicals in cancer development. Eur. J. Cancer, 32A, 30-38.
10. Bode,A.M. et al. (2004) Targeting signal transduction pathways by chemopreventive agents. Mutat. Res., 555, 33-51.
11. Colburn,N.H. et al. (1981) Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion. Proc. Natl Acad. Sci. USA, 78, 6912-6916.
12. Bernstein,L.R. et al. (1989) AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science, 244, 566-569.
13. Huang,C. et al. (1998) Shortage of mitogen-activated protein kinase is responsible for resistance to AP-1 transactivation and transformation in mouse JB6 cells. Proc. Natl Acad. Sci. USA, 95, 156-161.
14. Evans,A.R. et al. (2000) Going APE over ref-1. Mutat. Res., 461, 83-108.
15. Yang,S. et al. (2005) Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (APE/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an APE/Ref-1 inhibitor. Mol. Cancer Ther., 4, 1923-1935.
16. 2 induces translocation of APE/Ref-1 to mitochondria in the Raji B-cell line. J. Cell. Physiol., 193 180-186.
17. Ramana,C.V. et al. (1998) Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals. Proc. Natl Acad. Sci. USA, 95, 5061-5066.
18. Grosch,S. et al. (1998) Apurinic endonuclease (Ref-1) is induced in mammalian cells by oxidative stress and involved in clastogenic adaptation. Cancer Res., 58, 4410-4416.
19. Stuart,J.A. et al. (2004) DNA base excision repair activities and pathway function in mitochondrial and cellular lysates from cells lacking mitochondrial DNA. Nucleic Acids Res., 32, 2181-2192.
20. Singh,K.K. et al. (2005) Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis. Gene, 354, 140-146.
21. Kelley,M.R. et al. (2001) Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1. Antioxid. Redox Signal., 3, 671-683.
22. Walker,L.J. et al. (1993) Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding. Mol. Cell. Biol., 13, 5370-5376.
23. Wang,D. et al. (2004) Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: Enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition. Mol. Cancer Ther., 3, 679-686.
24. Lam,W. et al. (2006) Apurinic/apyrimidinic endonuclease-1 protein level is associated with the cytotoxicity of L-configuration deoxycytidine analogs (troxacitabine and beta-L-2′,3′- dideoxy-2′,3′-didehydro-5-fluorocytidine) but not D-configuration deoxycytidine analogs (gemcitabine and beta-D-arabinofuranosylcytosine). Mol. Pharmacol., 69, 1607-1614.
25. Yang,S. et al. (2004) During human melanoma progression AP-1 binding pairs are altered with loss of c-Jun in vitro. Pigment Cell Res., 17, 74-83.
26. Struthers,L. et al. (1998) Direct detection of 8 oxodeoxyguanosine and 8-oxoguanine by avidin and its analogues. Anal. Biochem., 255, 20-31.
27. McEligot,A.J. et al. (2005) Redox regulation by intrinsic species and extrinsic nutrients in normal and cancer cells. Annu. Rev. Nutr. 25, 261-295.
28. Moore,D.H. et al. (2000) Alterations in the expression of the DNA repair/redox enzyme APE/ref-1 in epithelial ovarian cancers. Clin. Cancer Res., 6, 602-609.
29. Tanner,B. et al. (2004) Nuclear expression of apurinic/ apyrimidinic endonuclease increases with progression of ovarian carcinomas. Gynecol. Oncol., 92, 568-577.
30. Lau,J.P. et al. (2004) Effects of gemcitabine on APE/ref-1 endonuclease activity in pancreatic cancer cells, and the therapeutic potential of antisense oligonucleotides. Br. J. Cancer, 91, 1166-1173.
31. Nishigori,C. et al. (2004) Role of reactive oxygen species in skin carcinogenesis. Antioxid. Redox Signal., 6, 561-570.
32. Waisberg,M. et al. (2003) Molecular and cellular mechanisms of cadmium carcinogenesis. Toxicology, 192, 95-117.
33. Riley,P.A. (1994) Free radicals in biology: Oxidative stress and the effects of ionizing radiation. Int. J. Radiat. Biol., 65, 27-33.
34. Hsiao,C.J. et al. (2004) Characterization of Cd-induced molecular events prior to cellular damage in primary rat hepatocytes in culture: activation of the stress activated signal protein JNK and transcription factor AP-1. J. Biochem. Mol. Toxicol., 18, 133-142.
35. Souza,V. et al. (2004) Zinc pretreatment prevents hepatic stellate cells from cadmium-produced oxidative damage. Cell Biol. Toxicol., 20, 241-251.
36. Cooper,S. et al. (2005) Differential inhibition of UVB-induced AP-1 and NF-kappaB transactivation by components of the jun bZIP domain. Mol. Carcinog., 43, 108-116.
37. Bowden,G.T. (2004) Prevention of non-melanoma skin cancer by targeting ultraviolet-B-light signalling. Nat. Rev. Cancer, 4, 23-35.
38. Tanos,T. et al. (2005) Phosphorylation of c-Fos by members of the p38 MAPK family. Role in the AP-1 response to UV light. J. Biol. Chem., 280, 18842-18852.
39. Rahman,I. et al. (2002) Oxidative stress and TNF-alpha induce histone acetylation and NF-kappaB/AP-1 activation in alveolar epithelial cells: Potential mechanism in gene transcription in lung inflammation. Mol. Cell. Biochem., 234-235, 239-248.
40. Chang,H. et al. (2003) The role of H2O2 as a mediator of UVB-induced apoptosis in keratinocytes. Free Radic. Res., 37 655-663.
41. Mantena,S.K. et al. (2006) Grape seed proanthocyanidins inhibit UV-radiation-induced oxidative stress and activation of MAPK and NF-kappaB signaling in human epidermal keratinocytes. Free Radic. Biol. Med., 40, 1603-1614.
42. Kim,G.J. et al. (2006) Mitochondrial dysfunction, persistently elevated levels of reactive oxygen species and radiation-induced genomic instability: A review. Mutagenesis, 21, 361-367.
43. Farmer,P.J. et al. (2003) Melanin as a target for melanoma chemotherapy: Pro-oxidant effect of oxygen and metals on melanoma viability. Pigment Cell Res., 16, 273-279.
44. Hsu,T.C. et al. (2001) Transformation nonresponsive cells owe their resistance to lack of p65/nuclear factor-kappaB activation. Cancer Res., 61, 4160-4168.
45. Zhao,Q. et al. (2005) 2-Arachidonoylglycerol stimulates activator protein-1-dependent transcriptional activity and enhances epidermal growth factor-induced cell transformation in JB6 P+ cells. J. Biol. Chem., 280, 26735-26742.
46. Huang,C. et al. (1999) JNK activation is required for JB6 cell transformation induced by tumor necrosis factor-alpha but not by 12-O-tetradecanoyl-phorbol-13-acetate. J. Biol. Chem., 274, 29672-29676.
47. Tatsumi,Y. et al. (2006) Involvement of the paxillin pathway in JB6 C141 cell transformation. Cancer Res., 66, 5968-5974.
48. Meyskens,F.L. Jr et al. (2001) Aberrant redox regulation in human metastatic melanoma cells compared to normal melanocytes. Free Radic. Biol. Med., 31, 799-808.
49. Grandemange,S. et al. (2005) Stimulation of mitochondrial activity by p43 overexpression induces human dermal fibroblast transformation. Cancer Res., 65, 4282-4291.
50. Radisky,D.C. et al. (2005) Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability. Nature, 436 123-127.
51. Behrend,L. et al. (2003) Reactive oxygen species in oncogenic transformation. Biochem. Soc. Trans., 31, 1441-1444.
52. Nishigori,C. (2006) Cellular aspects of photocarcinogenesis. Photochem. Photobiol. Sci., 5, 208-214.