Conserved rhodopsin intradiscal structural motifs mediate stabilization: Effects of zinc

Biochemistry

Volumn 48, Issue 8, 2009, Pages 1793-1800

  Gleim, Scott ^a   Stojanovic, Aleksandar ^a   Arehart, Eric ^a   Byington, Daniel ^a   Hwa, John ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC EFFECTS; ALZHEIMER DISEASE; DIVALENT CATIONS; DIVERSE RANGES; DOSE DEPENDENTS; HOMEOSTATIC REGULATIONS; LOOP REGIONS; MISFOLDING; NEURODEGENERATIVE DISORDERS; OUTER SEGMENTS; PRION DISEASE; PROTEIN INSTABILITIES; RETINAL DEGENERATIONS; RETINITIS PIGMENTOSA; SINGLE-POINT MUTATIONS; SITE-DIRECTED MUTAGENESIS; STRUCTURAL MOTIFS; TRACE METAL CONCENTRATIONS; WILD TYPES; ZINC-BINDING DOMAINS;

CELL DEATH; ENZYME ACTIVITY; PINCH EFFECT; TRACE ELEMENTS;

ZINC;

EDETIC ACID; RHODOPSIN; TRACE METAL; ZINC; ZINC BINDING PROTEIN;

ARTICLE; CELL DEATH; CHELATION; ENZYME REGULATION; GENE CLUSTER; GENE MUTATION; HEMOSTASIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN MOTIF; PROTEIN STABILITY; PROTEIN STRUCTURE; RETINA ROD OUTER SEGMENT; RETINITIS PIGMENTOSA; SITE DIRECTED MUTAGENESIS; WILD TYPE;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CHELATING AGENTS; CONSERVED SEQUENCE; CRYSTALLOGRAPHY, X-RAY; HISTIDINE; HUMANS; HYDROGEN BONDING; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; OPSINS; PROTEIN STABILITY; RETINITIS PIGMENTOSA; RHODOPSIN; SEQUENCE ANALYSIS, PROTEIN; TEMPERATURE; TIME FACTORS; ZINC;

EID: 64349094023     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi800968w     Document Type: Article

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