-
1
-
-
0015363173
-
The cellular production of hydrogen peroxide
-
Boveris A, Oshino N, Chance B (1972) The cellular production of hydrogen peroxide. Biochem J 128: 617-630.
-
(1972)
Biochem J
, vol.128
, pp. 617-630
-
-
Boveris, A.1
Oshino, N.2
Chance, B.3
-
2
-
-
0018776894
-
Hydroperoxide metabolism in mammalian organs
-
Chance B, Sies H, Boveris A (1979) Hydroperoxide metabolism in mammalian organs. Physiol Rev 59: 527-605.
-
(1979)
Physiol Rev
, vol.59
, pp. 527-605
-
-
Chance, B.1
Sies, H.2
Boveris, A.3
-
3
-
-
0000466588
-
Respiratory chain linked H(2)O(2) production in pigeon heart mitochondria
-
Loschen G, Flohe L, Chance B (1971) Respiratory chain linked H(2)O(2) production in pigeon heart mitochondria. FEBS Lett 18: 261-264.
-
(1971)
FEBS Lett
, vol.18
, pp. 261-264
-
-
Loschen, G.1
Flohe, L.2
Chance, B.3
-
4
-
-
0034306267
-
Mitochondria, oxygen free radicals, disease and ageing
-
Raha S, Robinson BH (2000) Mitochondria, oxygen free radicals, disease and ageing. Trends Biochem Sci 25: 222-230.
-
(2000)
Trends Biochem Sci
, vol.25
, pp. 222-230
-
-
Raha, S.1
Robinson, B.H.2
-
5
-
-
0031916984
-
The free radical theory of aging matures
-
Beckman KB, Ames BN (1998) The free radical theory of aging matures. Physiological Reviews 78: 547-581.
-
(1998)
Physiological Reviews
, vol.78
, pp. 547-581
-
-
Beckman, K.B.1
Ames, B.N.2
-
6
-
-
10344261154
-
Mitochondrial superoxide and aging: Uncoupling-protein activity and superoxide production
-
Brand MD, Buckingham JA, Esteves TC, Green K, Lambert AJ, et al. (2004) Mitochondrial superoxide and aging: uncoupling-protein activity and superoxide production. Biochemical Society Symposia 71: 203-213.
-
(2004)
Biochemical Society Symposia
, vol.71
, pp. 203-213
-
-
Brand, M.D.1
Buckingham, J.A.2
Esteves, T.C.3
Green, K.4
Lambert, A.J.5
-
8
-
-
0034643340
-
Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage
-
Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, et al. (2000) Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage. Nature 404: 787-790.
-
(2000)
Nature
, vol.404
, pp. 787-790
-
-
Nishikawa, T.1
Edelstein, D.2
Du, X.L.3
Yamagishi, S.4
Matsumura, T.5
-
9
-
-
0034710891
-
Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation
-
Du XL, Edelstein D, Rossetti L, Fantus IG, Goldberg H, et al. (2000) Hyperglycemia-induced mitochondrial superoxide overproduction activates the hexosamine pathway and induces plasminogen activator inhibitor-1 expression by increasing Sp1 glycosylation. Proceedings of the National Academy of Sciences of the United States of America 97: 12222-12226.
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, pp. 12222-12226
-
-
Du, X.L.1
Edelstein, D.2
Rossetti, L.3
Fantus, I.G.4
Goldberg, H.5
-
10
-
-
0344012015
-
Hyperglycemia increases mitochondrial superoxide in retina and retinal cells
-
Du Y, Miller CM, Kern TS (2003) Hyperglycemia increases mitochondrial superoxide in retina and retinal cells. Free Radical Biology & Medicine 35: 1491-1499.
-
(2003)
Free Radical Biology & Medicine
, vol.35
, pp. 1491-1499
-
-
Du, Y.1
Miller, C.M.2
Kern, T.S.3
-
11
-
-
0141755317
-
Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: Potential role in diabetic nephropathy
-
Kiritoshi S, Nishikawa T, Sonoda K, Kukidome D, Senokuchi T, et al. (2003) Reactive oxygen species from mitochondria induce cyclooxygenase-2 gene expression in human mesangial cells: potential role in diabetic nephropathy. Diabetes 52: 2570-2577.
-
(2003)
Diabetes
, vol.52
, pp. 2570-2577
-
-
Kiritoshi, S.1
Nishikawa, T.2
Sonoda, K.3
Kukidome, D.4
Senokuchi, T.5
-
12
-
-
2342563763
-
Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes
-
Ye G, Metreveli NS, Donthi RV, Xia S, Xu M, et al. (2004) Catalase protects cardiomyocyte function in models of type 1 and type 2 diabetes. Diabetes 53: 1336-1343.
-
(2004)
Diabetes
, vol.53
, pp. 1336-1343
-
-
Ye, G.1
Metreveli, N.S.2
Donthi, R.V.3
Xia, S.4
Xu, M.5
-
13
-
-
0037245335
-
Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation
-
Coppey LJ, Gellett JS, Davidson EP, Yorek MA (2003) Preventing superoxide formation in epineurial arterioles of the sciatic nerve from diabetic rats restores endothelium-dependent vasodilation. Free Radical Research 37: 33-40.
-
(2003)
Free Radical Research
, vol.37
, pp. 33-40
-
-
Coppey, L.J.1
Gellett, J.S.2
Davidson, E.P.3
Yorek, M.A.4
-
14
-
-
2542593338
-
Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes
-
Schrauwen P, Hesselink MKC (2004) Oxidative capacity, lipotoxicity, and mitochondrial damage in type 2 diabetes. Diabetes 53: 1412-1417.
-
(2004)
Diabetes
, vol.53
, pp. 1412-1417
-
-
Schrauwen, P.1
Hesselink, M.K.C.2
-
15
-
-
0035816639
-
Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A
-
Yamagishi SI, Edelstein D, Du XL, Kaneda Y, Guzman M, et al. (2001) Leptin induces mitochondrial superoxide production and monocyte chemoattractant protein-1 expression in aortic endothelial cells by increasing fatty acid oxidation via protein kinase A. Journal of Biological Chemistry 276: 25096-25100.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 25096-25100
-
-
Yamagishi, S.I.1
Edelstein, D.2
Du, X.L.3
Kaneda, Y.4
Guzman, M.5
-
16
-
-
0842328003
-
Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes
-
Green K, Brand MD, Murphy MP (2004) Prevention of mitochondrial oxidative damage as a therapeutic strategy in diabetes. Diabetes 53: S110-118.
-
(2004)
Diabetes
, vol.53
-
-
Green, K.1
Brand, M.D.2
Murphy, M.P.3
-
17
-
-
0035460705
-
Development of lipophilic cations as therapies for disorders due to mitochondrial dysfunction
-
Murphy MP (2001) Development of lipophilic cations as therapies for disorders due to mitochondrial dysfunction. Expert Opinion on Biological Therapy 1: 753-764.
-
(2001)
Expert Opinion on Biological Therapy
, vol.1
, pp. 753-764
-
-
Murphy, M.P.1
-
18
-
-
10644249072
-
Investigating mitochondrial radical production using targeted probes
-
Murphy MP (2004) Investigating mitochondrial radical production using targeted probes. Biochemical Society Transactions 32: 1011-1014.
-
(2004)
Biochemical Society Transactions
, vol.32
, pp. 1011-1014
-
-
Murphy, M.P.1
-
19
-
-
34250664327
-
MitoQ-a mitochondria-targeted antioxidant
-
Tauskela JS (2007) MitoQ-a mitochondria-targeted antioxidant. IDrugs 10: 399-412.
-
(2007)
IDrugs
, vol.10
, pp. 399-412
-
-
Tauskela, J.S.1
-
20
-
-
33845969219
-
Reactive oxygen and targeted antioxidant administration in endothelial cell mitochondria
-
O'Malley Y, Fink BD, Ross NC, Prisinzano TE, Sivitz WI (2006) Reactive oxygen and targeted antioxidant administration in endothelial cell mitochondria. J Biol Chem 281: 39766-39775.
-
(2006)
J Biol Chem
, vol.281
, pp. 39766-39775
-
-
O'Malley, Y.1
Fink, B.D.2
Ross, N.C.3
Prisinzano, T.E.4
Sivitz, W.I.5
-
21
-
-
35448968884
-
Mitochondrial redox cycling of mitoquinone leads to superoxide production and cellular apoptosis
-
Doughan AK, Dikalov SI (2007) Mitochondrial redox cycling of mitoquinone leads to superoxide production and cellular apoptosis. Antioxid Redox Signal 9: 1825-1836.
-
(2007)
Antioxid Redox Signal
, vol.9
, pp. 1825-1836
-
-
Doughan, A.K.1
Dikalov, S.I.2
-
22
-
-
4544354262
-
Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I)
-
Lambert AJ, Brand MD (2004) Inhibitors of the quinone-binding site allow rapid superoxide production from mitochondrial NADH:ubiquinone oxidoreductase (complex I). Journal of Biological Chemistry 279: 39414-39420.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 39414-39420
-
-
Lambert, A.J.1
Brand, M.D.2
-
23
-
-
0036326045
-
Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart
-
Young ME, Guthrie PH, Razeghi P, Leighton B, Abbasi S, et al. (2002) Impaired long-chain fatty acid oxidation and contractile dysfunction in the obese Zucker rat heart. Diabetes 51: 2587-2595.
-
(2002)
Diabetes
, vol.51
, pp. 2587-2595
-
-
Young, M.E.1
Guthrie, P.H.2
Razeghi, P.3
Leighton, B.4
Abbasi, S.5
-
24
-
-
34347352169
-
Diabetic cardiomyopathy revisited
-
Boudina S, Abel ED (2007) Diabetic cardiomyopathy revisited. Circulation 115: 3213-3223.
-
(2007)
Circulation
, vol.115
, pp. 3213-3223
-
-
Boudina, S.1
Abel, E.D.2
-
25
-
-
39749147110
-
Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes
-
Muoio DM, Newgard CB (2008) Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes. Nat Rev Mol Cell Biol 9: 193-205.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 193-205
-
-
Muoio, D.M.1
Newgard, C.B.2
-
26
-
-
3342989837
-
Fine-tuning the hydrophobicity of a mitochondria-targeted antioxidant
-
Asin-Cayuela J, Manas AR, James AM, Smith RA, Murphy MP (2004) Fine-tuning the hydrophobicity of a mitochondria-targeted antioxidant. FEBS Letters 571: 9-16.
-
(2004)
FEBS Letters
, vol.571
, pp. 9-16
-
-
Asin-Cayuela, J.1
Manas, A.R.2
James, A.M.3
Smith, R.A.4
Murphy, M.P.5
-
27
-
-
0035895888
-
Selective targeting of a redox-active ubiquinone to mitochondria within cells: Antioxidant and antiapoptotic properties
-
Kelso GF, Porteous CM, Coulter CV, Hughes G, Porteous WK, et al. (2001) Selective targeting of a redox-active ubiquinone to mitochondria within cells: antioxidant and antiapoptotic properties. Journal of Biological Chemistry 276: 4588-4596.
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 4588-4596
-
-
Kelso, G.F.1
Porteous, C.M.2
Coulter, C.V.3
Hughes, G.4
Porteous, W.K.5
-
28
-
-
0026471557
-
Endothelial cells express insulin-like growth factor-binding proteins 2 to 6
-
Moser DR, Lowe WL Jr, Dake BL, Booth BA, Boes M, et al. (1992) Endothelial cells express insulin-like growth factor-binding proteins 2 to 6. Molecular Endocrinology 6: 1805-1814.
-
(1992)
Molecular Endocrinology
, vol.6
, pp. 1805-1814
-
-
Moser, D.R.1
Lowe Jr, W.L.2
Dake, B.L.3
Booth, B.A.4
Boes, M.5
-
29
-
-
36048945921
-
The mitochondrial proton leak in obesity-resistant and obesity-prone mice
-
Fink BD, Herlein JA, Almind K, Cinti S, Kahn CR, et al. (2007) The mitochondrial proton leak in obesity-resistant and obesity-prone mice. Am J Physiol Regul Integr Comp Physiol 293: R1773-1780.
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.293
-
-
Fink, B.D.1
Herlein, J.A.2
Almind, K.3
Cinti, S.4
Kahn, C.R.5
-
30
-
-
0035117975
-
Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells
-
Hong Y, Fink BD, Dillon JS, Sivitz WI (2001) Effects of adenoviral overexpression of uncoupling protein-2 and -3 on mitochondrial respiration in insulinoma cells. Endocrinology 142: 249-256.
-
(2001)
Endocrinology
, vol.142
, pp. 249-256
-
-
Hong, Y.1
Fink, B.D.2
Dillon, J.S.3
Sivitz, W.I.4
-
31
-
-
0033969421
-
Uncoupling proteins 2 and 3: Potential regulators of mitochondrial energy metabolism
-
Boss O, Hagen T, Lowell BB (2000) Uncoupling proteins 2 and 3: potential regulators of mitochondrial energy metabolism. Diabetes 49: 143-156.
-
(2000)
Diabetes
, vol.49
, pp. 143-156
-
-
Boss, O.1
Hagen, T.2
Lowell, B.B.3
-
32
-
-
0037033039
-
Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants
-
Echtay KS, Murphy MP, Smith RA, Talbot DA, Brand MD (2002) Superoxide activates mitochondrial uncoupling protein 2 from the matrix side. Studies using targeted antioxidants. Journal of Biological Chemistry 277: 47129-47135.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 47129-47135
-
-
Echtay, K.S.1
Murphy, M.P.2
Smith, R.A.3
Talbot, D.A.4
Brand, M.D.5
-
33
-
-
3543030406
-
In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate
-
Jekabsons MB, Nicholls DG (2004) In situ respiration and bioenergetic status of mitochondria in primary cerebellar granule neuronal cultures exposed continuously to glutamate. J Biol Chem 279: 32989-33000.
-
(2004)
J Biol Chem
, vol.279
, pp. 32989-33000
-
-
Jekabsons, M.B.1
Nicholls, D.G.2
-
34
-
-
0033856957
-
Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity
-
O'Brien J, Wilson I, Orton T, Pognan F (2000) Investigation of the Alamar Blue (resazurin) fluorescent dye for the assessment of mammalian cell cytotoxicity. Eur J Biochem 267: 5421-5426.
-
(2000)
Eur J Biochem
, vol.267
, pp. 5421-5426
-
-
O'Brien, J.1
Wilson, I.2
Orton, T.3
Pognan, F.4
-
35
-
-
43049141441
-
Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport
-
Lambert AJ, Buckingham JA, Boysen HM, Brand MD (2008) Diphenyleneiodonium acutely inhibits reactive oxygen species production by mitochondrial complex I during reverse, but not forward electron transport. Biochim Biophys Acta 1777: 397-403.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 397-403
-
-
Lambert, A.J.1
Buckingham, J.A.2
Boysen, H.M.3
Brand, M.D.4
-
36
-
-
20044384225
-
A possible site of superoxide generation in the complex I segment of rat heart mitochondria
-
Ohnishi ST, Ohnishi T, Muranaka S, Fujita H, Kimura H, et al. (2005) A possible site of superoxide generation in the complex I segment of rat heart mitochondria. J Bioenerg Biomembr 37: 1-15.
-
(2005)
J Bioenerg Biomembr
, vol.37
, pp. 1-15
-
-
Ohnishi, S.T.1
Ohnishi, T.2
Muranaka, S.3
Fujita, H.4
Kimura, H.5
-
37
-
-
33746329868
-
Energy converting NADH:quinone oxidoreductase (complex I)
-
Brandt U (2006) Energy converting NADH:quinone oxidoreductase (complex I). Annu Rev Biochem 75: 69-92.
-
(2006)
Annu Rev Biochem
, vol.75
, pp. 69-92
-
-
Brandt, U.1
-
38
-
-
33847687662
-
Respiratory complex I: Mechanistic and structural insights provided by the crystal structure of the hydrophilic domain
-
Sazanov LA (2007) Respiratory complex I: mechanistic and structural insights provided by the crystal structure of the hydrophilic domain. Biochemistry 46: 2275-2288.
-
(2007)
Biochemistry
, vol.46
, pp. 2275-2288
-
-
Sazanov, L.A.1
-
39
-
-
20044384225
-
A possible site of superoxide generation in the complex I segment of rat heart mitochondria
-
Ohnishi STOT, Muranaka S, Fujita H, Kimura H, Uemura K, Yoshida KKU (2005) A possible site of superoxide generation in the complex I segment of rat heart mitochondria. J Bioenerg Biomembr. pp 1-15.
-
(2005)
J Bioenerg Biomembr
, pp. 1-15
-
-
Ohnishi, S.T.O.T.1
Muranaka, S.2
Fujita, H.3
Kimura, H.4
Uemura, K.5
Yoshida, K.K.U.6
-
40
-
-
0036319021
-
Generation of reactive oxygen species by the mitochondrial electron transport chain
-
Liu Y, Fiskum G, Schubert D (2002) Generation of reactive oxygen species by the mitochondrial electron transport chain. Journal of Neurochemistry 80: 780-787.
-
(2002)
Journal of Neurochemistry
, vol.80
, pp. 780-787
-
-
Liu, Y.1
Fiskum, G.2
Schubert, D.3
-
41
-
-
0034740585
-
DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria
-
Votyakova TV, Reynolds IJ (2001) DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria. Journal of Neurochemistry 79: 266-277.
-
(2001)
Journal of Neurochemistry
, vol.79
, pp. 266-277
-
-
Votyakova, T.V.1
Reynolds, I.J.2
-
43
-
-
3042841952
-
How free fatty acids inhibit glucose utilization in human skeletal muscle
-
Roden M (2004) How free fatty acids inhibit glucose utilization in human skeletal muscle. News Physiol Sci 19: 92-96.
-
(2004)
News Physiol Sci
, vol.19
, pp. 92-96
-
-
Roden, M.1
-
44
-
-
31444452779
-
Pioglitazone increases non-esterified fatty acid clearance in upper body obesity
-
Shadid S, Jensen MD (2006) Pioglitazone increases non-esterified fatty acid clearance in upper body obesity. Diabetologia 49: 149-157.
-
(2006)
Diabetologia
, vol.49
, pp. 149-157
-
-
Shadid, S.1
Jensen, M.D.2
-
45
-
-
12244288369
-
Duration of coffee- and exercise-induced changes in the fatty acid profile of human serum
-
Mougios V, Ring S, Petridou A, Nikolaidis MG (2003) Duration of coffee- and exercise-induced changes in the fatty acid profile of human serum. J Appl Physiol 94: 476-484.
-
(2003)
J Appl Physiol
, vol.94
, pp. 476-484
-
-
Mougios, V.1
Ring, S.2
Petridou, A.3
Nikolaidis, M.G.4
-
46
-
-
0037593888
-
Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival
-
Bedogni B, Pani G, Colavitti R, Riccio A, Borrello S, et al. (2003) Redox regulation of cAMP-responsive element-binding protein and induction of manganous superoxide dismutase in nerve growth factor-dependent cell survival. Journal of Biological Chemistry 278: 16510-16519.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 16510-16519
-
-
Bedogni, B.1
Pani, G.2
Colavitti, R.3
Riccio, A.4
Borrello, S.5
-
47
-
-
4444315545
-
Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis
-
Dhanasekaran A, Kotamraju S, Kalivendi SV, Matsunaga T, Shang T, et al. (2004) Supplementation of endothelial cells with mitochondria-targeted antioxidants inhibit peroxide-induced mitochondrial iron uptake, oxidative damage, and apoptosis. Journal of Biological Chemistry 279: 37575-37587.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 37575-37587
-
-
Dhanasekaran, A.1
Kotamraju, S.2
Kalivendi, S.V.3
Matsunaga, T.4
Shang, T.5
-
48
-
-
0038025936
-
Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia
-
Schafer M, Schafer C, Ewald N, Piper HM, Noll T (2003) Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia. Circulation Research 92: 1010-1015.
-
(2003)
Circulation Research
, vol.92
, pp. 1010-1015
-
-
Schafer, M.1
Schafer, C.2
Ewald, N.3
Piper, H.M.4
Noll, T.5
|