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Volumn 136, Issue 1, 2009, Pages 189-209

Improved prediction of malaria degradomes by supervised learning with SVM and profile kernel

Author keywords

Malaria; Parasite; Plasmodium; Protease; SVM

Indexed keywords

PEPTIDE HYDROLASE; PROTOZOAL PROTEIN;

EID: 63949088197     PISSN: 00166707     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10709-008-9336-9     Document Type: Article
Times cited : (22)

References (87)
  • 1
    • 22944473016 scopus 로고    scopus 로고
    • A malarial cysteine protease is necessary for Plasmodium sporozoite egress from oocysts
    • 10.1084/jem.20050545
    • AS Aly K Matuschewski 2005 A malarial cysteine protease is necessary for Plasmodium sporozoite egress from oocysts J Exp Med 202 225 230 10.1084/jem.20050545
    • (2005) J Exp Med , vol.202 , pp. 225-230
    • Aly, A.S.1    Matuschewski, K.2
  • 2
    • 34547667334 scopus 로고    scopus 로고
    • Phylogeny and evolution of the SERA multigene family in the genus Plasmodium
    • 10.1007/s00239-006-0253-1
    • N Arisue M Hirai M Arai H Matsuoka T Horii 2007 Phylogeny and evolution of the SERA multigene family in the genus Plasmodium J Mol Evol 65 82 91 10.1007/s00239-006-0253-1
    • (2007) J Mol Evol , vol.65 , pp. 82-91
    • Arisue, N.1    Hirai, M.2    Arai, M.3    Matsuoka, H.4    Horii, T.5
  • 4
    • 33750465167 scopus 로고    scopus 로고
    • Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malaria
    • 10.1371/journal.ppat.0020113
    • RP Baker R Wijetilaka S Urban 2006 Two Plasmodium rhomboid proteases preferentially cleave different adhesins implicated in all invasive stages of malaria PLoS Pathog 2 e113 10.1371/journal.ppat.0020113
    • (2006) PLoS Pathog , vol.2 , pp. 113
    • Baker, R.P.1    Wijetilaka, R.2    Urban, S.3
  • 5
    • 0032992330 scopus 로고    scopus 로고
    • Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase
    • 10.1073/pnas.96.11.6445
    • JC Barale T Blisnick H Fujioka PM Alzari M Aikawa C Braun-Breton G Langsley 1999 Plasmodium falciparum subtilisin-like protease 2, a merozoite candidate for the merozoite surface protein 1-42 maturase Proc Natl Acad Sci USA 96 6445 6450 10.1073/pnas.96.11.6445
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 6445-6450
    • Barale, J.C.1    Blisnick, T.2    Fujioka, H.3    Alzari, P.M.4    Aikawa, M.5    Braun-Breton, C.6    Langsley, G.7
  • 7
    • 4243071596 scopus 로고    scopus 로고
    • The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum
    • 10.1371/journal.pbio.0000005
    • Z Bozdech M Llinas BL Pulliam ED Wong J Zhu JL DeRisi 2003 The transcriptome of the intraerythrocytic developmental cycle of Plasmodium falciparum PLoS Biol 1 E5 10.1371/journal.pbio.0000005
    • (2003) PLoS Biol , vol.1 , pp. 5
    • Bozdech, Z.1    Llinas, M.2    Pulliam, B.L.3    Wong, E.D.4    Zhu, J.5    Derisi, J.L.6
  • 8
    • 1342303735 scopus 로고    scopus 로고
    • Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray
    • 10.1186/gb-2003-4-2-r9
    • Z Bozdech J Zhu MP Joachimiak FE Cohen B Pulliam JL DeRisi 2003 Expression profiling of the schizont and trophozoite stages of Plasmodium falciparum with a long-oligonucleotide microarray Genome Biol 4 R9 10.1186/gb-2003-4-2-r9
    • (2003) Genome Biol , vol.4 , pp. 9
    • Bozdech, Z.1    Zhu, J.2    Joachimiak, M.P.3    Cohen, F.E.4    Pulliam, B.5    Derisi, J.L.6
  • 9
    • 15244360655 scopus 로고    scopus 로고
    • A spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by Toxoplasma
    • 10.1073/pnas.0407918102
    • F Brossier TJ Jewett LD Sibley S Urban 2005 A spatially localized rhomboid protease cleaves cell surface adhesins essential for invasion by Toxoplasma Proc Natl Acad Sci USA 102 4146 4151 10.1073/pnas.0407918102
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 4146-4151
    • Brossier, F.1    Jewett, T.J.2    Sibley, L.D.3    Urban, S.4
  • 10
    • 0034681260 scopus 로고    scopus 로고
    • Regulated intramembrane proteolysis: A control mechanism conserved from bacteria to humans
    • 10.1016/S0092-8674(00)80675-3
    • MS Brown J Ye RB Rawson JL Goldstein 2000 Regulated intramembrane proteolysis: a control mechanism conserved from bacteria to humans Cell 100 391 398 10.1016/S0092-8674(00)80675-3
    • (2000) Cell , vol.100 , pp. 391-398
    • Brown, M.S.1    Ye, J.2    Rawson, R.B.3    Goldstein, J.L.4
  • 11
    • 0038404518 scopus 로고    scopus 로고
    • The Plasmodium vivax genome sequencing project
    • 10.1016/S1471-4922(03)00066-7
    • J Carlton 2003 The Plasmodium vivax genome sequencing project Trends Parasitol 19 227 231 10.1016/S1471-4922(03)00066-7
    • (2003) Trends Parasitol , vol.19 , pp. 227-231
    • Carlton, J.1
  • 14
    • 0035521154 scopus 로고    scopus 로고
    • Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets
    • 10.1016/S1471-4922(01)02037-2
    • GH Coombs DE Goldberg M Klemba C Berry J Kay JC Mottram 2001 Aspartic proteases of Plasmodium falciparum and other parasitic protozoa as drug targets Trends Parasitol 17 532 537 10.1016/S1471-4922(01)02037-2
    • (2001) Trends Parasitol , vol.17 , pp. 532-537
    • Coombs, G.H.1    Goldberg, D.E.2    Klemba, M.3    Berry, C.4    Kay, J.5    Mottram, J.C.6
  • 16
    • 19444382777 scopus 로고    scopus 로고
    • Apicomplexan rhomboids have a potential role in microneme protein cleavage during host cell invasion
    • 10.1016/j.ijpara.2005.04.001
    • TJ Dowse JC Pascall KD Brown D Soldati 2005 Apicomplexan rhomboids have a potential role in microneme protein cleavage during host cell invasion Int J Parasitol 35 747 756 10.1016/j.ijpara.2005.04.001
    • (2005) Int J Parasitol , vol.35 , pp. 747-756
    • Dowse, T.J.1    Pascall, J.C.2    Brown, K.D.3    Soldati, D.4
  • 17
    • 0033527572 scopus 로고    scopus 로고
    • Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum
    • 10.1074/jbc.274.45.32411
    • KK Eggleson KL Duffin DE Goldberg 1999 Identification and characterization of falcilysin, a metallopeptidase involved in hemoglobin catabolism within the malaria parasite Plasmodium falciparum J Biol Chem 274 32411 32417 10.1074/jbc.274.45.32411
    • (1999) J Biol Chem , vol.274 , pp. 32411-32417
    • Eggleson, K.K.1    Duffin, K.L.2    Goldberg, D.E.3
  • 19
    • 33747177314 scopus 로고    scopus 로고
    • Plasmepsins as potential targets for new antimalarial therapy
    • 10.1002/med.20082
    • K Ersmark B Samuelsson A Hallberg 2006 Plasmepsins as potential targets for new antimalarial therapy Med Res Rev 26 626 666 10.1002/med.20082
    • (2006) Med Res Rev , vol.26 , pp. 626-666
    • Ersmark, K.1    Samuelsson, B.2    Hallberg, A.3
  • 20
    • 0019797407 scopus 로고
    • Evolutionary trees from DNA sequences: A maximum likelihood approach
    • 10.1007/BF01734359
    • J Felsenstein 1981 Evolutionary trees from DNA sequences: a maximum likelihood approach J Mol Evol 17 368 376 10.1007/BF01734359
    • (1981) J Mol Evol , vol.17 , pp. 368-376
    • Felsenstein, J.1
  • 26
    • 24144494578 scopus 로고    scopus 로고
    • Hemoglobin degradation
    • 10.1007/3-540-29088-5-11
    • DE Goldberg 2005 Hemoglobin degradation Curr Top Microbiol Immunol 295 275 291 10.1007/3-540-29088-5-11
    • (2005) Curr Top Microbiol Immunol , vol.295 , pp. 275-291
    • Goldberg, D.E.1
  • 27
    • 0043092063 scopus 로고    scopus 로고
    • Surface coat remodeling during differentiation of Trypanosoma brucei
    • 10.1074/jbc.M301497200
    • AE Gruszynski A DeMaster NM Hooper JD Bangs 2003 Surface coat remodeling during differentiation of Trypanosoma brucei J Biol Chem 278 24665 24672 10.1074/jbc.M301497200
    • (2003) J Biol Chem , vol.278 , pp. 24665-24672
    • Gruszynski, A.E.1    Demaster, A.2    Hooper, N.M.3    Bangs, J.D.4
  • 28
    • 0032887161 scopus 로고    scopus 로고
    • PfSUB-2: A second subtilisin-like protein in Plasmodium falciparum merozoites
    • 10.1016/S0166-6851(99)00122-X
    • F Hackett M Sajid C Withers-Martinez M Grainger MJ Blackman 1999 PfSUB-2: a second subtilisin-like protein in Plasmodium falciparum merozoites Mol Biochem Parasitol 103 183 195 10.1016/S0166-6851(99)00122-X
    • (1999) Mol Biochem Parasitol , vol.103 , pp. 183-195
    • Hackett, F.1    Sajid, M.2    Withers-Martinez, C.3    Grainger, M.4    Blackman, M.J.5
  • 31
    • 0042526632 scopus 로고    scopus 로고
    • Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA
    • 10.1074/jbc.M211311200
    • M Herlan F Vogel C Bornhovd W Neupert AS Reichert 2003 Processing of Mgm1 by the rhomboid-type protease Pcp1 is required for maintenance of mitochondrial morphology and of mitochondrial DNA J Biol Chem 278 27781 27788 10.1074/jbc.M211311200
    • (2003) J Biol Chem , vol.278 , pp. 27781-27788
    • Herlan, M.1    Vogel, F.2    Bornhovd, C.3    Neupert, W.4    Reichert, A.S.5
  • 33
    • 14644390170 scopus 로고    scopus 로고
    • Novel predicted peptidases with a potential role in the ubiquitin signaling pathway
    • LM Iyer EV Koonin L Aravind 2004 Novel predicted peptidases with a potential role in the ubiquitin signaling pathway Cell Cycle 3 1440 1450
    • (2004) Cell Cycle , vol.3 , pp. 1440-1450
    • Iyer, L.M.1    Koonin, E.V.2    Aravind, L.3
  • 34
    • 0034048878 scopus 로고    scopus 로고
    • A discriminative framework for detecting remote protein homologies
    • 10.1089/10665270050081405
    • T Jaakkola M Diekhans D Haussler 2000 A discriminative framework for detecting remote protein homologies J Comput Biol 7 95 114 10.1089/ 10665270050081405
    • (2000) J Comput Biol , vol.7 , pp. 95-114
    • Jaakkola, T.1    Diekhans, M.2    Haussler, D.3
  • 35
    • 0035479334 scopus 로고    scopus 로고
    • Aspartyl proteinase genes from apicomplexan parasites: Evidence for evolution of the gene structure
    • 10.1016/S1471-4922(01)02030-X
    • L Jean M Long J Young P Pery F Tomley 2001 Aspartyl proteinase genes from apicomplexan parasites: evidence for evolution of the gene structure Trends Parasitol 17 491 498 10.1016/S1471-4922(01)02030-X
    • (2001) Trends Parasitol , vol.17 , pp. 491-498
    • Jean, L.1    Long, M.2    Young, J.3    Pery, P.4    Tomley, F.5
  • 36
    • 0032438987 scopus 로고    scopus 로고
    • Hidden Markov models for detecting remote protein homologies
    • 10.1093/bioinformatics/14.10.846
    • K Karplus C Barrett R Hughey 1998 Hidden Markov models for detecting remote protein homologies Bioinformatics 14 846 856 10.1093/bioinformatics/14. 10.846
    • (1998) Bioinformatics , vol.14 , pp. 846-856
    • Karplus, K.1    Barrett, C.2    Hughey, R.3
  • 38
    • 0030041781 scopus 로고    scopus 로고
    • Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast
    • M Knop A Finger T Braun K Hellmuth DH Wolf 1996 Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast EMBO J 15 753 763
    • (1996) EMBO J , vol.15 , pp. 753-763
    • Knop, M.1    Finger, A.2    Braun, T.3    Hellmuth, K.4    Wolf, D.H.5
  • 39
    • 22544448378 scopus 로고    scopus 로고
    • Profile-based string kernels for remote homology detection and motif extraction
    • 10.1142/S021972000500120X
    • R Kuang E Ie K Wang K Wang M Siddiqi Y Freund C Leslie 2005 Profile-based string kernels for remote homology detection and motif extraction J Bioinform Comput Biol 3 527 550 10.1142/S021972000500120X
    • (2005) J Bioinform Comput Biol , vol.3 , pp. 527-550
    • Kuang, R.1    Ie, E.2    Wang, K.3    Wang, K.4    Siddiqi, M.5    Freund, Y.6    Leslie, C.7
  • 40
    • 0042591317 scopus 로고    scopus 로고
    • Expression and function of the Trypanosoma brucei major surface protease (GP63) genes
    • 10.1074/jbc.M301451200
    • DJ LaCount AE Gruszynski PM Grandgenett JD Bangs JE Donelson 2003 Expression and function of the Trypanosoma brucei major surface protease (GP63) genes J Biol Chem 278 24658 24664 10.1074/jbc.M301451200
    • (2003) J Biol Chem , vol.278 , pp. 24658-24664
    • Lacount, D.J.1    Gruszynski, A.E.2    Grandgenett, P.M.3    Bangs, J.D.4    Donelson, J.E.5
  • 42
    • 34047158115 scopus 로고    scopus 로고
    • The role of metacaspase 1 in Plasmodium berghei development and apoptosis
    • 10.1016/j.molbiopara.2007.01.016
    • L Le Chat RE Sinden JT Dessens 2007 The role of metacaspase 1 in Plasmodium berghei development and apoptosis Mol Biochem Parasitol 153 41 47 10.1016/j.molbiopara.2007.01.016
    • (2007) Mol Biochem Parasitol , vol.153 , pp. 41-47
    • Le Chat, L.1    Sinden, R.E.2    Dessens, J.T.3
  • 45
    • 1542714925 scopus 로고    scopus 로고
    • Mismatch string kernels for discriminative protein classification
    • 10.1093/bioinformatics/btg431
    • CS Leslie E Eskin A Cohen J Weston WS Noble 2004 Mismatch string kernels for discriminative protein classification Bioinformatics 20 467 476 10.1093/bioinformatics/btg431
    • (2004) Bioinformatics , vol.20 , pp. 467-476
    • Leslie, C.S.1    Eskin, E.2    Cohen, A.3    Weston, J.4    Noble, W.S.5
  • 47
    • 0742287001 scopus 로고    scopus 로고
    • Combining pairwise sequence similarity and support vector machines for detecting remote protein evolutionary and structural relationships
    • 10.1089/106652703322756113
    • L Liao WS Noble 2003 Combining pairwise sequence similarity and support vector machines for detecting remote protein evolutionary and structural relationships J Comput Biol 10 857 868 10.1089/106652703322756113
    • (2003) J Comput Biol , vol.10 , pp. 857-868
    • Liao, L.1    Noble, W.S.2
  • 49
    • 0036049784 scopus 로고    scopus 로고
    • Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum
    • 10.1046/j.1365-2958.2002.03105.x
    • P Malhotra PV Dasaradhi A Kumar A Mohmmed N Agrawal RK Bhatnagar VS Chauhan 2002 Double-stranded RNA-mediated gene silencing of cysteine proteases (falcipain-1 and -2) of Plasmodium falciparum Mol Microbiol 45 1245 1254 10.1046/j.1365-2958.2002.03105.x
    • (2002) Mol Microbiol , vol.45 , pp. 1245-1254
    • Malhotra, P.1    Dasaradhi, P.V.2    Kumar, A.3    Mohmmed, A.4    Agrawal, N.5    Bhatnagar, R.K.6    Chauhan, V.S.7
  • 50
    • 36749042579 scopus 로고    scopus 로고
    • Evidence for a common role for the serine-type Plasmodium falciparum serine repeat antigen proteases: Implications for vaccine and drug design
    • 10.1128/IAI.00405-07
    • JE McCoubrie SK Miller T Sargeant RT Good AN Hodder TP Speed TF de Koning-Ward BS Crabb 2007 Evidence for a common role for the serine-type Plasmodium falciparum serine repeat antigen proteases: implications for vaccine and drug design Infect Immun 75 5565 5574 10.1128/IAI.00405-07
    • (2007) Infect Immun , vol.75 , pp. 5565-5574
    • McCoubrie, J.E.1    Miller, S.K.2    Sargeant, T.3    Good, R.T.4    Hodder, A.N.5    Speed, T.P.6    De Koning-Ward, T.F.7    Crabb, B.S.8
  • 51
    • 0038700756 scopus 로고    scopus 로고
    • Mitochondrial membrane remodelling regulated by a conserved rhomboid protease
    • 10.1038/nature01633
    • GA McQuibban S Saurya M Freeman 2003 Mitochondrial membrane remodelling regulated by a conserved rhomboid protease Nature 423 537 541 10.1038/nature01633
    • (2003) Nature , vol.423 , pp. 537-541
    • McQuibban, G.A.1    Saurya, S.2    Freeman, M.3
  • 52
    • 34249866547 scopus 로고    scopus 로고
    • Features of apoptosis in Plasmodium falciparum erythrocytic stage through a putative role of PfMCA1 metacaspase-like protein
    • 10.1086/518253
    • B Meslin C Barnadas V Boni C Latour F De Monbrison K Kaiser S Picot 2007 Features of apoptosis in Plasmodium falciparum erythrocytic stage through a putative role of PfMCA1 metacaspase-like protein J Infect Dis 195 1852 1859 10.1086/518253
    • (2007) J Infect Dis , vol.195 , pp. 1852-1859
    • Meslin, B.1    Barnadas, C.2    Boni, V.3    Latour, C.4    De Monbrison, F.5    Kaiser, K.6    Picot, S.7
  • 54
    • 0141733057 scopus 로고    scopus 로고
    • Plasmodium falciparum falcilysin: A metalloprotease with dual specificity
    • 10.1074/jbc.M306842200
    • CE Murata DE Goldberg 2003 Plasmodium falciparum falcilysin: a metalloprotease with dual specificity J Biol Chem 278 38022 38028 10.1074/jbc.M306842200
    • (2003) J Biol Chem , vol.278 , pp. 38022-38028
    • Murata, C.E.1    Goldberg, D.E.2
  • 55
    • 0037836069 scopus 로고    scopus 로고
    • Plasmodium falciparum falcilysin: An unprocessed food vacuole enzyme
    • 10.1016/S0166-6851(03)00098-7
    • CE Murata DE Goldberg 2003 Plasmodium falciparum falcilysin: an unprocessed food vacuole enzyme Mol Biochem Parasitol 129 123 126 10.1016/S0166-6851(03)00098-7
    • (2003) Mol Biochem Parasitol , vol.129 , pp. 123-126
    • Murata, C.E.1    Goldberg, D.E.2
  • 56
    • 0028961335 scopus 로고
    • SCOP: A structural classification of proteins database for the investigation of sequences and structures
    • AG Murzin SE Brenner T Hubbard C Chothia 1995 SCOP: a structural classification of proteins database for the investigation of sequences and structures J Mol Biol 247 536 540
    • (1995) J Mol Biol , vol.247 , pp. 536-540
    • Murzin, A.G.1    Brenner, S.E.2    Hubbard, T.3    Chothia, C.4
  • 57
    • 0034623005 scopus 로고    scopus 로고
    • T-coffee: A novel method for fast and accurate multiple sequence alignment
    • 10.1006/jmbi.2000.4042
    • C Notredame DG Higgins J Heringa 2000 T-coffee: a novel method for fast and accurate multiple sequence alignment J Mol Biol 302 205 217 10.1006/jmbi.2000.4042
    • (2000) J Mol Biol , vol.302 , pp. 205-217
    • Notredame, C.1    Higgins, D.G.2    Heringa, J.3
  • 58
    • 33749327877 scopus 로고    scopus 로고
    • Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase
    • 10.1096/fj.06-5762com
    • AC Nyborg TB Ladd K Jansen T Kukar TE Golde 2006 Intramembrane proteolytic cleavage by human signal peptide peptidase like 3 and malaria signal peptide peptidase FASEB J 20 1671 1679 10.1096/fj.06-5762com
    • (2006) FASEB J , vol.20 , pp. 1671-1679
    • Nyborg, A.C.1    Ladd, T.B.2    Jansen, K.3    Kukar, T.4    Golde, T.E.5
  • 60
    • 33751432934 scopus 로고    scopus 로고
    • Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion
    • 10.1371/journal.ppat.0020117
    • KC Pandey N Singh S Arastu-Kapur M Bogyo PJ Rosenthal 2006 Falstatin, a cysteine protease inhibitor of Plasmodium falciparum, facilitates erythrocyte invasion PLoS Pathog 2 e117 10.1371/journal.ppat.0020117
    • (2006) PLoS Pathog , vol.2 , pp. 117
    • Pandey, K.C.1    Singh, N.2    Arastu-Kapur, S.3    Bogyo, M.4    Rosenthal, P.J.5
  • 61
    • 33846077153 scopus 로고    scopus 로고
    • A role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplast
    • 10.1111/j.1365-2958.2006.05443.x
    • M Ponpuak M Klemba M Park IY Gluzman GK Lamppa DE Goldberg 2007 A role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplast Mol Microbiol 63 314 334 10.1111/j.1365-2958.2006.05443.x
    • (2007) Mol Microbiol , vol.63 , pp. 314-334
    • Ponpuak, M.1    Klemba, M.2    Park, M.3    Gluzman, I.Y.4    Lamppa, G.K.5    Goldberg, D.E.6
  • 62
    • 0036882396 scopus 로고    scopus 로고
    • Irreversible inhibitors of serine, cysteine, and threonine proteases
    • 10.1021/cr010182v
    • JC Powers JL Asgian OD Ekici KE James 2002 Irreversible inhibitors of serine, cysteine, and threonine proteases Chem Rev 102 4639 4750 10.1021/cr010182v
    • (2002) Chem Rev , vol.102 , pp. 4639-4750
    • Powers, J.C.1    Asgian, J.L.2    Ekici, O.D.3    James, K.E.4
  • 64
    • 33847300136 scopus 로고    scopus 로고
    • Characterization and localization of Plasmodium falciparum homolog of prokaryotic ClpQ/HslV protease
    • 10.1016/j.molbiopara.2007.01.002
    • G Ramasamy D Gupta A Mohmmed VS Chauhan 2007 Characterization and localization of Plasmodium falciparum homolog of prokaryotic ClpQ/HslV protease Mol Biochem Parasitol 152 139 148 10.1016/j.molbiopara.2007.01.002
    • (2007) Mol Biochem Parasitol , vol.152 , pp. 139-148
    • Ramasamy, G.1    Gupta, D.2    Mohmmed, A.3    Chauhan, V.S.4
  • 65
    • 28444492998 scopus 로고    scopus 로고
    • Profile-based direct kernels for remote homology detection and fold recognition
    • 10.1093/bioinformatics/bti687
    • H Rangwala G Karypis 2005 Profile-based direct kernels for remote homology detection and fold recognition Bioinformatics 21 4239 4247 10.1093/bioinformatics/bti687
    • (2005) Bioinformatics , vol.21 , pp. 4239-4247
    • Rangwala, H.1    Karypis, G.2
  • 67
    • 0036183460 scopus 로고    scopus 로고
    • Hydrolysis of erythrocyte proteins by proteases of malaria parasites
    • 10.1097/00062752-200203000-00010
    • PJ Rosenthal 2002 Hydrolysis of erythrocyte proteins by proteases of malaria parasites Curr Opin Hematol 9 140 145 10.1097/00062752-200203000-00010
    • (2002) Curr Opin Hematol , vol.9 , pp. 140-145
    • Rosenthal, P.J.1
  • 68
    • 12744262976 scopus 로고    scopus 로고
    • Cysteine proteases of malaria parasites
    • 10.1016/j.ijpara.2004.10.003
    • PJ Rosenthal 2004 Cysteine proteases of malaria parasites Int J Parasitol 34 1489 1499 10.1016/j.ijpara.2004.10.003
    • (2004) Int J Parasitol , vol.34 , pp. 1489-1499
    • Rosenthal, P.J.1
  • 69
    • 0035986688 scopus 로고    scopus 로고
    • Cysteine proteases of malaria parasites: Targets for chemotherapy
    • 10.2174/1381612023394197
    • PJ Rosenthal PS Sijwali A Singh BR Shenai 2002 Cysteine proteases of malaria parasites: targets for chemotherapy Curr Pharm Des 8 1659 1672 10.2174/1381612023394197
    • (2002) Curr Pharm des , vol.8 , pp. 1659-1672
    • Rosenthal, P.J.1    Sijwali, P.S.2    Singh, A.3    Shenai, B.R.4
  • 70
    • 0032436499 scopus 로고    scopus 로고
    • Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors
    • 10.1016/S0968-0896(98)80022-9
    • KA Scheidt WR Roush JH McKerrow PM Selzer E Hansell PJ Rosenthal 1998 Structure-based design, synthesis and evaluation of conformationally constrained cysteine protease inhibitors Bioorg Med Chem 6 2477 2494 10.1016/S0968-0896(98) 80022-9
    • (1998) Bioorg Med Chem , vol.6 , pp. 2477-2494
    • Scheidt, K.A.1    Roush, W.R.2    McKerrow, J.H.3    Selzer, P.M.4    Hansell, E.5    Rosenthal, P.J.6
  • 71
    • 34547620272 scopus 로고    scopus 로고
    • Malarial protease inhibitors: Potential new chemotherapeutic agents
    • A Sharma 2007 Malarial protease inhibitors: potential new chemotherapeutic agents Curr Opin Investig Drugs 8 642 652
    • (2007) Curr Opin Investig Drugs , vol.8 , pp. 642-652
    • Sharma, A.1
  • 72
    • 0034666133 scopus 로고    scopus 로고
    • Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum
    • 10.1074/jbc.M004459200
    • BR Shenai PS Sijwali A Singh PJ Rosenthal 2000 Characterization of native and recombinant falcipain-2, a principal trophozoite cysteine protease and essential hemoglobinase of Plasmodium falciparum J Biol Chem 275 29000 29010 10.1074/jbc.M004459200
    • (2000) J Biol Chem , vol.275 , pp. 29000-29010
    • Shenai, B.R.1    Sijwali, P.S.2    Singh, A.3    Rosenthal, P.J.4
  • 73
    • 0035985069 scopus 로고    scopus 로고
    • Stage-specific antimalarial activity of cysteine protease inhibitors
    • 10.1515/BC.2002.089
    • BR Shenai AV Semenov PJ Rosenthal 2002 Stage-specific antimalarial activity of cysteine protease inhibitors Biol Chem 383 843 847 10.1515/BC.2002.089
    • (2002) Biol Chem , vol.383 , pp. 843-847
    • Shenai, B.R.1    Semenov, A.V.2    Rosenthal, P.J.3
  • 74
    • 1842533231 scopus 로고    scopus 로고
    • Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum
    • 10.1073/pnas.0307720101
    • PS Sijwali PJ Rosenthal 2004 Gene disruption confirms a critical role for the cysteine protease falcipain-2 in hemoglobin hydrolysis by Plasmodium falciparum Proc Natl Acad Sci USA 101 4384 4389 10.1073/pnas.0307720101
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 4384-4389
    • Sijwali, P.S.1    Rosenthal, P.J.2
  • 75
    • 0035644195 scopus 로고    scopus 로고
    • Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3
    • 10.1042/0264-6021:3600481
    • PS Sijwali BR Shenai J Gut A Singh PJ Rosenthal 2001 Expression and characterization of the Plasmodium falciparum haemoglobinase falcipain-3 Biochem J 360 481 489 10.1042/0264-6021:3600481
    • (2001) Biochem J , vol.360 , pp. 481-489
    • Sijwali, P.S.1    Shenai, B.R.2    Gut, J.3    Singh, A.4    Rosenthal, P.J.5
  • 76
    • 33748328016 scopus 로고    scopus 로고
    • Gene disruptions demonstrate independent roles for the four falcipain cysteine proteases of Plasmodium falciparum
    • 10.1016/j.molbiopara.2006.06.013
    • PS Sijwali J Koo N Singh PJ Rosenthal 2006 Gene disruptions demonstrate independent roles for the four falcipain cysteine proteases of Plasmodium falciparum Mol Biochem Parasitol 150 96 106 10.1016/j.molbiopara.2006.06.013
    • (2006) Mol Biochem Parasitol , vol.150 , pp. 96-106
    • Sijwali, P.S.1    Koo, J.2    Singh, N.3    Rosenthal, P.J.4
  • 77
    • 0035827339 scopus 로고    scopus 로고
    • A genomic perspective on human proteases
    • 10.1016/S0014-5793(01)02490-5
    • C Southan 2001 A genomic perspective on human proteases FEBS Lett 498 214 218 10.1016/S0014-5793(01)02490-5
    • (2001) FEBS Lett , vol.498 , pp. 214-218
    • Southan, C.1
  • 78
    • 27744568481 scopus 로고    scopus 로고
    • The Plasmodium protein network diverges from those of other eukaryotes
    • 10.1038/nature04135
    • S Suthram T Sittler T Ideker 2005 The Plasmodium protein network diverges from those of other eukaryotes Nature 438 108 112 10.1038/nature04135
    • (2005) Nature , vol.438 , pp. 108-112
    • Suthram, S.1    Sittler, T.2    Ideker, T.3
  • 79
    • 34547781750 scopus 로고    scopus 로고
    • MEGA4: Molecular evolutionary genetics analysis (MEGA) software version 4.0
    • 10.1093/molbev/msm092
    • K Tamura J Dudley M Nei S Kumar 2007 MEGA4: molecular evolutionary genetics analysis (MEGA) software version 4.0 Mol Biol Evol 24 1596 1599 10.1093/molbev/msm092
    • (2007) Mol Biol Evol , vol.24 , pp. 1596-1599
    • Tamura, K.1    Dudley, J.2    Nei, M.3    Kumar, S.4
  • 80
    • 0035913908 scopus 로고    scopus 로고
    • Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases
    • 10.1016/S0092-8674(01)00525-6
    • S Urban JR Lee M Freeman 2001 Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases Cell 107 173 182 10.1016/S0092-8674(01) 00525-6
    • (2001) Cell , vol.107 , pp. 173-182
    • Urban, S.1    Lee, J.R.2    Freeman, M.3
  • 81
    • 0037015265 scopus 로고    scopus 로고
    • Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids
    • 10.1016/S0960-9822(02)01092-8
    • S Urban D Schlieper M Freeman 2002 Conservation of intramembrane proteolytic activity and substrate specificity in prokaryotic and eukaryotic rhomboids Curr Biol 12 1507 1512 10.1016/S0960-9822(02)01092-8
    • (2002) Curr Biol , vol.12 , pp. 1507-1512
    • Urban, S.1    Schlieper, D.2    Freeman, M.3
  • 83
    • 1642565128 scopus 로고    scopus 로고
    • Computer assisted searches for drug targets with emphasis on malarial proteases and their inhibitors
    • 10.2174/1568005043480952
    • Y Wang Y Wu 2004 Computer assisted searches for drug targets with emphasis on malarial proteases and their inhibitors Curr Drug Targets Infect Disord 4 25 40 10.2174/1568005043480952
    • (2004) Curr Drug Targets Infect Disord , vol.4 , pp. 25-40
    • Wang, Y.1    Wu, Y.2
  • 84
    • 33750886311 scopus 로고    scopus 로고
    • Crystal structure of a rhomboid family intramembrane protease
    • 10.1038/nature05255
    • Y Wang Y Zhang Y Ha 2006 Crystal structure of a rhomboid family intramembrane protease Nature 444 179 180 10.1038/nature05255
    • (2006) Nature , vol.444 , pp. 179-180
    • Wang, Y.1    Zhang, Y.2    Ha, Y.3
  • 85
    • 3142547280 scopus 로고    scopus 로고
    • Subtilisin-like proteases of the malaria parasite
    • 10.1111/j.1365-2958.2004.04144.x
    • C Withers-Martinez L Jean MJ Blackman 2004 Subtilisin-like proteases of the malaria parasite Mol Microbiol 53 55 63 10.1111/j.1365-2958.2004.04144.x
    • (2004) Mol Microbiol , vol.53 , pp. 55-63
    • Withers-Martinez, C.1    Jean, L.2    Blackman, M.J.3
  • 86
    • 0242669367 scopus 로고    scopus 로고
    • Data-mining approaches reveal hidden families of proteases in the genome of malaria parasite
    • 10.1101/gr.913403
    • YM Wu XY Wang X Liu YF Wang 2003 Data-mining approaches reveal hidden families of proteases in the genome of malaria parasite Genome Res 13 601 616 10.1101/gr.913403
    • (2003) Genome Res , vol.13 , pp. 601-616
    • Wu, Y.M.1    Wang, X.Y.2    Liu, X.3    Wang, Y.F.4


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