DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide

International Journal of Cancer

Volumn 124, Issue 9, 2009, Pages 2006-2015

  Von Tungeln, Linda S ^a   Churchwell, Mona I ^a   Doerge, Daniel R ^a   Shaddock, Joseph G ^a   McGarrity, Lynda J ^a   Heflich, Robert H ^a   Da Costa, Gonçalo Gamboa ^a,b   Marques, M Matilde ^b   Beland, Frederick A ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b INSTITUTO SUPERIOR TÉCNICO   (Portugal)

Author keywords

Acrylamide; DNA adducts; Glycidamide; Micronuclei; Mutations

Indexed keywords

3 (2 CARBAMOYL 2 HYDROXYETHYL)ADENINE; 7 (2 CARBAMOYL 2 HYDROXYETHYL)GUANINE; ACRYLAMIDE; GLYCIDAMIDE; GUANINE DERIVATIVE; UNCLASSIFIED DRUG; EPOXIDE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHEMICAL CARCINOGENESIS; CONTROLLED STUDY; DNA ADDUCT; ERYTHROCYTE; FEMALE; GENE FREQUENCY; GENE MUTATION; HETEROZYGOSITY LOSS; LYMPHOCYTE CLONE; MALE; MICRONUCLEUS; MORTALITY; MOUSE; MUTAGENESIS; MUTATIONAL ANALYSIS; NEWBORN; NEWBORN PERIOD; NONHUMAN; PRIORITY JOURNAL; RETICULOCYTE; SPLEEN CELL; ANIMAL; BODY WEIGHT; C3H MOUSE; C57BL MOUSE; CELL NUCLEUS; DRUG EFFECT; GENETICS; LYMPHOCYTE; METABOLISM; MICRONUCLEUS TEST; MOUSE MUTANT; MUTAGEN TESTING; MUTATION;

ACRYLAMIDE; ANIMALS; ANIMALS, NEWBORN; BODY WEIGHT; CELL NUCLEUS; DNA ADDUCTS; EPOXY COMPOUNDS; ERYTHROCYTES; FEMALE; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; LOSS OF HETEROZYGOSITY; LYMPHOCYTES; MALE; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, KNOCKOUT; MICRONUCLEI, CHROMOSOME-DEFECTIVE; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; MUTATION; RETICULOCYTES; THYMIDINE KINASE;

EID: 63449122295     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.24165     Document Type: Article

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