메뉴 건너뛰기




Volumn 19, Issue 4, 2004, Pages 307-311

Frequency of Tk and Hprt lymphocyte mutants and bone marrow micronuclei in mice treated neonatally with zidovudine and didanosine

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; BROXURIDINE; DIDANOSINE; DIMETHYL SULFOXIDE; ETHYLNITROSOUREA; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MUTANT PROTEIN; NUCLEOSIDE ANALOG; THYMIDINE KINASE; ZIDOVUDINE;

EID: 3543129486     PISSN: 02678357     EISSN: None     Source Type: Journal    
DOI: 10.1093/mutage/geh033     Document Type: Article
Times cited : (12)

References (36)
  • 1
    • 0024353605 scopus 로고
    • Biochemical pharmacology of zidovudine in human T-lymphoblastoid cells (CEM)
    • Avramis,V.I., Markson,W., Jackson,R.L. and Gomperts,E. (1989) Biochemical pharmacology of zidovudine in human T-lymphoblastoid cells (CEM). AIDS, 3, 417-422.
    • (1989) AIDS , vol.3 , pp. 417-422
    • Avramis, V.I.1    Markson, W.2    Jackson, R.L.3    Gomperts, E.4
  • 2
    • 0034699898 scopus 로고    scopus 로고
    • Adverse effects of antiretroviral therapy
    • Carr,A. and Cooper,D.A. (2000) Adverse effects of antiretroviral therapy. Lancet, 356, 1423-1430.
    • (2000) Lancet , vol.356 , pp. 1423-1430
    • Carr, A.1    Cooper, D.A.2
  • 3
    • 0023189465 scopus 로고
    • Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs
    • Cheng,Y.-c., Dutschman,G.E., Bastow,K.F., Sarngadharan,M.G. and Ting,R.Y.C. (1987) Human immunodeficiency virus reverse transcriptase. General properties and its interactions with nucleoside triphosphate analogs. J. Biol. Chem., 262, 2187-2189.
    • (1987) J. Biol. Chem. , vol.262 , pp. 2187-2189
    • Cheng, Y.-C.1    Dutschman, G.E.2    Bastow, K.F.3    Sarngadharan, M.G.4    Ting, R.Y.C.5
  • 5
    • 0033601826 scopus 로고    scopus 로고
    • +/- mouse model for detecting in vivo mutation in an endogenous, autosomal gene
    • +/- mouse model for detecting in vivo mutation in an endogenous, autosomal gene. Mutat. Res., 423, 125-136.
    • (1999) Mutat. Res. , vol.423 , pp. 125-136
    • Dobrovolsky, V.N.1    Casciano, D.A.2    Heflich, R.H.3
  • 6
    • 0032850799 scopus 로고    scopus 로고
    • Molecular analysis of in vivo mutations induced by N-ethyl-N-nitrosourea in the autosomal Tk and the X-linked Hprt genes of mouse lymphocytes
    • Dobrovolsky,V.N., Chen,T. and Heflich,R.H. (1999b) Molecular analysis of in vivo mutations induced by N-ethyl-N-nitrosourea in the autosomal Tk and the X-linked Hprt genes of mouse lymphocytes. Environ. Mol. Mutagen., 34, 30-38.
    • (1999) Environ. Mol. Mutagen. , vol.34 , pp. 30-38
    • Dobrovolsky, V.N.1    Chen, T.2    Heflich, R.H.3
  • 7
    • 0026032318 scopus 로고
    • Anti-human immunodeficiency virus synergism by zidovudine (3′-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells
    • Dornsife,R.E., St Clair,M.H., Huang,A.T., Panella,T.J., Koszalka,G.W., Burns,C.L. and Averett,D.R. (1991) Anti-human immunodeficiency virus synergism by zidovudine (3′-azidothymidine) and didanosine (dideoxyinosine) contrasts with their additive inhibition of normal human marrow progenitor cells. Antimicrob. Agents Chemother., 35, 322-328.
    • (1991) Antimicrob. Agents Chemother. , vol.35 , pp. 322-328
    • Dornsife, R.E.1    St Clair, M.H.2    Huang, A.T.3    Panella, T.J.4    Koszalka, G.W.5    Burns, C.L.6    Averett, D.R.7
  • 8
    • 0026721305 scopus 로고
    • Didanosine. A review of its antiviral activity, pharmacokinetic properties and therapeutic potential in human immunodeficiency virus infection
    • Faulds,D. and Brogden,R.N. (1992) Didanosine. A review of its antiviral activity, pharmacokinetic properties and therapeutic potential in human immunodeficiency virus infection. Drugs, 44, 94-116.
    • (1992) Drugs , vol.44 , pp. 94-116
    • Faulds, D.1    Brogden, R.N.2
  • 10
    • 0033549284 scopus 로고    scopus 로고
    • Zidovudine didanosine and zalcitabine in the treatment of HIV infection: Meta-analyses of the randomised evidence
    • HIV Trialists' Collaborative Group
    • HIV Trialists' Collaborative Group (1999) Zidovudine, didanosine and zalcitabine in the treatment of HIV infection: meta-analyses of the randomised evidence. Lancet, 353, 2014-2025.
    • (1999) Lancet , vol.353 , pp. 2014-2025
  • 11
    • 0025339708 scopus 로고
    • Selective action of 3′-azido-3′-deoxythymidine 5′-triphosphate on viral reverse transcriptases and human DNA polymerases
    • Huang,P., Farquhar,D. and Plunkett,W. (1990) Selective action of 3′-azido-3′-deoxythymidine 5′-triphosphate on viral reverse transcriptases and human DNA polymerases. J. Biol. Chem., 265, 11914-11918.
    • (1990) J. Biol. Chem. , vol.265 , pp. 11914-11918
    • Huang, P.1    Farquhar, D.2    Plunkett, W.3
  • 12
    • 0033940419 scopus 로고    scopus 로고
    • Zidovudine (AZT)
    • IARC Some Antiviral and Antineoplastic Drugs and Other Pharmaceutical Agents. IARC, Lyon
    • IARC (2000) Zidovudine (AZT). In IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 76, Some Antiviral and Antineoplastic Drugs and Other Pharmaceutical Agents. IARC, Lyon, pp. 73-127.
    • (2000) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , vol.76 , pp. 73-127
  • 14
    • 0028990381 scopus 로고
    • Mitochondrial toxicity of antiviral drugs
    • Lewis,W. and Dalakas,M.C. (1995) Mitochondrial toxicity of antiviral drugs. Nature Med., 1, 417-422.
    • (1995) Nature Med. , vol.1 , pp. 417-422
    • Lewis, W.1    Dalakas, M.C.2
  • 17
    • 0036305980 scopus 로고    scopus 로고
    • Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3′-azido-3′-deoxythymidine and 2′,3′ -dideoxyinosine
    • Meng,Q., Su,T., O'Neill,J.P. and Walker,V.E. (2002) Molecular analysis of mutations at the HPRT and TK loci of human lymphoblastoid cells after combined treatments with 3′-azido-3′ -deoxythymidine and 2′,3′-dideoxyinosine. Environ. Mol. Mutagen., 39, 282-295.
    • (2002) Environ. Mol. Mutagen. , vol.39 , pp. 282-295
    • Meng, Q.1    Su, T.2    O'Neill, J.P.3    Walker, V.E.4
  • 19
    • 0028146656 scopus 로고
    • Enzymatic phosphorylation and pyrophosphorylation of 2′,3′-dideoxyadenosine-5′-monophosphate, a key metabolite in the pathway for activation of the anti-HIV (human immunodeficiency virus) agent 2′,3′-dideoxyinosine
    • Navé,J.-F., Eschbach,A., Wolff-Kugel,D., Halazy,S. and Balzarini,J. (1994) Enzymatic phosphorylation and pyrophosphorylation of 2′,3′-dideoxyadenosine-5′-monophosphate, a key metabolite in the pathway for activation of the anti-HIV (human immunodeficiency virus) agent 2′,3′-dideoxyinosine. Biochem. Pharmacol., 48, 1105-1112.
    • (1994) Biochem. Pharmacol. , vol.48 , pp. 1105-1112
    • Navé, J.-F.1    Eschbach, A.2    Wolff-Kugel, D.3    Halazy, S.4    Balzarini, J.5
  • 20
    • 0026604666 scopus 로고
    • Interactions of azidothymidine triphosphate with the cellular DNA polymerases α, δ and E with DNA primase
    • Nickel,W., Austermann,S., Bialek,G. and Grosse,F. (1992) Interactions of azidothymidine triphosphate with the cellular DNA polymerases α, δ and E with DNA primase. J. Biol. Chem., 267, 848-854.
    • (1992) J. Biol. Chem. , vol.267 , pp. 848-854
    • Nickel, W.1    Austermann, S.2    Bialek, G.3    Grosse, F.4
  • 23
    • 0027960180 scopus 로고
    • Intracellular metabolism of 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine in combination in the absence and presence of ribavirin
    • Palmer,S. and Cox,S. (1994) Intracellular metabolism of 3′-azido-3′-deoxythymidine and 2′,3′ -dideoxyinosine in combination in the absence and presence of ribavirin. Antiviral Chem. Chemother., 5, 403-409.
    • (1994) Antiviral Chem. Chemother. , vol.5 , pp. 403-409
    • Palmer, S.1    Cox, S.2
  • 24
    • 0028875082 scopus 로고
    • Intracellular activation and cytotoxicity of three different combinations of 3′-azido-3′-deoxythymidine and 2′,3′-dideoxyinosine
    • Palmer,S. and Cox,S. (1995) Intracellular activation and cytotoxicity of three different combinations of 3′-azido-3′-deoxythymidine and 2′,3′ -dideoxyinosine. AIDS Res. Hum. Retroviruses, 11, 1227-1233.
    • (1995) AIDS Res. Hum. Retroviruses , vol.11 , pp. 1227-1233
    • Palmer, S.1    Cox, S.2
  • 25
    • 0031779845 scopus 로고    scopus 로고
    • Intracellular phosphorylation of zidovudine (ZDV) and other nucleoside reverse transcriptase inhibitors (RTI) used for human immunodeficiency virus (HIV) infection
    • Peter,K. and Gambertoglio,J.G. (1998) Intracellular phosphorylation of zidovudine (ZDV) and other nucleoside reverse transcriptase inhibitors (RTI) used for human immunodeficiency virus (HIV) infection. Pharm. Res., 15, 819-825.
    • (1998) Pharm. Res. , vol.15 , pp. 819-825
    • Peter, K.1    Gambertoglio, J.G.2
  • 26
    • 0033572374 scopus 로고    scopus 로고
    • Incorporation of 3′-azido-3′-deoxythymidine (AZT) into fetal DNA and fetal tissue distribution of drug after infusion of pregnant late-term rhesus macaques with a human-equivalent AZT dose
    • Poirier,M.C., Patterson,T.A., Slikker,W.,Jr and Olivero,O.A. (1999) Incorporation of 3′-azido-3′-deoxythymidine (AZT) into fetal DNA and fetal tissue distribution of drug after infusion of pregnant late-term rhesus macaques with a human-equivalent AZT dose. J. Acquir. Immune Defic. Syndr., 22, 477-483.
    • (1999) J. Acquir. Immune Defic. Syndr. , vol.22 , pp. 477-483
    • Poirier, M.C.1    Patterson, T.A.2    Slikker Jr., W.3    Olivero, O.A.4
  • 27
    • 0024598357 scopus 로고
    • Comparative pharmacokinetics of new anti-HIV agents: 2′,3′-dideoxyadenosine and 2′,3′-dideoxyinosine
    • Russell,J.W. and Klunk,L.J. (1989) Comparative pharmacokinetics of new anti-HIV agents: 2′,3′ -dideoxyadenosine and 2′,3′-dideoxyinosine. Biochem. Pharmacol., 38, 1385-1388.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 1385-1388
    • Russell, J.W.1    Klunk, L.J.2
  • 28
    • 0024330659 scopus 로고
    • Comparison of Acridine Orange and Giemsa stains in several mouse bone marrow micronucleus assays-including a triple dose study
    • Tinwell,H. and Ashby,J. (1989) Comparison of Acridine Orange and Giemsa stains in several mouse bone marrow micronucleus assays-including a triple dose study. Mutagenesis, 4, 476-481.
    • (1989) Mutagenesis , vol.4 , pp. 476-481
    • Tinwell, H.1    Ashby, J.2
  • 30
    • 0025143813 scopus 로고
    • Incorporation of 3′-azido-3′-deoxythymidine into cellular DNA and its removal in a human leukemic cell line
    • Vazquez-Padua,M.A., Starnes,M.C. and Cheng,Y.-c. (1990) Incorporation of 3′-azido-3′-deoxythymidine into cellular DNA and its removal in a human leukemic cell line. Cancer Commun., 2, 55-62.
    • (1990) Cancer Commun. , vol.2 , pp. 55-62
    • Vazquez-Padua, M.A.1    Starnes, M.C.2    Cheng, Y.-C.3
  • 31
    • 0027939485 scopus 로고
    • Effects of dideoxyinosine and dideoxycytidine on the intracellular phosphorylation of zidovudine in human mononuclear cells
    • Veal,G.J., Wild,M.J., Baffy,M.G. and Back,D.J. (1994) Effects of dideoxyinosine and dideoxycytidine on the intracellular phosphorylation of zidovudine in human mononuclear cells. Br. J. Clin. Pharmacol., 38, 323-328.
    • (1994) Br. J. Clin. Pharmacol. , vol.38 , pp. 323-328
    • Veal, G.J.1    Wild, M.J.2    Baffy, M.G.3    Back, D.J.4
  • 33
    • 0033402830 scopus 로고    scopus 로고
    • Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea
    • Walker,V.E., Jones,I.M., Crippen,T.L., Meng,Q., Walker,D.M., Bauer,M.J., Reilly,A.A., Tates,A.D., Nakamura,J., Upton,P.B. and Skopek,T.R. (1999) Relationships between exposure, cell loss and proliferation, and manifestation of Hprt mutant T cells following treatment of preweanling, weanling, and adult male mice with N-ethyl-N-nitrosourea. Mutat. Res., 431, 371-388.
    • (1999) Mutat. Res. , vol.431 , pp. 371-388
    • Walker, V.E.1    Jones, I.M.2    Crippen, T.L.3    Meng, Q.4    Walker, D.M.5    Bauer, M.J.6    Reilly, A.A.7    Tates, A.D.8    Nakamura, J.9    Upton, P.B.10    Skopek, T.R.11
  • 34
    • 0026539563 scopus 로고
    • Lack of pharmacokinetic interaction between intravenous 2′,3′-dideoxyinosine and 3′-azido-3′ -deoxythymidine in rats
    • Wientjes,M.G. and Au,J.L.-S. (1992) Lack of pharmacokinetic interaction between intravenous 2′,3′-dideoxyinosine and 3′-azido-3′-deoxythymidine in rats. Antimicrob. Agents Chemother., 36, 665-668.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 665-668
    • Wientjes, M.G.1    Au, J.L.-S.2
  • 35
    • 0242664024 scopus 로고    scopus 로고
    • Liquid chromatographic-mass spectrometric determination of the metabolism and disposition of the anti-retroviral nucleoside analogs zidovudine and lamivudine in C57BL/6N and B6C3F1 mice
    • Williams,L.D., Von Tungeln,L.S., Beland,F.A. and Doerge,D.R. (2003) Liquid chromatographic-mass spectrometric determination of the metabolism and disposition of the anti-retroviral nucleoside analogs zidovudine and lamivudine in C57BL/6N and B6C3F1 mice. J. Chromatogr., 798, 55-62.
    • (2003) J. Chromatogr. , vol.798 , pp. 55-62
    • Williams, L.D.1    Von Tungeln, L.S.2    Beland, F.A.3    Doerge, D.R.4
  • 36
    • 0027057407 scopus 로고
    • Adjusted P-values for simultaneous inference
    • Wright,S.P. (1992) Adjusted P-values for simultaneous inference. Biometrics, 48, 1005-1013.
    • (1992) Biometrics , vol.48 , pp. 1005-1013
    • Wright, S.P.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.