Initiation of cellular organization in lymph nodes is regulated by non-B cell-derived signals and is not dependent on CXC chemokine ligand 13

Journal of Immunology

Volumn 173, Issue 8, 2004, Pages 4889-4896

  Cupedo, Tom ^a   Lund, Frances E ^b   Ngo, Vu N ^c   Randall, Troy D ^b   Jansen, Wendy ^a   Greuter, Mascha J ^a   De Waal Malefyt, Rene ^d   Kraal, Georg ^a   Cyster, Jason G ^c   Mebius, Reina E ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b TRUDEAU INSTITUTE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA CHEMOKINE; CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; LIGAND; LYMPHOTOXIN; LYMPHOTOXIN BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL MIGRATION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; GENE EXPRESSION; LYMPH FOLLICLE; LYMPH NODE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INDUCTION; SIGNAL TRANSDUCTION; T LYMPHOCYTE;

EID: 6344284241     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.8.4889     Document Type: Article

References (44)

1. MacLennan, I. C. 1994. Germinal centers. Annu. Rev. Immunol. 12:117.
2. Kelsoe, G. 1996. Life and death in germinal centers (redux). Immunity 4:107.
3. Kelsoe, G., and B. Zheng. 1993. Sites of B-cell activation in vivo. Curr. Opin. Immunol. 5:418.
4. Tarlinton, D. 1998. Germinal centers: form and function. Curr. Opin. Immunol. 10:245.
5. Tarlinton, D. M., and K. G. Smith. 2000. Dissecting affinity maturation: a model explaining selection of antibody-forming cells and memory B cells in the germinal centre. Immunol. Today 21:436.
6. Endres, R., M. B. Alimzhanov, T. Plitz, A. Fütterer, M. H. Kosco-Vilbois, S. A. Nedospasov, K. Rajewsky, and K. Pfeffer. 1999. Mature follicular dendritic cell networks depend on expression of lymphotoxin β receptor by radioresistant stromal cells and of lymphotoxin β and tumor necrosis factor by B cells. J. Exp. Med. 189:159.
7. Ettinger, R., J. L. Browning, S. A. Michie, W. van Ewijk, and H. O. McDevitt. 1996. Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-β receptor-IgG1 fusion protein. Proc. Natl. Acad. Sci. USA 93:13102.
8. Banks, T. A., B. T. Rouse, M. K. Kerley, P. J. Blair, V. L. Godfrey, N. A. Kuklin, D. M. Bouley, J. Thomas, S. Kanangat, and M. L. Mucenski. 1995. Lymphotoxin-α-deficient mice: effects on secondary lymphoid organ development and humoral immune responsiveness. J. Immunol. 155:1685.
9. Alimzhanov, M. B., D. V. Kuprash, M. H. Kosco-Vilbois, A. Luz, R. L. Turetskaya, A. Tarakhovsky, K. Rajewsky, S. A. Nedospasov, and K. Pfeffer. 1997. Abnormal development of secondary lymphoid tissues in lymphotoxin β-deficient mice. Proc. Natl. Acad. Sci. USA 94:9302.
10. Futterer, A., K. Mink, A. Luz, M. H. Kosco-Vilbois, and K. Pfeffer. 1998. The lymphotoxin β receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 9:59.
11. Körner, H., M. Cook, D. S. Riminton, F. A. Lemckert, R. M. Hoek, B. Ledermann, F. Königen, B. Fazekas de St. Groth, and J. D. Sedgwick. 1997. Distinct roles for lymphotoxin-α and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue. Eur. J. Immunol. 27:2600.
12. Togni, P. d., J. Goellner, N. H. Ruddle, P. R. Streeter, A. Fick, S. Mariathasan, S. C. Smith, R. Carlson, L. P. Shornick, J. Strauss-Schoenberger, et al. 1994. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 264:703.
13. Pasparakis, M., L. Alexopoulou, M. Grell, K. Pfizenmaier, H. Bluethmann, and G. Kollias. 1997. Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor. Proc. Natl. Acad. Sci. USA 94:6319.
14. Ettinger, R., R. Mebius, J. L. Browning, S. A. Michie, S. van Tuijl, G. Kraal, W. van Ewijk, and H. O. McDevitt. 1998. Effects of tumor necrosis factor and lymphotoxin on peripheral lymphoid tissue development. Int. Immunol. 10:727.
15. Rennert, P. D., J. L. Browning, R. Mebius, F. Mackay, and P. S. Hochman. 1996. Surface lymphotoxin α/β complex is required for the development of peripheral lymphoid organs. J. Exp. Med. 184:1999.
16. Rennert, P. D., D. James, F. Mackay, J. L. Browning, and P. S. Hochman. 1998. Lymph node genesis is induced by signaling through the lymphotoxin β receptor. Immunity 9:71.
17. Fu, Y. X., and D. D. Chaplin. 1999. Development and maturation of secondary lymphoid tissues. Annu. Rev. Immunol. 17:399.
18. Miyawaki, S., Y. Nakamura, H. Suzuka, M. Koba, R. Yasumizu, S. Ikehara, and Y. Shibata. 1994. A new mutation, aly, that induces a generalized lack of lymph nodes accompanied by immunodeficiency in mice. Eur. J. Immunol. 24:429.
19. Fu, Y. X., G. Huang, Y. Wang, and D. D. Chaplin. 1998. B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin α-dependent fashion. J. Exp. Med. 187:1009.
20. Gonzalez, M., F. Mackay, J. L. Browning, M. H. Kosco-Vilbois, and R. J. Noelle. 1998. The sequential role of lymphotoxin and B cells in the development of splenic follicles. J. Exp. Med. 187:997.
21. Ansel, K. M., V. N. Ngo, P. L. Hyman, S. A. Luther, R. Förster, J. Sedgwick, J. L. Browning, M. Lipp, and J. G. Cyster. 2000. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 406:309.
22. Tumanov, A., D. Kuprash, M. Lagarkova, S. Grivennikov, K. Abe, A. Shakhov, L. Drutskaya, C. Stewart, A. Chervonsky, and S. Nedospasov. 2002. Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues. Immunity 17:239.
23. Ngo, V. N., H. Korner, M. D. Gunn, K. N. Schmidt, D. S. Riminton, M. D. Cooper, J. L. Browning, J. D. Sedgwick, and J. G. Cyster. 1999. Lymphotoxin α/β and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J. Exp. Med. 189:403.
24. Friedberg, S. H., and I. L. Weissman. 1974. Lymphoid tissue architecture. II. Ontogeny of peripheral T and B cells in mice: evidence against Peyer's patches as the site of generation of B cells. J. Immunol. 113:1477.
25. - cells to colonize lymph nodes. Proc. Natl. Acad. Sci. USA 93:11019.
26. Forster, R., A. E. Mattis, E. Kremmer, E. Wolf, G. Brem, and M. Lipp. 1996. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 87:1037.
27. + cells. Immunity 17:31.
28. 1 integrin activation by CXCR5. Immunity 17:363.
29. t in the generation of fetal lymphoid tissue inducer cells. Nat. Immunol. 5:64.
30. - cells in lymphoid organ development. Immunol. Rev. 189:41.
31. Mebius, R. E. 2003. Organogenesis of lymphoid tissues. Nat. Rev. Immunol. 3:292.
32. + cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells. Immunity 7:493.
33. Kim, D., R. E. Mebius, J. D. MacMicking, S. Jung, T. Cupedo, Y. Castellanos, J. Rho, B. R. Wong, R. Josien, N. Kim, et al. 2000. Regulation of peripheral lymph node genesis by the tumor necrosis factor family member TRANCE. J. Exp. Med. 192:1467.
34. Honda, K., H. Nakano, H. Yoshida, S. Nishikawa, P. Rennert, K. Ikuta, M. Tamechika, K. Yamaguchi, T. Fukumoto, T. Chiba, et al. 2001. Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis. J. Exp. Med. 193:621.
35. Fu, Y.-X., G. Huang, M. Matsumoto, H. Molina, and D. D. Chaplin. 1997. Independent signals regulate development of primary and secondary follicle structure in spleen and mesenteric lymph node. Proc. Natl. Acad. Sci. USA 94:5739.
36. Ruddle, N. H. 1999. Lymphoid neo-organogenesis: lymphotoxin's role in inflammation and development. Immunol. Res. 19:119.
37. Salomonsson, S., P. Larsson, P. Tengner, E. Mellquist, P. Hjelmstrom, and M. Wahren-Herlenius. 2002. Expression of the B cell-attracting chemokine CXCL13 in the target organ and autoantibody production in ectopic lymphoid tissue in the chronic inflammatory disease Sjogren's syndrome. Scand. J. Immunol. 55:336.
38. Weyand, C. M., P. J. Kurtin, and J. J. Goronzy. 2001. Ectopic lymphoid organogenesis: a fast track for autoimmunity. Am. J. Pathol. 159:787.
39. Shi, K., K. Hayashida, M. Kaneko, J. Hashimoto, T. Tomita, P. E. Lipsky, H. Yoshikawa, and T. Ochi. 2001. Lymphoid chemokine B cell-attracting chemokine-1 (CXCL13) is expressed in germinal center of ectopic lymphoid follicles within the synovium of chronic arthritis patients. J. Immunol. 166:650.
40. Hjelmstrom, P. 2001. Lymphoid neogenesis: de novo formation of lymphoid tissue in chronic inflammation through expression of homing chemokines. J. Leukocyte Biol. 69:331.
41. Amft, N., S. J. Curnow, D. Scheel-Toellner, A. Devadas, J. Oates, J. Crocker, J. Hamburger, J. Ainsworth, J. Mathews, M. Salmon, et al. 2001. Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjogren's syndrome. Arthritis Rheum. 44:2633.
42. Hjelmstrom, P., J. Fjell, T. Nakagawa, R. Sacca, C. A. Cuff, and N. H. Ruddle. 2000. Lymphoid tissue horning chemokines are expressed in chronic inflammation. Am. J. Pathol. 156:1133.
43. Nishikawa, S. I., H. Hashi, K. Honda, S. Fraser, and H. Yoshida. 2000. Inflammation, a prototype for organogenesis of the lymphopoietic/hematopoietic system. Curr. Opin. Immunol. 12:342.
44. Cupedo, T., and R. E. Mebius. 2003. Role of chemokines in the development of secondary and tertiary lymphoid tissues. Semin. Immunol. 15:243.