The role of CD45+CD4+CD3- cells in lymphoid organ development

Immunological Reviews

Volumn 189, Issue , 2002, Pages 41-50

  Cupedo, Tom ^a   Kraal, Georg ^a   Mebius, Reina E ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CARRIER PROTEIN; MEMBRANE PROTEIN; OSTEOCLAST DIFFERENTIATION FACTOR; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR KAPPA B; TNFRSF11A PROTEIN, HUMAN; TNFRSF11A PROTEIN, MOUSE; TNFSF11 PROTEIN, HUMAN; TNFSF11 PROTEIN, MOUSE;

BONE MARROW CELL; CELL DIFFERENTIATION; CELLULAR DISTRIBUTION; FETUS; GENE FUNCTION; HEMATOPOIETIC CELL; LYMPH NODE; LYMPHATIC SYSTEM; LYMPHOID ORGAN; LYMPHOPOIESIS; MESENTERY LYMPH NODE; MOUSE; NONHUMAN; PEYER PATCH; PRIORITY JOURNAL; REVIEW; STEM CELL; ANIMAL; BIOLOGICAL MODEL; CD4+ T LYMPHOCYTE; CYTOLOGY; GENE EXPRESSION REGULATION; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; LIVER; METABOLISM; MOUSE MUTANT; PRENATAL DEVELOPMENT; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; ANTIGENS, CD3; ANTIGENS, CD45; CARRIER PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; FETUS; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HUMANS; LIVER; LYMPH NODES; LYMPHATIC SYSTEM; MEMBRANE GLYCOPROTEINS; MICE; MICE, MUTANT STRAINS; MODELS, IMMUNOLOGICAL; PEYER'S PATCHES; RANK LIGAND; RECEPTOR ACTIVATOR OF NUCLEAR FACTOR-KAPPA B; T-LYMPHOCYTE SUBSETS;

EID: 0036863612     PISSN: 01052896     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-065X.2002.18905.x     Document Type: Review

References (75)

1. Sabin FR. The lymphatic system in human embryos, with a consideration of the morphology of the system as a whole. Am J Anat 1909;9:43-91.
2. Sabin FR. On the origin of the lymphatic system from the veins and the development of the lymph hearts and thoracic ducts in the pig. Am J Anat 1902;1:367-389.
3. Eikelenboom P, Nassy JJ, Post J, Versteeg JC, Langevoort HL. The histogenesis of lymph nodes in rat and rabbit. Anat Rec 1978;190:201-215.
4. Bailey RP, Weiss L. Ontogeny of human fetal lymph nodes. Am J Anat 1975;142:15-27.
5. Sabin FR. On the development of the superficial lymphatics in the skin of the pig. Am J Anat 1904;3:183-195.
6. Sabin FR. Further evidence on the origin of the lymphatic endothelium from the endothelium of the blood vascular system. Anat Rec 1908;2:46-55.
7. Wigle JT, Oliver G. Prox 1 function is required for the development of the murine lymphatic system. Cell 1999;98:769-778.
8. Wigle JT, et al. An essential role for Prox 1 in the induction of the lymphatic endothelial cell phenotype. EMBO J 2002;21:1505-1513.
9. Nakano H, Gunn MD. Gene duplications at the chemokine locus on mouse chromosome 4: Multiple strain-specific haplotypes and the deletion of secondary lymphoid-organ chemokine and EBI-1 ligand chemokine genes in the pit mutation. J Immunol 2001;166:361-369.
10. Kaipainen A, et al. Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci USA 1995;92:3566-3570.
11. Banerji S, et al. LYVE-1, a new homologue of the CD44 glycoprotein, is a lymph-specific receptor for hyaluronan. J Cell Biol 1999;144:789-801.
12. De Togni P, et al. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science 1994;264:703-707.
13. Banks TA, et al. Lymphotoxin-α-deficient mice. Effects on secondary lymphoid organ development and humoral immune responsiveness. J Immunol 1995;155:1685-1693.
14. Ruddle NH. Tumor necrosis factor (TNF-α) and lymphotoxin (TNF-β). Curr Opin Immunol 1992;4:327-332.
15. Ware CF, VanArsdale TL, Crowe PD, Browning JL. The ligands and receptors of the lymphotoxin system. Curr Top Microbiol Immunol 1995;198:175-218.
16. Pasparakis M, Alexopoulou L, Grell M, Pfizenmaier K, Bluethmann H, Kollias G. Peyer's patch organogenesis is intact yet formation of B lymphocyte follicles is defective in peripheral lymphoid organs of mice deficient for tumor necrosis factor and its 55-kDa receptor. Proc Natl Acad Sci USA 1997;94:6319-6323.
17. Erickson S, et al. Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice. Nature 1994:372:560-563.
18. Rothe J, et al. Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenes. Nature 1993;364:798-802.
19. Pfeffer K, et al. Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infection. Cell 1993;73:457-467.
20. Koni PA, Sacca R, Lawton P, Browning JL, Ruddle NH, Flavell RA. Distinct roles in lymphoid organogenesis for lymphotoxins α?and β?revealed in lymphotoxins β-deficient mice. Immunity 1997;6:491-500.
21. Futterer A, Mink K, Luz A, Kosco-Vilbois MH, Pfeffer K. The lymphotoxins β receptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity 1998;9:59-70.
22. Alimzhanov MB, et al. Abnormal development of secondary lymphoid tissues in lymphotoxins β-deficient mice. Proc Natl Acad Sci USA 1997;94:9302-9307.
23. Shinkura R, et al. Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase. Nat Genet 1999;22:74-77.
24. Yin L, Wu L, et al. Defective lymphotoxins-β receptor-induced NF-κB transcriptional activity in NIK-deficient mice. Science 2001;291:2162-2165.
25. Smith C, Andreakos E, Crawley JB, Brennan FM, Feldmann FN, Foxwell BM. NF-κB-inducing kinase is dispensable for activation of NF-κB in inflammatory settings but essential for lymphotoxin β receptor activation of NF-κB in primary human fibroblasts. J Immunol 2001;167:5895-5903.
26. Matsushima A, et al. Essential role of nuclear factor (NF) -κB-inducing kinase and inhibitor of κB (IκB) kinase α in NF-κB activation through lymphotoxins β receptor, but not through tumor necrosis factor receptor I. J Exp Med 2001;193:631-636.
27. Rennert PD, Browning JL, Mebius R, Mackay F, Hochman PS. Surface lymphotoxins α/β complex is required for the development of peripheral lymphoid organs. J Exp Med 1996;184:1999-2006.
28. Koni PA, Flavell RA. A role for tumor necrosis factor receptor type 1 in gut-associated lymphoid tissue development. genetic evidence of synergism with lymphotoxins β. J Exp Med 1998;187:1977-1983.
29. Rennert PD, James D, Mackay F, Browning JL, Hochman PS. Lymph node genesis is induced by signaling through the lymphotoxin β receptor. Immunity 1998;9:71-79.
30. Scheu S, Alferink J, Potzel T, Barchet W, Kalinke U, Pfeffer K. Targeted disruption of LIGHT causes defects in costimulatory T cell activation and reveals cooperation with lymphotoxins β in mesenteric lymph node genesis. J Exp Med 2002;195:1613-1624.
31. Kratz A, Campos-Neto A, Hanson MS, Ruddle NH. Chronic inflammation caused by lymphotoxins is lymphoid neogenesis. J Exp Med 1996;183:1461-1472.
32. + cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells. Immunity 1997;7:493-504.
33. - cells, as well as macrophages. J Immunol 2001;166:6593-6601.
34. - cells to colonize lymph nodes. Proc Natl Acad Sci USA 1996;93:11019-11024.
35. Kondo M, Weissman IL, Akashi K. Identification of clonogenic common lymphoid progenitors in mouse bone marrow. Cell 1997;91:661-672.
36. Sun Z, et al. Requirement for RORγ in thymocyte survival and lymphoid organ development. Science 2000:288:2369-2373.
37. Kurebayashi S, et al. Retinoid-related orphan receptor γ (RORγ) is essential for lymphoid organogenesis and controls apoptosis during thymopoiesis. Proc Natl Acad Sci USA 2000;97:10132-10137.
38. Yokota Y, et al. Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature 1999;397:702-706.
39. Dougall WC, et al. RANK is essential for osteoclast and lymph node development. Genes Dev 1999;13:2412-2424.
40. Kong YY, et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 1999;397:315-323.
41. Kim D, et al. Regulation of peripheral lymph node genesis by the tumor necrosis factor family member TRANCE. J Exp Med 2000;192:1467-1478.
42. Anderson DM, et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 1997;390:175-179.
43. Nakagawa N, et al. RANK is the essential signaling receptor for osteoclast differentiation factor in osteoclastogenesis. Biochem Biophys Res Commun 1998;253:395-400.
44. Burgess TL, et al. The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts. J Cell Biol 1999;145:527-538.
45. Hsu H, et al. Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand. Proc Natl Acad Sci USA 1999;96:3540-3545.
46. Naito A, et al. Severe osteopetrosis, defective interleukin-1 signalling and lymph node organogenesis in TRAF6-deficient mice. Genes Cells 1999;4:353-362.
47. Yoshida H, et al. Expression of a (4) β (7) integrin defines a distinct pathway of lymphoid progenitors committed to T cells, fetal intestinal lymphotoxins producer, NK, and dendritic cells. J Immunol 2001;167:2511-2521.
48. Georgopoulos K, et al. The Ikaros gene is required for the development of all lymphoid lineages. Cell 1994;79:143-156.
49. Wang JH, et al. Selective defects in the development of the fetal and adult lymphoid system in mice with an Ikaros null mutation. Immunity 1996;5:537-549.
50. Adachi S, Yoshida H, Kataoka H, Nishikawa S. Three distinctive steps in Peyer's patch formation of murine embryo. Int Immunol 1997;9:507-514.
51. Adachi S, et al. Essential role of IL-7 receptor α in the formation of Peyer's patch anlage. Int Immunol 1998;10:1-6.
52. - cells in the embryonic intestine induces the organizing center of Peyer's patches. Int Immunol 1999;11:643-655.
53. Honda K, et al. Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis. J Exp Med 2001;193:621-630.
54. Cuff CA, Schwartz J, Bergman CM, Russell KS, Bender JR, Ruddle NH. Lymphotoxin α3 induces chemokines and adhesion molecules: insight into the role of LT α in inflammation and lymphoid organ development. J Immunol 1998;161:6853-6860.
55. Cuff CA, Sacca R, Ruddle NH. Differential induction of adhesion molecule and chemokine expression by LTα3 and LTαβ in inflammation elucidates potential mechanisms of mesenteric and peripheral lymph node development. J Immunol 1999;162:5965-5972.
56. Ngo VN, et al. Lymphotoxin α/β and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J Exp Med 1999;189:403-412.
57. Degli-Esposti MA, Davis-Smith T, Din WS, Smolak PJ, Goodwin RG, Smith CA. Activation of the lymphotoxin β receptor by cross-linking induces chemokine production and growth arrest in A375 melanoma cells. J Immunol 1997;158:1756-1762.
58. Ansel KM, et al. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature 2000;406:309-314.
59. Forster R, Mattis AE, Kremmer E, Wolf E, Brem G, Lipp M. A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen. Cell 1996;87:1037-1047.
60. Gunn MD, Ngo VN, Ansel KM, Ekland EH, Cyster JG, williams LY. A B-cell-homing chemokine made in lymphoid follicles activates Burkitt's lymphoma receptor-1. Nature 1998;391:799-803.
61. Luther SA, Lopez T, Bai W, Hanahan D, Cyster JG. BLC expression in pancreatic islets causes B cell recruitment and lymphotoxins-dependent lymphoid neogenesis. Immunity 2000;12:471-481.
62. Luther SA, et al. Differing activities of homeostatic chemokines CCL19, CCL21, and CXCL12 in lymphocyte and dendritic cell recruitment and lymphoid neogenesis. J Immunol 2002;169:424-433.
63. Fan L, Reilly CR, Luo Y, Dorf ME, Lo D. Cutting edge: Ectopic expression of the chemokine TCA4/SLC is sufficient to trigger lymphoid neogenesis. J Immunol 2000;164:3955-3959.
64. Nakano H, et al. Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes. Eur J Immunol 1997;27:215-221.
65. Gunn MD, et al. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J Exp Med 1999;189:451-460.
66. Vassileva G, et al. The reduced expression of 6Ckine in the plt mouse results from the deletion of one of two 6Ckine genes. J Exp Med 1999;190:1183-1188.
67. Luther SA, Tang HL, Hyman PL, Farr AG, Cyster JG. Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse. Proc Natl Acad Sci USA 2000;97:12694-12699.
68. Forster R, et al. CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs. Cell 1999;99:23-33.
69. Matsumoto M, et al. Involvement of distinct cellular compartments in the abnormal lymphoid organogenesis in lymphotoxin-α-deficient mice and alymphoplasia (aly) mice defined by the chimeric analysis. J Immunol 1999;163:1584-1591.
70. Amft N, et al. Ectopic expression of the B cell-attracting chemokine BCA-1 (CXCL13) on endothelial cells and within lymphoid follicles contributes to the establishment of germinal center-like structures in Sjogren's syndrome. Arthritis Rheum 2001;44:2633-2641.
71. Hjelmstrom P. Lymphoid neogenesis: De novo formation of lymphoid tissue in chronic inflammation through expression of homing chemokines. J Leukoc Biol 2001;69:331-339.
72. Kang YM, et al. CD8 T cells are required for the formation of ectopic germinal centers in rheumatoid synovitis. J Exp Med 2002;195:1325-1336.
73. Takemura S, et al. Lymphoid neogenesis in rheumatoid synovitis. J Immunol 2001;167:1072-1080.
74. Salomonsson S, Larsson P, Tengner P, Mellquist E, Hjelmstrom P, Wahren-Herlenius M. Expression of the B cell-attracting chemokine CXCL13 in the target organ and autoantibody production in ectopic lymphoid tissue in the chronic inflammatory disease Sjogren's syndrome. Scand J Immunol 2002;55:336-342.
75. Nishikawa SI, Hashi H, Honda K, Fraser S, Yoshida H. Inflammation, a prototype for organogenesis of the lymphopoietic/hematopoietic system. Curr Opin Immunol 2000;12:342-345.