Distinct role of surface lymphotoxin expressed by B cells in the organization of secondary lymphoid tissues

Immunity

Volumn 17, Issue 3, 2002, Pages 239-250

  Tumanov, Alexei V ^a,b,c   Kuprash, Dmitry V ^a   Lagarkova, Maria A ^a   Grivennikov, Sergei I ^a   Abe, Koichiro ^b   Shakhov, Alexander N ^b   Drutskaya, Ludmila N ^b   Stewart, Colin L ^b   Chervonsky, Alexander V ^c   Nedospasov, Sergei A ^a,b  

^a ENGELHARDT INSTITUTE OF MOLECULAR BIOLOGY   (Russian Federation)

^b NATIONAL CANCER INSTITUTE   (United States)

^c JACKSON LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; LYMPHOTOXIN; TRANSFORMING GROWTH FACTOR;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; CELL COUNT; CONTROLLED STUDY; DENDRITIC CELL; ERYTHROCYTE; GENE DELETION; KNOCKOUT MOUSE; LYMPH NODE; LYMPHOID TISSUE; MOLECULAR BIOLOGY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PEYER PATCH; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SHEEP; SPLEEN; SURFACE PROPERTY;

EID: 18644366772     PISSN: 10747613     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-7613(02)00397-7     Document Type: Article

References (67)

1. Alimzhanov M.B., Kuprash D.V., Kosco-Vilbois M.H., Luz A., Turetskaya R.L., Tarakhovsky A., Rajewsky K., Nedospasov S.A., Pfeffer K. Abnormal development of secondary lymphoid tissues in lymphotoxin beta-deficient mice. Proc. Natl. Acad. Sci. USA. 94:1997;9302-9307.
2. Ansel K.M., Ngo V.N., Hyman P.L., Luther S.A., Forster R., Sedgwick J.D., Browning J.L., Lipp M., Cyster J.G. A chemokine-driven positive feedback loop organizes lymphoid follicles. Nature. 406:2000;309-314.
3. Bergmann C.C., Ramakrishna C., Kornacki M., Stohlman S.A. Impaired T cell immunity in B cell-deficient mice following viral central nervous system infection. J. Immunol. 167:2001;1575-1583.
4. Browning J.L., Ngam-ek A., Lawton P., DeMarinis J., Tizard R., Chow E.P., Hession C., O'Brine-Greco B., Foley S.F., Ware C.F. Lymphotoxin β, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surface. Cell. 72:1993;847-856.
5. Browning J.L., Dougas I., Ngam-ek A., Bourdon P.R., Ehrenfels B.N., Miatkowski K., Zafari M., Yampaglia A.M., Lawton P., Meier W. Characterization of surface lymphotoxin forms. Use of specific monoclonal antibodies and soluble receptors. J. Immunol. 154:1995;33-46.
6. Crowe P.D., VanArsdale T.L., Walter B.N., Ware C.F., Hession C., Ehrenfels B., Browning J.L., Din W.S., Goodwin R.G., Smith C.A. A lymphotoxin-beta-specific receptor. Science. 264:1994;707-710.
7. Cyster J.G. Chemokines and the homing of dendritic cells to the T cell areas of lymphoid organs. J. Exp. Med. 189:1999;447-450.
8. Cyster J.G., Ansel K.M., Reif K., Ekland E.H., Hyman P.L., Tang H.L., Luther S.A., Ngo V.N. Follicular stromal cells and lymphocyte homing to follicles. Immunol. Rev. 176:2000;181-193.
9. De Togni P., Goellner J., Ruddle N.H., Streeter P.R., Fick A., Mariathasan S., Smith S.C., Carlson R., Shornick L.P., Strauss-Schoenberger J.et al. Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxin. Science. 264:1994;703-707.
10. Debard N., Sierro F., Browning J., Kraehenbuhl J.P. Effect of mature lymphocytes and lymphotoxin on the development of the follicle-associated epithelium and M cells in mouse Peyer's patches. Gastroenterology. 120:2001;1173-1182.
11. Dohi T., Rennert P.D., Fujihashi K., Kiyono H., Shirai Y., Kawamura Y.I., Browning J.L., McGhee J.R. Elimination of colonic patches with lymphotoxin beta receptor-Ig prevents Th2 cell-type colitis. J. Immunol. 167:2001;2781-2790.
12. Endres R., Alimzhanov M.B., Plitz T., Futterer A., Kosco-Vilbois M.H., Nedospasov S.A., Rajewsky K., Pfeffer K. Mature follicular dendritic cell networks depend on expression of lymphotoxin beta receptor by radioresistant stromal cells and of lymphotoxin beta and tumor necrosis factor by B cells. J. Exp. Med. 189:1999;159-168.
13. Ettinger R., Mebius R., Browning J.L., Michie S.A., van Tuijl S., Kraal G., van Ewijk W., McDevitt H.O. Effects of tumor necrosis factor and lymphotoxin on peripheral lymphoid tissue development. Int. Immunol. 10:1998;727-741.
14. Fu Y.X., Chaplin D.D. Development and maturation of secondary lymphoid tissues. Annu. Rev. Immunol. 17:1999;399-433.
15. Fu Y.X., Huang G., Matsumoto M., Molina H., Chaplin D.D. Independent signals regulate development of primary and secondary follicle structure in spleen and mesenteric lymph node. Proc. Natl. Acad. Sci. USA. 94:1997;5739-5743.
16. Fu Y.X., Huang G., Wang Y., Chaplin D.D. B lymphocytes induce the formation of follicular dendritic cell clusters in a lymphotoxin alpha-dependent fashion. J. Exp. Med. 187:1998;1009-1018.
17. Fu Y.X., Huang G., Wang Y., Chaplin D.D. Lymphotoxin-alpha-dependent spleen microenvironment supports the generation of memory B cells and is required for their subsequent antigen-induced activation. J. Immunol. 164:2000;2508-2514.
18. Futterer A., Mink K., Luz A., Kosco-Vilbois M.H., Pfeffer K. The lymphotoxin βreceptor controls organogenesis and affinity maturation in peripheral lymphoid tissues. Immunity. 9:1998;59-70.
19. Golovkina T.V., Shlomchik M., Hannum L., Chervonsky A. Organogenic role of B lymphocytes in mucosal immunity. Science. 286:1999;1965-1968.
20. Gonzalez M., Mackay F., Browning J.L., Kosco-Vilbois M.H., Noelle R.J. The sequential role of lymphotoxin and B cells in the development of splenic follicles. J. Exp. Med. 187:1998;997-1007.
21. Gunn M.D., Kyuwa S., Tam C., Kakiuchi T., Matsuzawa A., Williams L.T., Nakano H. Mice lacking expression of secondary lymphoid organ chemokine have defects in lymphocyte homing and dendritic cell localization. J. Exp. Med. 189:1999;451-460.
22. Guo Z., Wang J., Meng L., Wu Q., Kim O., Hart J., He G., Zhou P., Thistlethwaite J.R.J., Alegre M.L.et al. Cutting edge. membrane lymphotoxin regulates CD8(+) T cell-mediated intestinal allograft rejection J. Immunol. 167:2001;4796-4800.
23. Hasbold J., Johnson-Leger C., Atkins C.J., Clark E.A., Klaus G.G. Properties of mouse CD40. cellular distribution of CD40 and B cell activation by monoclonal anti-mouse CD40 antibodies Eur. J. Immunol. 24:1994;1835-1842.
24. Homann D., Tishon A., Berger D.P., Weigle W.O., von Herrath M.G., Oldstone M.B. Evidence for an underlying CD4 helper and CD8 T-cell defect in B-cell-deficient mice. failure to clear persistent virus infection after adoptive immunotherapy with virus-specific memory cells from muMT/muMT mice J. Virol. 72:1998;9208-9216.
25. Honda K., Nakano H., Yoshida H., Nishikawa S., Rennert P., Ikuta K., Tamechika M., Yamaguchi K., Fukumoto T., Chiba T., Nishikawa S.I. Molecular basis for hematopoietic/mesenchymal interaction during initiation of Peyer's patch organogenesis. J. Exp. Med. 193:2001;621-630.
26. Kapasi Z.F., Burton G.F., Shultz L.D., Tew J.G., Szakal A.K. Induction of functional follicular dendritic cell development in severe combined immunodeficiency mice. Influence of B and T cells. J. Immunol. 150:1993;2648-2658.
27. Koni P.A., Sacca R., Lawton P., Browning J.L., Ruddle N.H., Flavell R.A. Distinct roles in lymphoid organogenesis for lymphotoxins α and β revealed in lymphotoxin β-deficient mice. Immunity. 6:1997;491-500.
28. Korner H., Cook M., Riminton D.S., Lemckert F.A., Hoek R.M., Ledermann B., Kontgen F., Fazekas de St Groth B., Sedgwick J.D. Distinct roles for lymphotoxin-alpha and tumor necrosis factor in organogenesis and spatial organization of lymphoid tissue. Eur. J. Immunol. 27:1997;2600-2609.
29. Kosco M.H., Pflugfelder E., Gray D. Follicular dendritic cell-dependent adhesion and proliferation of B cells in vitro. J. Immunol. 148:1992;2331-2339.
30. Kraal G. Cells in the marginal zone of the spleen. Int. Rev. Cytol. 132:1992;31-74.
31. Kraal G., Janse M. Marginal metallophilic cells of the mouse spleen identified by a monoclonal antibody. Immunology. 58:1986;665-669.
32. Kraal G., Schornagel K., Streeter P.R., Holzmann B., Butcher E.C. Expression of the mucosal vascular addressin, MAdCAM-1, on sinus-lining cells in the spleen. Am. J. Pathol. 147:1995;763-771.
33. Kratz A., Campos-Neto A., Hanson M.S., Ruddle N.H. Chronic inflammation caused by lymphotoxin is lymphoid neogenesis. J. Exp. Med. 183:1996;1461-1472.
34. Kuprash D.V., Alimzhanov M.B., Tumanov A., Anderson A.O., Pfeffer K., Nedospasov S.A. TNF and lymphotoxin beta cooperate in the maintenance of secondary lymphoid tissue microarchitecture but not in the development of lymph nodes. J. Immunol. 163:1999;6575-6580.
35. Le Hir M., Bluethmann H., Kosco-Vilbois M.H., Muller M., di Padova F., Moore M., Ryffel B., Eugster H.P. Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling. J. Exp. Med. 183:1996;2367-2372.
36. Lewandoski M. Conditional control of gene expression in the mouse. Nat. Rev. Genet. 2:2001;743-755.
37. Locksley R.M., Killeen N., Lenardo M.J. The TNF and TNF receptor superfamilies. integrating mammalian biology Cell. 104:2001;487-501.
38. Luther S.A., Lopez T., Bai W., Hanahan D., Cyster J.G. BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis. Immunity. 12:2000;471-481.
39. Mackay F., Browning J.L. Turning off follicular dendritic cells. Nature. 395:1998;26-27.
40. Mackay F., Browning J.L., Lawton P., Shah S.A., Comiskey M., Bhan A.K., Mizoguchi E., Terhorst C., Simpson S.J. Both the lymphotoxin and tumor necrosis factor pathways are involved in experimental murine models of colitis. Gastroenterology. 115:1998;1464-1475.
41. Mebius R.E., Rennert P., Weissman I.L. Developing lymph nodes collect CD4+CD3- LTβ+ cells that can differentiate to APC, NK cells, and follicular cells but not T or B cells. Immunity. 7:1997;493-504.
42. Montrasio F., Frigg R., Glatzel M., Klein M.A., Mackay F., Aguzzi A., Weissmann C. Impaired prion replication in spleens of mice lacking functional follicular dendritic cells. Science. 288:2000;1257-1259.
43. Murphy M., Walter B.N., Pike-Nobile L., Fanger N.A., Guyre P.M., Browning J.L., Ware C.F., Epstein L.B. Expression of the lymphotoxin beta receptor on follicular stromal cells in human lymphoid tissues. Cell Death Differ. 5:1998;497-505.
44. Ngo V.N., Korner H., Gunn M.D., Schmidt K.N., Sean R.D., Cooper M.D., Browning J.L., Sedgwick J.D., Cyster J.G. Lymphotoxin alpha/beta and tumor necrosis factor are required for stromal cell expression of homing chemokines in B and T cell areas of the spleen. J. Exp. Med. 189:1999;403-412.
45. Ngo V.N., Cornall R.J., Cyster J.G. Splenic T zone development is B cell dependent. J. Exp. Med. 194:2001;1649-1660.
46. Pasparakis M., Alexopoulou L., Episkopou V., Kollias G. Immune and inflammatory responses in TNF alpha-deficient mice. a critical requirement for TNF alpha in the formation of primary B cell follicles, follicular dendritic cell networks and germinal centers, and in the maturation of the humoral immune response J. Exp. Med. 184:1996;1397-1411.
47. Pokholok D.K., Maroulakou I.G., Kuprash D.V., Alimzhanov M.B., Kozlov S.V., Novobrantseva T.I., Turetskaya R.L., Green J.E., Nedospasov S.A. Cloning and expression analysis of the murine lymphotoxin beta gene. Proc. Natl. Acad. Sci. USA. 92:1995;674-678.
48. Poudrier J., Weng X., Kay D.G., Pare G., Calvo E.L., Hanna Z., Kosco-Vilbois M.H., Jolicoeur P. The AIDS disease of CD4C/HIV transgenic mice shows impaired germinal centers and autoantibodies and develops in the absence of IFN-γ and IL-6. Immunity. 15:2001;173-185.
49. Rajewsky K. Clonal selection and learning in the antibody system. Nature. 381:1996;751-758.
50. Reif K., Ekland E.H., Ohl L., Nakano H., Lipp M., Forster R., Cyster J.G. Balanced responsiveness to chemoattractants from adjacent zones determines B-cell position. Nature. 416:2002;94-99.
51. Rennert P.D., James D., Mackay F., Browning J.L., Hochman P.S. Lymph node genesis is induced by signaling through the lymphotoxin β receptor. Immunity. 9:1998;71-79.
52. Rickert R.C., Roes J., Rajewsky K. B lymphocyte-specific, Cre-mediated mutagenesis in mice. Nucleic Acids Res. 25:1997;1317-1318.
53. Ruuls S.R., Hoek R.M., Ngo V.N., McNeil T., Lucian L.A., Janatpour M.J., Korner H., Scheerens H., Hessel E.M., Cyster J.G.et al. Membrane-bound TNF supports secondary lymphoid organ structure but is subservient to secreted TNF in driving autoimmune inflammation. Immunity. 15:2001;533-543.
54. Schiemann B., Gommerman J.L., Vora K., Cachero T.G., Shulga-Morskaya S., Dobles M., Frew E., Scott M.L. An essential role for BAFF in the normal development of B cells through a BCMA-independent pathway. Science. 293:2001;2111-2114.
55. Shakhov A.N., Lyakhov I.G., Tumanov A.V., Rubtsov A.V., Drutskaya L.N., Marino M.W., Nedospasov S.A. Gene profiling approach in the analysis of lymphotoxin and TNF deficiencies. J. Leukoc. Biol. 68:2000;151-157.
56. Smith B.A., Gartner S., Liu Y., Perelson A.S., Stilianakis N.I., Keele B.F., Kerkering T.M., Ferreira-Gonzalez A., Szakal A.K., Tew J.G., Burton G.F. Persistence of infectious HIV on follicular dendritic cells. J. Immunol. 166:2001;690-696.
57. Takahama Y., Ohishi K., Tokoro Y., Sugawara T., Yoshimura Y., Okabe M., Kinoshita T., Takeda J. Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-a gene. Eur. J. Immunol. 28:1998;2159-2166.
58. Takemura S., Braun A., Crowson C., Kurtin P.J., Cofield R.H., O'Fallon W.M., Goronzy J.J., Weyand C.M. Lymphoid neogenesis in rheumatoid synovitis. J. Immunol. 167:2001;1072-1080.
59. Tew J.G., Wu J., Qin D., Helm S., Burton G.F., Szakal A.K. Follicular dendritic cells and presentation of antigen and costimulatory signals to B cells. Immunol. Rev. 156:1997;39-52.
60. van den Berg T.K., Breve J.J., Damoiseaux J.G., Dopp E.A., Kelm S., Crocker P.R., Dijkstra C.D., Kraal G. Sialoadhesin on macrophages. its identification as a lymphocyte adhesion molecule J. Exp. Med. 176:1992;647-655.
61. Van Vliet E., Melis M., van Ewijk W. Marginal zone macrophages in the mouse spleen identified by a monoclonal antibody. Anatomical correlation with a B cell subpopulation. J. Histochem. Cytochem. 33:1985;40-44.
62. Wang Y., Wang J., Sun Y., Wu Q., Fu Y.X. Complementary effects of TNF and lymphotoxin on the formation of germinal center and follicular dendritic cells. J. Immunol. 166:2001;330-337.
63. Ware C.F., Crowe P.D., Grayson M.H., Androlewicz M.J., Browning J.L. Expression of surface lymphotoxin and tumor necrosis factor on activated T, B, and natural killer cells. J. Immunol. 149:1992;3881-3888.
64. Worm M., Geha R.S. CD40 ligation induces lymphotoxin alpha gene expression in human B cells. Int. Immunol. 6:1994;1883-1890.
65. Wu Q., Salomon B., Chen M., Wang Y., Hoffman L.M., Bluestone J.A., Fu Y.X. Reversal of spontaneous autoimmune insulitis in nonobese diabetic mice by soluble lymphotoxin receptor. J. Exp. Med. 193:2001;1327-1332.
66. Wu X., Jiang N., Fang Y.F., Xu C., Mao D., Singh J., Fu Y.X., Molina H. Impaired affinity maturation in Cr2-/- mice is rescued by adjuvants without improvement in germinal center development. J. Immunol. 165:2000;3119-3127.
67. Yoshida K., van den Berg T.K., Dijkstra C.D. Two functionally different follicular dendritic cells in secondary lymphoid follicles of mouse spleen, as revealed by CR1/2 and FcR gamma II-mediated immune-complex trapping. Immunology. 80:1993;34-39.