Characterization of the glyceraldehyde-3-phosphate gene and the use of its promoter for heterologous expression in Cryptococcus neoformans, a human pathogen

Gene

Volumn 232, Issue 2, 1999, Pages 155-163

  Varma, A ^a   Kwon Chung, K J ^a  

^a Sect Clin and Exp Neuropsychol   (United States)

Author keywords

Gene expression; GPD; Hygromycin; Plasmid; Transformation

Indexed keywords

GLYCERALDEHYDE 3 PHOSPHATE; HYGROMYCIN;

ARTICLE; CRYPTOCOCCUS NEOFORMANS; GENE EXPRESSION; GENE ISOLATION; GENE STRUCTURE; GENETIC TRANSFORMATION; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; SEQUENCE ANALYSIS;

AMINO ACID SEQUENCE; BASE SEQUENCE; CLONING, MOLECULAR; CRYPTOCOCCUS NEOFORMANS; GENE EXPRESSION REGULATION; GENES, FUNGAL; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; HUMANS; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS (GENETICS); SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, DNA;

EID: 0033620625     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(99)00132-8     Document Type: Article

References (20)

1. Chang Y.C., Kwon-Chung K.J. Complementation of a capsule-deficient mutant of Cryptococcus neoformans restores its virulence. Mol. Cell. Biol. 14:1994;4912-4919.
2. Chang Y.C., Penoyer L., Kwon-Chung K.J. The second capsule gene of Cryptococcus neoformans, CAP64, is essential for virulence. Infect. Immun. 64:1996;1977-1983.
3. Cox G.M., Toffaletti D.L., Perfect J.R. Dominant selection system for use in Cryptococcus neoformans. J. Med. Vet. Mycol. 34:1996;385-391.
4. Edens L.E., Bom J., Ledeboer A.M., Maat J., Toonen M.Y., Visser C., Verrips C.T. Synthesis and processing of the plant protein thaumatin in yeast. Cell. 37:1984;629-633.
5. Gantla S., Bakker C.T., Deocharan B., Thummala N.R., Zweiner J., Sinaasappel M., Roy Chowdhury J., Bosma P.J., Roy Chowdary N. Splice site mutations: a novel mechanism of Crigler-Najjar syndrome type 1. Am. J. Hum. Genet. 62:1998;585-592.
6. Guo Z., Sherman F. 3′-end-forming signals of yeast mRNA. Mol. Cell. Biol. 15:1995;5983-5990.
7. Gurr S.J., Unkles S.E., Kinghorn J.R. Kinghorn J.R. Gene structure in eukaryotic microbes. 1987;93-139 IRL Press, Oxford.
8. Harmsen M.C., Schuren F.H.J., Moukha S.M., van Zuilen C.M., Punt P.J., Wessels J.G.H. Sequence analysis of the glyceraldehyde-3-phosphate dehydrogenase genes from the basidiomycetes Schizophyllum commune, Phanerochaete chrysosporium and Agaricus bisporus. Curr. Genet. 22:1992;447-454.
9. Holland M.J., Holland J.P. Isolation and identification of yeast messenger ribonucleic acids coding for enolase glyceraldehyde-3-phosphate dehydrogenase and phosphoglycerate kinase. Biochemistry. 17:1978;4900-4907.
10. Kwon-Chung K.J., Edman J.C., Wickes B.L. Genetic association of mating types and virulence in Cryptococcus neoformans. Infect. Immun. 60:1992;602-605.
11. Mooibroek H., Kuipers A.G.J., Sietsma J.H., Punt P.J., Wessels J.G.H. Introduction of hygromycin B resistance into Schizophyllum commune: preferential methylation of donor DNA. Mol. Gen. Genet. 222:1990;41-48.
12. Punt P.J., Dingemanse M.A., Kuyvenhoven A., Soede R.D.M., Pouwels P.M., Vanden Hondel C.A.M.J.J. Functional elements in the promoter region of the Aspergillus nidulans gpdA gene encoding glyceraldehyde-3-phosphate dehydrogenase. Gene. 93:1990;101-109.
13. Schuren F.H.J., Harmsen M.C., Wessels J.G. A homologous gene-reporter system for the basidiomycete Schizophyllum commune based on internally deleted homologus genes. Mol. Gen. Genet. 238:1993;91-96.
14. Southern E. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:1975;503-518.
15. Varma A., Kwon-Chung K.J. Molecular and genetic analysis of URA5 transformants of Cryptococcus neoformans. Infect. Immun. 60:1992;1101-1108.
16. Varma A., Kwon-Chung K.J. Generation of a minichromosome in Cryptococcus neoformans. Curr. Genet. 26:1994;51-54.
17. Varma A., Kwon-Chung K.J. Construction of stable episomes in Cryptococcus neoformans. Curr. Genet. 34:1998;60-66.
18. von Arnim A.G. Genetic and developmental control of nuclear accumulation of COP1, a repressor of photomorphogenesis in Arabidopsis. Plant Physiol. 114:1997;779-788.
19. Wickes B.L., Edman J.C. Isolation of the Cryptococcus neoformans GAL7 gene and its use as an inducible promoter. Mol. Microbiol. 16:1995;1099-1109.
20. Williamson P.R. Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccase. J. Bacteriol. 176:1994;656-664.