Different synthetic strategies of oseltamivir phosphate: A potent influenza neuraminidase inhibitor

Current Medicinal Chemistry

Volumn 15, Issue 30, 2008, Pages 3145-3159

  Gong, Jianzhi ^a   Xu, Wenfang ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Neuraminidase inhibitor; Oseltamivir phosphate (Tamiflu); Synthetic strategies

Indexed keywords

1 (TRIMETHYLSILOXY) 1,3 BUTADIENE; 1,3 BUTADIENE DERIVATIVE; 1,6 DIMETHOXY PHENOL; 4 ACETAMIDO 5 AMINO 3 (1 ETHYLPROPOXY) 1 CYCLOHEXENE 1 CARBOXYLIC ACID; ALLYLAMINE; AMANTADINE; AZIRIDINE DERIVATIVE; CYCLOHEXANECARBOXYLIC ACID DERIVATIVE; EPOXIDE; MESO AZIRIDINE; N TRITYL AZIRIDINE AZIDE; OSELTAMIVIR; PHENOL DERIVATIVE; PYRIDINE; QUINIC ACID; RIMANTADINE; SERINE; SHIKIMIC ACID; SIALIDASE; SIALIDASE INHIBITOR; TERT BUTYLAMINE DIALLYLAMINE; UNCLASSIFIED DRUG; XYLOSE; ZANAMIVIR; ANTIVIRUS AGENT; ENZYME INHIBITOR;

ASYMMETRIC SYNTHESIS; AVIAN INFLUENZA; DIELS ALDER REACTION; DRUG BIOAVAILABILITY; DRUG DESIGN; DRUG EFFICACY; DRUG HALF LIFE; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVE SITE; ENZYME INHIBITION; HUMAN; IC 50; INFLUENZA; INFLUENZA VIRUS A H5N1; REVIEW; UNSPECIFIED SIDE EFFECT; CHEMISTRY; CONFORMATION; DRUG ANTAGONISM; ENZYMOLOGY; METABOLISM; STEREOISOMERISM; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTIVIRAL AGENTS; ENZYME INHIBITORS; HUMANS; INFLUENZA, HUMAN; MOLECULAR CONFORMATION; NEURAMINIDASE; OSELTAMIVIR; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 61549140440     PISSN: 09298673     EISSN: None     Source Type: Journal    
DOI: 10.2174/092986708786848497     Document Type: Review

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