The synthetic development of the anti-influenza neuraminidase inhibitor oseltamivir phosphate (Tamiflu®): A challenge for synthesis & process research

Chimia

Volumn 58, Issue 9, 2004, Pages 621-629

  Abrecht, Stefan ^a   Harrington, Peter ^b   Iding, Hans ^a   Karpf, Martin ^a   Trussardi, René ^a   Wirz, Beat ^a   Zutter, Ulrich ^a  

^a F HOFFMANN LA ROCHE LTD   (Switzerland)

^b Roche Colorado   (United States)

Author keywords

Biotechnology; Influenza neuraminidase inhibitor; Process research; Synthesis

Indexed keywords

AZIDE; EPOXIDE; INFLUENZA VACCINE; OSELTAMIVIR; SHIKIMIC ACID;

DIELS ALDER REACTION; DRUG POTENCY; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; INFLUENZA; NONHUMAN; REVIEW;

EID: 6444232887     PISSN: 00094293     EISSN: None     Source Type: Journal    
DOI: 10.2533/000942904777677605     Document Type: Review

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