메뉴 건너뛰기




Volumn 29, Issue 2, 2009, Pages 605-615

Chronic lymphocytic leukaemia

Author keywords

B cell receptor; Chronic lymphocytic leukaemia; Prognostic factors; Review

Indexed keywords

B LYMPHOCYTE RECEPTOR; CELL MARKER; DNA; MOLECULAR MARKER; PROTEIN KINASE ZAP 70; SURROGATE IMMUNOGLOBULIN LIGHT CHAIN;

EID: 61549116212     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (16)

References (126)
  • 1
    • 51649104731 scopus 로고    scopus 로고
    • Disease burden of chronic lymphocytic leukaemia within the European Union
    • Jun 30
    • Watson L, Wyld P and Catovsky D: Disease burden of chronic lymphocytic leukaemia within the European Union. Eur J Haematology, Jun 30, 2008.
    • (2008) Eur J Haematology
    • Watson, L.1    Wyld, P.2    Catovsky, D.3
  • 2
    • 3042516892 scopus 로고    scopus 로고
    • Redaelli A, Laskin BL, Stephens JM, Botteman MF and Phases CL: The clinical and epidemiological burden of chronic lymphocytic leukaemia. Eur J Cancer Care 13: 279-287, 2004.
    • Redaelli A, Laskin BL, Stephens JM, Botteman MF and Phases CL: The clinical and epidemiological burden of chronic lymphocytic leukaemia. Eur J Cancer Care 13: 279-287, 2004.
  • 3
    • 12444270921 scopus 로고    scopus 로고
    • Ries LAG, Eisner MP, Kosary CL, Hankey BF, Miller BA, Clegg L, Mariotto A, Fay MP, Feuer EJ and Edwards BK eds, National Cancer Institute, Bethesda, MD, Available at
    • Ries LAG, Eisner MP, Kosary CL, Hankey BF, Miller BA, Clegg L, Mariotto A, Fay MP, Feuer EJ and Edwards BK (eds.): Surveillance, Epidemiology and End Results (SEER) Cancer Statistics Review 1975-2000. National Cancer Institute, Bethesda, MD, 2003. Available at: http://seer.cancer.gov/csr/1975_2000.
    • (2003) Surveillance, Epidemiology and End Results (SEER) Cancer Statistics Review 1975-2000
  • 4
    • 0032707533 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia
    • Kalil N and Cheson BD: Chronic lymphocytic leukaemia. The Oncologist 4: 352-369, 1999.
    • (1999) The Oncologist , vol.4 , pp. 352-369
    • Kalil, N.1    Cheson, B.D.2
  • 6
    • 0036615776 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia. Current Treat Options
    • Andritsos L and Khoury H: Chronic lymphocytic leukaemia. Current Treat Options Oncology 3: 225-231, 2002.
    • (2002) Oncology , vol.3 , pp. 225-231
    • Andritsos, L.1    Khoury, H.2
  • 7
    • 0036269721 scopus 로고    scopus 로고
    • Genetic susceptibility to chronic lymphocytic leukaemia
    • Houlston RS, Catovsky D and Yuille MR: Genetic susceptibility to chronic lymphocytic leukaemia. Leukaemia 16: 1008-1014, 2002.
    • (2002) Leukaemia , vol.16 , pp. 1008-1014
    • Houlston, R.S.1    Catovsky, D.2    Yuille, M.R.3
  • 9
    • 0020961988 scopus 로고
    • Lymphocytic leukaemia and exposure to benzene and other solvents in the rubber industry
    • Arp EW Jr, Wolf PH and Checkoway H: Lymphocytic leukaemia and exposure to benzene and other solvents in the rubber industry. J Occup Med 25: 598-602, 1983.
    • (1983) J Occup Med , vol.25 , pp. 598-602
    • Arp Jr, E.W.1    Wolf, P.H.2    Checkoway, H.3
  • 12
    • 0034160344 scopus 로고    scopus 로고
    • Morphological and immunophenotypic features of chronic lymphocytic leukaemia
    • Matutes E and Polliack A: Morphological and immunophenotypic features of chronic lymphocytic leukaemia. Rev Clin Exp Hematol 4: 22-47, 2000.
    • (2000) Rev Clin Exp Hematol , vol.4 , pp. 22-47
    • Matutes, E.1    Polliack, A.2
  • 16
    • 0017751562 scopus 로고
    • Vauqier, Beral HM, Natali JC, Raphael M, Nizet B and Follezou JY: A clinical staging system for chronic lymphocytic leukaemia: prognostic significance
    • Binet J, Lepoprier M, Dighiero G, Charron D, D'Athis P, Vauqier, Beral HM, Natali JC, Raphael M, Nizet B and Follezou JY: A clinical staging system for chronic lymphocytic leukaemia: prognostic significance. Cancer 40: 855-864, 1977.
    • (1977) Cancer , vol.40 , pp. 855-864
    • Binet, J.1    Lepoprier, M.2    Dighiero, G.3    Charron, D.4    D'Athis, P.5
  • 20
    • 0014007964 scopus 로고
    • The pathogenesis of chronic lymphocytic leukaemia
    • Gallon D: The pathogenesis of chronic lymphocytic leukaemia. Can Med Ass J 94: 1005-1010, 1966.
    • (1966) Can Med Ass J , vol.94 , pp. 1005-1010
    • Gallon, D.1
  • 22
    • 0023088947 scopus 로고
    • The relationship between chronic lymphocytic leukaemia and prolymphocytic leukaemia. IV. Analysis of survival and prognostic features
    • Melo J, Catovsky D, Gregory W and Gallon D: The relationship between chronic lymphocytic leukaemia and prolymphocytic leukaemia. IV. Analysis of survival and prognostic features. Br J Haematol 65: 23-29, 1978.
    • (1978) Br J Haematol , vol.65 , pp. 23-29
    • Melo, J.1    Catovsky, D.2    Gregory, W.3    Gallon, D.4
  • 23
    • 0019401836 scopus 로고
    • Prognostic significance of bone marrow patterns in chronic lymphocytic leukaemia
    • Rozman C, Hernandez-Nieto L, Montserrat E and Brugues R: Prognostic significance of bone marrow patterns in chronic lymphocytic leukaemia. Br J Haematol 47: 529-537, 1981.
    • (1981) Br J Haematol , vol.47 , pp. 529-537
    • Rozman, C.1    Hernandez-Nieto, L.2    Montserrat, E.3    Brugues, R.4
  • 24
    • 0029829395 scopus 로고    scopus 로고
    • Serum β2 microglobulin and serum thymidine kinase are independent predictors of progression-free survival in chronic lymphocytic leukaemia and immunocytoma
    • Hallek M, Wanders L, Ostwald M, Busch R, Senekowitsch R, Stern S, Schick HD, Kuhn-Hallek I and Emmerich B: Serum β2 microglobulin and serum thymidine kinase are independent predictors of progression-free survival in chronic lymphocytic leukaemia and immunocytoma. Leuk Lymphoma 22: 439-447, 1996.
    • (1996) Leuk Lymphoma , vol.22 , pp. 439-447
    • Hallek, M.1    Wanders, L.2    Ostwald, M.3    Busch, R.4    Senekowitsch, R.5    Stern, S.6    Schick, H.D.7    Kuhn-Hallek, I.8    Emmerich, B.9
  • 30
    • 0031890032 scopus 로고    scopus 로고
    • Molecular biology of chronic lymphocytic leukaemia
    • Reed JC: Molecular biology of chronic lymphocytic leukaemia. Semin Oncol 25: 11-18, 1998.
    • (1998) Semin Oncol , vol.25 , pp. 11-18
    • Reed, J.C.1
  • 31
    • 0026533307 scopus 로고
    • Detection of trisomy 12 in chronic lymphocytic leukaemia by fluorescence in situ hybridization to interphase cell: A simple and sensitive method
    • Anastasi J, Le Beau MM, Vardiman JW, Fernald AA, Larson RA and Rowley JD: Detection of trisomy 12 in chronic lymphocytic leukaemia by fluorescence in situ hybridization to interphase cell: a simple and sensitive method. Blood 79: 1796-1801, 1992.
    • (1992) Blood , vol.79 , pp. 1796-1801
    • Anastasi, J.1    Le Beau, M.M.2    Vardiman, J.W.3    Fernald, A.A.4    Larson, R.A.5    Rowley, J.D.6
  • 32
    • 0031976628 scopus 로고    scopus 로고
    • Molecular cytogenetic analysis of B-cell chronic lymphocytic leukaemia
    • Stilgenbauer S, Dönner K, Bentz M, Lichter P and Dönner H: Molecular cytogenetic analysis of B-cell chronic lymphocytic leukaemia. Ann Hematol 76: 101-110, 1998.
    • (1998) Ann Hematol , vol.76 , pp. 101-110
    • Stilgenbauer, S.1    Dönner, K.2    Bentz, M.3    Lichter, P.4    Dönner, H.5
  • 33
    • 0034727833 scopus 로고    scopus 로고
    • Dohner H, Stilgenbauer S, Benner A, Leupolt E, Krober A, Bullinger, Dohner K, Bentz M and Lichter P: Genomic aberrations and survival in chronic lymphocytic leukaemia. N Engl J Med 343: 1910-1916, 2000.
    • Dohner H, Stilgenbauer S, Benner A, Leupolt E, Krober A, Bullinger, Dohner K, Bentz M and Lichter P: Genomic aberrations and survival in chronic lymphocytic leukaemia. N Engl J Med 343: 1910-1916, 2000.
  • 38
    • 34447530283 scopus 로고    scopus 로고
    • Catovsky D, Richards S, Matutes E, Oscier D, Dyer MJS, Bezares RF, Pettitt AR, Hamblin T, Milligan DW, Child JA, Hamilton MS, Dearden CE, Smith AG, Bosanquet AG, Davis Z, Brito-Babapulle V, Else M, Wade R and Hillmen P, on behalf of the UK National Cancer Research Institute (NCRI) Hematological Oncology Clinical Studies Group and NCRI Chronic Lymphocytic Leukaemia Working Group: Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 trial): a randomised controlled trial. The Lancet 370: 230-239, 2007.
    • Catovsky D, Richards S, Matutes E, Oscier D, Dyer MJS, Bezares RF, Pettitt AR, Hamblin T, Milligan DW, Child JA, Hamilton MS, Dearden CE, Smith AG, Bosanquet AG, Davis Z, Brito-Babapulle V, Else M, Wade R and Hillmen P, on behalf of the UK National Cancer Research Institute (NCRI) Hematological Oncology Clinical Studies Group and NCRI Chronic Lymphocytic Leukaemia Working Group: Assessment of fludarabine plus cyclophosphamide for patients with chronic lymphocytic leukaemia (the LRF CLL4 trial): a randomised controlled trial. The Lancet 370: 230-239, 2007.
  • 39
    • 35348996680 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia: Current and emerging treatment approaches
    • Kay NE, Rai KR and O'Brien S: Chronic lymphocytic leukaemia: current and emerging treatment approaches. Clin Adv Hematol Oncol 11(Suppl 22): 1-12, 2006.
    • (2006) Clin Adv Hematol Oncol , vol.11 , Issue.SUPPL. 22 , pp. 1-12
    • Kay, N.E.1    Rai, K.R.2    O'Brien, S.3
  • 40
    • 0036942874 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia: One disease or two?
    • Hamblin T: Chronic lymphocytic leukaemia: one disease or two? Ann Hematol 81: 299-303, 2002.
    • (2002) Ann Hematol , vol.81 , pp. 299-303
    • Hamblin, T.1
  • 41
    • 0028355650 scopus 로고
    • The pathogenesis of chronic lymphocytic leukaemia: Analysis of the antibody repertoire
    • Schroeder HW Jr and Dighiero G: The pathogenesis of chronic lymphocytic leukaemia: analysis of the antibody repertoire. Immunol Today 15: 288-294, 1994.
    • (1994) Immunol Today , vol.15 , pp. 288-294
    • Schroeder Jr, H.W.1    Dighiero, G.2
  • 43
    • 0030905707 scopus 로고    scopus 로고
    • Differential rates of somatic hypermutation in VH genes among subsets of chronic lymphocytic leukaemia defined by chromosomal abnormalities
    • Oscier DG, Thompsett A, Zhu D and Stevenson FK: Differential rates of somatic hypermutation in VH genes among subsets of chronic lymphocytic leukaemia defined by chromosomal abnormalities. Blood 89: 4153-4160, 1997.
    • (1997) Blood , vol.89 , pp. 4153-4160
    • Oscier, D.G.1    Thompsett, A.2    Zhu, D.3    Stevenson, F.K.4
  • 44
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukaemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG and Stevenson FK: Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukaemia. Blood 94: 1848-1854, 1999.
    • (1999) Blood , vol.94 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 48
    • 0037103212 scopus 로고    scopus 로고
    • V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukaemia
    • Krober A, Seiler T, Benner A, Bullinger L, Bruckle E, Lichter P, Dohner H and Stilgenbauer S: V(H) mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukaemia. Blood 100: 1410-1416, 2002.
    • (2002) Blood , vol.100 , pp. 1410-1416
    • Krober, A.1    Seiler, T.2    Benner, A.3    Bullinger, L.4    Bruckle, E.5    Lichter, P.6    Dohner, H.7    Stilgenbauer, S.8
  • 49
    • 0037103272 scopus 로고    scopus 로고
    • Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukaemia
    • Lin K, Sherrington PD, Dennis M, Matrai Z, Cawley JC and Pettitt AR: Relationship between p53 dysfunction, CD38 expression, and IgV(H) mutation in chronic lymphocytic leukaemia. Blood 100: 1404-1409, 2002.
    • (2002) Blood , vol.100 , pp. 1404-1409
    • Lin, K.1    Sherrington, P.D.2    Dennis, M.3    Matrai, Z.4    Cawley, J.C.5    Pettitt, A.R.6
  • 50
    • 0141992960 scopus 로고    scopus 로고
    • Divergence from the germline sequence in unmutated chronic lymphocytic leukaemia is due to somatic mutation rather than polymorphisms
    • Davis ZA, Orchard JA, Corcoran MM and Oscier DG: Divergence from the germline sequence in unmutated chronic lymphocytic leukaemia is due to somatic mutation rather than polymorphisms. Blood 102: 3075, 2003.
    • (2003) Blood , vol.102 , pp. 3075
    • Davis, Z.A.1    Orchard, J.A.2    Corcoran, M.M.3    Oscier, D.G.4
  • 54
    • 13944261903 scopus 로고    scopus 로고
    • Tout ce que vous avez toujours voulu savoir sur la protéine ZAP-70.
    • Hivroz C: Tout ce que vous avez toujours voulu savoir sur la protéine ZAP-70. Médecine/Sciences 21: 150-155, 2005.
    • (2005) Médecine/Sciences , vol.21 , pp. 150-155
    • Hivroz, C.1
  • 55
    • 20844449062 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia and normal B-cells. ZAP-70 is expressed by a subset of normal human B-lymphocytes displaying an activated phenotype
    • Nolz JC, Tschumper RC, Pittner BT, Darce JR, Kay NE and Jelinek DF: Chronic lymphocytic leukaemia and normal B-cells. ZAP-70 is expressed by a subset of normal human B-lymphocytes displaying an activated phenotype. Leukaemia 19: 1018-1024, 2005.
    • (2005) Leukaemia , vol.19 , pp. 1018-1024
    • Nolz, J.C.1    Tschumper, R.C.2    Pittner, B.T.3    Darce, J.R.4    Kay, N.E.5    Jelinek, D.F.6
  • 58
    • 0032010114 scopus 로고    scopus 로고
    • Molecular dissection of B-cell antigen receptor signaling
    • Kurosaki T: Molecular dissection of B-cell antigen receptor signaling. Int J Mol Med 1: 515-527, 1998.
    • (1998) Int J Mol Med , vol.1 , pp. 515-527
    • Kurosaki, T.1
  • 59
    • 0036884819 scopus 로고    scopus 로고
    • Regulation of B-cell fate by antigen-receptor signals
    • Niiro H and Clark EA: Regulation of B-cell fate by antigen-receptor signals. Nat Rev Immunol 2: 945-956, 2002.
    • (2002) Nat Rev Immunol , vol.2 , pp. 945-956
    • Niiro, H.1    Clark, E.A.2
  • 60
    • 0031897046 scopus 로고    scopus 로고
    • Positive versus negative signaling by lymphocyte antigen receptors
    • Healy JI and Goodnow CC: Positive versus negative signaling by lymphocyte antigen receptors. Annu Rev Immunol 16: 645-670, 1998.
    • (1998) Annu Rev Immunol , vol.16 , pp. 645-670
    • Healy, J.I.1    Goodnow, C.C.2
  • 62
    • 0033672473 scopus 로고    scopus 로고
    • Lymphocytes with a complex: Adapter proeins in antigen receptor signaling
    • Tomlinsom MG, Lin J and Weiss A: Lymphocytes with a complex: adapter proeins in antigen receptor signaling. Immunol Today 21: 584-591, 2002.
    • (2002) Immunol Today , vol.21 , pp. 584-591
    • Tomlinsom, M.G.1    Lin, J.2    Weiss, A.3
  • 63
    • 85117737773 scopus 로고    scopus 로고
    • Steinberg M, Adjali O, Swainson L, Merida P, Di BV, Pelletier L, Taylor N and Noraz N: T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk. Blood 104: 760-767, 2004.
    • Steinberg M, Adjali O, Swainson L, Merida P, Di BV, Pelletier L, Taylor N and Noraz N: T-cell receptor-induced phosphorylation of the zeta chain is efficiently promoted by ZAP-70 but not Syk. Blood 104: 760-767, 2004.
  • 70
    • 34547907101 scopus 로고    scopus 로고
    • Prognostic markers in chronic lymphocytic leukaemia
    • Hamblin TJ: Prognostic markers in chronic lymphocytic leukaemia. Best Pract Res Clin Haematol 20(3): 455-468, 2007.
    • (2007) Best Pract Res Clin Haematol , vol.20 , Issue.3 , pp. 455-468
    • Hamblin, T.J.1
  • 71
    • 33748515699 scopus 로고    scopus 로고
    • ZAP-70 in CLL: Towards standardization of a biomarker for patient management: history of clinical cytometry special issue. Cytometry. Part B
    • Marti G, Orfao A and Goolsby C: ZAP-70 in CLL: towards standardization of a biomarker for patient management: history of clinical cytometry special issue. Cytometry. Part B, Clinical Cytometry 70B: 197-200, 2006.
    • (2006) Clinical Cytometry , vol.70 B , pp. 197-200
    • Marti, G.1    Orfao, A.2    Goolsby, C.3
  • 72
    • 33748484481 scopus 로고    scopus 로고
    • ZAP-70 by flow ytometry: A comparison of different antibodies, anticoagulants and methods of analysis. Cytometry. Part B
    • Best OG, Ibbotson RE, Parker AE, Davis ZA, Orchard JA and Oscier DG: ZAP-70 by flow ytometry: a comparison of different antibodies, anticoagulants and methods of analysis. Cytometry. Part B, Clinical Cytometry 70B: 235-241, 2006.
    • (2006) Clinical Cytometry , vol.70 B , pp. 235-241
    • Best, O.G.1    Ibbotson, R.E.2    Parker, A.E.3    Davis, Z.A.4    Orchard, J.A.5    Oscier, D.G.6
  • 75
    • 23744480792 scopus 로고    scopus 로고
    • Loss of ZAP-70 and low molecular weight phosphotyrosine phosphatase occurs after therapy in a patient with B-chronic lymphocytic leukaemia
    • Chen Z, Aston E and Yu M: Loss of ZAP-70 and low molecular weight phosphotyrosine phosphatase occurs after therapy in a patient with B-chronic lymphocytic leukaemia. Leukaemia 19: 1503-1505, 2005.
    • (2005) Leukaemia , vol.19 , pp. 1503-1505
    • Chen, Z.1    Aston, E.2    Yu, M.3
  • 77
    • 33748508638 scopus 로고    scopus 로고
    • Comparison of bone marrow and peripheral blood ZAP-70 status examined by flow cytometry immunophenotyping in patients with chronic lymphocytic leukaemia. Cytometry. Part B
    • Sheridan R, Mounajjed T, Ehrmann DE, Hurtubise PE and Schrager JA: Comparison of bone marrow and peripheral blood ZAP-70 status examined by flow cytometry immunophenotyping in patients with chronic lymphocytic leukaemia. Cytometry. Part B, Clinical Cytometry 70B: 320-321, 2006.
    • (2006) Clinical Cytometry , vol.70 B , pp. 320-321
    • Sheridan, R.1    Mounajjed, T.2    Ehrmann, D.E.3    Hurtubise, P.E.4    Schrager, J.A.5
  • 78
    • 34147157129 scopus 로고    scopus 로고
    • B-CLL cells from lymph nodes express higher ZAP-70 levels than B-CLL cells from peripheral blood
    • Boelens J, Phillipe J and Offner F: B-CLL cells from lymph nodes express higher ZAP-70 levels than B-CLL cells from peripheral blood. Leuk Res 31(5): 719-720, 2007.
    • (2007) Leuk Res , vol.31 , Issue.5 , pp. 719-720
    • Boelens, J.1    Phillipe, J.2    Offner, F.3
  • 81
    • 0036464608 scopus 로고    scopus 로고
    • CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukaemia, but CD38 expression may vary during the course of the disease
    • Hamblin TJ, Orchard JA, Ibbotson RE, Davis Z, Thomas PW, Stevenson FK and Oscier DG: CD38 expression and immunoglobulin variable region mutations are independent prognostic variables in chronic lymphocytic leukaemia, but CD38 expression may vary during the course of the disease. Blood 99: 1023-1029, 2002.
    • (2002) Blood , vol.99 , pp. 1023-1029
    • Hamblin, T.J.1    Orchard, J.A.2    Ibbotson, R.E.3    Davis, Z.4    Thomas, P.W.5    Stevenson, F.K.6    Oscier, D.G.7
  • 82
    • 0037441762 scopus 로고    scopus 로고
    • The pattern of CD38 expression defines a distinct subset of chronic lymphocytic leukaemia (CLL) patients at risk of disease progression
    • Ghia P, Guida G, Stella S, Gottardi D, Geuna M, Strola G, Scielzo C and Caligaris-Cappio F: The pattern of CD38 expression defines a distinct subset of chronic lymphocytic leukaemia (CLL) patients at risk of disease progression. Blood 101: 1262-1269, 2003.
    • (2003) Blood , vol.101 , pp. 1262-1269
    • Ghia, P.1    Guida, G.2    Stella, S.3    Gottardi, D.4    Geuna, M.5    Strola, G.6    Scielzo, C.7    Caligaris-Cappio, F.8
  • 84
    • 0036460675 scopus 로고    scopus 로고
    • Lipoprotein lipase: Structure, function, regulation, and role in disease
    • Mead JR, Irvine SA and Ramji DP: Lipoprotein lipase: structure, function, regulation, and role in disease. J Mol Med 80: 753-769, 2002.
    • (2002) J Mol Med , vol.80 , pp. 753-769
    • Mead, J.R.1    Irvine, S.A.2    Ramji, D.P.3
  • 85
    • 0036775676 scopus 로고    scopus 로고
    • Lipoprotein lipase: The regulation of tissue-specific expression and its role in lipid and energy metabolism
    • Preiss-Landl K, Zimmermann R, Hammerle G and Zechner R: Lipoprotein lipase: the regulation of tissue-specific expression and its role in lipid and energy metabolism. Curr Opin Lipidol 13: 471-481, 2002.
    • (2002) Curr Opin Lipidol , vol.13 , pp. 471-481
    • Preiss-Landl, K.1    Zimmermann, R.2    Hammerle, G.3    Zechner, R.4
  • 87
    • 0036481264 scopus 로고    scopus 로고
    • Lipid rafts and B-cell activation
    • Pierce SK: Lipid rafts and B-cell activation. Nat Rev Immunol 2:96-105, 2002.
    • (2002) Nat Rev Immunol , vol.2 , pp. 96-105
    • Pierce, S.K.1
  • 88
    • 0033527442 scopus 로고    scopus 로고
    • Isolation of two novel metalloproteinase-disintegrin (ADAM) cDNAs that show testis-specific gene expression
    • Cerretti DP, DuBose RF, Black RA and Nelson N: Isolation of two novel metalloproteinase-disintegrin (ADAM) cDNAs that show testis-specific gene expression. Biochem Biophys Res Commun 263: 810-815, 1999.
    • (1999) Biochem Biophys Res Commun , vol.263 , pp. 810-815
    • Cerretti, D.P.1    DuBose, R.F.2    Black, R.A.3    Nelson, N.4
  • 89
    • 0033572363 scopus 로고    scopus 로고
    • Molecular cloning and mapping of a novel ADAM gene (ADAM29) to human chromosome 4
    • Xu R, Cai J, Xu T, Zhou W, Ying B, Deng K, Zhao S and Li C: Molecular cloning and mapping of a novel ADAM gene (ADAM29) to human chromosome 4. Genomics 62: 537-539, 1999.
    • (1999) Genomics , vol.62 , pp. 537-539
    • Xu, R.1    Cai, J.2    Xu, T.3    Zhou, W.4    Ying, B.5    Deng, K.6    Zhao, S.7    Li, C.8
  • 92
    • 33847378042 scopus 로고    scopus 로고
    • Lipoprotein lipase mRNA expression in whole blood is a prognostic marher in B cell chronic lymphocytic leukaemia
    • Van Bockstaele F, Pede V, Janssens A, Callewaert F, Offner F, Verhasselt B and Philippe J: Lipoprotein lipase mRNA expression in whole blood is a prognostic marher in B cell chronic lymphocytic leukaemia. Clin Chem 53(2): 204-212, 2007.
    • (2007) Clin Chem , vol.53 , Issue.2 , pp. 204-212
    • Van Bockstaele, F.1    Pede, V.2    Janssens, A.3    Callewaert, F.4    Offner, F.5    Verhasselt, B.6    Philippe, J.7
  • 93
    • 33746839511 scopus 로고    scopus 로고
    • 17p Deletion predicts for overall survival after fludarabine-based first line therapy in chronic lymhpocytic leukaemia: First analysis of genetics in the CLL4 trial of the GCLLSG
    • abstract 715
    • Stilgenbauer S, Krober A, Busch R, Eichhorst B, Kienle D, Winkler D and Hopfinger G: 17p Deletion predicts for overall survival after fludarabine-based first line therapy in chronic lymhpocytic leukaemia: first analysis of genetics in the CLL4 trial of the GCLLSG. Blood 106: 212a (abstract 715), 2005.
    • (2005) Blood , vol.106
    • Stilgenbauer, S.1    Krober, A.2    Busch, R.3    Eichhorst, B.4    Kienle, D.5    Winkler, D.6    Hopfinger, G.7
  • 94
    • 33644847307 scopus 로고    scopus 로고
    • Select high-risk features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukaemia: Justification for risk-adapted strategy
    • Byrd JC, Gribben JG, Peterson BL, Grever MR, Lozanski G, Lucas DM, Lampson B, Larson RA, Caligiuri MA and Heerema NA: Select high-risk features predict earlier progression following chemoimmunotherapy with fludarabine and rituximab in chronic lymphocytic leukaemia: justification for risk-adapted strategy. J Clin Oncol 24: 437-443, 2006.
    • (2006) J Clin Oncol , vol.24 , pp. 437-443
    • Byrd, J.C.1    Gribben, J.G.2    Peterson, B.L.3    Grever, M.R.4    Lozanski, G.5    Lucas, D.M.6    Lampson, B.7    Larson, R.A.8    Caligiuri, M.A.9    Heerema, N.A.10
  • 96
    • 0029788103 scopus 로고    scopus 로고
    • Differential intrinsic enzymatic activity of Syk and ZAP-70 protein-tyrosine kinases
    • Latour S, Chow LM and Veillette A: Differential intrinsic enzymatic activity of Syk and ZAP-70 protein-tyrosine kinases. J Biol Chem 271: 22782-22790, 1996.
    • (1996) J Biol Chem , vol.271 , pp. 22782-22790
    • Latour, S.1    Chow, L.M.2    Veillette, A.3
  • 97
    • 0037114744 scopus 로고    scopus 로고
    • Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymophocytic leukaemia
    • Chen L, Widhopf G, Huynh L, Rassenti L, Rai KR, Weiss A and Kipps TJ: Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymophocytic leukaemia. Blood 100: 4609-4614, 2002.
    • (2002) Blood , vol.100 , pp. 4609-4614
    • Chen, L.1    Widhopf, G.2    Huynh, L.3    Rassenti, L.4    Rai, K.R.5    Weiss, A.6    Kipps, T.J.7
  • 99
    • 33847412872 scopus 로고    scopus 로고
    • ZAP-70 enhances B-cell receptor signaling in spite of absent or inefficient tyrosine kinase activation in chronic lymphocytic leukaemia and lymphoma B-cells
    • Gobessi S, Laurenti L, Longo PG, Sica S, Leone G and Efremov DG: ZAP-70 enhances B-cell receptor signaling in spite of absent or inefficient tyrosine kinase activation in chronic lymphocytic leukaemia and lymphoma B-cells. Blood 109: 2032-2039, 2007.
    • (2007) Blood , vol.109 , pp. 2032-2039
    • Gobessi, S.1    Laurenti, L.2    Longo, P.G.3    Sica, S.4    Leone, G.5    Efremov, D.G.6
  • 100
    • 0032555744 scopus 로고    scopus 로고
    • Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the chrystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide
    • Futterer K, Wong J, Grucza RA, Chan AC and Waksman G: Structural basis for Syk tyrosine kinase ubiquity in signal transduction pathways revealed by the chrystal structure of its regulatory SH2 domains bound to a dually phosphorylated ITAM peptide. J Mol Biol 281: 523-537, 1998.
    • (1998) J Mol Biol , vol.281 , pp. 523-537
    • Futterer, K.1    Wong, J.2    Grucza, R.A.3    Chan, A.C.4    Waksman, G.5
  • 101
    • 27144551963 scopus 로고    scopus 로고
    • ZAP-70 is a novel conditional heat-shock protein 90 (Hsp90) client: Anhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukaemia
    • Castro JE, Prada CE, Loria O, Kamal A, Chen L, Burrows FJ and Kipps TJ: ZAP-70 is a novel conditional heat-shock protein 90 (Hsp90) client: anhibition of Hsp90 leads to ZAP-70 degradation, apoptosis, and impaired signaling in chronic lymphocytic leukaemia. Blood 106: 2506-2512, 2005.
    • (2005) Blood , vol.106 , pp. 2506-2512
    • Castro, J.E.1    Prada, C.E.2    Loria, O.3    Kamal, A.4    Chen, L.5    Burrows, F.J.6    Kipps, T.J.7
  • 102
    • 34547930555 scopus 로고    scopus 로고
    • The B-cell receptor and ZAP-70 in chronic lymphocytic leukaemia
    • Kipps TJ: The B-cell receptor and ZAP-70 in chronic lymphocytic leukaemia. Best Prac Res Clin Haematol 20(3): 415-424, 2007.
    • (2007) Best Prac Res Clin Haematol , vol.20 , Issue.3 , pp. 415-424
    • Kipps, T.J.1
  • 104
    • 34547855136 scopus 로고    scopus 로고
    • Cell proliferation and death: Forgotten features of chronic lymphocytic leukaemia
    • Chiorazzi N: Cell proliferation and death: forgotten features of chronic lymphocytic leukaemia. Best Prac Res Clin Haematol 20(3): 399-413, 2007.
    • (2007) Best Prac Res Clin Haematol , vol.20 , Issue.3 , pp. 399-413
    • Chiorazzi, N.1
  • 106
    • 39049186475 scopus 로고    scopus 로고
    • Evolving view of the in-vivo kinetics of chronic lymphocytic leukemia B cells
    • Chiorazzi N and Ferrarini M: Evolving view of the in-vivo kinetics of chronic lymphocytic leukemia B cells. Haematology Am Soc Haematol Educ Program 512: 273-278, 2006.
    • (2006) Haematology Am Soc Haematol Educ Program , vol.512 , pp. 273-278
    • Chiorazzi, N.1    Ferrarini, M.2
  • 108
    • 0033214567 scopus 로고    scopus 로고
    • Measurement of T-cell kinetics: Recent methodologic advances
    • Hellerstein MK: Measurement of T-cell kinetics: recent methodologic advances. Immunology Today 20(10): 438-441, 1999.
    • (1999) Immunology Today , vol.20 , Issue.10 , pp. 438-441
    • Hellerstein, M.K.1
  • 112
    • 0029836635 scopus 로고    scopus 로고
    • CD38 expression distinguishes two groups of B-cell chronic lymphocytic leukaemias with different responses to anti-IgM antibodies and propensity to apoptosis
    • Zupo S, Isnardi L, Megna M, Massara R, Malavasi F, Dono M, Cosulich E and Ferrarini M: CD38 expression distinguishes two groups of B-cell chronic lymphocytic leukaemias with different responses to anti-IgM antibodies and propensity to apoptosis. Blood 88(4): 1365-1374, 1996.
    • (1996) Blood , vol.88 , Issue.4 , pp. 1365-1374
    • Zupo, S.1    Isnardi, L.2    Megna, M.3    Massara, R.4    Malavasi, F.5    Dono, M.6    Cosulich, E.7    Ferrarini, M.8
  • 113
    • 0030048565 scopus 로고    scopus 로고
    • Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro
    • Panayiotidis P, Jones D, Ganeshaguru K, Foroni L and Hoffbrand AV: Human bone marrow stromal cells prevent apoptosis and support the survival of chronic lymphocytic leukaemia cells in vitro. Br J Haematol 92: 97-103, 1996.
    • (1996) Br J Haematol , vol.92 , pp. 97-103
    • Panayiotidis, P.1    Jones, D.2    Ganeshaguru, K.3    Foroni, L.4    Hoffbrand, A.V.5
  • 114
    • 0036464610 scopus 로고    scopus 로고
    • Distinctive features of "nurse-like" cells that differentiate in the context of chronic lymhpocytic leukaemia
    • Tsukada N, Burger JA, Zwaifler NJ and Kipps TJ: Distinctive features of "nurse-like" cells that differentiate in the context of chronic lymhpocytic leukaemia. Blood 99: 1030-1037, 2002.
    • (2002) Blood , vol.99 , pp. 1030-1037
    • Tsukada, N.1    Burger, J.A.2    Zwaifler, N.J.3    Kipps, T.J.4
  • 116
    • 0034329298 scopus 로고    scopus 로고
    • In vitro and in vivo production of vascular endothelial growth factor by chronic lymphocytic leukaemia cells
    • Chen H, Treweeke AT, West DC, Till KJ, Cawley JC, Zuzel M and Toh CH: In vitro and in vivo production of vascular endothelial growth factor by chronic lymphocytic leukaemia cells. Blood 96: 3181-3187, 2000.
    • (2000) Blood , vol.96 , pp. 3181-3187
    • Chen, H.1    Treweeke, A.T.2    West, D.C.3    Till, K.J.4    Cawley, J.C.5    Zuzel, M.6    Toh, C.H.7
  • 117
    • 3242703539 scopus 로고    scopus 로고
    • VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG) in B-cell chronic lymphocytic leukaemia
    • Lee YK, Bone ND, Strege AK, Shanafelt TD, Jelinek DF and Kay NE: VEGF receptor phosphorylation status and apoptosis is modulated by a green tea component, epigallocatechin-3-gallate (EGCG) in B-cell chronic lymphocytic leukaemia. Blood 104: 788-794, 2004.
    • (2004) Blood , vol.104 , pp. 788-794
    • Lee, Y.K.1    Bone, N.D.2    Strege, A.K.3    Shanafelt, T.D.4    Jelinek, D.F.5    Kay, N.E.6
  • 118
    • 0036119210 scopus 로고    scopus 로고
    • Chemokine receptors and stromal cells in the homing and homeostasis of chronic lymhpocytic leukaemia
    • Burger JA and Kipps TJ: Chemokine receptors and stromal cells in the homing and homeostasis of chronic lymhpocytic leukaemia. Leuk Lymphoma 43: 461-466, 2004.
    • (2004) Leuk Lymphoma , vol.43 , pp. 461-466
    • Burger, J.A.1    Kipps, T.J.2
  • 119
    • 0034051534 scopus 로고    scopus 로고
    • The indispensable role of microenvironment in the natural history of low-grade B-cell neoplasms
    • Ghia P and Caligaris-Cappio F: The indispensable role of microenvironment in the natural history of low-grade B-cell neoplasms. Adv Cancer Res 79: 157-173, 2000.
    • (2000) Adv Cancer Res , vol.79 , pp. 157-173
    • Ghia, P.1    Caligaris-Cappio, F.2
  • 120
    • 2942584865 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia: Revelations from the B-cell receptor
    • Stevenson FK and Caligaris-Cappio F: Chronic lymphocytic leukaemia: revelations from the B-cell receptor. Blood 103: 4389-4395, 2004.
    • (2004) Blood , vol.103 , pp. 4389-4395
    • Stevenson, F.K.1    Caligaris-Cappio, F.2
  • 121
    • 0028324454 scopus 로고
    • Molcular cloning and structure of a pre-B-cell growth-stimulating factor
    • Nagasawa T, Kikutani H and Kishimoto T: Molcular cloning and structure of a pre-B-cell growth-stimulating factor. Proc Natl Acad Sci USA 91: 2305-2309, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 2305-2309
    • Nagasawa, T.1    Kikutani, H.2    Kishimoto, T.3
  • 122
    • 0033119201 scopus 로고    scopus 로고
    • The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment
    • Ma Q, Jones D and Springer TA: The chemokine receptor CXCR4 is required for the retention of B lineage and granulocytic precursors within the bone marrow microenvironment. Immunity 10:463-471, 1999.
    • (1999) Immunity , vol.10 , pp. 463-471
    • Ma, Q.1    Jones, D.2    Springer, T.A.3
  • 123
    • 0033485625 scopus 로고    scopus 로고
    • Chronic lymphocytic leukaemia B-cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells
    • Burger JA, Burger M and Kipps TJ: Chronic lymphocytic leukaemia B-cells express functional CXCR4 chemokine receptors that mediate spontaneous migration beneath bone marrow stromal cells. Blood 94: 3658-3667, 1999.
    • (1999) Blood , vol.94 , pp. 3658-3667
    • Burger, J.A.1    Burger, M.2    Kipps, T.J.3
  • 124
    • 0344577963 scopus 로고    scopus 로고
    • Overexpression of the chemokine receptor CXCR4 in B-cell chronic lymphocytic leukaemia is associated with increased functional response to stromal cell-derived factor-1 (SDF-I)
    • Mohle R, Failenschmid C, Bautz F and Kanz L: Overexpression of the chemokine receptor CXCR4 in B-cell chronic lymphocytic leukaemia is associated with increased functional response to stromal cell-derived factor-1 (SDF-I). Leukaemia 13: 1954-1959, 1999.
    • (1999) Leukaemia , vol.13 , pp. 1954-1959
    • Mohle, R.1    Failenschmid, C.2    Bautz, F.3    Kanz, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.