VH mutation status, CD38 expression level, genomic aberrations, and survival in chronic lymphocytic leukemia

Blood

Volumn 100, Issue 4, 2002, Pages 1410-1416

  Kröber, Alexander ^a,b   Seiler, Till ^a,b   Benner, Axel ^a,b   Bullinger, Lars ^a,b   Brückle, Elsbeth ^a,b   Lichter, Peter ^a,b   Döhner, Hartmut ^a,b   Stilgenbauer, Stephan ^a,b  

^a UNIVERSITY OF ULM   (Germany)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD38 ANTIGEN; IMMUNOGLOBULIN;

ADULT; AGED; ANTIGEN EXPRESSION; ARTICLE; CANCER SURVIVAL; CHRONIC LYMPHATIC LEUKEMIA; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENCE IN SITU HYBRIDIZATION; GENOMICS; HUMAN; LEUKEMOGENESIS; MAJOR CLINICAL STUDY; MALE; MUTATION; OUTCOMES RESEARCH; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS;

EID: 0037103212     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood.v100.4.1410.h81602001410_1410_1416     Document Type: Article

References (25)

1. Chronic lymphocytic leukemia
2. Chronic lymphocytic leukemia: Staging and prognostic factors
3. Clinical staging of chronic lymphocytic leukemia
4. A new prognostic classification of chronic lymphocytic leukemia derived from a multivariate survival analysis
5. Genomic aberrations and survival in chronic lymphocytic leukemia
6. p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression
7. p53 mutations in human lymphoid malignancies: Association with Burkitt lymphoma and chronic lymphocytic leukemia
8. p53 gene deletion predicts for poor survival and non-response to therapy with purine analogs In chronic B-cell leukemias
9. In B-cell chronic lymphocytic leukaemia chromosome 17 abnormalities and not trisomy 12 are the single most important cytogenetic abnormalities for the prognosis: A cytogenetic and immunophenotypic study of 480 unselected newly diagnosed patients
10. Cellular origin of human B-cell lymphomas
11. The pathogenesis of chronic lymphocytic leukemia: Analysis of the antibody repertoire
12. Chronic lymphocytic leukemia B cells express restricted sets of mutated and unmutated antigen receptors
13. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia
14. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
15. Immunoglobulin V genes and CD38 expression in CLL
16. CD38 expression is a poor predictor for VH gene mutational status and prognosis in chronic lymphocytic leukemia
17. CD38 expression and Ig VH gene mutation in B-cell chronic lymphocytic leukemia
18. CD38 expression as an important prognostic factor in B-cell chronic lymphocytic leukemia
19. Micromanipulation and PCR analysis of single cells from tissue sections
20. The human immunoglobulin VH repertoire
21. Censored distributions as a measure of follow-up in survival analyis
22. Maximally selected rank statistics
23. Regression models and life-tables
24. Prognostic factor studies