Comparison of bone marrow and peripheral blood ZAP-70 status examined by flow cytometric immunophenotyping in patients with chronic lymphocytic leukemia

Cytometry Part B - Clinical Cytometry

Volumn 70, Issue 4, 2006, Pages 319-320

  Sheridan, Rachel ^a   Mounajjed, Taofic ^a   Ehrmann, Diane E ^b   Hurtubise, Paul E ^a   Schrager, Jeffrey A ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b QUEST DIAGNOSTICS NICHOLS INSTITUTE   (United States)

Author keywords

Bone marrow; CLL; Flow cytometry; Peripheral blood; ZAP 70

Indexed keywords

CD19 ANTIGEN; IMMUNOGLOBULIN HEAVY CHAIN; PROTEIN KINASE ZAP 70; PROTEIN TYROSINE KINASE; TUMOR MARKER;

ARTICLE; B LYMPHOCYTE; BONE MARROW; CANCER PATIENT; CHRONIC LYMPHATIC LEUKEMIA; COMPARATIVE STUDY; CONTROLLED STUDY; FLOW CYTOMETRY; GENE EXPRESSION PROFILING; GENE MUTATION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; IMMUNOPHENOTYPING; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; STATISTICAL ANALYSIS; TUMOR CELL;

EID: 33748508638     PISSN: 15524949     EISSN: 15524957     Source Type: Journal    
DOI: 10.1002/cyto.b.20128     Document Type: Article

References (4)

1. Wiestner A, et al. ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile. Blood 2003;101:4944-4951.
2. Gibbs G, et al. Comparison of flow cytometric methods for the measurement of ZAP-70 expression in a routine diagnostic laboratory. Clin Lab Haematol 2005;27:258-266.
3. Schroers R. et al. Combined analysis of ZAP-70 and CD38 expression as a predictor of disease progression in B-cell chronic lymphocytic leukemia. Leukemia 2005;19:750-758.
4. Cutrona G, et al. B lymphocytes in humans express ZAP-70 when - activated in vivo. Eur J Immunol 2006;36:558-569.