Everything you ever wanted to know about ZAP-70;Tout ce que vous avez toujours voulu savoir sur la protéine ZAP-70

Medecine/Sciences

Volumn 21, Issue 2, 2005, Pages 150-155

  Hivros, Claire ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN; GROWTH FACTOR RECEPTOR BOUND PROTEIN 2; LAT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHOLIPASE C GAMMA; PROTEIN KINASE ZAP 70; T LYMPHOCYTE RECEPTOR;

AUTOIMMUNE DISEASE; B CELL LEUKEMIA; B LYMPHOCYTE; CELL MATURATION; GENE; GENE MUTATION; HUMAN; IMMUNE DEFICIENCY; IMMUNE RESPONSE; IMMUNOLOGICAL TOLERANCE; NATURAL KILLER CELL; PROGNOSIS; PROTEIN EXPRESSION; REVIEW; T LYMPHOCYTE ACTIVATION; THYMOCYTE; ZAP 70 GENE;

EID: 13944261903     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/2005212150     Document Type: Review

References (30)

1. Chan AC, Iwashima M, Turck CW, Weiss A. ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain. Cell 1992; 71: 649-62.
2. Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Cell 1994; 76: 263-74.
3. + thymic selection in humans lacking zap-70 kinase. Cell 1994; 76: 947-58.
4. Elder ME, Lin D, Clever J, et al. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase. Science 1994; 264: 1596-9.
5. Chan AC, Kadlecek TA, Elder ME, et al. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency. Science 1994; 264: 1599-601.
6. Hivroz C, Fischer A. Immunodeficiency diseases. Multiple roles for ZAP-70. Curr Biol 1994; 4: 731-3.
7. Steinberg M, Swainson L, Schwarz K, et al. Retrovirus-mediated transduction of primary ZAP-70-deficient human T cells results in the selective growth advantage of gene-corrected cells: implications for gene therapy. Gene Ther 2000; 7: 1392-40.
8. Matsuda S, Suzuki-Fujimoto T, Minowa A, et al. Temperature-sensitive ZAP70 mutants degrading through a proteasome-independent pathway. Restoration of a kinase domain mutant by Cdc37 J Biol Chem 1999; 274: 34515-8.
9. + T cells in peripheral blood and their skin infiltration in CD8 deficiency. Clin Exp Immunol 1999; 115: 124-30.
10. Williams BL, Schreiber KL, Zhang W, et al. Genetic evidence for differential coupling of Syk family kinases to the T-cell receptor: reconstitution studies in a ZAP-70-deficient Jurkat T-cell line. Mol Cell Biol 1998; 18: 1388-99.
11. Kadlecek TA, van Oers NS, Lefrancois L, et al. Differential requirements for ZAP-70 in TCR signaling and T cell development. J Immunol 1998; 161: 4688-94.
12. Meinl E, Lengenfelder D, Blank N, et al. Differential requirement of ZAP-70 for CD2-mediated activation pathways of mature human T cells. J Immunol 2000; 165: 3578-83.
13. 2+ mobilization and Erk activation in Jurkat T cells in response to T-cell antigen receptor ligation. Mol Cell Biol 2001; 21: 7137-49.
14. Zhang W, Sloan-Lancaster J, Kitchen J, et al. LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation. Cell 1998; 92: 83-92.
15. Wardenburg JB, Fu C, Jackman JK, et al. Phosphorylation of SLP-76 by the ZAP-70 protein-tyrosine kinase is required for T-cell receptor function. J Biol Chem 1996; 271: 19641-4.
16. Jordan MS, Singer AL, Koretzky GA. Adaptors as central mediators of signal transduction in immune cells. Nat Immunol 2003; 4: 110-6.
17. Goda S, Quale AC, Woods ML, et al. Control of TCR-mediated activation of beta 1 integrins by the ZAP-70 tyrosine kinase interdomain B region and the linker for activation of T cells adapter protein. J Immunol 2004; 172: 5379-87.
18. Blanchard N, Di Bartolo V, Hivroz C. In the immune synapse, ZAP-70 controls T cell polarization and recruitment of signaling proteins but not formation of the synaptic pattern. Immunity 2002; 17: 389-99.
19. van Der Merwe PA, Davis SJ. The immunological synapse: a multitasking system. Science 2002; 295: 1479-80.
20. Dumont C, Blanchard N, Di Bartolo V, et al. TCR/CD3 down-modulation and zeta degradation are regulated by ZAP-70. J Immunol 2002; 169: 1705-12.
21. Zhong L, Wu CH, Lee WH, Liu CP. Zeta-associated protein of 70 kDa (ZAP-70), but not Syk, tyrosine kinase can mediate apoptosis of T cells through the Fas/Fas ligand, caspase-8 and caspase-3 pathways, J Immunol 2004; 172: 1472-82.
22. Carpino N, Turner S, Mekala D, et al. Regulation of ZAP-70 activation and TCR signaling by two related proteins, Sts-1 and Sts-2. Immunity 2004; 20: 37-46.
23. Sakaguchi N, Takahashi T, Hata H, et al. Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice. Nature 2003; 426: 454-60.
24. Rosenwald A, Alizadeh AA, Widhopf G, et al. Relation of gene expression phenotype to immunoglobulin mutation genotype in B cell chronic lymphocytic leukemia. J Exp Med 2001; 194: 1639-47.
25. Orchard JA, Ibbotson RE, Davis Z, et al. ZAP-70 expression and prognosis in chronic lymphocytic leukaemia. Lancet 2004; 363: 105-11.
26. Chen L, Widhopf G, Huynh L, et al. Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood 2002; 100: 4609-14.
27. Turner M, Mee PJ, Costello PS, et al. Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature 1995; 378: 298-302.
28. Cheng AM, Rowley B, Pao W, et al. Syk tyrosine kinase required for mouse viability and B-cell development. Nature 1995; 378: 303-6.
29. Schweighoffer E, Vanes L, Mathiot A, et al. Unexpected requirement for ZAP-70 in pre-B cell development and allelic exclusion. Immunity 2003; 18: 523-33.
30. Elder ME, Skoda-Smith S, Kadlecek TA, et al. Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70. J Immunol 2001; 166: 656-61.