메뉴 건너뛰기




Volumn 61, Issue 2, 2009, Pages 167-176

MicroRNA and central nervous system

Author keywords

Agonaute family; Antagomir; Drosha; MiRNA; Non coding RNA

Indexed keywords

ARGONAUTE PROTEIN; MICRORNA; MICRORNA 134; POLYGLUTAMINE; RIBONUCLEASE III; UNCLASSIFIED DRUG;

EID: 60749129510     PISSN: 18816096     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (14)

References (78)
  • 1
    • 1842584883 scopus 로고    scopus 로고
    • RNA regulation: A new genetics?
    • Mattick JS: RNA regulation: a new genetics? Nature Rev Genet 5: 316-323, 2004
    • (2004) Nature Rev Genet , vol.5 , pp. 316-323
    • Mattick, J.S.1
  • 2
    • 51549106674 scopus 로고    scopus 로고
    • Small RNA regulators of gene expression
    • Neilson JR, Sharp PA: Small RNA regulators of gene expression. Cell 134: 899-902. 2008
    • (2008) Cell , vol.134 , pp. 899-902
    • Neilson, J.R.1    Sharp, P.A.2
  • 3
    • 14644393684 scopus 로고    scopus 로고
    • Perspective: Machines for RNAi
    • Tomari Y, Zamore PD: Perspective: machines for RNAi. Genes Dev 19: 517-529, 2005
    • (2005) Genes Dev , vol.19 , pp. 517-529
    • Tomari, Y.1    Zamore, P.D.2
  • 4
    • 0027751663 scopus 로고
    • The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
    • Lee RC, Feinbaum RL, Ambros V: The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell 75: 843-854, 1993
    • (1993) Cell , vol.75 , pp. 843-854
    • Lee, R.C.1    Feinbaum, R.L.2    Ambros, V.3
  • 7
    • 28944439309 scopus 로고    scopus 로고
    • Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution
    • ) Stark A, Brennecke J, Bushati N, Russell RB, Cohen SM: Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell. 123: 1133-1146, 2005
    • (2005) Cell , vol.123 , pp. 1133-1146
    • Stark, A.1    Brennecke, J.2    Bushati, N.3    Russell, R.B.4    Cohen, S.M.5
  • 8
    • 29144505309 scopus 로고    scopus 로고
    • The widespread impact of mammalian MicroRNAs on mRNA repression and evolution
    • ) Farh KK, Crimson A, Jan C, Lewis BP, Johnston WK, et al: The widespread impact of mammalian MicroRNAs on mRNA repression and evolution. Science 310: 1817-1821, 2005
    • (2005) Science , vol.310 , pp. 1817-1821
    • Farh, K.K.1    Crimson, A.2    Jan, C.3    Lewis, B.P.4    Johnston, W.K.5
  • 9
    • 44649124293 scopus 로고    scopus 로고
    • Small RNAs tell big stories in Whistler
    • ) Seila AC, Sharp PA: Small RNAs tell big stories in Whistler. Nat Cell Biol 10: 630-633, 2008
    • (2008) Nat Cell Biol , vol.10 , pp. 630-633
    • Seila, A.C.1    Sharp, P.A.2
  • 11
    • 34548537573 scopus 로고    scopus 로고
    • A MicroRNA feedback circuit in midbrain dopamine neurons
    • Kim J, Inoue K, Ishii J, Vanti WB, Voronov SV, et al: A MicroRNA feedback circuit in midbrain dopamine neurons. Science 317: 1220-1224, 2007
    • (2007) Science , vol.317 , pp. 1220-1224
    • Kim, J.1    Inoue, K.2    Ishii, J.3    Vanti, W.B.4    Voronov, S.V.5
  • 13
    • 6344281172 scopus 로고    scopus 로고
    • Identification of mammalian microRNA host genes and transcription units
    • Rodriguez A, Griffiths-Jones S, Ashurst JL, Bradley A: Identification of mammalian microRNA host genes and transcription units. Genome Res 14: 1902-1910, 2004
    • (2004) Genome Res , vol.14 , pp. 1902-1910
    • Rodriguez, A.1    Griffiths-Jones, S.2    Ashurst, J.L.3    Bradley, A.4
  • 15
    • 34047234690 scopus 로고    scopus 로고
    • Characterization and identification of microRNA core promoters in four model species
    • Zhou X, Ruan J, Wang G, Zhang W: Characterization and identification of microRNA core promoters in four model species. PLoS Comput Biol 3; e37, 2007
    • (2007) PLoS Comput Biol , vol.3
    • Zhou, X.1    Ruan, J.2    Wang, G.3    Zhang, W.4
  • 16
    • 33749598345 scopus 로고    scopus 로고
    • Epigenetic activation of tumor suppressor microRNAs in human cancer cells. Epigenetic activation of tumor suppressor microRNAs in human cancer cells
    • Saito Y, Jones PA: Epigenetic activation of tumor suppressor microRNAs in human cancer cells. Epigenetic activation of tumor suppressor microRNAs in human cancer cells. Cell Cycle 5: 2220-2222, 2006
    • (2006) Cell Cycle , vol.5 , pp. 2220-2222
    • Saito, Y.1    Jones, P.A.2
  • 17
    • 33846945735 scopus 로고    scopus 로고
    • Processing of intronic microRNAs
    • Kim YK, Kim VN: Processing of intronic microRNAs. EMBO J 26: 775-783, 2007
    • (2007) EMBO J , vol.26 , pp. 775-783
    • Kim, Y.K.1    Kim, V.N.2
  • 18
    • 33747334621 scopus 로고    scopus 로고
    • Extensive post-transcriptional regulation of microRNAs and its implications for cancer
    • Thomson JM, Newman M, Parker JS, Morin-Kensicki EM, Wright T, et al: Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev 20: 2202-2207, 2006
    • (2006) Genes Dev , vol.20 , pp. 2202-2207
    • Thomson, J.M.1    Newman, M.2    Parker, J.S.3    Morin-Kensicki, E.M.4    Wright, T.5
  • 19
    • 38049016849 scopus 로고    scopus 로고
    • Xenopus microRNA genes are predominantly located within introns and are differentially expressed in adult frog tissues via post-transcriptional regulation
    • Tang GQ, Maxwell ES: Xenopus microRNA genes are predominantly located within introns and are differentially expressed in adult frog tissues via post-transcriptional regulation. Genome Res 18: 104-112, 2008
    • (2008) Genome Res , vol.18 , pp. 104-112
    • Tang, G.Q.1    Maxwell, E.S.2
  • 20
    • 40849108663 scopus 로고    scopus 로고
    • Selective blockade of microRNA processing by Lin28
    • Viswanathan SR, Daley GQ, Gregory RI: Selective blockade of microRNA processing by Lin28. Science 320: 97-100, 2008
    • (2008) Science , vol.320 , pp. 97-100
    • Viswanathan, S.R.1    Daley, G.Q.2    Gregory, R.I.3
  • 21
    • 34447107760 scopus 로고    scopus 로고
    • The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila
    • Okamura K. Hagen JW, Duan H, Tyler DM, Lai EC: The mirtron pathway generates microRNA-class regulatory RNAs in Drosophila. Cell 130: 89-100, 2007
    • (2007) Cell , vol.130 , pp. 89-100
    • Okamura, K.1    Hagen, J.W.2    Duan, H.3    Tyler, D.M.4    Lai, E.C.5
  • 23
    • 1642499415 scopus 로고    scopus 로고
    • Exportin 5 is a RanGTP-dependentdsRNA-binding protein that mediates nuclear export of pre-miRNAs
    • Bohnsack MT, Czaplinski K, Gorlich D: Exportin 5 is a RanGTP-dependentdsRNA-binding protein that mediates nuclear export of pre-miRNAs. RNA 10: 185-191, 2004
    • (2004) RNA , vol.10 , pp. 185-191
    • Bohnsack, M.T.1    Czaplinski, K.2    Gorlich, D.3
  • 24
    • 23644433363 scopus 로고    scopus 로고
    • TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
    • Chendrimada TP, Gregory RI, Kumaraswamy E, Norman J, Cooch N, et al: TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436: 740-744, 2005
    • (2005) Nature , vol.436 , pp. 740-744
    • Chendrimada, T.P.1    Gregory, R.I.2    Kumaraswamy, E.3    Norman, J.4    Cooch, N.5
  • 25
    • 0034673638 scopus 로고    scopus 로고
    • An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells
    • Hammond SM, Bernstein E, Beach D, Hannon GJ: An RNA-directed nuclease mediates post-transcriptional gene silencing in Drosophila cells. Nature 404: 293-296, 2000
    • (2000) Nature , vol.404 , pp. 293-296
    • Hammond, S.M.1    Bernstein, E.2    Beach, D.3    Hannon, G.J.4
  • 26
    • 0036570589 scopus 로고    scopus 로고
    • Why do miRNAs live in the miRNP?
    • Schwarz DS, Zamore PD: Why do miRNAs live in the miRNP? Genes Dev 16: 1025-1031, 2002
    • (2002) Genes Dev , vol.16 , pp. 1025-1031
    • Schwarz, D.S.1    Zamore, P.D.2
  • 27
    • 13244278197 scopus 로고    scopus 로고
    • siRNA and miRNA: An insight into RISCs
    • Tang G: siRNA and miRNA: an insight into RISCs. Trends Biochem Sci 30: 106-114, 2005
    • (2005) Trends Biochem Sci , vol.30 , pp. 106-114
    • Tang, G.1
  • 31
    • 11844278458 scopus 로고    scopus 로고
    • Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
    • Lewis BP, Burge C, Bartel DP: Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell 120: 15-20, 2005
    • (2005) Cell , vol.120 , pp. 15-20
    • Lewis, B.P.1    Burge, C.2    Bartel, D.P.3
  • 32
    • 34250805982 scopus 로고    scopus 로고
    • MicroRNA targeting specificity in mammals: Determinants beyond seed pairing
    • Grimson A, Farh KK, Johnston WK, Garrett-Engele P, Lim LP, et al: MicroRNA targeting specificity in mammals: determinants beyond seed pairing. Mol Cell 27: 91-105, 2007
    • (2007) Mol Cell , vol.27 , pp. 91-105
    • Grimson, A.1    Farh, K.K.2    Johnston, W.K.3    Garrett-Engele, P.4    Lim, L.P.5
  • 33
    • 35548996307 scopus 로고    scopus 로고
    • Determinants of targeting by endogenous and exogenous microRNAs and siRNAs
    • Nielsen CB, Shomron N, Sandberg R, Hornstein E, Kitzman J, et al: Determinants of targeting by endogenous and exogenous microRNAs and siRNAs. RNA 13, 1894-1910, 2007
    • (2007) RNA , vol.13 , pp. 1894-1910
    • Nielsen, C.B.1    Shomron, N.2    Sandberg, R.3    Hornstein, E.4    Kitzman, J.5
  • 34
    • 41649115420 scopus 로고    scopus 로고
    • GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay
    • Eulalio A, Huntzinger E, Izaurralde E: GW182 interaction with Argonaute is essential for miRNA-mediated translational repression and mRNA decay. Nat Struct Mol Biol 15: 346-53, 2008
    • (2008) Nat Struct Mol Biol , vol.15 , pp. 346-353
    • Eulalio, A.1    Huntzinger, E.2    Izaurralde, E.3
  • 35
    • 33645124258 scopus 로고    scopus 로고
    • Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs
    • Giraldez AJ, Mishima Y, Rihel J, Grocock RJ, Van Dongen S, et al: Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science 312: 75-79, 2006
    • (2006) Science , vol.312 , pp. 75-79
    • Giraldez, A.J.1    Mishima, Y.2    Rihel, J.3    Grocock, R.J.4    Van Dongen, S.5
  • 36
    • 33845353746 scopus 로고    scopus 로고
    • Evidence that microRNAs are associated with translating messenger RNAs in human cells
    • Maroney PA, Yu Y, Fisher J, Nilsen T: Evidence that microRNAs are associated with translating messenger RNAs in human cells. Nature Struct Mol Biol 13: 1102-1107, 2006
    • (2006) Nature Struct Mol Biol , vol.13 , pp. 1102-1107
    • Maroney, P.A.1    Yu, Y.2    Fisher, J.3    Nilsen, T.4
  • 37
    • 33845354027 scopus 로고    scopus 로고
    • Humanlet-7a miRNA blocks protein production on actively translating polyribosomes
    • Nottrott S, Simard MJ, Richter JD: Humanlet-7a miRNA blocks protein production on actively translating polyribosomes. Nature Struct Mol Biol 13: 1108-1114, 2006
    • (2006) Nature Struct Mol Biol , vol.13 , pp. 1108-1114
    • Nottrott, S.1    Simard, M.J.2    Richter, J.D.3
  • 38
    • 51349150703 scopus 로고    scopus 로고
    • Small RNAs: The seeds of silence
    • Mourelatos Z: Small RNAs: The seeds of silence. Nature 455: 44-45, 2008
    • (2008) Nature , vol.455 , pp. 44-45
    • Mourelatos, Z.1
  • 39
    • 34447642555 scopus 로고    scopus 로고
    • Sorting of Drosophila small silencing RNAs
    • Tomari Y, Du T, Zamore PD: Sorting of Drosophila small silencing RNAs. Cell 130: 299-308, 2007
    • (2007) Cell , vol.130 , pp. 299-308
    • Tomari, Y.1    Du, T.2    Zamore, P.D.3
  • 42
    • 33645124258 scopus 로고    scopus 로고
    • Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs
    • Giraldez AJ, Mishima Y, Rihel J, Grocock RJ, Van Dongen S, et al: Zebrafish MiR-430 promotes deadenylation and clearance of maternal mRNAs. Science 312: 75-79, 2006
    • (2006) Science , vol.312 , pp. 75-79
    • Giraldez, A.J.1    Mishima, Y.2    Rihel, J.3    Grocock, R.J.4    Van Dongen, S.5
  • 43
    • 0037466486 scopus 로고    scopus 로고
    • Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region
    • Shiohama A, Sasaki T, Noda S, Minoshima S, Shim-izu N: Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region, Biochem Biophys Res Commun 304: 184-190, 2003
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 184-190
    • Shiohama, A.1    Sasaki, T.2    Noda, S.3    Minoshima, S.4    Shim-izu, N.5
  • 45
    • 34548773918 scopus 로고    scopus 로고
    • Cloning and identification of novel MicroRNAs from rat hippocampus
    • He X, Zhang Q, Liu Y, Pan X: Cloning and identification of novel MicroRNAs from rat hippocampus. Acta Biochim Biophys Sin (Shanghai) 39: 708-714, 2007
    • (2007) Acta Biochim Biophys Sin (Shanghai) , vol.39 , pp. 708-714
    • He, X.1    Zhang, Q.2    Liu, Y.3    Pan, X.4
  • 47
    • 33144481470 scopus 로고    scopus 로고
    • Reciprocal actions of REST and a microRNA promote neuronal identity
    • Conaco C, Otto S, Han JJ, Mandel G: Reciprocal actions of REST and a microRNA promote neuronal identity. Proc Natl Acad Sci USA 103: 2422-2427, 2006
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 2422-2427
    • Conaco, C.1    Otto, S.2    Han, J.J.3    Mandel, G.4
  • 48
    • 1942494040 scopus 로고    scopus 로고
    • Expression profiling of mammalian microRNA suncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
    • Sempere LF, Freemantle S, Pitha-Rowe I, Moss E, DmitrovskyE, et al: Expression profiling of mammalian microRNA suncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation. Genome Biol 5: R13, 2004
    • (2004) Genome Biol , vol.5
    • Sempere, L.F.1    Freemantle, S.2    Pitha-Rowe, I.3    Moss, E.4    DmitrovskyE5
  • 49
    • 33744973775 scopus 로고    scopus 로고
    • Relief of microRNA-mediated trans-lational repression in human cells subjected to stress
    • Bhattacharyya SN, Habermacher R, Martine U, Closs EI, Filipowicz W: Relief of microRNA-mediated trans-lational repression in human cells subjected to stress. Cell 125: 1111-1124, 2006
    • (2006) Cell , vol.125 , pp. 1111-1124
    • Bhattacharyya, S.N.1    Habermacher, R.2    Martine, U.3    Closs, E.I.4    Filipowicz, W.5
  • 50
    • 34548177451 scopus 로고    scopus 로고
    • Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells
    • Lukiw WJ, Pogue Al: Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J Inorg Biochem 101:1265-1269, 2007
    • (2007) J Inorg Biochem , vol.101 , pp. 1265-1269
    • Lukiw, W.J.1    Pogue, A.2
  • 51
    • 34347263491 scopus 로고    scopus 로고
    • Small RNAs as big players in plant abiotic stress responses and nutrient deprivation
    • Sunkar R, Chinnusamy V, Zhu J, Zhu JK: Small RNAs as big players in plant abiotic stress responses and nutrient deprivation. Trends Plant Sci 12: 301-309, 2007
    • (2007) Trends Plant Sci , vol.12 , pp. 301-309
    • Sunkar, R.1    Chinnusamy, V.2    Zhu, J.3    Zhu, J.K.4
  • 53
    • 13944282215 scopus 로고    scopus 로고
    • Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs
    • Lim LP, Lau NC, Garrett-Engele P, Grimson A, Schelter JM, et al: Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs. Nature 433: 769-773, 2005
    • (2005) Nature , vol.433 , pp. 769-773
    • Lim, L.P.1    Lau, N.C.2    Garrett-Engele, P.3    Grimson, A.4    Schelter, J.M.5
  • 55
    • 33749078547 scopus 로고    scopus 로고
    • MicroRNA pathways modulate polyglutamine-induced neurodegeneration
    • Bilen J, Liu N, Burnett BG, Pittman RN, Bonini NM: MicroRNA pathways modulate polyglutamine-induced neurodegeneration. Mol Cell 24: 157-163, 2006
    • (2006) Mol Cell , vol.24 , pp. 157-163
    • Bilen, J.1    Liu, N.2    Burnett, B.G.3    Pittman, R.N.4    Bonini, N.M.5
  • 58
    • 26844498125 scopus 로고    scopus 로고
    • Sequence variants in SLITRK1 are associated with Tourette's syndrome
    • Abelson JF, Kwan KY, O'Roak BJ, Baek DY, Stillman AA, et al: Sequence variants in SLITRK1 are associated with Tourette's syndrome. Science 310: 317-320, 2005
    • (2005) Science , vol.310 , pp. 317-320
    • Abelson, J.F.1    Kwan, K.Y.2    O'Roak, B.J.3    Baek, D.Y.4    Stillman, A.A.5
  • 59
    • 44049108170 scopus 로고    scopus 로고
    • Loss of microRNA cluster miR-29a/b-l in sporadic Alzheimer's disease correlates with increased BACEl/beta-secretase expression
    • Hebert SS, Horré K, Nicolaï L, Papadopoulou AS, Mandemakers W, et al: Loss of microRNA cluster miR-29a/b-l in sporadic Alzheimer's disease correlates with increased BACEl/beta-secretase expression. Proc Natl Acad Sci USA 105: 6415-6420, 2008
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 6415-6420
    • Hebert, S.S.1    Horré, K.2    Nicolaï, L.3    Papadopoulou, A.S.4    Mandemakers, W.5
  • 60
    • 38749095507 scopus 로고    scopus 로고
    • The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1
    • Wang WX, Rajeev BW, Stromberg AJ, Ren N, Tang G, et al: The expression of microRNA miR-107 decreases early in Alzheimer's disease and may accelerate disease progression through regulation of beta-site amyloid precursor protein-cleaving enzyme 1. J Neurosci 28: 1213-1223, 2008
    • (2008) J Neurosci , vol.28 , pp. 1213-1223
    • Wang, W.X.1    Rajeev, B.W.2    Stromberg, A.J.3    Ren, N.4    Tang, G.5
  • 61
    • 33847203593 scopus 로고    scopus 로고
    • MicroRNA speciation in fetal, adult and Alzheimer's disease hippocampus
    • Lukiw WJ: MicroRNA speciation in fetal, adult and Alzheimer's disease hippocampus. Neuroreport 18: 297-300, 2007
    • (2007) Neuroreport , vol.18 , pp. 297-300
    • Lukiw, W.J.1
  • 62
    • 34548177451 scopus 로고    scopus 로고
    • Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells
    • Lukiw WJ, Pogue Al: Induction of specific micro RNA (miRNA) species by ROS-generating metal sulfates in primary human brain cells. J Inorg Biochem 101:1265-1269, 2007
    • (2007) J Inorg Biochem , vol.101 , pp. 1265-1269
    • Lukiw, W.J.1    Pogue, A.2
  • 63
    • 34848927455 scopus 로고    scopus 로고
    • The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila
    • Karres JS, Hilgers V, Carrera I, Treisman J, Cohen SM: The conserved microRNA miR-8 tunes atrophin levels to prevent neurodegeneration in Drosophila. Cell 131: 136-145, 2007
    • (2007) Cell , vol.131 , pp. 136-145
    • Karres, J.S.1    Hilgers, V.2    Carrera, I.3    Treisman, J.4    Cohen, S.M.5
  • 64
    • 52949137369 scopus 로고    scopus 로고
    • miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis
    • Lee Y, Samaco RC, Gatchel JR, Thaller C, Orr HT, et al: miR-19, miR-101 and miR-130 co-regulate ATXN1 levels to potentially modulate SCA1 pathogenesis. Nat Neurosci 11: 1137-1139, 2008
    • (2008) Nat Neurosci , vol.11 , pp. 1137-1139
    • Lee, Y.1    Samaco, R.C.2    Gatchel, J.R.3    Thaller, C.4    Orr, H.T.5
  • 65
    • 33749078547 scopus 로고    scopus 로고
    • MicroRNA pathways modulate polyglutamine-induced neurodegeneration
    • Bilen J, Liu N, Burnett BG, Pittman RN, Bonini NM: MicroRNA pathways modulate polyglutamine-induced neurodegeneration. Mol Cell. 24: 157-163, 2006
    • (2006) Mol Cell , vol.24 , pp. 157-163
    • Bilen, J.1    Liu, N.2    Burnett, B.G.3    Pittman, R.N.4    Bonini, N.M.5
  • 66
    • 36349032759 scopus 로고    scopus 로고
    • MicroRNAs in disease and potential therapeutic applications
    • Soifer HS, Rossi JJ, Saetrom P: MicroRNAs in disease and potential therapeutic applications. Mol Ther 15: 2070-2079, 2007
    • (2007) Mol Ther , vol.15 , pp. 2070-2079
    • Soifer, H.S.1    Rossi, J.J.2    Saetrom, P.3
  • 68
    • 42249093319 scopus 로고    scopus 로고
    • LNA-mediated microRNA silencing in non-human primates
    • Elmén J, Lindow M, Schütz S, Lawrence M, Petri A, et al: LNA-mediated microRNA silencing in non-human primates. Nature 452: 896-899, 2008
    • (2008) Nature , vol.452 , pp. 896-899
    • Elmén, J.1    Lindow, M.2    Schütz, S.3    Lawrence, M.4    Petri, A.5
  • 69
    • 34247382522 scopus 로고    scopus 로고
    • Double-stranded regions are essential design components of potent inhibitors of RISC function
    • Vermeulen A, Robertson B, Dalby AB, Marshall WS, Karpilow J, et al: Double-stranded regions are essential design components of potent inhibitors of RISC function. RNA 13: 723-730, 2007
    • (2007) RNA , vol.13 , pp. 723-730
    • Vermeulen, A.1    Robertson, B.2    Dalby, A.B.3    Marshall, W.S.4    Karpilow, J.5
  • 73
    • 0036726313 scopus 로고    scopus 로고
    • Stable suppression of tumorigenicity by virus-mediated RNA interference
    • Brummelkamp TR, Bernards R, Agami R: Stable suppression of tumorigenicity by virus-mediated RNA interference. Cancer Cell 2: 243-247, 2002
    • (2002) Cancer Cell , vol.2 , pp. 243-247
    • Brummelkamp, T.R.1    Bernards, R.2    Agami, R.3
  • 74
    • 0036294527 scopus 로고    scopus 로고
    • Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells
    • Zeng Y, Wagner EJ, Cullen BR: Both natural and designed micro RNAs can inhibit the expression of cognate mRNAs when expressed in human cells. Mol Cell 9: 1327-1333, 2002
    • (2002) Mol Cell , vol.9 , pp. 1327-1333
    • Zeng, Y.1    Wagner, E.J.2    Cullen, B.R.3
  • 75
    • 33745299723 scopus 로고    scopus 로고
    • Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways
    • Grimm D, Streetz KL, Jopling CL, Storm TA, Pandey K, et al: Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways. Nature 441: 537-541, 2006
    • (2006) Nature , vol.441 , pp. 537-541
    • Grimm, D.1    Streetz, K.L.2    Jopling, C.L.3    Storm, T.A.4    Pandey, K.5
  • 76
    • 50549092566 scopus 로고    scopus 로고
    • tissue-specific pol II promoter is an effective and safe RNAi therapeutic
    • Giering JC, Grimm D, Storm TA, Kay MA: tissue-specific pol II promoter is an effective and safe RNAi therapeutic. Mol Ther 16: 1630-1636, 2008
    • (2008) Mol Ther , vol.16 , pp. 1630-1636
    • Giering, J.C.1    Grimm, D.2    Storm, T.A.3    Kay, M.A.4
  • 77
    • 44449121785 scopus 로고    scopus 로고
    • Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: Implications for the therapeutic development of RNAi
    • McBride JL, Boudreau RL, Harper SQ, Staber PD, Monteys AM, et al: Artificial miRNAs mitigate shRNA-mediated toxicity in the brain: implications for the therapeutic development of RNAi. Proc Natl Acad Sci USA 105: 5868-5873, 2008
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 5868-5873
    • McBride, J.L.1    Boudreau, R.L.2    Harper, S.Q.3    Staber, P.D.4    Monteys, A.M.5
  • 78
    • 0038347805 scopus 로고    scopus 로고
    • Transcriptional targeting in cancer gene therapy
    • Robson, T and Hirst, DG: Transcriptional targeting in cancer gene therapy. J Biomed Biotechnol 2003: 110-137, 2003
    • (2003) J Biomed Biotechnol , vol.2003 , pp. 110-137
    • Robson, T.1    Hirst, D.G.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.