Enhanced cellular uptake and cytotoxicity studies of organometallic bioconjugates of the NLS peptide in hep G2 cells

ChemBioChem

Volumn 10, Issue 3, 2009, Pages 493-502

  Noor, Fozia ^a   Kinscherf, Ralf ^b   Bonaterra, Gabriel A ^b   Walczak, Steffen ^c   Wölfl, Stefan ^c   Metzler Nolte, Nils ^d  

^a SAARLAND UNIVERSITY   (Germany)

^b Centre for Biomedicine and Medical Technology Mannheim CBTM   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d RUHR UNIVERSITY BOCHUM   (Germany)

Author keywords

Bioconjugate; Bioinorganic chemistry; Cell penetrating peptides; Metallocenes; Nuclear delivery; Peptides

Indexed keywords

COBALTOCENIUM NUCLEAR LOCALIZATION SIGNAL PEPTIDE BIOCONJUGATE; FERROCENE NUCLEAR LOCALIZATION SIGNAL PEPTIDE BIOCONJUGATE; METALLOCENE NUCLEAR LOCALIZATION SIGNAL PEPTIDE BIOCONJUGATE; ORGANOMETALLIC COMPOUND; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; CELL STRAIN HEPG2; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOPLASM; DRUG CYTOTOXICITY; DRUG DISTRIBUTION; DRUG POTENCY; DRUG SYNTHESIS; DRUG TRANSPORT; DRUG UPTAKE; ENDOSOME; FLUORESCENCE MICROSCOPY; GENOTOXICITY; HUMAN; HUMAN CELL; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; SOLID PHASE SYNTHESIS;

AMINO ACID SEQUENCE; BIOLOGICAL TRANSPORT; CELL LINE; HUMANS; MOLECULAR SEQUENCE DATA; MOLECULAR STRUCTURE; NUCLEAR LOCALIZATION SIGNALS; ORGANOMETALLIC COMPOUNDS;

EID: 60349086381     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.200800469     Document Type: Article

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