Intracellular siRNA and precursor miRNA trafficking using bioresponsive copolypeptides

Journal of Gene Medicine

Volumn 10, Issue 1, 2008, Pages 81-93

  Rahbek, Ulrik L ^a   Howard, Kenneth A ^a   Oupicky, David ^b   Manickam, Devika S ^b   Dong, Mingdong ^a   Nielsen, Anne F ^a   Hansen, Thomas B ^a   Basenbacher, Flemming ^a   Kjems, Jørgens ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b WAYNE STATE UNIVERSITY   (United States)

Author keywords

Copolypeptides; Nuclear trafficking; Polyplexes; pri miRNA; siRNA

Indexed keywords

COPOLYMER; DICER; DROSHA; DRUG CARRIER; ELONGATION FACTOR 1ALPHA; ENHANCED GREEN FLUORESCENT PROTEIN; HISTIDINE; MICRORNA; POLYPEPTIDE; RIBONUCLEASE III; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; ATOMIC FORCE MICROSCOPY; CANCER CELL CULTURE; CELL TRANSPORT; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG CYTOTOXICITY; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; GENE SILENCING; HUMAN; HUMAN CELL; NONVIRAL GENE DELIVERY SYSTEM; NORTHERN BLOTTING; NUCLEAR LOCALIZATION SIGNAL; PHOTON CORRELATION SPECTROSCOPY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA PROCESSING; RNA TRANSPORT;

CELL COMPARTMENTATION; CELL DEATH; CELL NUCLEUS; DITHIOTHREITOL; GENE EXPRESSION REGULATION, NEOPLASTIC; HELA CELLS; HUMANS; MICRORNAS; MOLECULAR WEIGHT; OXIDATION-REDUCTION; PEPTIDES; RNA INTERFERENCE; RNA PRECURSORS; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA TRANSPORT; RNA, SMALL INTERFERING;

EID: 38349096679     PISSN: 1099498X     EISSN: 15212254     Source Type: Journal    
DOI: 10.1002/jgm.1120     Document Type: Article

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