Cellular Internalization of Human Calcitonin Derived Peptides in MDCK Monolayers: A Comparative Study with Tat(47-57) and Penetratin(43-58)

Pharmaceutical Research

Volumn 21, Issue 1, 2004, Pages 33-42

  Tréhin, Rachel ^a   Krauss, Ulrike ^b   Muff, Roman ^c   Meinecke, Martina ^a   Beck Sickinger, Annette G ^b   Merkle, Hans P ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Cell penetrating peptides; Cell uptake; Endocytosis; Human calcitonin; MDCK

Indexed keywords

AMINO ACID; CALCITONIN DERIVATIVE; CARBONYL DERIVATIVE; FLUORESCENT DYE; LACTATE DEHYDROGENASE; LYSINE; PENETRATIN; PEPTIDE; PROLINE; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BIOLOGICAL MODEL; CELL MEMBRANE PERMEABILITY; CELL STRAIN; CELL TRANSPORT; CELL VIABILITY; CELLULAR DISTRIBUTION; CHEMISTRY; COMPARATIVE STUDY; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DERIVATIZATION; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG UPTAKE; ENDOCYTOSIS; EPITHELIUM; HELA CELL; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN TRANSPORT; TEMPERATURE DEPENDENCE; TIME; TOXICITY;

AMINO ACID SEQUENCE; ANIMALS; BIOLOGICAL TRANSPORT; CALCITONIN; CARRIER PROTEINS; CELL LINE; CELL MEMBRANE PERMEABILITY; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCYTOSIS; GENE PRODUCTS, TAT; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS;

EID: 1642457360     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/B:PHAM.0000012149.83119.bf     Document Type: Article

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