DNA damage alters DNA polymerase δ to a form that exhibits increased discrimination against modified template bases and mismatched primers

Nucleic Acids Research

Volumn 37, Issue 2, 2009, Pages 647-657

  Meng, Xiao ^a   Zhou, Yajing ^a   Zhang, Sufang ^a   Lee, Ernest Y C ^a   Frick, David N ^a   Lee, Marietta Y W T ^a  

^a NEW YORK MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 O METHYLGUANINE; 8 HYDROXYGUANINE; DNA; DNA DIRECTED DNA POLYMERASE DELTA; DNA DIRECTED DNA POLYMERASE DELTA3; DNA DIRECTED DNA POLYMERASE DELTA4; DNA POLYMERASE; EXONUCLEASE; THYMINE; UNCLASSIFIED DRUG;

ARTICLE; BASE MISPAIRING; CATALYSIS; CONTROLLED STUDY; DNA BASE COMPOSITION; DNA DAMAGE; DNA MODIFICATION; DNA REPAIR; DNA SYNTHESIS; DNA TEMPLATE; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME SUBUNIT; HUMAN; HUMAN CELL; MISMATCH REPAIR; NUCLEIC ACID BASE SUBSTITUTION; PRIORITY JOURNAL;

BASE PAIR MISMATCH; DNA; DNA DAMAGE; DNA POLYMERASE III; DNA PRIMERS; EXODEOXYRIBONUCLEASES; HELA CELLS; HUMANS; MUTATION; NUCLEOTIDES; PROTEIN SUBUNITS; PYRIMIDINE DIMERS; RECOMBINANT PROTEINS; TEMPLATES, GENETIC; ULTRAVIOLET RAYS;

EID: 59649103417     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn1000     Document Type: Article

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