Essential role of phosphoinositide 3-kinase gamma in eosinophil chemotaxis within acute pulmonary inflammation

Immunology

Volumn 126, Issue 3, 2009, Pages 413-422

  Thomas, Matthew ^a   Edwards, Matthew J ^a   Sawicka, Elzbieta ^a   Duggan, Nicholas ^a   Hirsch, Emilio ^b   Wymann, Matthias P ^c   Owen, Charles ^a   Trifilieff, Alexandre ^a   Walker, Christoph ^a   Westwick, John ^a   Finan, Peter ^a  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b UNIVERSITY OF TURIN   (Italy)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Asthma; Chemokines; Lipid mediators; Transgenic knockout

Indexed keywords

CHEMOKINE; IMMUNOGLOBULIN; OVALBUMIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; UNCLASSIFIED DRUG;

ACUTE DISEASE; AEROSOL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASTHMA; CELL INFILTRATION; CELL PROLIFERATION; CELL STRAIN; CHEMOTAXIS; CONTROLLED STUDY; EFFECTOR CELL; EOSINOPHIL; EOSINOPHILIA; FEMALE; IMMUNE RESPONSE; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; KNOCKOUT MOUSE; LUNG LAVAGE; LYMPHOCYTE PROLIFERATION; MACROPHAGE; MALE; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; STRAIN DIFFERENCE; T LYMPHOCYTE; WILD TYPE;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ACUTE DISEASE; ANIMALS; ASTHMA; B-LYMPHOCYTES; BRONCHOALVEOLAR LAVAGE FLUID; CD4-POSITIVE T-LYMPHOCYTES; CHEMOTAXIS, LEUKOCYTE; CYTOKINES; DISEASE MODELS, ANIMAL; EOSINOPHILIA; EOSINOPHILS; EPITOPES, T-LYMPHOCYTE; FEMALE; ISOENZYMES; MALE; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; OVALBUMIN; PNEUMONIA;

EID: 59449107435     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2008.02908.x     Document Type: Article

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