Adult-specific over-expression of the Drosophila genes magu and hebe increases life span and modulates late-age female fecundity

Molecular Genetics and Genomics

Volumn 281, Issue 2, 2009, Pages 147-162

  Li, Yishi ^a   Tower, John ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Aging; Oogenesis; P element; Stem cell; Trade off

Indexed keywords

AGING; ANGIOGENESIS; ARTICLE; CONTROLLED STUDY; DROSOPHILA; FEMALE FERTILITY; GENE; GENE EXPRESSION; GENE MUTATION; HEBE GENE; LIFESPAN; MAGU GENE; NONHUMAN; OOCYTE DEVELOPMENT; PRIORITY JOURNAL; STEM CELL;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; BASE SEQUENCE; BLOTTING, NORTHERN; DNA PRIMERS; DROSOPHILA; DROSOPHILA PROTEINS; FEMALE; FERTILITY; LONGEVITY; MALE; MUTATION;

ANIMALIA; HEBE;

EID: 59449097946     PISSN: 16174615     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00438-008-0400-z     Document Type: Article

References (64)

1. MJ Allikian D Deckert-Cruz MR Rose GN Landis J Tower 2002 Doxycycline-induced expression of sense and inverted-repeat constructs modulates phosphogluconate mutase (Pgm) gene expression in adult Drosophila melanogaster Genome Biol 3 5 research0021
2. AI Barnes JM Boone J Jacobson L Partridge T Chapman 2006 No extension of lifespan by ablation of germ line in Drosophila Proc Biol Sci 273 1589 939 947
3. ET Bieschke JC Wheeler J Tower 1998 Doxycycline-induced transgene expression during Drosophila development and aging Mol Gen Genet 258 6 571 579
4. M Boyle C Wong M Rocha DL Jones 2007 Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testis Cell Stem Cell 1 4 470 478
5. VR Chintapalli J Wang JA Dow 2007 Using FlyAtlas to identify better Drosophila melanogaster models of human disease Nat Genet 39 6 715 720
6. NH Choi JG Kim DJ Yang YS Kim MA Yoo 2008 Age-related changes in Drosophila midgut are associated with PVF2, a PDGF/VEGF-like growth factor Aging Cell 7 3 318 334
7. DJ Clancy D Gems LG Harshman S Oldham H Stocker E Hafen SJ Leevers L Partridge 2001 Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein Science 292 104 106
8. C Curtis GN Landis D Folk NB Wehr N Hoe M Waskar D Abdueva D Skvortsov D Ford A Luu A Badrinath RL Levine TJ Bradley S Tavare J Tower 2007 Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes Genome Biol 8 12 R262
9. A Dillin AL Hsu N Arantes-Oliveira J Lehrer-Graiwer H Hsin AG Fraser RS Kamath J Ahringer C Kenyon 2002 Rates of behavior and aging specified by mitochondrial function during development Science 298 5602 2398 2401
10. D Drummond-Barbosa AC Spradling 2001 Stem cells and their progeny respond to nutritional changes during Drosophila oogenesis Dev Biol 231 1 265 278
11. AC Edwards SM Rollmann TJ Morgan TF Mackay 2006 Quantitative genomics of aggressive behavior in Drosophila melanogaster PLoS Genet 2 9 e154
12. T Flatt TJ Kawecki 2007 Juvenile hormone as a regulator of the trade-off between reproduction and life span in Drosophila melanogaster Evolution 61 8 1980 1991
13. T Flatt KJ Min C D'Alterio E Villa-Cuesta J Cumbers R Lehmann DL Jones M Tatar 2008 Drosophila germ-line modulation of insulin signaling and lifespan Proc Natl Acad Sci USA 105 17 6368 6373
14. D Ford N Hoe GN Landis K Tozer A Luu D Bhole A Badrinath J Tower 2007 Alteration of Drosophila life span using conditional, tissue-specific expression of transgenes triggered by doxycycline or RU486/Mifepristone Exp Gerontol 42 6 483 497
15. MT Fuller AC Spradling 2007 Male and female Drosophila germline stem cells: two versions of immortality Science 316 5823 402 404
16. ME Giannakou M Goss MA Junger E Hafen SJ Leevers L Partridge 2004 Long-lived Drosophila with overexpressed dFOXO in adult fat body Science 305 5682 361
17. ME Giannakou M Goss L Partridge 2008 Role of dFOXO in lifespan extension by dietary restriction in Drosophila melanogaster: not required, but its activity modulates the response Aging Cell 7 2 187 198
18. S Hekimi 2006 How genetic analysis tests theories of animal aging Nat Genet 38 9 985 991
19. G Howlader VK Sharma 2006 Circadian regulation of egg-laying behavior in fruit flies Drosophila melanogaster J Insect Physiol 52 8 779 785
20. HJ Hsu L LaFever D Drummond-Barbosa 2008 Diet controls normal and tumorous germline stem cells via insulin-dependent and -independent mechanisms in Drosophila Dev Biol 313 2 700 712
21. D Hu P Cao E Thiels CT Chu GY Wu TD Oury E Klann 2007 Hippocampal long-term potentiation, memory, and longevity in mice that overexpress mitochondrial superoxide dismutase Neurobiol Learn Mem 87 3 372 384
22. DS Hwangbo B Gersham MP Tu M Palmer M Tatar 2004 Drosophila dFOXO controls lifespan and regulates insulin signalling in brain and fat body Nature 429 6991 562 566
23. TE Johnson PM Tedesco GJ Lithgow 1993 Comparing mutants, selective breeding, and transgenics in the dissection of aging processes of Caenorhabditis elegans Genetica 91 1-3 65 77
24. C Kenyon 2005 The plasticity of aging: insights from long-lived mutants Cell 120 4 449 460
25. C Kenyon J Chang E Gensch A Rudner R Tabtiang 1993 A C. elegans mutant that lives twice as long as wild type Nature 366 6454 461 464
26. A Khokhar N Chen J Yuan Y Li GN Landis G Beaulieu H Kaur J Tower 2008 Conditional switches for extracellular matrix patterning in Drosophila melanogaster Genetics 178 3 1283 1293
27. TB Kirkwood 2005 Understanding the odd science of aging Cell 120 4 437 447
28. L LaFever D Drummond-Barbosa 2005 Direct control of germline stem cell division and cyst growth by neural insulin in Drosophila Science 309 5737 1071 1073
29. G Landis D Bhole L Lu J Tower 2001 High-frequency generation of conditional mutations affecting Drosophila melanogaster development and life span Genetics 158 3 1167 1176
30. GN Landis D Bhole J Tower 2003 A search for doxycycline-dependent mutations that increase Drosophila melanogaster life span identifies the VhaSFD, Sugar baby, filamin, fwd and Cctl genes Genome Biol 4 2 R8
31. W Mair CM Sgro AP Johnson T Chapman L Partridge 2004 Lifespan extension by dietary restriction in female Drosophila melanogaster is not caused by a reduction in vitellogenesis or ovarian activity Exp Gerontol 39 7 1011 1019
32. CA Micchelli N Perrimon 2006 Evidence that stem cells reside in the adult Drosophila midgut epithelium Nature 439 7075 475 479
33. KJ Min R Yamamoto S Buch M Pankratz M Tatar 2008 Drosophila lifespan control by dietary restriction independent of insulin-like signaling Aging Cell 7 2 199 206
34. SJ Morrison AC Spradling 2008 Stem cells and niches: mechanisms that promote stem cell maintenance throughout life Cell 132 4 598 611
35. B Ohlstein A Spradling 2006 The adult Drosophila posterior midgut is maintained by pluripotent stem cells Nature 439 7075 470 474
36. L Pan S Chen C Weng G Call D Zhu H Tang N Zhang T Xie 2007 Stem cell aging is controlled both intrinsically and extrinsically in the Drosophila ovary Cell Stem Cell 1 4 458 469
37. TL Parkes AJ Elia D Dickson AJ Hilliker JP Phillips GL Boulianne 1998 Extension of Drosophila lifespan by overexpression of human SOD1 in motorneurons Nature Genet 19 171 174
38. Partridge L, Tower J (2008) Yeast, a feast: the fruit fly Drosophila as a model organism for research into aging. In: Guarente LP, Partridge L, Wallace DC (eds) Molecular biology of aging. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, pp 267-308
39. L Partridge D Gems DJ Withers 2005 Sex and death: what is the connection? Cell 120 4 461 472
40. JS Patton XV Gomes PK Geyer 1992 Position-independent germline transformation in Drosophila using a cuticle pigmentation gene as a selectable marker Nucleic Acids Res 20 5859 5860
41. MD Piper L Partridge 2007 Dietary restriction in Drosophila: delayed aging or experimental artefact? PLoS Genet 3 4 e57
42. MJ Reed JM Edelberg 2004 Impaired angiogenesis in the aged Sci Aging Knowledge Environ 2004 7 pe7
43. C Ren P Webster SE Finkel J Tower 2007 Increased internal and external bacterial load during Drosophila aging without life-span trade-off Cell Metab 6 2 144 152
44. EF Rocnik P Liu K Sato K Walsh C Vaziri 2006 The novel SPARC family member SMOC-2 potentiates angiogenic growth factor activity J Biol Chem 281 32 22855 22864
45. GM Rubin AC Spradling 1982 Genetic transformation of Drosophila with transposable element vectors Science 218 348 353
46. C Selman S Lingard AI Choudhury RL Batterham M Claret M Clements F Ramadani K Okkenhaug E Schuster E Blanc MD Piper H Al-Qassab JR Speakman D Carmignac IC Robinson JM Thornton D Gems L Partridge DJ Withers 2008 Evidence for lifespan extension and delayed age-related biomarkers in insulin receptor substrate 1 null mice Faseb J 22 3 807 818
47. CM Sgro L Partridge 1999 A delayed wave of death from reproduction in Drosophila Science 286 5449 2521 2524
48. SR Singh W Liu SX Hou 2007 The adult Drosophila malpighian tubules are maintained by multipotent stem cells Cell Stem Cell 1 191 203
49. CC Spencer CE Howell AR Wright DE Promislow 2003 Testing an 'aging gene' in long-lived drosophila strains: increased longevity depends on sex and genetic background Aging Cell 2 2 123 130
50. MJ Stebbins S Urlinger G Byrne B Bello W Hillen JC Yin 2001 Tetracycline-inducible systems for Drosophila Proc Natl Acad Sci USA 98 19 10775 10780
51. J Sun J Tower 1999 FLP recombinase-mediated induction of Cu/Zn-superoxide dismutase transgene expression can extend the life span of adult Drosophila melanogaster flies Mol Cell Biol 19 1 216 228
52. J Sun D Folk TJ Bradley J Tower 2002 Induced overexpression of mitochondrial Mn-superoxide dismutase extends the life span of adult Drosophila melanogaster Genetics 161 2 661 672
53. J Sun J Molitor J Tower 2004 Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span Mech Ageing Dev 125 5 341 349
54. M Tatar A Kopelman D Epstein MP Tu CM Yin RS Garofalo 2001 A mutant Drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function Science 292 5514 107 110
55. NA Terry N Tulina E Matunis S DiNardo 2006 Novel regulators revealed by profiling Drosophila testis stem cells within their niche Dev Biol 294 1 246 257
56. Toivonen JM, Partridge L (2008) Endocrine regulation of ageing and reproduction in Drosophila. Mol Cell Endocrinol. doi: 10.1016/j.mce.2008.07.005
57. J Tower 2000 Transgenic methods for increasing Drosophila life span Mech Ageing Dev 118 1-2 1 14
58. C Vannahme S Gosling M Paulsson P Maurer U Hartmann 2003 Characterization of SMOC-2, a modular extracellular calcium-binding protein Biochem J 373 Pt 3 805 814
59. MR Wallenfang R Nayak S DiNardo 2006 Dynamics of the male germline stem cell population during aging of Drosophila melanogaster Aging Cell 5 4 297 304
60. M Waskar Y Li J Tower 2005 Stem Cell Aging in the Drosophila Ovary Age 27 201 212
61. GC Williams 1966 Natural selection, the costs of reproduction, and a refinement of Lack's principle Amer Natur 100 687 690
62. S Wolff A Dillin 2006 The trifecta of aging in Caenorhabditis elegans Exp Gerontol 41 10 894 903
63. TM Yamawaki N Arantes-Oliveira JR Berman P Zhang C Kenyon 2008 Distinct activities of the germline and somatic reproductive tissues in the regulation of Caenorhabditis elegans' longevity Genetics 178 1 513 526
64. R Zhao Y Xuan X Li R Xi 2008 Age-related changes of germline stem cell activity, niche signaling activity and egg production in Drosophila Aging Cell 7 3 344 354