메뉴 건너뛰기




Volumn 181, Issue 9, 2008, Pages 5912-5929

Fas expression on antigen-specific T cells has costimulatory, helper, and down-regulatory functions in vivo for cytotoxic T cell responses but not for T cell-dependent B cell responses

Author keywords

[No Author keywords available]

Indexed keywords

FAS ANTIGEN; EPITOPE;

EID: 58749096040     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.9.5912     Document Type: Article
Times cited : (25)

References (102)
  • 1
    • 5644241900 scopus 로고    scopus 로고
    • T-lymphocyte death during shutdown of an immune response
    • DOI 10.1016/j.it.2004.08.012, PII S1471490604002649
    • Strasser, A., and M. Pellegrini. 2004. T-lymphocyte death during shutdown of an immune response. Trends Immunol. 25: 610-615. (Pubitemid 39369738)
    • (2004) Trends in Immunology , vol.25 , Issue.11 , pp. 610-615
    • Strasser, A.1    Pellegrini, M.2
  • 3
    • 0038171458 scopus 로고    scopus 로고
    • Activation-induced cell death in T cells
    • Green, D. R., N. Droin, and M. Pinkoski. 2003. Activation-induced cell death in T cells. Immunol. Rev. 193: 70-81.
    • (2003) Immunol. Rev. , vol.193 , pp. 70-81
    • Green, D.R.1    Droin, N.2    Pinkoski, M.3
  • 4
    • 0034641898 scopus 로고    scopus 로고
    • CD95's deadly mission in the immune system
    • Krammer, P. H. 2000. CD95's deadly mission in the immune system. Nature 407: 789-795.
    • (2000) Nature , vol.407 , pp. 789-795
    • Krammer, P.H.1
  • 5
    • 0037833695 scopus 로고    scopus 로고
    • The role of CD95 in the regulation of peripheral T-cell apoptosis
    • DOI 10.1034/j.1600-065X.2003.00047.x
    • Krueger, A., S. C. Fas, S. Baumann, and P. H. Krammer. 2003. The role of CD95 in the regulation of peripheral T-cell apoptosis. Immunol. Rev. 193: 58-69. (Pubitemid 36688040)
    • (2003) Immunological Reviews , vol.193 , pp. 58-69
    • Krueger, A.1    Fas, S.C.2    Baumann, S.3    Krammer, P.H.4
  • 7
    • 0032005484 scopus 로고    scopus 로고
    • The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens
    • DOI 10.1016/S1074-7613(00)80478-1
    • Van Parijs, L., D. A. Peterson, and A. K. Abbas. 1998. The Fas/Fas ligand pathway and Bcl-2 regulate T cell responses to model self and foreign antigens. Immunity 8: 265-274. (Pubitemid 28123753)
    • (1998) Immunity , vol.8 , Issue.2 , pp. 265-274
    • Van Parijs, L.1    Peterson, D.A.2    Abbas, A.K.3
  • 8
    • 0032031457 scopus 로고    scopus 로고
    • Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes
    • Van Parijs, L., A. Biuckians, and A. K. Abbas. 1998. Functional roles of Fas and Bcl-2-regulated apoptosis of T lymphocytes. J. Immunol. 160: 2065-2071.
    • (1998) J. Immunol. , vol.160 , pp. 2065-2071
    • Van Parijs, L.1    Biuckians, A.2    Abbas, A.K.3
  • 10
    • 0033607506 scopus 로고    scopus 로고
    • Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity
    • Bouillet, P., D. Metcalf, D. C. Huang, D. M. Tarlinton, T. W. Kay, F. Kontgen, J. M. Adams, and A. Strasser. 1999. Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity. Science 286: 1735-1738. (Pubitemid 129515880)
    • (1999) Science , vol.286 , Issue.5445 , pp. 1735-1738
    • Bouillet, P.1    Metcalf, D.2    Huang, D.C.S.3    Tarlinton, D.M.4    Kay, T.W.H.5    Kontgen, F.6    Adams, J.M.7    Strasser, A.8
  • 12
    • 0033555391 scopus 로고    scopus 로고
    • A role for perforin in activation-induced T cell death in vivo: Increased expansion of allogeneic perforin-deficient T cells in SCID mice
    • Spaner, D., K. Raju, B. Rabinovich, and R. G. Miller. 1999. A role for perforin in activation-induced T cell death in vivo: increased expansion of allogeneic perforin-deficient T cells in SCID mice. J. Immunol. 162: 1192-1199. (Pubitemid 29035453)
    • (1999) Journal of Immunology , vol.162 , Issue.2 , pp. 1192-1199
    • Spaner, D.1    Raju, K.2    Rabinovich, B.3    Miller, R.G.4
  • 13
    • 0033151622 scopus 로고    scopus 로고
    • Reactive oxygen species regulate activation-induced T cell apoptosis
    • DOI 10.1016/S1074-7613(00)80072-2
    • Hildeman, D. A., T. Mitchell, T. K. Teague, P. Henson, B. J. Day, J. Kappler, and P. C. Marrack. 1999. Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity 10: 735-744. (Pubitemid 29302926)
    • (1999) Immunity , vol.10 , Issue.6 , pp. 735-744
    • Hildeman, D.A.1    Mitchell, T.2    Teague, T.K.3    Henson, P.4    Day, B.J.5    Kappler, J.6    Marrack, P.C.7
  • 14
    • 0030845413 scopus 로고    scopus 로고
    • Pathways leading to cell death in T cells
    • DOI 10.1016/S0952-7915(97)80082-9
    • Wong, B., and Y. Choi. 1997. Pathways leading to cell death in T cells. Curr. Opin. Immunol. 9: 358-364. (Pubitemid 27303505)
    • (1997) Current Opinion in Immunology , vol.9 , Issue.3 , pp. 358-364
    • Wong, B.1    Choi, Y.2
  • 16
    • 0026568919 scopus 로고
    • Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis
    • Watanabe-Fukunaga, R., C. I. Brannan, N. G. Copeland, N. A. Jenkins, and S. Nagata. 1992. Lymphoproliferation disorder in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356: 314-317.
    • (1992) Nature , vol.356 , pp. 314-317
    • Watanabe-Fukunaga, R.1    Brannan, C.I.2    Copeland, N.G.3    Jenkins, N.A.4    Nagata, S.5
  • 17
    • 0028223847 scopus 로고
    • Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
    • DOI 10.1016/0092-8674(94)90375-1
    • Takahashi, T., M. Tanaka, C. I. Brannan, N. A. Jenkins, N. G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76: 969-976. (Pubitemid 24106378)
    • (1994) Cell , vol.76 , Issue.6 , pp. 969-976
    • Takahashi, T.1    Tanaka, M.2    Brannan, C.I.3    Jenkins, N.A.4    Copeland, N.G.5    Suda, T.6    Nagata, S.7
  • 20
    • 20444438369 scopus 로고    scopus 로고
    • Paths to understanding the genetic basis of autoimmune disease
    • DOI 10.1038/nature03723
    • Rioux, J. D., and A. K. Abbas. 2005. Paths to understanding the genetic basis of autoimmune disease. Nature 435: 584-589. (Pubitemid 40825497)
    • (2005) Nature , vol.435 , Issue.7042 , pp. 584-589
    • Rioux, J.D.1    Abbas, A.K.2
  • 21
    • 0025875259 scopus 로고
    • lpr and gld: Single gene models of systemic autoimmunity and lymphoproliferative disease
    • Cohen, P. L., and R. A. Eisenberg. 1991. lpr and gld: single gene models of systemic autoimmunity and lymphoproliferative disease. Annu. Rev. Immunol. 9: 243-269.
    • (1991) Annu. Rev. Immunol. , vol.9 , pp. 243-269
    • Cohen, P.L.1    Eisenberg, R.A.2
  • 22
    • 0021288692 scopus 로고
    • The influence of the lpr gene on B cell activation: Differential antibody expression in lpr congenic mouse strains
    • Warren, R. W., S. A. Caster, J. B. Roths, E. D. Murphy, and D. S. Pisetsky. 1984. The influence of the lpr gene on B cell activation: differential antibody expression in lpr congenic mouse strains. Clin. Immunol. Immunopathol. 31: 65-77.
    • (1984) Clin. Immunol. Immunopathol. , vol.31 , pp. 65-77
    • Warren, R.W.1    Caster, S.A.2    Roths, J.B.3    Murphy, E.D.4    Pisetsky, D.S.5
  • 23
    • 0027477318 scopus 로고
    • Nucleosome: A major immunogen for pathogenic autoantibody-inducing T cells of lupus
    • Mohan, C., S. Adams, V. Stanik, and S. K. Datta. 1993. Nucleosome: a major immunogen for pathogenic autoantibody-inducing T cells of lupus. J. Exp. Med. 177: 1367-1381. (Pubitemid 23117127)
    • (1993) Journal of Experimental Medicine , vol.177 , Issue.5 , pp. 1367-1381
    • Mohan, C.1    Adams, S.2    Stanik, V.3    Datta, S.K.4
  • 24
    • 0032493059 scopus 로고    scopus 로고
    • Antibodies to DNA
    • Hahn, B. H. 1998. Antibodies to DNA. N. Engl. J. Med. 338: 1359-1368.
    • (1998) N. Engl. J. Med. , vol.338 , pp. 1359-1368
    • Hahn, B.H.1
  • 26
    • 0032841840 scopus 로고    scopus 로고
    • Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice
    • DOI 10.1084/jem.190.5.639
    • Wang, H., and M. J. Shlomchik. 1999. Autoantigen-specific B cell activation in Fas-deficient rheumatoid factor immunoglobulin transgenic mice. J. Exp. Med. 190: 639-649. (Pubitemid 29428648)
    • (1999) Journal of Experimental Medicine , vol.190 , Issue.5 , pp. 639-649
    • Wang, H.1    Shlomchik, M.J.2
  • 27
    • 0028789148 scopus 로고
    • Anatomy of autoantibody production: Dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice
    • Jacobson, B. A., D. J. Panka, K. A. Nguyen, J. Erikson, A. K. Abbas, and A. Marshak-Rothstein. 1995. Anatomy of autoantibody production: dominant localization of antibody-producing cells to T cell zones in Fas-deficient mice. Immunity 3: 509-519.
    • (1995) Immunity , vol.3 , pp. 509-519
    • Jacobson, B.A.1    Panka, D.J.2    Nguyen, K.A.3    Erikson, J.4    Abbas, A.K.5    Marshak-Rothstein, A.6
  • 28
    • 0029416937 scopus 로고
    • Expression of Fas in B cells of the mouse germinal center and Fas-dependent killing of activated B cells
    • Watanabe, D., T. Suda, and S. Nagata. 1995. Expression of Fas in B cells of the mouse germinal center and Fas-dependent killing of activated B cells. Int. Immunol. 7: 1949-1956. (Pubitemid 3007594)
    • (1995) International Immunology , vol.7 , Issue.12 , pp. 1949-1956
    • Watanabe, D.1    Suda, T.2    Nagata, S.3
  • 30
    • 0023952393 scopus 로고
    • The lpr gene causes an intrinsic T cell abnormality that is required for hyperproliferation
    • Katagiri, T., P. L. Cohen, and R. A. Eisenberg. 1988. The lpr gene causes an intrinsic T cell abnormality that is required for hyperproliferation. J. Exp. Med. 167: 741-751. (Pubitemid 18111395)
    • (1988) Journal of Experimental Medicine , vol.167 , Issue.3 , pp. 741-751
    • Katagiri, T.1    Cohen, P.L.2    Eisenberg, R.A.3
  • 32
    • 0029862164 scopus 로고    scopus 로고
    • Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes
    • Koshy, M., D. Berger, and M. K. Crow. 1996. Increased expression of CD40 ligand on systemic lupus erythematosus lymphocytes. J. Clin. Invest. 98: 826-837. (Pubitemid 26349188)
    • (1996) Journal of Clinical Investigation , vol.98 , Issue.3 , pp. 826-837
    • Koshy, M.1    Berger, D.2    Crow, M.K.3
  • 33
    • 0027231554 scopus 로고
    • lpr T cells are necessary for autoantibody production in lpr mice
    • Sobel, E. S., P. L. Cohen, and R. A. Eisenberg. 1993. lpr T cells are necessary for autoantibody production in lpr mice. J. Immunol. 150: 4160-4167.
    • (1993) J. Immunol. , vol.150 , pp. 4160-4167
    • Sobel, E.S.1    Cohen, P.L.2    Eisenberg, R.A.3
  • 34
  • 35
    • 0030589227 scopus 로고    scopus 로고
    • Induction of nonpathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic αβ T cell: Separation of autoantigen-s pecific and -nonspecific help
    • Peng, S. L., S. Fatenejad, and J. Craft. 1996. Induction of nonpathologic, humoral autoimmunity in lupus-prone mice by a class II-restricted, transgenic αβ T cell: separation of autoantigen-specific and -nonspecific help. J. Immunol. 157: 5225-5230.
    • (1996) J. Immunol. , vol.157 , pp. 5225-5230
    • Peng, S.L.1    Fatenejad, S.2    Craft, J.3
  • 37
    • 0035525528 scopus 로고    scopus 로고
    • From T to B and back again: Positive feedback in systemic autoimmune disease
    • Shlomchik, M. J., J. E. Craft, and M. J. Mamula. 2001. From T to B and back again: positive feedback in systemic autoimmune disease. Nat. Rev. Immunol 1: 147-153.
    • (2001) Nat. Rev. Immunol , vol.1 , pp. 147-153
    • Shlomchik, M.J.1    Craft, J.E.2    Mamula, M.J.3
  • 38
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
    • DOI 10.1146/annurev.immunol.17.1.221
    • Lenardo, M., K. M. Chan, F. Hornung, H. McFarland, R. Siegel, J. Wang, and L. Zheng. 1999. Mature T lymphocyte apoptosis-immune regulation in a dynamic and unpredictable antigenic environment. Annu. Rev. Immunol. 17: 221-253. (Pubitemid 29241124)
    • (1999) Annual Review of Immunology , vol.17 , pp. 221-253
    • Lenardo, M.1    Chan, F.K.-M.2    Hornung, F.3    McFarland, H.4    Siegel, R.5    Wang, J.6    Zheng, L.7
  • 39
    • 19244387337 scopus 로고    scopus 로고
    • Differential TCR signaling regulates apoptosis and immunopathology during antigen responses in vivo
    • Combadiere, B., C. Reis e Sousa, C. Trageser, L. X. Zheng, C. R. Kim, and M. J. Lenardo. 1998. Differential TCR signaling regulates apoptosis and immunopathology during antigen responses in vivo. Immunity 9: 305-313.
    • (1998) Immunity , vol.9 , pp. 305-313
    • Combadiere, B.1    Reis E Sousa, C.2    Trageser, C.3    Zheng, L.X.4    Kim, C.R.5    Lenardo, M.J.6
  • 40
    • 0031572509 scopus 로고    scopus 로고
    • Maintenance of Clonotype Specificity in CD95/Apo-1/ Fas-Mediated Apoptosis of Mature T Lymphocytes
    • Hornung, F., L. Zheng, and M. J. Lenardo. 1997. Maintenance of clonotype specificity in CD95/Apo-1/Fas-mediated apoptosis of mature T lymphocytes. J. Immunol. 159: 3816-3822. (Pubitemid 127469637)
    • (1997) Journal of Immunology , vol.159 , Issue.8 , pp. 3816-3822
    • Hornung, F.1    Zheng, L.2    Lenardo, M.J.3
  • 41
    • 2542449195 scopus 로고    scopus 로고
    • T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis
    • DOI 10.1084/jem.20032196
    • Hao, Z., B. Hampel, H. Yagita, and K. Rajewsky. 2004. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis. J. Exp. Med. 199: 1355-1365. (Pubitemid 38685727)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.10 , pp. 1355-1365
    • Hao, Z.1    Hampel, B.2    Yagita, H.3    Rajewsky, K.4
  • 43
    • 0023879179 scopus 로고
    • T-cell interactions in autoimmunity: Insights from a murine model of graft-versus-host disease
    • Via, C. S., and G. M. Shearer. 1988. T-cell interactions in autoimmunity: insights from a murine model of graft-versus-host disease. Immunol. Today 9: 207-213. (Pubitemid 18166204)
    • (1988) Immunology Today , vol.9 , Issue.7-8 , pp. 207-213
    • Via, C.S.1    Shearer, G.M.2
  • 44
    • 0020082244 scopus 로고
    • A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation: Preferential formation of autoantibodies characteristic of SLE
    • Gleichmann, E., E. H. Van Elven, and J. P. Van der Veen. 1982. A systemic lupus erythematosus (SLE)-like disease in mice induced by abnormal T-B cell cooperation: preferential formation of autoantibodies characteristic of SLE. Eur. J. Immunol. 12: 152-159.
    • (1982) Eur. J. Immunol. , vol.12 , pp. 152-159
    • Gleichmann, E.1    Van Elven, E.H.2    Van Der Veen, J.P.3
  • 45
    • 0025138736 scopus 로고
    • Autoantibodies in chronic graft versus host result from cognate T-B interactions
    • Morris, S. C., R. L. Cheek, P. L. Cohen, and R. A. Eisenberg. 1990. Autoantibodies in chronic graft versus host result from cognate T-B interactions. J. Exp. Med. 171: 503-517.
    • (1990) J. Exp. Med. , vol.171 , pp. 503-517
    • Morris, S.C.1    Cheek, R.L.2    Cohen, P.L.3    Eisenberg, R.A.4
  • 46
    • 1842870735 scopus 로고    scopus 로고
    • The chronic graft-versus-host model of systemic autoimmunity
    • Eisenberg, R. 2003. The chronic graft-versus-host model of systemic autoimmunity. Curr. Dir. Autoimmun. 6: 228-244.
    • (2003) Curr. Dir. Autoimmun. , vol.6 , pp. 228-244
    • Eisenberg, R.1
  • 48
    • 13844316916 scopus 로고    scopus 로고
    • Measurement of daughter cell accumulation during lymphocyte proliferation in vivo
    • Thompson, B. S., and T. C. Mitchell. 2004. Measurement of daughter cell accumulation during lymphocyte proliferation in vivo. J. Immunol. Methods 295: 79-87.
    • (2004) J. Immunol. Methods , vol.295 , pp. 79-87
    • Thompson, B.S.1    Mitchell, T.C.2
  • 51
    • 3142734334 scopus 로고    scopus 로고
    • Differential requirement for IFN-γ in CTL maturation in acute murine graft-versus-host disease
    • Puliaev, R., P. Nguyen, F. D. Finkelman, and C. S. Via. 2004. Differential requirement for IFN-γ in CTL maturation in acute murine graft-versus-host disease. J. Immunol. 173: 910-919. (Pubitemid 38924264)
    • (2004) Journal of Immunology , vol.173 , Issue.2 , pp. 910-919
    • Puliaev, R.1    Nguyen, P.2    Finkelman, F.D.3    Via, C.S.4
  • 53
    • 0024215452 scopus 로고
    • Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis
    • Passwell, J., G. F. Schreiner, M. Nonaka, H. U. Beuscher, and H. R. Colten. 1988. Local extrahepatic expression of complement genes C3, factor B, C2, and C4 is increased in murine lupus nephritis. J. Clin. Invest. 82: 1676-1684. (Pubitemid 19007773)
    • (1988) Journal of Clinical Investigation , vol.82 , Issue.5 , pp. 1676-1684
    • Passwell, J.1    Schreiner, G.F.2    Nonaka, M.3    Beuscher, H.U.4    Colten, H.R.5
  • 54
    • 0029909099 scopus 로고    scopus 로고
    • An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin
    • Cooke, K. R., L. Kobzik, T. R. Martin, J. Brewer, J. Delmonte, Jr., J. M. Crawford, and J. L. Ferrara. 1996. An experimental model of idiopathic pneumonia syndrome after bone marrow transplantation: I. The roles of minor H antigens and endotoxin. Blood 88: 3230-3239.
    • (1996) Blood , vol.88 , pp. 3230-3239
    • Cooke, K.R.1    Kobzik, L.2    Martin, T.R.3    Brewer, J.4    Delmonte Jr., J.5    Crawford, J.M.6    Ferrara, J.L.7
  • 55
    • 0023266683 scopus 로고
    • Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease
    • Via, C. S., S. O. Sharrow, and G. M. Shearer. 1987. Role of cytotoxic T lymphocytes in the prevention of lupus-like disease occurring in a murine model of graft-vs-host disease. J. Immunol. 139: 1840-1849.
    • (1987) J. Immunol. , vol.139 , pp. 1840-1849
    • Via, C.S.1    Sharrow, S.O.2    Shearer, G.M.3
  • 56
    • 0026515438 scopus 로고
    • Protection from lethal graft-vs.-host disease by donor stem cell repopulation
    • Rozendaal, L., S. T. Pals, C. J. Melief, and E. Gleichmann. 1992. Protection from lethal graft-vs.-host disease by donor stem cell repopulation. Eur. J. Immunol. 22: 575-579.
    • (1992) Eur. J. Immunol. , vol.22 , pp. 575-579
    • Rozendaal, L.1    Pals, S.T.2    Melief, C.J.3    Gleichmann, E.4
  • 57
    • 24344481264 scopus 로고    scopus 로고
    • Both apoptosis and complement membrane attack complex deposition are major features of murine acute graft-vs.-host disease
    • DOI 10.1016/j.yexmp.2005.03.007, PII S0014480005000626
    • Niculescu, F., T. Niculescu, P. Nguyen, R. Puliaev, J. C. Papadimitriou, A. Gaspari, H. Rus, and C. S. Via. 2005. Both apoptosis and complement membrane attack complex deposition are major features of murine acute graft-vs.-host disease. Exp. Mol. Pathol. 79: 136-145. (Pubitemid 41262495)
    • (2005) Experimental and Molecular Pathology , vol.79 , Issue.2 , pp. 136-145
    • Niculescu, F.1    Niculescu, T.2    Nguyen, P.3    Puliaev, R.4    Papadimitriou, J.C.5    Gaspari, A.6    Rus, H.7    Via, C.S.8
  • 61
    • 0020589503 scopus 로고
    • Allosuppressor- and allohelper-T cells in acute and chronic graft-vs.-host (GVH) disease: III. Different Lyt subsets of donor T cells induce different pathological syndromes
    • Rolink, A. G., and E. Gleichmann. 1983. Allosuppressor- and allohelper-T cells in acute and chronic graft-vs.-host (GVH) disease: III. Different Lyt subsets of donor T cells induce different pathological syndromes. J. Exp. Med. 158: 546-558.
    • (1983) J. Exp. Med. , vol.158 , pp. 546-558
    • Rolink, A.G.1    Gleichmann, E.2
  • 64
    • 0023127296 scopus 로고
    • Anti-receptor anti-MHC cytotoxic T lymphocytes: Their role in the resistance to graft vs host reaction
    • Kosmatopoulos, K., D. S. Algara, and S. Orbach-Arbouys. 1987. Anti-receptor anti-MHC cytotoxic T lymphocytes: their role in the resistance to graft vs host reaction. J. Immunol. 138: 1038-1041. (Pubitemid 17017881)
    • (1987) Journal of Immunology , vol.138 , Issue.4 , pp. 1038-1041
    • Kosmatopoulos, K.1    Algara, D.S.2    Orbach-Arbouys, S.3
  • 65
    • 47949123740 scopus 로고    scopus 로고
    • CTL-promoting effects of CD40 stimulation outweigh B cell-stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus
    • Puliaev, R., I. Puliaeva, L. A. Welniak, A. E. Ryan, M. Haas, W. J. Murphy, and C. S. Via. 2008. CTL-promoting effects of CD40 stimulation outweigh B cell-stimulatory effects resulting in B cell elimination and disease improvement in a murine model of lupus. J. Immunol. 181: 47-61.
    • (2008) J. Immunol. , vol.181 , pp. 47-61
    • Puliaev, R.1    Puliaeva, I.2    Welniak, L.A.3    Ryan, A.E.4    Haas, M.5    Murphy, W.J.6    Via, C.S.7
  • 66
    • 17144450359 scopus 로고    scopus 로고
    • + T cells by perforin
    • DOI 10.1002/(SICI)1521-4141(199910)29:10<3262::AID-IMMU3262>3.0. CO;2-A
    • Kagi, D., B. Odermatt, and T. W. Mak. 1999. Homeostatic regulation of CD8+ T cells by perforin. Eur. J. Immunol. 29: 3262-3272. (Pubitemid 29484217)
    • (1999) European Journal of Immunology , vol.29 , Issue.10 , pp. 3262-3272
    • Kagi, D.1    Odermatt, B.2    Mak, T.W.3
  • 67
    • 0035479955 scopus 로고    scopus 로고
    • The role of cytotoxicity in lymphocyte homeostasis
    • De Saint Basile, G., and A. Fischer. 2001. The role of cytotoxicity in lymphocyte homeostasis. Curr. Opin. Immunol. 13: 549-554.
    • (2001) Curr. Opin. Immunol. , vol.13 , pp. 549-554
    • De Saint Basile, G.1    Fischer, A.2
  • 69
    • 34447646310 scopus 로고    scopus 로고
    • Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses
    • Butte, M. J., M. E. Keir, T. B. Phamduy, A. H. Sharpe, and G. J. Freeman. 2007. Programmed death-1 ligand 1 interacts specifically with the B7-1 costimulatory molecule to inhibit T cell responses. Immunity 27: 111-122.
    • (2007) Immunity , vol.27 , pp. 111-122
    • Butte, M.J.1    Keir, M.E.2    Phamduy, T.B.3    Sharpe, A.H.4    Freeman, G.J.5
  • 70
    • 0025729604 scopus 로고
    • An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity
    • Sobel, E. S., T. Katagiri, K. Katagiri, S. C. Morris, P. L. Cohen, and R. A. Eisenberg. 1991. An intrinsic B cell defect is required for the production of autoantibodies in the lpr model of murine systemic autoimmunity. J. Exp. Med. 173: 1441-1449.
    • (1991) J. Exp. Med. , vol.173 , pp. 1441-1449
    • Sobel, E.S.1    Katagiri, T.2    Katagiri, K.3    Morris, S.C.4    Cohen, P.L.5    Eisenberg, R.A.6
  • 71
    • 33646442250 scopus 로고    scopus 로고
    • Fas costimulation of naive CD4 T cells is controlled by NF-κB signaling and caspase activity
    • DOI 10.1189/jlb.0505238
    • Maksimow, M., T. S. Soderstrom, S. Jalkanen, J. E. Eriksson, and A. Hanninen. 2006. Fas costimulation of naive CD4 T cells is controlled by NF-κB signaling and caspase activity. J. Leukocyte Biol. 79: 369-377. (Pubitemid 44831169)
    • (2006) Journal of Leukocyte Biology , vol.79 , Issue.2 , pp. 369-377
    • Maksimow, M.1    Soderstrom, T.S.2    Jalkanen, S.3    Eriksson, J.E.4    Hanninen, A.5
  • 73
    • 0033386808 scopus 로고    scopus 로고
    • Caspase activation is required for T cell proliferation
    • Kennedy, N. J., T. Kataoka, J. Tschopp, and R. C. Budd. 1999. Caspase activation is required for T cell proliferation. J. Exp. Med. 190: 1891-1896.
    • (1999) J. Exp. Med. , vol.190 , pp. 1891-1896
    • Kennedy, N.J.1    Kataoka, T.2    Tschopp, J.3    Budd, R.C.4
  • 74
    • 0029939945 scopus 로고    scopus 로고
    • The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance
    • DOI 10.1016/S1074-7613(00)80440-9
    • Van Parijs, L., A. Ibraghimov, and A. K. Abbas. 1996. The roles of costimulation and Fas in T cell apoptosis and peripheral tolerance. Immunity 4: 321-328. (Pubitemid 126349699)
    • (1996) Immunity , vol.4 , Issue.3 , pp. 321-328
    • Van Parijs, L.1    Ibraghimov, A.2    Abbas, A.K.3
  • 75
    • 0037037582 scopus 로고    scopus 로고
    • Interferon γ is required for activation-induced death of T lymphocytes
    • Refaeli, Y., L. Van Parijs, S. I. Alexander, and A. K. Abbas. 2002. Interferon γ is required for activation-induced death of T lymphocytes. J. Exp. Med. 196: 999-1005.
    • (2002) J. Exp. Med. , vol.196 , pp. 999-1005
    • Refaeli, Y.1    Van Parijs, L.2    Alexander, S.I.3    Abbas, A.K.4
  • 76
    • 0022357754 scopus 로고
    • Pathogenesis of graft-versus-host reactions (GVHR) and GVH-like diseases
    • Gleichmann, E., and H. Gleichmann. 1985. Pathogenesis of graft-versus-host reactions (GVHR) and GVH-like diseases. J. Invest. Dermatol. 85: 115s-120s. (Pubitemid 16235464)
    • (1985) Journal of Investigative Dermatology , vol.85 , Issue.SUPPL. 1
    • Gleichmann, E.1    Gleichmann, H.2
  • 77
    • 0035892750 scopus 로고    scopus 로고
    • In vivo neutralization of TNF-α promotes humoral autoimmunity by preventing the induction of CTL
    • Via, C. S., A. Shustov, V. Rus, T. Lang, P. Nguyen, and F. D. Finkelman. 2001. In vivo neutralization of TNF-α promotes humoral autoimmunity by preventing the induction of CTL. J. Immunol. 167: 6821-6826.
    • (2001) J. Immunol. , vol.167 , pp. 6821-6826
    • Via, C.S.1    Shustov, A.2    Rus, V.3    Lang, T.4    Nguyen, P.5    Finkelman, F.D.6
  • 78
    • 0027323622 scopus 로고
    • Critical role of interleukin-2 in the development of acute graft-versus-host disease
    • Via, C. S., and F. D. Finkelman. 1993. Critical role of interleukin-2 in the development of acute graft-versus-host disease. Int. Immunol. 5: 565-572. (Pubitemid 23209409)
    • (1993) International Immunology , vol.5 , Issue.6 , pp. 565-572
    • Via, C.S.1    Finkelman, F.D.2
  • 79
    • 0027971672 scopus 로고
    • IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would develop chronic, autoimmune graft-versus-host disease
    • Via, C. S., V. Rus, M. K. Gately, and F. D. Finkelman. 1994. IL-12 stimulates the development of acute graft-versus-host disease in mice that normally would develop chronic, autoimmune graft-versus-host disease. J. Immunol. 153: 4040-4047.
    • (1994) J. Immunol. , vol.153 , pp. 4040-4047
    • Via, C.S.1    Rus, V.2    Gately, M.K.3    Finkelman, F.D.4
  • 80
    • 0030589301 scopus 로고    scopus 로고
    • A major role for the Fas pathway in acute graft-versus-host disease
    • Via, C. S., P. Nguyen, A. Shustov, J. Drappa, and K. B. Elkon. 1996. A major role for the Fas pathway in acute graft-versus-host disease. J. Immunol. 157: 5387-5393.
    • (1996) J. Immunol. , vol.157 , pp. 5387-5393
    • Via, C.S.1    Nguyen, P.2    Shustov, A.3    Drappa, J.4    Elkon, K.B.5
  • 82
    • 0031973637 scopus 로고    scopus 로고
    • Maximal proliferation of cytotoxic T lymphocytes requires reverse signaling through Fas ligand
    • DOI 10.1084/jem.187.1.123
    • Suzuki, I., and P. J. Fink. 1998. Maximal proliferation of cytotoxic T lymphocytes requires reverse signaling through Fas ligand. J. Exp. Med. 187: 123-128. (Pubitemid 28044827)
    • (1998) Journal of Experimental Medicine , vol.187 , Issue.1 , pp. 123-128
    • Suzuki, I.1    Fink, P.J.2
  • 85
    • 0242566879 scopus 로고    scopus 로고
    • Reactivation of systemic lupus erythematosus after initiation of highly active antiretroviral therapy for acquired immunodeficiency syndrome
    • Drake, W. P., V. M. Byrd, and N. J. Olsen. 2003. Reactivation of systemic lupus erythematosus after initiation of highly active antiretroviral therapy for acquired immunodeficiency syndrome. J. Clin. Rheumatol. 9: 176-180.
    • (2003) J. Clin. Rheumatol. , vol.9 , pp. 176-180
    • Drake, W.P.1    Byrd, V.M.2    Olsen, N.J.3
  • 86
    • 0021965670 scopus 로고
    • 1 mice with monoclonal antibody to L3T4
    • 1 mice with monoclonal antibody to L3T4. J. Exp. Med. 161: 378-391.
    • (1985) J. Exp. Med. , vol.161 , pp. 378-391
    • Wofsy, D.1    Seaman, W.E.2
  • 87
    • 0022570604 scopus 로고
    • Administration of monoclonal anti-T cell antibodies retards murine lupus in BXSB mice
    • Wofsy, D. 1986. Administration of monoclonal anti-T cell antibodies retards murine lupus in BXSB mice. J. Immunol. 136: 4554-4560. (Pubitemid 16090676)
    • (1986) Journal of Immunology , vol.136 , Issue.12 , pp. 4554-4560
    • Wofsy, D.1
  • 88
    • 0035808778 scopus 로고    scopus 로고
    • + T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: A model to explain spontaneous T cell activation in lupus
    • + T cells from lupus-prone mice are hyperresponsive to T cell receptor engagement with low and high affinity peptide antigens: a model to explain spontaneous T cell activation in lupus. J. Exp. Med. 193: 329-337.
    • (2001) J. Exp. Med. , vol.193 , pp. 329-337
    • Vratsanos, G.S.1    Jung, S.2    Park, Y.M.3    Craft, J.4
  • 89
    • 17044393073 scopus 로고    scopus 로고
    • + T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyperproliferation due to intrinsic threshold defects in activation
    • + T cells from lupus-prone Fas-intact MRL mice display TCR-mediated hyperproliferation due to intrinsic threshold defects in activation. J. Immunol. 174: 5100-5109.
    • (2005) J. Immunol. , vol.174 , pp. 5100-5109
    • Zielinski, C.E.1    Jacob, S.N.2    Bouzahzah, F.3    Ehrlich, B.E.4    Craft, J.5
  • 93
    • 0032518439 scopus 로고    scopus 로고
    • Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice
    • Balomenos, D., R. Rumold, and A. N. Theofilopoulos. 1998. Interferon-γ is required for lupus-like disease and lymphoaccumulation in MRL-lpr mice. J. Clin. Invest. 101: 364-371.
    • (1998) J. Clin. Invest. , vol.101 , pp. 364-371
    • Balomenos, D.1    Rumold, R.2    Theofilopoulos, A.N.3
  • 94
    • 0029914331 scopus 로고    scopus 로고
    • Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo
    • DOI 10.1146/annurev.immunol.14.1.207
    • Kagi, D., B. Ledermann, K. Burki, R. M. Zinkernagel, and H. Hengartner. 1996. Molecular mechanisms of lymphocyte-mediated cytotoxicity and their role in immunological protection and pathogenesis in vivo. Annu. Rev. Immunol. 14: 207-232. (Pubitemid 26130183)
    • (1996) Annual Review of Immunology , vol.14 , pp. 207-232
    • Kagi, D.1    Ledermann, B.2    Burki, K.3    Zinkernagel, R.M.4    Hengartner, H.5
  • 96
    • 0031974934 scopus 로고    scopus 로고
    • Perforin protects against autoimmunity in lupus-prone mice
    • Peng, S. L., J. Moslehi, M. E. Robert, and J. Craft. 1998. Perforin protects against autoimmunity in lupus-prone mice. J. Immunol. 160: 652-660.
    • (1998) J. Immunol. , vol.160 , pp. 652-660
    • Peng, S.L.1    Moslehi, J.2    Robert, M.E.3    Craft, J.4
  • 97
    • 0028932731 scopus 로고
    • The CTL's kiss of death
    • Berke, G. 1995. The CTL's kiss of death. Cell 81: 9-12.
    • (1995) Cell , vol.81 , pp. 9-12
    • Berke, G.1
  • 99
    • 84904029000 scopus 로고    scopus 로고
    • Overview of cellular immune function in systemic lupus erythematosus
    • R. G. Lahita, ed. Elsevier, Amsterdam
    • Tsokos, G. C. 2004. Overview of cellular immune function in systemic lupus erythematosus. In Systemic Lupus Erythematosus. R. G. Lahita, ed. Elsevier, Amsterdam, pp. 29-92.
    • (2004) Systemic Lupus Erythematosus , pp. 29-92
    • Tsokos, G.C.1
  • 100
    • 0024246214 scopus 로고
    • + T helper cell function in association with autoimmunity
    • + T helper cell function in association with autoimmunity. J. Exp. Med. 168: 2165-2181.
    • (1988) J. Exp. Med. , vol.168 , pp. 2165-2181
    • Via, C.S.1    Shearer, G.M.2
  • 101
    • 0027208746 scopus 로고
    • T cell-antigen-presenting cell interactions in human systemic lupus erythematosus: Evidence for heterogeneous expression of multiple defects
    • Via, C. S., G. C. Tsokos, B. Bermas, M. Clerici, and G. M. Shearer. 1993. T cell-antigen-presenting cell interactions in human systemic lupus erythematosus: evidence for heterogeneous expression of multiple defects. J. Immunol. 151: 3914-3922.
    • (1993) J. Immunol. , vol.151 , pp. 3914-3922
    • Via, C.S.1    Tsokos, G.C.2    Bermas, B.3    Clerici, M.4    Shearer, G.M.5
  • 102
    • 0037120006 scopus 로고    scopus 로고
    • H-derived major histocompatibility complex class I-binding epitopes activates cytotoxic T cells that ablate autoantibody-producing B cells and inhibit lupus
    • H-derived major histocompatibility complex class I-binding epitopes activates cytotoxic T cells that ablate autoantibody-producing B cells and inhibit lupus. J. Exp. Med. 196: 731-741.
    • (2002) J. Exp. Med. , vol.196 , pp. 731-741
    • Fan, G.C.1    Singh, R.R.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.