Measurement of daughter cell accumulation during lymphocyte proliferation in vivo

Journal of Immunological Methods

Volumn 295, Issue 1-2, 2004, Pages 79-87

  Thompson, Bruce S ^a   Mitchell, Thomas C ^a,b  

^a University of Louisville School of Medicine   (United States)

^b UNIVERSITY OF LOUISVILLE   (United States)

Author keywords

CFSE; Clonal expansion; Daughter cell accumulation; Lymphocyte; Mitogenesis; Mouse; Survival; T cell

Indexed keywords

ANTIGEN; CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; IMMUNOLOGICAL ADJUVANT; LIPOPOLYSACCHARIDE; 5 (6) CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; 5-(6)-CARBOXYFLUORESCEIN DIACETATE SUCCINIMIDYL ESTER; FLUORESCEIN DERIVATIVE; FLUORESCENT DYE; SUCCINIMIDE DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CALCULATION; CELL; CELL COUNT; CELL CYCLE; CELL DEATH; CELL DIVISION; CELL LABELING; CHEMICAL LABELING; CONTROLLED STUDY; DAUGHTER CELL; EXPERIMENTAL MOUSE; IN VIVO STUDY; LYMPHOCYTE PROLIFERATION; MEASUREMENT; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; STANDARD; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THEORETICAL STUDY; ANIMAL; CELL PROLIFERATION; DRUG EFFECT; FLOW CYTOMETRY; LYMPHOCYTE; METHODOLOGY; PHYSIOLOGY; SENSITIVITY AND SPECIFICITY; TRANSGENIC MOUSE;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL COUNT; CELL PROLIFERATION; FLOW CYTOMETRY; FLUORESCEINS; FLUORESCENT DYES; LYMPHOCYTES; MICE; MICE, TRANSGENIC; SENSITIVITY AND SPECIFICITY; SUCCINIMIDES;

EID: 13844316916     PISSN: 00221759     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jim.2004.09.008     Document Type: Article

References (11)

1. E.K. Deenick, A.V. Gett, and P.D. Hodgkin Stochastic model of T cell proliferation: a calculus revealing IL-2 regulation of precursor frequencies, cell cycle time, and survival J. Immunol. 170 10 2003 4963
2. A.V. Gett, and P.D. Hodgkin A cellular calculus for signal integration by T cells Nat. Immunol. 1 3 2000 239
3. S. Hou, L. Hyland, K.W. Ryan, A. Portner, and P.C. Doherty Virus-specific CD8+ T cell memory determined by clonal burst size Nature 369 1994 652
4. T. Kaisho, and S. Akira Regulation of dendritic cell function through Toll-like receptors Curr. Mol. Med. 3 4 2003 373
5. E.R. Kearney, K.A. Pape, D.Y. Loh, and M.K. Jenkins Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo Immunity 1 4 1994 327
6. A.B. Lyons, and C.R. Parish Determination of lymphocyte division by flow cytometry J. Immunol. Methods 171 1 1994 131
7. T.C. Mitchell, J. Kappler, and P. Marrack Bystander virus infection prolongs activated T cell survival J. Immunol. 162 8 1999 4527
8. E.J. Suchin, P.B. Langmuir, E. Palmer, M.H. Sayegh, A.D. Wells, and L.A. Turka Quantifying the frequency of alloreactive T cells in vivo: new answers to an old question J. Immunol. 166 2 2001 973
9. K. Takeda, T. Kaisho, and S. Akira Toll-like receptors Annu. Rev. Immunol. 21 2003 335
10. A.T. Vella, J.E. McCormack, P.S. Linsley, J.W. Kappler, and P. Marrack Lipopolysaccharide interferes with the induction of peripheral T cell death Immunity 2 3 1995 261
11. A.D. Wells, H. Gudmundsdottir, and L.A. Turka Following the fate of individual T cells throughout activation and clonal expansion. Signals from T cell receptor and CD28 differentially regulate the induction and duration of a proliferative response J. Clin. Invest. 100 12 1997 3173