Maximal proliferation of cytotoxic T lymphocytes requires reverse signaling through Fas ligand

Journal of Experimental Medicine

Volumn 187, Issue 1, 1998, Pages 123-128

  Suzuki, Ivy ^a   Fink, Pamela J ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; FAS ANTIGEN; FAS LIGAND; HYBRID PROTEIN; IMMUNOGLOBULIN G1; MONOCLONAL ANTIBODY CD3;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; IMMUNOSTIMULATION; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; ANTIGENS, CD95; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE; FAS LIGAND PROTEIN; HUMANS; LYMPHOCYTE ACTIVATION; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C3H; MICE, INBRED C57BL; MICE, SCID; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0031973637     PISSN: 00221007     EISSN: None     Source Type: Journal    
DOI: 10.1084/jem.187.1.123     Document Type: Article

References (30)

1. Nagata, S., and P. Golstein. 1995. The fas death factor. Science. 267:1449-1456.
2. Gruss, H.-J., and S.K. Dower. 1995. Tumor necrosis factor ligand superfamily: involvement in the pathology of malignant lymphomas. Blood. 85:3378-3404.
3. Smith, C.G., T. Farrah, and R.G. Goodwin. 1994. The TNF receptor superfamily of cellular and viral proteins: activation, costimulation, and death. Cell. 76:959-962.
4. Stuber, E., M. Neurath, D. Calderhead, H.P. Fell, and W. Strober. 1995. Cross-linking of OX40 ligand, a member of the TNF/NGF cytokine family, induces proliferation and differentiation in murine splenic B cells. Immunity. 2:507-521.
5. Wiley, S.R., R.G. Goodwin, and C.A. Smith. 1996. Reverse signaling via CD30 ligand. J. Immunol. 157:3635-3639.
6. 2+-independent T cell-mediated cytotoxicity. J. Exp. Med. 177:195-200.
7. Ceredig, R., J.W. Lowenthal, M. Nabholz, and H.R. MacDonald. 1985. Expression of interleukin-2 receptors as a differentiation marker on intrathymic stem cells. Nature. 314: 98-100.
8. Sarmiento, M., A.L. Glasebrook, and F.W. Fitch. 1980. IgG or IgM monoclonal antibodies reactive with different determinants on the molecular complex bearing Lyt-2 antigen block T cell-mediated cytolysis in the absence of complement. J. Immunol. 125:2665-2672.
9. Ozato, K., N. Mayer, and D.H. Sachs. 1980. Hybridoma cell lines secreting monoclonal antibodies to mouse H-2 and Ia antigens. J. Immunol. 124:533-540.
10. Ju, S.-T., D.J. Panka, H. Cui, R. Ettinger, M. El-Khatib, D.H. Sherr, B.Z. Stanger, and A. Marshak-Rothstein. 1995. Fas(CD95)/FasL interactions required for programmed cell death after T cell activation. Nature. 373:444-148.
11. Brunner, T., R.J. Mogil, D. LaFace, N.J. Yoo, A. Mahboubi, F. Echeverri, S.J. Martin, W.R. Force, D.H. Lynch, C.F. Ware, and D.R. Green. 1995. Cell-autonomous Fas(CD95)/ Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature. 373:441-444.
12. Dhein, J., H. Walczak, C. Baumier, K.-M. Debatin, and P.H. Krammer. 1995. Autocrine T-cell suicide mediated by APO-1/ (Fas/CD95). Nature. 373:438-441.
13. Lynch, D.H., M.L. Watson, M.R. Alderson, P.R. Baum, R.E. Miller, T. Tough, M. Gibson, T. Davis-Smith, C.A. Smith, K. Hunter, et al. 1994. The mouse Fas-ligand gene is mutated in gld mice and is part of a TNF family gene cluster. Immunity. 1:131-136.
14. Takahashi, T., M. Tanaka, C.I. Brannan, N.A. Jenkins, N.G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell. 76:969-976.
15. Ren, R., B.J. Mayer, P. Cicchetti, and D. Baltimore. 1993. Identification of a ten-amino acid proline-rich SH3 binding site. Science. 259:1157-1161.
16. Zheng, L., G. Fisher, R.E. Miller, J. Peschon, D.H. Lynch, and M.J. Lenardo. 1995. Induction of apoptosis in mature T cells by tumour necrosis factor. Nature. 377:348-351.
17. Ehl, S., U. Hoffmann-Rohrer, S. Nagata, H. Hengartner, and R. Zinkernagel. 1996. Different susceptibility of cytotoxic T cells to CD95 (Fas/Apo-1) ligand-mediated cell death after activation in vitro versus in vivo. J. Immunol. 156:2357-2360.
18. Sytwu, H.-K., R.S. Liblau, and H.O. McDevitt. 1996. The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity. 5:17-30.
19. + T cells responding to a bacterial superantigen. J. Immunol. 154:4302-4308.
20. Russell, J.H., and R. Wang. 1993. Autoimmune gld mutation uncouples suicide and cytokine/proliferation pathways in activated mature T cells. Eur. J. Immunol. 23:2379-2382.
21. Rathmell, J.C., S.E. Townsend, J.C. Xu, R.A. Flavell and C.C. Goodnow. 1996. Expansion or elimination of B cells in vivo: dual roles for CD40-and Fas (CD95)-ligands modulated by the B cell antigen receptor. Cell 87:319-329.
22. Rothstein, T.L., J.K.M. Wang, D-J. Panka, L.C. Foote, Z. Wang, B. Stanger, H. Cui, S.-T. Ju, and A. Marshak-Rothstein. 1995. Protection against Fas-dependent Th1-mediated apoptosis by antigen receptor engagement in B cells. Nature. 374:163-165.
23. Arpin, C., J. Dechanet, C. Van Kooten, P. Merville, G. Brouard, F. Briere, J. Banchereau, and Y.-J. Liu. 1995. Generation of memory B cells and plasma cells in vitro. Science. 268:720-722.
24. Hogquist, K.A., S.G. Jameson, W.R. Heath, J.L. Howard, M.J. Bevan, and F.R. Carbone. 1994. T cell receptor antagonist peptides induce positive selection. Cell. 76:17-27.
25. Alderson, M.R., R.J. Armitage, E. Maraskovsky, T.W. Tough, E. Roux, K. Schooley, F. Ramsdell, and D.H. Lynch. 1993. Fas transduces activation signals in normal human T lymphocytes. J. Exp. Med. 178:2231-2235.
26. Mapara, M.Y., R. Bargou, C. Zugck, H. Dohmer, F. Ustaoglu, R.R. Jonker, P.H. Krammer, and B. Dorken. 1993. APO-1 mediated apoptosis or proliferation in human chronic B lymphocytic leukemia: correlation with bcl-2 oncogene expression. Eur. J. Immunol. 3:702-708.
27. Tewari, M., and V.M. Dixit. 1996. Recent advances in tumor necrosis factor and CD40 signaling. Curr. Opin. Genet. Dev. 6:39-44.
28. Tartaglia, L.A., and D.V. Goeddel. 1992. Two TNF receptors. Immunol. Today. 13:151-153.
29. Duckett, C.S., R.W. Gedrich, M.C. Gilfillan, and C.B. Thompson. 1997. Induction of nuclear factor κB by the CD30 receptor is mediated by TRAF1 and TRAF2. Mol. Cell. Biol. 17:1535-1542.
30. Walunas, T.L., D.J. Lenschow, C.Y. Bakker, P.S. Linsley, G.J. Freeman, J.M. Green, C.B. Thompson, and J.A. Bluestone. 1994. CTLA-4 can function as a negative regulator of T cell activation. Immunity. 1:405-113.