-
1
-
-
48449090686
-
DNA replication stalling attenuates tyrosine kinase signaling to suppress S phase progression
-
Shields BJ, Hauser C, Bukczynska PE, Court NW, Tiganis T. DNA replication stalling attenuates tyrosine kinase signaling to suppress S phase progression. Cancer Cell 2008; 14:166-79.
-
(2008)
Cancer Cell
, vol.14
, pp. 166-179
-
-
Shields, B.J.1
Hauser, C.2
Bukczynska, P.E.3
Court, N.W.4
Tiganis, T.5
-
2
-
-
9244251125
-
Cell cycle checkpoints and cancer
-
Kastan MB, Bartek J. Cell cycle checkpoints and cancer. Nature 2004; 432:316-23.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
4
-
-
47749141560
-
ATR: An essential regulator of genome integrity
-
Cimprich KA, Cortez D. ATR: an essential regulator of genome integrity. Nat Rev Mol Cell Biol 2008; 9:616-27.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 616-627
-
-
Cimprich, K.A.1
Cortez, D.2
-
5
-
-
0034177408
-
Targeted disruption of the cell cycle checkpoint gene ATR leads to early embryonic lethality in mice
-
de Klein A, Muijtjens M, van Os R, Verhoeven Y, Smit B, Carr AM, et al. Targeted disruption of the cell cycle checkpoint gene ATR leads to early embryonic lethality in mice. Curr Biol 2000; 10:479-82.
-
(2000)
Curr Biol
, vol.10
, pp. 479-482
-
-
de Klein, A.1
Muijtjens, M.2
van Os, R.3
Verhoeven, Y.4
Smit, B.5
Carr, A.M.6
-
6
-
-
0035941021
-
ATR and ATRIP: Partners in checkpoint signaling
-
Cortez D, Guntuku S, Qin J, Elledge SJ. ATR and ATRIP: partners in checkpoint signaling. Science 2001; 294:1713-6.
-
(2001)
Science
, vol.294
, pp. 1713-1716
-
-
Cortez, D.1
Guntuku, S.2
Qin, J.3
Elledge, S.J.4
-
7
-
-
0037335861
-
Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance
-
Brown EJ, Baltimore D. Essential and dispensable roles of ATR in cell cycle arrest and genome maintenance. Genes Dev 2003; 17:615-28.
-
(2003)
Genes Dev
, vol.17
, pp. 615-628
-
-
Brown, E.J.1
Baltimore, D.2
-
11
-
-
0038418869
-
Chk1 and Chk2 kinases in checkpoint control and cancer
-
Bartek J, Lukas J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell 2003; 3:421-9.
-
(2003)
Cancer Cell
, vol.3
, pp. 421-429
-
-
Bartek, J.1
Lukas, J.2
-
12
-
-
0037178748
-
Interfaces between the detection, signaling and repair of DNA damage
-
Rouse J, Jackson SP. Interfaces between the detection, signaling and repair of DNA damage. Science 2002; 297:547-51.
-
(2002)
Science
, vol.297
, pp. 547-551
-
-
Rouse, J.1
Jackson, S.P.2
-
13
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham RT. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev 2001; 15:2177-96.
-
(2001)
Genes Dev
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
14
-
-
0026562544
-
2 checkpoint pathways in Schizosaccharomyces pombe
-
2 checkpoint pathways in Schizosaccharomyces pombe. Embo J 1992; 11:1343-50.
-
(1992)
Embo J
, vol.11
, pp. 1343-1350
-
-
al-Khodairy, F.1
Carr, A.M.2
-
15
-
-
0026482601
-
Fission yeast genes involved in coupling mitosis to completion of DNA replication
-
Enoch T, Carr AM, Nurse P. Fission yeast genes involved in coupling mitosis to completion of DNA replication. Genes Dev 1992; 6:2035-46.
-
(1992)
Genes Dev
, vol.6
, pp. 2035-2046
-
-
Enoch, T.1
Carr, A.M.2
Nurse, P.3
-
16
-
-
0028353634
-
Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
-
Weinert TA, Kiser GL, Hartwell LH. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev 1994; 8:652-65.
-
(1994)
Genes Dev
, vol.8
, pp. 652-665
-
-
Weinert, T.A.1
Kiser, G.L.2
Hartwell, L.H.3
-
17
-
-
0032496322
-
Replication checkpoint enforced by kinases Cds1 and Chk1
-
Boddy MN, Furnari B, Mondesert O, Russell P. Replication checkpoint enforced by kinases Cds1 and Chk1. Science 1998; 280:909-12.
-
(1998)
Science
, vol.280
, pp. 909-912
-
-
Boddy, M.N.1
Furnari, B.2
Mondesert, O.3
Russell, P.4
-
18
-
-
33847028014
-
Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: Relation to cell cycle phase
-
Tanaka T, Halicka HD, Traganos F, Seiter K, Darzynkiewicz Z. Induction of ATM activation, histone H2AX phosphorylation and apoptosis by etoposide: relation to cell cycle phase. Cell Cycle 2007; 6:371-6.
-
(2007)
Cell Cycle
, vol.6
, pp. 371-376
-
-
Tanaka, T.1
Halicka, H.D.2
Traganos, F.3
Seiter, K.4
Darzynkiewicz, Z.5
-
19
-
-
0003418645
-
A restriction point for control of normal animal cell proliferation
-
Pardee AB. A restriction point for control of normal animal cell proliferation. Proc Natl Acad Sci USA 1974; 71:1286-90.
-
(1974)
Proc Natl Acad Sci USA
, vol.71
, pp. 1286-1290
-
-
Pardee, A.B.1
-
20
-
-
0024473604
-
-
1 events and regulation of cell proliferation. Science 1989; 246:603-8.
-
1 events and regulation of cell proliferation. Science 1989; 246:603-8.
-
-
-
-
21
-
-
0035150990
-
Growth-factor-dependent mitogenesis requires two distinct phases of signaling
-
Jones SM, Kazlauskas A. Growth-factor-dependent mitogenesis requires two distinct phases of signaling. Nat Cell Biol 2001; 3:165-72.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 165-172
-
-
Jones, S.M.1
Kazlauskas, A.2
-
22
-
-
0035895621
-
Growth factor-dependent signaling and cell cycle progression
-
Jones SM, Kazlauskas A. Growth factor-dependent signaling and cell cycle progression. FEBS Lett 2001; 490:110-6.
-
(2001)
FEBS Lett
, vol.490
, pp. 110-116
-
-
Jones, S.M.1
Kazlauskas, A.2
-
24
-
-
0033572412
-
Inhibition of Src kinases by a selective tyrosine kinase inhibitor causes mitotic arrest
-
Moasser MM, Srethapakdi M, Sachar KS, Kraker AJ, Rosen N. Inhibition of Src kinases by a selective tyrosine kinase inhibitor causes mitotic arrest. Cancer Res 1999; 59:6145-52.
-
(1999)
Cancer Res
, vol.59
, pp. 6145-6152
-
-
Moasser, M.M.1
Srethapakdi, M.2
Sachar, K.S.3
Kraker, A.J.4
Rosen, N.5
-
25
-
-
0012644537
-
Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling
-
Tominaga T, Sahai E, Chardin P, McCormick F, Courtneidge SA, Alberts AS. Diaphanous-related formins bridge Rho GTPase and Src tyrosine kinase signaling. Mol Cell 2000; 5:13-25.
-
(2000)
Mol Cell
, vol.5
, pp. 13-25
-
-
Tominaga, T.1
Sahai, E.2
Chardin, P.3
McCormick, F.4
Courtneidge, S.A.5
Alberts, A.S.6
-
26
-
-
0029910050
-
Radicicol inhibits tyrosine phosphorylation of the mitotic Src substrate Sam68 and retards subsequent exit from mitosis of Src-transformed cells
-
Pillay I, Nakano H, Sharma SV. Radicicol inhibits tyrosine phosphorylation of the mitotic Src substrate Sam68 and retards subsequent exit from mitosis of Src-transformed cells. Cell Growth Differ 1996; 7:1487-99.
-
(1996)
Cell Growth Differ
, vol.7
, pp. 1487-1499
-
-
Pillay, I.1
Nakano, H.2
Sharma, S.V.3
-
28
-
-
27144473914
-
The extracellular matrix guides the orientation of the cell division axis
-
Thery M, Racine V, Pepin A, Piel M, Chen Y, Sibarita JB, et al. The extracellular matrix guides the orientation of the cell division axis. Nat Cell Biol 2005; 7:947-53.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 947-953
-
-
Thery, M.1
Racine, V.2
Pepin, A.3
Piel, M.4
Chen, Y.5
Sibarita, J.B.6
-
29
-
-
33749475259
-
Inhibition of the janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication
-
Reiterer G, Yen A. Inhibition of the janus kinase family increases extracellular signal-regulated kinase 1/2 phosphorylation and causes endoreduplication. Cancer Res 2006; 66:9083-9.
-
(2006)
Cancer Res
, vol.66
, pp. 9083-9089
-
-
Reiterer, G.1
Yen, A.2
-
30
-
-
12244288351
-
The protein tyrosine phosphatase PTP-BL associates with the midbody and is involved in the regulation of cytokinesis
-
Herrmann L, Dittmar T, Erdmann KS. The protein tyrosine phosphatase PTP-BL associates with the midbody and is involved in the regulation of cytokinesis. Mol Biol Cell 2003; 14:230-40.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 230-240
-
-
Herrmann, L.1
Dittmar, T.2
Erdmann, K.S.3
-
31
-
-
0345593816
-
Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration and cytokinesis in fibroblasts
-
Angers-Loustau A, Cote JF, Charest A, Dowbenko D, Spencer S, Lasky LA, et al. Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration and cytokinesis in fibroblasts. J Cell Biol 1999; 144:1019-31.
-
(1999)
J Cell Biol
, vol.144
, pp. 1019-1031
-
-
Angers-Loustau, A.1
Cote, J.F.2
Charest, A.3
Dowbenko, D.4
Spencer, S.5
Lasky, L.A.6
-
32
-
-
0034510155
-
Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation
-
Cong F, Spencer S, Cote JF, Wu Y, Tremblay ML, Lasky LA, et al. Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation. Mol Cell 2000; 6:1413-23.
-
(2000)
Mol Cell
, vol.6
, pp. 1413-1423
-
-
Cong, F.1
Spencer, S.2
Cote, J.F.3
Wu, Y.4
Tremblay, M.L.5
Lasky, L.A.6
-
33
-
-
55849151273
-
Cell cycle-dependent regulation of SFK, JAK1 and STAT3 signaling by the protein tyrosine phosphatase TCPTP
-
Shields BJ, Court NW, Hauser C, Bukczynska PE, Tiganis T. Cell cycle-dependent regulation of SFK, JAK1 and STAT3 signaling by the protein tyrosine phosphatase TCPTP. Cell Cycle 2008; 7:3405-16.
-
(2008)
Cell Cycle
, vol.7
, pp. 3405-3416
-
-
Shields, B.J.1
Court, N.W.2
Hauser, C.3
Bukczynska, P.E.4
Tiganis, T.5
-
34
-
-
0037077275
-
Mitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylation
-
Zheng XM, Resnick RJ, Shalloway D. Mitotic activation of protein-tyrosine phosphatase alpha and regulation of its Src-mediated transforming activity by its sites of protein kinase C phosphorylation. J Biol Chem 2002; 277:21922-9.
-
(2002)
J Biol Chem
, vol.277
, pp. 21922-21929
-
-
Zheng, X.M.1
Resnick, R.J.2
Shalloway, D.3
-
35
-
-
0035503358
-
Two mechanisms activate PTPalpha during mitosis
-
Zheng XM, Shalloway D. Two mechanisms activate PTPalpha during mitosis. Embo J 2001; 20:6037-49.
-
(2001)
Embo J
, vol.20
, pp. 6037-6049
-
-
Zheng, X.M.1
Shalloway, D.2
-
36
-
-
0030992749
-
Interaction between ATM protein and c-Abl in response to DNA damage
-
Shafman T, Khanna KK, Kedar P, Spring K, Kozlov S, Yen T, et al. Interaction between ATM protein and c-Abl in response to DNA damage. Nature 1997; 387:520-3.
-
(1997)
Nature
, vol.387
, pp. 520-523
-
-
Shafman, T.1
Khanna, K.K.2
Kedar, P.3
Spring, K.4
Kozlov, S.5
Yen, T.6
-
37
-
-
0033600240
-
Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis
-
Agami R, Blandino G, Oren M, Shaul Y. Interaction of c-Abl and p73alpha and their collaboration to induce apoptosis. Nature 1999; 399:809-13.
-
(1999)
Nature
, vol.399
, pp. 809-813
-
-
Agami, R.1
Blandino, G.2
Oren, M.3
Shaul, Y.4
-
38
-
-
38949123978
-
Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage
-
Levy D, Adamovich Y, Reuven N, Shaul Y. Yap1 phosphorylation by c-Abl is a critical step in selective activation of proapoptotic genes in response to DNA damage. Mol Cell 2008; 29:350-61.
-
(2008)
Mol Cell
, vol.29
, pp. 350-361
-
-
Levy, D.1
Adamovich, Y.2
Reuven, N.3
Shaul, Y.4
-
39
-
-
0033600235
-
p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage
-
Yuan ZM, Shioya H, Ishiko T, Sun X, Gu J, Huang YY, et al. p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage. Nature 1999; 399:814-7.
-
(1999)
Nature
, vol.399
, pp. 814-817
-
-
Yuan, Z.M.1
Shioya, H.2
Ishiko, T.3
Sun, X.4
Gu, J.5
Huang, Y.Y.6
-
40
-
-
0242353362
-
2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase
-
2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase. J Biol Chem 2003; 278:42812-20.
-
(2003)
J Biol Chem
, vol.278
, pp. 42812-42820
-
-
Yuan, L.1
Yu, W.M.2
Qu, C.K.3
-
41
-
-
30044448590
-
2/M arrest in catalytically dependent and independent manners, respectively
-
2/M arrest in catalytically dependent and independent manners, respectively. J Biol Chem 2005; 280:42701-6.
-
(2005)
J Biol Chem
, vol.280
, pp. 42701-42706
-
-
Yuan, L.1
Yu, W.M.2
Xu, M.3
Qu, C.K.4
-
42
-
-
0038012669
-
Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response
-
Yuan L, Yu WM, Yuan Z, Haudenschild CC, Qu CK. Role of SHP-2 tyrosine phosphatase in the DNA damage-induced cell death response. J Biol Chem 2003; 278:15208-16.
-
(2003)
J Biol Chem
, vol.278
, pp. 15208-15216
-
-
Yuan, L.1
Yu, W.M.2
Yuan, Z.3
Haudenschild, C.C.4
Qu, C.K.5
-
43
-
-
1642421759
-
BCR/ABL translocates to the nucleus and disrupts an ATR-dependent intra-S phase checkpoint
-
Dierov J, Dierova R, Carroll M. BCR/ABL translocates to the nucleus and disrupts an ATR-dependent intra-S phase checkpoint. Cancer Cell 2004; 5:275-85.
-
(2004)
Cancer Cell
, vol.5
, pp. 275-285
-
-
Dierov, J.1
Dierova, R.2
Carroll, M.3
-
44
-
-
0035797444
-
Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint
-
Tercero JA, Diffley JF. Regulation of DNA replication fork progression through damaged DNA by the Mec1/Rad53 checkpoint. Nature 2001; 412:553-7.
-
(2001)
Nature
, vol.412
, pp. 553-557
-
-
Tercero, J.A.1
Diffley, J.F.2
-
45
-
-
2442582392
-
Visualization of altered replication dynamics after DNA damage in human cells
-
Merrick CJ, Jackson D, Diffley JF. Visualization of altered replication dynamics after DNA damage in human cells. J Biol Chem 2004; 279:20067-75.
-
(2004)
J Biol Chem
, vol.279
, pp. 20067-20075
-
-
Merrick, C.J.1
Jackson, D.2
Diffley, J.F.3
-
46
-
-
0036033161
-
The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation
-
Yamamoto T, Sekine Y, Kashima K, Kubota A, Sato N, Aoki N, et al. The nuclear isoform of protein-tyrosine phosphatase TC-PTP regulates interleukin-6-mediated signaling pathway through STAT3 dephosphorylation. Biochem Biophys Res Commun 2002; 297:811-7.
-
(2002)
Biochem Biophys Res Commun
, vol.297
, pp. 811-817
-
-
Yamamoto, T.1
Sekine, Y.2
Kashima, K.3
Kubota, A.4
Sato, N.5
Aoki, N.6
-
47
-
-
0036006288
-
The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3
-
Simoncic PD, Lee-Loy A, Barber DL, Tremblay ML, McGlade CJ. The T cell protein tyrosine phosphatase is a negative regulator of janus family kinases 1 and 3. Curr Biol 2002; 12:446-53.
-
(2002)
Curr Biol
, vol.12
, pp. 446-453
-
-
Simoncic, P.D.1
Lee-Loy, A.2
Barber, D.L.3
Tremblay, M.L.4
McGlade, C.J.5
-
48
-
-
14944349510
-
Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase
-
van Vliet C, Bukczynska PE, Puryer MA, Sadek CM, Shields BJ, Tremblay ML, et al. Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphatase. Nat Immunol 2005; 6:253-60.
-
(2005)
Nat Immunol
, vol.6
, pp. 253-260
-
-
van Vliet, C.1
Bukczynska, P.E.2
Puryer, M.A.3
Sadek, C.M.4
Shields, B.J.5
Tremblay, M.L.6
-
49
-
-
33846945811
-
Protein tyrosine phosphatase function: The substrate perspective
-
Tiganis T, Bennett AM. Protein tyrosine phosphatase function: the substrate perspective. Biochem J 2007; 402:1-15.
-
(2007)
Biochem J
, vol.402
, pp. 1-15
-
-
Tiganis, T.1
Bennett, A.M.2
-
52
-
-
0027958344
-
Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines
-
Lukas J, Pagano M, Staskova Z, Draetta G, Bartek J. Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines. Oncogene 1994; 9:707-18.
-
(1994)
Oncogene
, vol.9
, pp. 707-718
-
-
Lukas, J.1
Pagano, M.2
Staskova, Z.3
Draetta, G.4
Bartek, J.5
-
53
-
-
0028129498
-
Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts
-
Pagano M, Theodoras AM, Tam SW, Draetta GF. Cyclin D1-mediated inhibition of repair and replicative DNA synthesis in human fibroblasts. Genes Dev 1994; 8:1627-39.
-
(1994)
Genes Dev
, vol.8
, pp. 1627-1639
-
-
Pagano, M.1
Theodoras, A.M.2
Tam, S.W.3
Draetta, G.F.4
-
54
-
-
0033533724
-
Cyclin D1 production in cycling cells depends on ras in a cell cycle-specific manner
-
Hitomi M, Stacey DW. Cyclin D1 production in cycling cells depends on ras in a cell cycle-specific manner. Curr Biol 1999; 9:1075-84.
-
(1999)
Curr Biol
, vol.9
, pp. 1075-1084
-
-
Hitomi, M.1
Stacey, D.W.2
-
55
-
-
13944249549
-
Destabilization of cyclin D1 message plays a critical role in cell cycle exit upon mitogen withdrawal
-
Guo Y, Harwalkar J, Stacey DW, Hitomi M. Destabilization of cyclin D1 message plays a critical role in cell cycle exit upon mitogen withdrawal. Oncogene 2005; 24:1032-42.
-
(2005)
Oncogene
, vol.24
, pp. 1032-1042
-
-
Guo, Y.1
Harwalkar, J.2
Stacey, D.W.3
Hitomi, M.4
-
56
-
-
34247167103
-
Variations in cyclin D1 levels through the cell cycle determine the proliferative fate of a cell
-
Yang K, Hitomi M, Stacey DW. Variations in cyclin D1 levels through the cell cycle determine the proliferative fate of a cell. Cell Div 2006; 1:32.
-
(2006)
Cell Div
, vol.1
, pp. 32
-
-
Yang, K.1
Hitomi, M.2
Stacey, D.W.3
-
57
-
-
0026459047
-
D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA
-
Xiong Y, Zhang H, Beach D. D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell 1992; 71:505-14.
-
(1992)
Cell
, vol.71
, pp. 505-514
-
-
Xiong, Y.1
Zhang, H.2
Beach, D.3
-
58
-
-
0033080511
-
Cyclin D1 inhibits cell proliferation through binding to PCNA and cdk2
-
Fukami-Kobayashi J, Mitsui Y. Cyclin D1 inhibits cell proliferation through binding to PCNA and cdk2. Exp Cell Res 1999; 246:338-47.
-
(1999)
Exp Cell Res
, vol.246
, pp. 338-347
-
-
Fukami-Kobayashi, J.1
Mitsui, Y.2
-
59
-
-
0034611749
-
The Cdt1 protein is required to license DNA for replication in fission yeast
-
Nishitani H, Lygerou Z, Nishimoto T, Nurse P. The Cdt1 protein is required to license DNA for replication in fission yeast. Nature 2000; 404:625-8.
-
(2000)
Nature
, vol.404
, pp. 625-628
-
-
Nishitani, H.1
Lygerou, Z.2
Nishimoto, T.3
Nurse, P.4
-
60
-
-
0034611807
-
XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis
-
Maiorano D, Moreau J, Mechali M. XCDT1 is required for the assembly of pre-replicative complexes in Xenopus laevis. Nature 2000; 404:622-5.
-
(2000)
Nature
, vol.404
, pp. 622-625
-
-
Maiorano, D.1
Moreau, J.2
Mechali, M.3
-
61
-
-
36248975284
-
Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication
-
Aggarwal P, Lessie MD, Lin DI, Pontano L, Gladden AB, Nuskey B, et al. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes Dev 2007; 21:2908-22.
-
(2007)
Genes Dev
, vol.21
, pp. 2908-2922
-
-
Aggarwal, P.1
Lessie, M.D.2
Lin, D.I.3
Pontano, L.4
Gladden, A.B.5
Nuskey, B.6
-
62
-
-
0034616913
-
1 cell cycle arrest in response to DNA damage
-
1 cell cycle arrest in response to DNA damage. Cell 2000; 102:55-66.
-
(2000)
Cell
, vol.102
, pp. 55-66
-
-
Agami, R.1
Bernards, R.2
-
63
-
-
0037041027
-
DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2
-
Lan Z, Sever-Chroneos Z, Strobeck MW, Park CH, Baskaran R, Edelmann W, et al. DNA damage invokes mismatch repair-dependent cyclin D1 attenuation and retinoblastoma signaling pathways to inhibit CDK2. J Biol Chem 2002; 277:8372-81.
-
(2002)
J Biol Chem
, vol.277
, pp. 8372-8381
-
-
Lan, Z.1
Sever-Chroneos, Z.2
Strobeck, M.W.3
Park, C.H.4
Baskaran, R.5
Edelmann, W.6
-
64
-
-
50249184808
-
Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression
-
Hitomi M, Yang K, Stacey AW, Stacey DW. Phosphorylation of cyclin D1 regulated by ATM or ATR controls cell cycle progression. Mol Cell Biol 2008; 28:5478-93.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 5478-5493
-
-
Hitomi, M.1
Yang, K.2
Stacey, A.W.3
Stacey, D.W.4
-
65
-
-
57349191639
-
Genotoxic Stress-Induced Cyclin D1 Phosphorylation and Proteolysis is Required for Genomic Stability
-
Pontano LL, Aggarwal P, Barbash O, Brown EJ, Bassing CH, Diehl JA. Genotoxic Stress-Induced Cyclin D1 Phosphorylation and Proteolysis is Required for Genomic Stability. Mol Cell Biol 2008; 28:7245-58.
-
(2008)
Mol Cell Biol
, vol.28
, pp. 7245-7258
-
-
Pontano, L.L.1
Aggarwal, P.2
Barbash, O.3
Brown, E.J.4
Bassing, C.H.5
Diehl, J.A.6
-
66
-
-
0036316015
-
Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells
-
Lundin C, Erixon K, Arnaudeau C, Schultz N, Jenssen D, Meuth M, et al. Different roles for nonhomologous end joining and homologous recombination following replication arrest in mammalian cells. Mol Cell Biol 2002; 22:5869-78.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 5869-5878
-
-
Lundin, C.1
Erixon, K.2
Arnaudeau, C.3
Schultz, N.4
Jenssen, D.5
Meuth, M.6
-
67
-
-
26444581387
-
Differential roles of XRCC2 in homologous recombinational repair of stalled replication forks
-
Liu N, Lim CS. Differential roles of XRCC2 in homologous recombinational repair of stalled replication forks. J Cell Biochem 2005; 95:942-54.
-
(2005)
J Cell Biochem
, vol.95
, pp. 942-954
-
-
Liu, N.1
Lim, C.S.2
-
68
-
-
23344444636
-
Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks
-
Saleh-Gohari N, Bryant HE, Schultz N, Parker KM, Cassel TN, Helleday T. Spontaneous homologous recombination is induced by collapsed replication forks that are caused by endogenous DNA single-strand breaks. Mol Cell Biol 2005; 25:7158-69.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 7158-7169
-
-
Saleh-Gohari, N.1
Bryant, H.E.2
Schultz, N.3
Parker, K.M.4
Cassel, T.N.5
Helleday, T.6
-
69
-
-
0035898405
-
Characterization of homologous recombination induced by replication inhibition in mammalian cells
-
Saintigny Y, Delacote F, Vares G, Petitot F, Lambert S, Averbeck D, et al. Characterization of homologous recombination induced by replication inhibition in mammalian cells. Embo J 2001; 20:3861-70.
-
(2001)
Embo J
, vol.20
, pp. 3861-3870
-
-
Saintigny, Y.1
Delacote, F.2
Vares, G.3
Petitot, F.4
Lambert, S.5
Averbeck, D.6
-
70
-
-
0042632901
-
Pathways of DNA double-strand break repair during the mammalian cell cycle
-
Rothkamm K, Kruger I, Thompson LH, Lobrich M. Pathways of DNA double-strand break repair during the mammalian cell cycle. Mol Cell Biol 2003; 23:5706-15.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 5706-5715
-
-
Rothkamm, K.1
Kruger, I.2
Thompson, L.H.3
Lobrich, M.4
-
71
-
-
22244474639
-
Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks
-
Lundin C, North M, Erixon K, Walters K, Jenssen D, Goldman AS, et al. Methyl methanesulfonate (MMS) produces heat-labile DNA damage but no detectable in vivo DNA double-strand breaks. Nucleic Acids Res 2005; 33:3799-811.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 3799-3811
-
-
Lundin, C.1
North, M.2
Erixon, K.3
Walters, K.4
Jenssen, D.5
Goldman, A.S.6
-
72
-
-
1042302005
-
The STATs of cancer-new molecular targets come of age
-
Yu H, Jove R. The STATs of cancer-new molecular targets come of age. Nat Rev Cancer 2004; 4:97-105.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 97-105
-
-
Yu, H.1
Jove, R.2
-
73
-
-
0032930674
-
Cyclin D1/PRAD1/BCL-1 alternative transcript [B] protein product in B-lymphoid malignancies with t(11;14)(q13;q32) translocation
-
Hosokawa Y, Joh T, Maeda Y, Arnold A, Seto M. Cyclin D1/PRAD1/BCL-1 alternative transcript [B] protein product in B-lymphoid malignancies with t(11;14)(q13;q32) translocation. Int J Cancer 1999; 81:616-9.
-
(1999)
Int J Cancer
, vol.81
, pp. 616-619
-
-
Hosokawa, Y.1
Joh, T.2
Maeda, Y.3
Arnold, A.4
Seto, M.5
-
74
-
-
0028845142
-
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers
-
Herman JG, Merlo A, Mao L, Lapidus RG, Issa JP, Davidson NE, et al. Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers. Cancer Res 1995; 55:4525-30.
-
(1995)
Cancer Res
, vol.55
, pp. 4525-4530
-
-
Herman, J.G.1
Merlo, A.2
Mao, L.3
Lapidus, R.G.4
Issa, J.P.5
Davidson, N.E.6
-
75
-
-
0028331092
-
Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
-
Gillett C, Fantl V, Smith R, Fisher C, Bartek J, Dickson C, et al. Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 1994; 54:1812-7.
-
(1994)
Cancer Res
, vol.54
, pp. 1812-1817
-
-
Gillett, C.1
Fantl, V.2
Smith, R.3
Fisher, C.4
Bartek, J.5
Dickson, C.6
-
78
-
-
0028260723
-
Cell cycle-related variation and tissue-restricted expression of human cyclin D1 protein
-
Bartkova J, Lukas J, Strauss M, Bartek J. Cell cycle-related variation and tissue-restricted expression of human cyclin D1 protein. J Pathol 1994; 172:237-45.
-
(1994)
J Pathol
, vol.172
, pp. 237-245
-
-
Bartkova, J.1
Lukas, J.2
Strauss, M.3
Bartek, J.4
-
79
-
-
0028129951
-
The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas
-
Bartkova J, Lukas J, Strauss M, Bartek J. The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas. Int J Cancer 1994; 58:568-73.
-
(1994)
Int J Cancer
, vol.58
, pp. 568-573
-
-
Bartkova, J.1
Lukas, J.2
Strauss, M.3
Bartek, J.4
-
80
-
-
0028308702
-
Cyclin D1 protein expression and function in human breast cancer
-
Bartkova J, Lukas J, Muller H, Lutzhoft D, Strauss M, Bartek J. Cyclin D1 protein expression and function in human breast cancer. Int J Cancer 1994; 57:353-61.
-
(1994)
Int J Cancer
, vol.57
, pp. 353-361
-
-
Bartkova, J.1
Lukas, J.2
Muller, H.3
Lutzhoft, D.4
Strauss, M.5
Bartek, J.6
-
81
-
-
0034780882
-
Cyclin D1, p16 and retinoblastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stages I and II
-
Jin M, Inoue S, Umemura T, Moriya J, Arakawa M, Nagashima K, et al. Cyclin D1, p16 and retinoblastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stages I and II. Lung Cancer 2001; 34:207-18.
-
(2001)
Lung Cancer
, vol.34
, pp. 207-218
-
-
Jin, M.1
Inoue, S.2
Umemura, T.3
Moriya, J.4
Arakawa, M.5
Nagashima, K.6
-
82
-
-
0029011539
-
5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers
-
Merlo A, Herman JG, Mao L, Lee DJ, Gabrielson E, Burger PC, et al. 5′ CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nat Med 1995; 1:686-92.
-
(1995)
Nat Med
, vol.1
, pp. 686-692
-
-
Merlo, A.1
Herman, J.G.2
Mao, L.3
Lee, D.J.4
Gabrielson, E.5
Burger, P.C.6
-
83
-
-
0029849620
-
Cancer Cell Cycles
-
Sherr CJ. Cancer Cell Cycles. Science 1996; 274:1672-7.
-
(1996)
Science
, vol.274
, pp. 1672-1677
-
-
Sherr, C.J.1
-
84
-
-
0141730293
-
Cyclin D1 gene (CCND1) mutations in endometrial cancer
-
Moreno-Bueno G, Rodriguez-Perales S, Sanchez-Estevez C, Hardisson D, Sarrio D, Prat J, et al. Cyclin D1 gene (CCND1) mutations in endometrial cancer. Oncogene 2003; 22:6115-8.
-
(2003)
Oncogene
, vol.22
, pp. 6115-6118
-
-
Moreno-Bueno, G.1
Rodriguez-Perales, S.2
Sanchez-Estevez, C.3
Hardisson, D.4
Sarrio, D.5
Prat, J.6
-
85
-
-
11244264657
-
C-terminal sequences direct cyclin D1-CRM1 binding
-
Benzeno S, Diehl JA. C-terminal sequences direct cyclin D1-CRM1 binding. J Biol Chem 2004; 279:56061-6.
-
(2004)
J Biol Chem
, vol.279
, pp. 56061-56066
-
-
Benzeno, S.1
Diehl, J.A.2
-
86
-
-
52649093874
-
Speeding through cell cycle roadblocks: Nuclear cyclin D1-dependent kinase and neoplastic transformation
-
Pontano LL, Diehl JA. Speeding through cell cycle roadblocks: Nuclear cyclin D1-dependent kinase and neoplastic transformation. Cell Div 2008; 3:12.
-
(2008)
Cell Div
, vol.3
, pp. 12
-
-
Pontano, L.L.1
Diehl, J.A.2
-
87
-
-
0033007272
-
Folate and carcinogenesis: Evidence, mechanisms and implications
-
Kim YI. Folate and carcinogenesis: evidence, mechanisms and implications. J Nutr Biochem 1999; 10:66-88.
-
(1999)
J Nutr Biochem
, vol.10
, pp. 66-88
-
-
Kim, Y.I.1
-
88
-
-
0037093272
-
Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia
-
Skibola CF, Smith MT, Hubbard A, Shane B, Roberts AC, Law GR, et al. Polymorphisms in the thymidylate synthase and serine hydroxymethyltransferase genes and risk of adult acute lymphocytic leukemia. Blood 2002; 99:3786-91.
-
(2002)
Blood
, vol.99
, pp. 3786-3791
-
-
Skibola, C.F.1
Smith, M.T.2
Hubbard, A.3
Shane, B.4
Roberts, A.C.5
Law, G.R.6
-
89
-
-
0035906343
-
DNA damage from micronutrient deficiencies is likely to be a major cause of cancer
-
Ames BN. DNA damage from micronutrient deficiencies is likely to be a major cause of cancer. Mutat Res 2001; 475:7-20.
-
(2001)
Mutat Res
, vol.475
, pp. 7-20
-
-
Ames, B.N.1
-
90
-
-
4143137597
-
Causes of childhood leukaemia and lymphoma
-
Lightfoot TJ, Roman E. Causes of childhood leukaemia and lymphoma. Toxicol Appl Pharmacol 2004; 199:104-17.
-
(2004)
Toxicol Appl Pharmacol
, vol.199
, pp. 104-117
-
-
Lightfoot, T.J.1
Roman, E.2
-
91
-
-
29144473036
-
-
Bilousova G, Marusyk A, Porter CC, Cardiff RD, DeGregori J. Impaired DNA replication within progenitor cell pools promotes leukemogenesis. PLoS Biol 2005; 3:401.
-
Bilousova G, Marusyk A, Porter CC, Cardiff RD, DeGregori J. Impaired DNA replication within progenitor cell pools promotes leukemogenesis. PLoS Biol 2005; 3:401.
-
-
-
-
92
-
-
0035824574
-
The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor
-
Klingler-Hoffmann M, Fodero-Tavoletti MT, Mishima K, Narita Y, Cavenee WK, Furnari FB, et al. The protein tyrosine phosphatase TCPTP suppresses the tumorigenicity of glioblastoma cells expressing a mutant epidermal growth factor receptor. J Biol Chem 2001; 276:46313-8.
-
(2001)
J Biol Chem
, vol.276
, pp. 46313-46318
-
-
Klingler-Hoffmann, M.1
Fodero-Tavoletti, M.T.2
Mishima, K.3
Narita, Y.4
Cavenee, W.K.5
Furnari, F.B.6
-
93
-
-
7944236605
-
A novel mechanism for imatinib mesylate (STI571) resistance in CML cell line KT-1: Role of TC-PTP in modulating signals downstream from the BCR-ABL fusion protein
-
Shimizu T, Miyakawa Y, Iwata S, Kuribara A, Tiganis T, Morimoto C, et al. A novel mechanism for imatinib mesylate (STI571) resistance in CML cell line KT-1: role of TC-PTP in modulating signals downstream from the BCR-ABL fusion protein. Exp Hematol 2004; 32:1057-63.
-
(2004)
Exp Hematol
, vol.32
, pp. 1057-1063
-
-
Shimizu, T.1
Miyakawa, Y.2
Iwata, S.3
Kuribara, A.4
Tiganis, T.5
Morimoto, C.6
-
94
-
-
33947221062
-
T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6
-
Lu X, Chen J, Sasmono RT, Hsi ED, Sarosiek KA, Tiganis T, et al. T-cell protein tyrosine phosphatase, distinctively expressed in activated-B-cell-like diffuse large B-cell lymphomas, is the nuclear phosphatase of STAT6. Mol Cell Biol 2007; 27:2166-79.
-
(2007)
Mol Cell Biol
, vol.27
, pp. 2166-2179
-
-
Lu, X.1
Chen, J.2
Sasmono, R.T.3
Hsi, E.D.4
Sarosiek, K.A.5
Tiganis, T.6
-
95
-
-
25144514393
-
CDKs give Cdc6 a license to drive into S phase
-
Ayad NG. CDKs give Cdc6 a license to drive into S phase. Cell 2005; 122:825-7.
-
(2005)
Cell
, vol.122
, pp. 825-827
-
-
Ayad, N.G.1
-
96
-
-
25144525540
-
CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis
-
Mailand N, Diffley JF. CDKs promote DNA replication origin licensing in human cells by protecting Cdc6 from APC/C-dependent proteolysis. Cell 2005; 122:915-26.
-
(2005)
Cell
, vol.122
, pp. 915-926
-
-
Mailand, N.1
Diffley, J.F.2
-
97
-
-
58149234010
-
Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly
-
Braden WA, McClendon AK, Knudsen ES. Cyclin-dependent kinase 4/6 activity is a critical determinant of pre-replication complex assembly. Oncogene 2008.
-
(2008)
Oncogene
-
-
Braden, W.A.1
McClendon, A.K.2
Knudsen, E.S.3
-
98
-
-
0027220020
-
CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae
-
Schwob E, Nasmyth K. CLB5 and CLB6, a new pair of B cyclins involved in DNA replication in Saccharomyces cerevisiae. Genes Dev 1993; 7:1160-75.
-
(1993)
Genes Dev
, vol.7
, pp. 1160-1175
-
-
Schwob, E.1
Nasmyth, K.2
-
99
-
-
0026699308
-
CLB5: A novel B cyclin from budding yeast with a role in S phase
-
Epstein CB, Cross FR. CLB5: a novel B cyclin from budding yeast with a role in S phase. Genes Dev 1992; 6:1695-706.
-
(1992)
Genes Dev
, vol.6
, pp. 1695-1706
-
-
Epstein, C.B.1
Cross, F.R.2
-
100
-
-
0032134456
-
CLB5-dependent activation of late replication origins in S. cerevisiae
-
Donaldson AD, Raghuraman MK, Friedman KL, Cross FR, Brewer BJ, Fangman WL. CLB5-dependent activation of late replication origins in S. cerevisiae. Mol Cell 1998; 2:173-82.
-
(1998)
Mol Cell
, vol.2
, pp. 173-182
-
-
Donaldson, A.D.1
Raghuraman, M.K.2
Friedman, K.L.3
Cross, F.R.4
Brewer, B.J.5
Fangman, W.L.6
-
101
-
-
33846328709
-
Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast
-
Zegerman P, Diffley JF. Phosphorylation of Sld2 and Sld3 by cyclin-dependent kinases promotes DNA replication in budding yeast. Nature 2007; 445:281-5.
-
(2007)
Nature
, vol.445
, pp. 281-285
-
-
Zegerman, P.1
Diffley, J.F.2
-
102
-
-
11844295386
-
Coordinated Regulation of Insulin Signaling by the Protein Tyrosine Phosphatases PTP1B and TCPTP
-
Galic S, Hauser C, Kahn BB, Haj FG, Neel BG, Tonks NK, et al. Coordinated Regulation of Insulin Signaling by the Protein Tyrosine Phosphatases PTP1B and TCPTP. Mol Cell Biol 2005; 25:819-29.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 819-829
-
-
Galic, S.1
Hauser, C.2
Kahn, B.B.3
Haj, F.G.4
Neel, B.G.5
Tonks, N.K.6
|