An unusual helix turn helix motif in the catalytic core of HIV-1 integrase binds viral DNA and LGDGF

PLoS ONE

Volumn 4, Issue 1, 2009, Pages

  Merad, Hayate ^a   Porumb, Horea ^a   Zargarian, Loussiné ^a   Reé, Brigitte ^a   Hobaika, Zeina ^a   Maroun, Richard G ^b   Mauffret, Oliver ^a   Fermandjian, Serge ^a  

^a Ecole Normale Superieure de Cachan   (France)

^b SAINT JOSEPH UNIVERSITY   (Lebanon)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARAGINE; ASPARTIC ACID; INTEGRASE; LENS EPITHELIUM DERIVED GROWTH FACTOR; VIRUS DNA; HELIX LOOP HELIX PROTEIN; LENS EPITHELIUM-DERIVED GROWTH FACTOR; OLIGONUCLEOTIDE; PEPTIDE; SIGNAL PEPTIDE;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DNA BINDING; DNA BINDING MOTIF; DNA CONFORMATION; DNA HELIX; ENZYME ACTIVITY; ENZYME BINDING; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; MOLECULAR INTERACTION; NONHUMAN; OLIGOMERIZATION; VIRUS CORE; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; HUMAN; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

AMINO ACID SEQUENCE; DNA, VIRAL; HELIX-TURN-HELIX MOTIFS; HIV INTEGRASE; HIV-1; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; OLIGONUCLEOTIDES; PEPTIDES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

EID: 58149474162     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0004081     Document Type: Article

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