-
1
-
-
0038529679
-
Pharmacological profiles of peptide drug candidates for the treatment of Alzheimer's disease
-
Adessi C., Frossard M.J., Boissard C., Fraga S., Bieler S., Ruckle T., Vilbois F., Robinson S.M., Mutter M., Banks W.A., and Soto C. Pharmacological profiles of peptide drug candidates for the treatment of Alzheimer's disease. The Journal of Biological Chemistry 278 16 (2003) 13905-13911
-
(2003)
The Journal of Biological Chemistry
, vol.278
, Issue.16
, pp. 13905-13911
-
-
Adessi, C.1
Frossard, M.J.2
Boissard, C.3
Fraga, S.4
Bieler, S.5
Ruckle, T.6
Vilbois, F.7
Robinson, S.M.8
Mutter, M.9
Banks, W.A.10
Soto, C.11
-
2
-
-
58149192688
-
Delivery of peptides to the brain: emphasis on therapeutic development
-
10.1002/journal.bip.20980
-
Banks W.A. Delivery of peptides to the brain: emphasis on therapeutic development. Biopolymers 90 5 (2008) 589-594 10.1002/journal.bip.20980
-
(2008)
Biopolymers
, vol.90
, Issue.5
, pp. 589-594
-
-
Banks, W.A.1
-
3
-
-
0035896584
-
A novel family of phosphatidylinositol 4-kinases conserved from yeast to humans
-
Barylko B., Gerber S.H., Binns D.D., Grichine N., Khvotchev M., Südhof T.C., and Albanesi J.P. A novel family of phosphatidylinositol 4-kinases conserved from yeast to humans. The Journal of Biological Chemistry 276 11 (2001) 7705-7708
-
(2001)
The Journal of Biological Chemistry
, vol.276
, Issue.11
, pp. 7705-7708
-
-
Barylko, B.1
Gerber, S.H.2
Binns, D.D.3
Grichine, N.4
Khvotchev, M.5
Südhof, T.C.6
Albanesi, J.P.7
-
4
-
-
50849116386
-
STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits
-
10.1093/journal.brain/ awn125
-
Cancino G.I., Toledo E.M., Leal N.R., Hernandez D.E., Yévenes L.F., Inestrosa N.C., and Alvarez A.R. STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's β-amyloid deposits. Brain 131 9 (2008) 2425-2442 10.1093/journal.brain/ awn125
-
(2008)
Brain
, vol.131
, Issue.9
, pp. 2425-2442
-
-
Cancino, G.I.1
Toledo, E.M.2
Leal, N.R.3
Hernandez, D.E.4
Yévenes, L.F.5
Inestrosa, N.C.6
Alvarez, A.R.7
-
5
-
-
13844298651
-
Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms
-
Cheung E.C., Melanson-Drapeau L., Cregan S.P., Vanderluit J.L., Ferguson K.L., McIntosh W.C., Park D.S., Bennett S.A., and Slack R.S. Apoptosis-inducing factor is a key factor in neuronal cell death propagated by BAX-dependent and BAX-independent mechanisms. The Journal of Neuroscience 25 6 (2005) 1324-1334
-
(2005)
The Journal of Neuroscience
, vol.25
, Issue.6
, pp. 1324-1334
-
-
Cheung, E.C.1
Melanson-Drapeau, L.2
Cregan, S.P.3
Vanderluit, J.L.4
Ferguson, K.L.5
McIntosh, W.C.6
Park, D.S.7
Bennett, S.A.8
Slack, R.S.9
-
6
-
-
34548453704
-
Amyloid β protein modulates glutamate-mediated neurotransmission in the rat basal forebrain: involvement of presynaptic neuronal nicotinic acetylcholine and metabotropic glutamate receptors
-
Chin J.H., Ma L., MacTavish D., and Jhamandas J.H. Amyloid β protein modulates glutamate-mediated neurotransmission in the rat basal forebrain: involvement of presynaptic neuronal nicotinic acetylcholine and metabotropic glutamate receptors. The Journal of Neuroscience 27 35 (2007) 9262-9269
-
(2007)
The Journal of Neuroscience
, vol.27
, Issue.35
, pp. 9262-9269
-
-
Chin, J.H.1
Ma, L.2
MacTavish, D.3
Jhamandas, J.H.4
-
7
-
-
34547878297
-
Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression
-
Esposito G., Scuderi C., Savani C., Steardo Jr. L., De Filippis D., Cottone P., Iuvone T., Cuomo V., and Steardo L. Cannabidiol in vivo blunts β-amyloid induced neuroinflammation by suppressing IL-1β and iNOS expression. British Journal of Pharmacology 151 8 (2007) 1272-1279
-
(2007)
British Journal of Pharmacology
, vol.151
, Issue.8
, pp. 1272-1279
-
-
Esposito, G.1
Scuderi, C.2
Savani, C.3
Steardo Jr., L.4
De Filippis, D.5
Cottone, P.6
Iuvone, T.7
Cuomo, V.8
Steardo, L.9
-
8
-
-
4744345414
-
β-amyloid-derived pentapeptide RIIGLa inhibits Aβ1-42 aggregation and toxicity
-
Fülöp L., Zarándi M., Datki Z., Soós K., and Penke B. β-amyloid-derived pentapeptide RIIGLa inhibits Aβ1-42 aggregation and toxicity. Biochemical and Biophysical Research Communications 324 1 (2004) 64-69
-
(2004)
Biochemical and Biophysical Research Communications
, vol.324
, Issue.1
, pp. 64-69
-
-
Fülöp, L.1
Zarándi, M.2
Datki, Z.3
Soós, K.4
Penke, B.5
-
9
-
-
0033519547
-
Propionyl-IIGL tetrapeptide antagonizes β-amyloid excitotoxicity in rat nucleus basalis
-
Harkany T., Ábrahám I., Laskay G., Timmerman W., Jost K., Zarándi M., Penke B., Nyakas C., and Luiten P.G. Propionyl-IIGL tetrapeptide antagonizes β-amyloid excitotoxicity in rat nucleus basalis. Neuroreport 10 8 (1999) 1693-1698
-
(1999)
Neuroreport
, vol.10
, Issue.8
, pp. 1693-1698
-
-
Harkany, T.1
Ábrahám, I.2
Laskay, G.3
Timmerman, W.4
Jost, K.5
Zarándi, M.6
Penke, B.7
Nyakas, C.8
Luiten, P.G.9
-
10
-
-
0036293083
-
Pentapeptide amides interfere with the aggregation of β-amyloid peptide of Alzheimer's disease
-
Hetényi C., Szabó Z., Klement E., Datki Z., Körtvélyesi T., Zarándi M., and Penke B. Pentapeptide amides interfere with the aggregation of β-amyloid peptide of Alzheimer's disease. Biochemical and Biophysical Research Communications 292 4 (2002) 931-936
-
(2002)
Biochemical and Biophysical Research Communications
, vol.292
, Issue.4
, pp. 931-936
-
-
Hetényi, C.1
Szabó, Z.2
Klement, E.3
Datki, Z.4
Körtvélyesi, T.5
Zarándi, M.6
Penke, B.7
-
11
-
-
0037821794
-
Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes
-
Hresko R.C., Murata H., and Mueckler M. Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes. The Journal of Biological Chemistry 278 24 (2003) 21615-21622
-
(2003)
The Journal of Biological Chemistry
, vol.278
, Issue.24
, pp. 21615-21622
-
-
Hresko, R.C.1
Murata, H.2
Mueckler, M.3
-
12
-
-
0034700471
-
Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease
-
Janus C., Pearson J., McLaurin J., Mathews P.M., Jiang Y., Schmidt S.D., Chishti M.A., Horne P., Heslin D., French J., Mount H.T., Nixon R.A., Mercken M., Bergeron C., Fraser P.E., St George-Hyslop P., and Westaway D. Aβ peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease. Nature 408 6815 (2000) 979-982
-
(2000)
Nature
, vol.408
, Issue.6815
, pp. 979-982
-
-
Janus, C.1
Pearson, J.2
McLaurin, J.3
Mathews, P.M.4
Jiang, Y.5
Schmidt, S.D.6
Chishti, M.A.7
Horne, P.8
Heslin, D.9
French, J.10
Mount, H.T.11
Nixon, R.A.12
Mercken, M.13
Bergeron, C.14
Fraser, P.E.15
St George-Hyslop, P.16
Westaway, D.17
-
13
-
-
33746885863
-
Potential lead for an Alzheimer drug: a peptide that blocks intermolecular interaction and amyloid β protein-induced cytotoxicity
-
Kwak J.W., Kim H.K., and Chae C.B. Potential lead for an Alzheimer drug: a peptide that blocks intermolecular interaction and amyloid β protein-induced cytotoxicity. Journal of Medicinal Chemistry 49 16 (2006) 4813-4817
-
(2006)
Journal of Medicinal Chemistry
, vol.49
, Issue.16
, pp. 4813-4817
-
-
Kwak, J.W.1
Kim, H.K.2
Chae, C.B.3
-
14
-
-
16244369428
-
Effects of Aβ1-42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the τ-protein and on the α7 nicotinic acetylcholine receptor in vitro
-
Lain E., Penke B., Delacourte A., Gündisch D., Schröder H., and Witter B. Effects of Aβ1-42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the τ-protein and on the α7 nicotinic acetylcholine receptor in vitro. European Journal of Neuroscience 21 4 (2005) 879-888
-
(2005)
European Journal of Neuroscience
, vol.21
, Issue.4
, pp. 879-888
-
-
Lain, E.1
Penke, B.2
Delacourte, A.3
Gündisch, D.4
Schröder, H.5
Witter, B.6
-
15
-
-
0031587956
-
2+]i in rat astrocytes
-
2+]i in rat astrocytes. Biochemical and Biophysical Research Communications 235 3 (1997) 479-481
-
(1997)
Biochemical and Biophysical Research Communications
, vol.235
, Issue.3
, pp. 479-481
-
-
Laskay, G.1
Zarándi, M.2
Varga, J.3
Jost, K.4
Fónagy, A.5
Torday, C.6
Latzkovits, L.7
Penke, B.8
-
16
-
-
0033231262
-
Neurodegenerative tauopathies: human disease and transgenic mouse models
-
Lee V.M., and Trojanowski J.Q. Neurodegenerative tauopathies: human disease and transgenic mouse models. Neuron 24 3 (1999) 507-510
-
(1999)
Neuron
, vol.24
, Issue.3
, pp. 507-510
-
-
Lee, V.M.1
Trojanowski, J.Q.2
-
17
-
-
0029665941
-
Activation of phospholipase A2 by amyloid β-peptides in vitro
-
Lehtonen J.Y., Holopainen J.M., and Kinnunen P.K. Activation of phospholipase A2 by amyloid β-peptides in vitro. Biochemistry 35 29 (1996) 9407-9414
-
(1996)
Biochemistry
, vol.35
, Issue.29
, pp. 9407-9414
-
-
Lehtonen, J.Y.1
Holopainen, J.M.2
Kinnunen, P.K.3
-
18
-
-
27644540190
-
Effect of amyloid peptides on the increase in TrkA receptor expression induced by nicotine in vitro and in vivo
-
Li X.D., Arias E., Jonnala R.R., Mruthinti S., and Buccafusco J.J. Effect of amyloid peptides on the increase in TrkA receptor expression induced by nicotine in vitro and in vivo. Journal of Molecular Neuroscience 27 3 (2005) 325-336
-
(2005)
Journal of Molecular Neuroscience
, vol.27
, Issue.3
, pp. 325-336
-
-
Li, X.D.1
Arias, E.2
Jonnala, R.R.3
Mruthinti, S.4
Buccafusco, J.J.5
-
19
-
-
0032066030
-
β-Amyloid(1-40)-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield
-
Miguel-Hidalgo J.J., and Cacabelos R. β-Amyloid(1-40)-induced neurodegeneration in the rat hippocampal neurons of the CA1 subfield. Acta Neuropathologica (Berlin) 95 5 (1998) 455-465
-
(1998)
Acta Neuropathologica (Berlin)
, vol.95
, Issue.5
, pp. 455-465
-
-
Miguel-Hidalgo, J.J.1
Cacabelos, R.2
-
20
-
-
34247254916
-
Protection against Aβ-induced memory loss by tripeptide D-Arg-L-Glu-L-Arg
-
Mileusnic R., Lancashire C., Clark J., and Rose S.P. Protection against Aβ-induced memory loss by tripeptide D-Arg-L-Glu-L-Arg. Behavioural Pharmacology 18 3 (2007) 231-238
-
(2007)
Behavioural Pharmacology
, vol.18
, Issue.3
, pp. 231-238
-
-
Mileusnic, R.1
Lancashire, C.2
Clark, J.3
Rose, S.P.4
-
21
-
-
1842633450
-
The peptide sequence Arg-Glu-Arg, present in the amyloid precursor protein, protects against memory loss caused by Aβ and acts as a cognitive enhancer
-
Mileusnic R., Lancashire C.L., and Rose S.P. The peptide sequence Arg-Glu-Arg, present in the amyloid precursor protein, protects against memory loss caused by Aβ and acts as a cognitive enhancer. European Journal of Neuroscience 19 7 (2004) 1933-1938
-
(2004)
European Journal of Neuroscience
, vol.19
, Issue.7
, pp. 1933-1938
-
-
Mileusnic, R.1
Lancashire, C.L.2
Rose, S.P.3
-
22
-
-
38549141544
-
Amyloid β oligomers (Aβ1-42 globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents
-
Nimmrich V., Grimm C., Draguhn A., Barghorn S., Lehmann A., Schoemaker H., Hillen H., Gross G., Ebert U., and Bruehl C. Amyloid β oligomers (Aβ1-42 globulomer) suppress spontaneous synaptic activity by inhibition of P/Q-type calcium currents. The Journal of Neuroscience 28 4 (2008) 788-797
-
(2008)
The Journal of Neuroscience
, vol.28
, Issue.4
, pp. 788-797
-
-
Nimmrich, V.1
Grimm, C.2
Draguhn, A.3
Barghorn, S.4
Lehmann, A.5
Schoemaker, H.6
Hillen, H.7
Gross, G.8
Ebert, U.9
Bruehl, C.10
-
23
-
-
0031942410
-
Regional membrane phospholipid alterations in Alzheimer's disease
-
Prasad M.R., Lovell M.A., Yatin M., Dhillon H., and Markesbery W.R. Regional membrane phospholipid alterations in Alzheimer's disease. Neurochemical Research 23 1 (1998) 81-88
-
(1998)
Neurochemical Research
, vol.23
, Issue.1
, pp. 81-88
-
-
Prasad, M.R.1
Lovell, M.A.2
Yatin, M.3
Dhillon, H.4
Markesbery, W.R.5
-
24
-
-
6044273035
-
Minocycline inhibits neuronal death and glial activation induced by β-amyloid peptide in rat hippocampus
-
Ryu J.K., Franciosi S., Sattayaprasert P., Kim S.U., and McLarnon J.G. Minocycline inhibits neuronal death and glial activation induced by β-amyloid peptide in rat hippocampus. Glia 48 1 (2004) 85-90
-
(2004)
Glia
, vol.48
, Issue.1
, pp. 85-90
-
-
Ryu, J.K.1
Franciosi, S.2
Sattayaprasert, P.3
Kim, S.U.4
McLarnon, J.G.5
-
25
-
-
0035066332
-
Alzheimer's disease: genes, proteins, and therapy
-
Selkoe D.J. Alzheimer's disease: genes, proteins, and therapy. Physiological Reviews 81 2 (2001) 741-766
-
(2001)
Physiological Reviews
, vol.81
, Issue.2
, pp. 741-766
-
-
Selkoe, D.J.1
-
26
-
-
0037216458
-
Effects of tumor necrosis factor-alpha central administration on hippocampal damage in rat induced by amyloid β-peptide (25-35)
-
Stepanichev M.Y., Zdobnova I.M., Yakovlev A.A., Onufriev M.V., Lazareva N.A., Zarubenko I.I., and Gulyaeva N.V. Effects of tumor necrosis factor-alpha central administration on hippocampal damage in rat induced by amyloid β-peptide (25-35). Journal of Neuroscience Research 71 1 (2003) 110-120
-
(2003)
Journal of Neuroscience Research
, vol.71
, Issue.1
, pp. 110-120
-
-
Stepanichev, M.Y.1
Zdobnova, I.M.2
Yakovlev, A.A.3
Onufriev, M.V.4
Lazareva, N.A.5
Zarubenko, I.I.6
Gulyaeva, N.V.7
-
27
-
-
0035664048
-
Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau
-
Tanemura K., Akagi T., Murayama M., Kikuchi N., Murayama O., Hashikawa T., Yoshiike Y., Park J.M., Matsuda K., Nakao S., Sun X., Sato S., Yamaguchi H., and Takashima A. Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau. Neurobiology of Disease 8 6 (2001) 1036-1045
-
(2001)
Neurobiology of Disease
, vol.8
, Issue.6
, pp. 1036-1045
-
-
Tanemura, K.1
Akagi, T.2
Murayama, M.3
Kikuchi, N.4
Murayama, O.5
Hashikawa, T.6
Yoshiike, Y.7
Park, J.M.8
Matsuda, K.9
Nakao, S.10
Sun, X.11
Sato, S.12
Yamaguchi, H.13
Takashima, A.14
-
28
-
-
0036138044
-
Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau
-
Tanemura K., Murayama M., Akagi T., Hashikawa T., Tominaga T., Ichikawa M., Yamaguchi H., and Takashima A. Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau. The Journal of Neuroscience 22 1 (2002) 133-141
-
(2002)
The Journal of Neuroscience
, vol.22
, Issue.1
, pp. 133-141
-
-
Tanemura, K.1
Murayama, M.2
Akagi, T.3
Hashikawa, T.4
Tominaga, T.5
Ichikawa, M.6
Yamaguchi, H.7
Takashima, A.8
-
29
-
-
23044468691
-
The synaptic Aβ hypothesis of Alzheimer disease
-
Tanzi R.E. The synaptic Aβ hypothesis of Alzheimer disease. Nature Neuroscience 8 8 (2005) 977-979
-
(2005)
Nature Neuroscience
, vol.8
, Issue.8
, pp. 977-979
-
-
Tanzi, R.E.1
-
31
-
-
33244487007
-
Attenuation of amyloid β (Aβ)-induced inhibition of phosphatidylinositol 4-kinase activity by Aβ fragments, Aβ20-29 and Aβ31-35
-
Wu B., Kitagawa K., Liu B., Zhang N.Y., Xiong Z.M., and Inagaki C. Attenuation of amyloid β (Aβ)-induced inhibition of phosphatidylinositol 4-kinase activity by Aβ fragments, Aβ20-29 and Aβ31-35. Neuroscience Letters 396 2 (2006) 148-152
-
(2006)
Neuroscience Letters
, vol.396
, Issue.2
, pp. 148-152
-
-
Wu, B.1
Kitagawa, K.2
Liu, B.3
Zhang, N.Y.4
Xiong, Z.M.5
Inagaki, C.6
-
33
-
-
9744225795
-
Pathophysiological concentrations of amyloid β proteins directly inhibit rat brain and recombinant human type II phosphatidylinositol 4-kinase activity
-
Wu B., Kitagawa K., Zhang N.Y., Liu B., and Inagaki C. Pathophysiological concentrations of amyloid β proteins directly inhibit rat brain and recombinant human type II phosphatidylinositol 4-kinase activity. Journal of Neurochemistry 91(5) (2004) 1164-1170
-
(2004)
Journal of Neurochemistry
, vol.91 5
, pp. 1164-1170
-
-
Wu, B.1
Kitagawa, K.2
Zhang, N.Y.3
Liu, B.4
Inagaki, C.5
-
34
-
-
34248529817
-
Protective effects of Aβ-derived tripeptide, Aβ32-34, on Aβ1-42-induced phosphatidylinositol 4-kinase inhibition and neurotoxicity
-
Xiong Z.M., Kitagawa K., Nishiuchi Y., Kimura T., and Inagaki C. Protective effects of Aβ-derived tripeptide, Aβ32-34, on Aβ1-42-induced phosphatidylinositol 4-kinase inhibition and neurotoxicity. Neuroscience Letters 419 3 (2007) 247-252
-
(2007)
Neuroscience Letters
, vol.419
, Issue.3
, pp. 247-252
-
-
Xiong, Z.M.1
Kitagawa, K.2
Nishiuchi, Y.3
Kimura, T.4
Inagaki, C.5
-
35
-
-
0034899730
-
-ATPase activity in cultured rat hippocampal neurons
-
-ATPase activity in cultured rat hippocampal neurons. Journal of Neurochemistry 78 3 (2001) 569-576
-
(2001)
Journal of Neurochemistry
, vol.78
, Issue.3
, pp. 569-576
-
-
Yagyu, K.1
Kitagawa, K.2
Irie, T.3
Wu, B.4
Zeng, X.T.5
Hattori, N.6
Inagaki, C.7
-
36
-
-
34247174949
-
Soybean-derived phosphatidylinositol inhibits in vivo low concentrations of amyloid β protein-induced degeneration of hippocampal neurons in V337M human tau-expressing mice
-
Zhang N.Y., Kitagawa K., Hattori N., Nakayama Y., Xiong Z.M., Wu B., Liu B., and Inagaki C. Soybean-derived phosphatidylinositol inhibits in vivo low concentrations of amyloid β protein-induced degeneration of hippocampal neurons in V337M human tau-expressing mice. Life Sciences 80 21 (2007) 1971-1976
-
(2007)
Life Sciences
, vol.80
, Issue.21
, pp. 1971-1976
-
-
Zhang, N.Y.1
Kitagawa, K.2
Hattori, N.3
Nakayama, Y.4
Xiong, Z.M.5
Wu, B.6
Liu, B.7
Inagaki, C.8
-
37
-
-
0042326217
-
Soybean-derived phosphatidylinositol recovers amyloid β protein-induced neurotoxicity in cultured rat hippocampal neurons
-
Zhang N.Y., Kitagawa K., Wu B., and Inagaki C. Soybean-derived phosphatidylinositol recovers amyloid β protein-induced neurotoxicity in cultured rat hippocampal neurons. Neuroscience Letters 350 2 (2003) 105-108
-
(2003)
Neuroscience Letters
, vol.350
, Issue.2
, pp. 105-108
-
-
Zhang, N.Y.1
Kitagawa, K.2
Wu, B.3
Inagaki, C.4
-
38
-
-
33646091744
-
Chloride-dependency of amyloid β protein-induced enhancement of glutamate neurotoxicity in cultured rat hippocampal neurons
-
Zhang N.Y., Kitagawa K., Wu B., Xiong Z.M., Otani H., and Inagaki C. Chloride-dependency of amyloid β protein-induced enhancement of glutamate neurotoxicity in cultured rat hippocampal neurons. Neuroscience Letters 399 1-2 (2006) 175-180
-
(2006)
Neuroscience Letters
, vol.399
, Issue.1-2
, pp. 175-180
-
-
Zhang, N.Y.1
Kitagawa, K.2
Wu, B.3
Xiong, Z.M.4
Otani, H.5
Inagaki, C.6
|