Protective effects of Aβ-derived tripeptide, Aβ32-34, on Aβ1-42-induced phosphatidylinositol 4-kinase inhibition and neurotoxicity

Neuroscience Letters

Volumn 419, Issue 3, 2007, Pages 247-252

  Xiong, Zheng Mei ^a,c   Kitagawa, Kaori ^a   Nishiuchi, Yuji ^b   Kimura, Terutoshi ^b   Inagaki, Chiyoko ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

^b Peptide Institute Inc   (Japan)

^c GUIZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Amyloid protein; Glutamate toxicity; Tripeptide (Ile Gly Leu); Type II phosphatidylinositol 4 kinase

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; AMYLOID BETA PROTEIN[31-33]; AMYLOID BETA PROTEIN[31-34]; AMYLOID BETA PROTEIN[31-35]; AMYLOID BETA PROTEIN[32-33]; AMYLOID BETA PROTEIN[32-34]; AMYLOID BETA PROTEIN[32-35]; AMYLOID BETA PROTEIN[33-34]; AMYLOID BETA PROTEIN[33-35]; AMYLOID BETA PROTEIN[34-35]; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG; NEUROPROTECTIVE AGENT; PEPTIDE FRAGMENT; PHOSPHATIDYLINOSITOL KINASE; RECOMBINANT PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; EMBRYO; ENZYME INHIBITION; GENETIC TRANSFECTION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; RAT; AMINO ACID SEQUENCE; ANIMAL; CELL CULTURE; HUMAN; METABOLISM; NERVE CELL; WISTAR RAT;

1-PHOSPHATIDYLINOSITOL 4-KINASE; AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ANIMALS; CELLS, CULTURED; HUMANS; NEURONS; NEUROPROTECTIVE AGENTS; PEPTIDE FRAGMENTS; RATS; RATS, WISTAR; RECOMBINANT PROTEINS;

EID: 34248529817     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2007.04.022     Document Type: Article

References (25)

1. Andrews W.V., and Conn P.M. Measurement of inositol phospholipids metabolites by one-dimensional thin-layer chromatography. Methods Enzymol. 141 (1987) 156-168
2. Balla A., and Balla T. Phosphatidylinositol 4-kinases: old enzymes with emerging functions. Trends Cell Biol. 16 (2006) 351-361
3. Barylko B., Gerber S.H., Binns D.D., Grichine N., Khvotchev M., Südhof T.C., and Albanesi J.P. A novel family of phosphatidylinositol 4-kinases conserved from yeast to humans. J. Biol. Chem. 276 (2001) 7705-7708
4. Bothmer J., Markerink M., and Jolles J. Phosphoinositide kinase activities in synaptosomes prepared from brains of patients with Alzheimer's disease and controls. Neurosci. Lett. 176 (1994) 169-172
5. Clementi M.E., Marini S., Coletta M., Orsini F., Giardina B., and Misiti F. Aβ(31-35) and Aβ(25-35) fragments of amyloid beta-protein induce cellular death through apoptotic signals: role of the redox state of methionine-35. FEBS Lett. 579 (2005) 2913-2918
6. 1-42 aggregation and toxicity. Biochem. Biophys. Res. Commun. 324 (2004) 64-69
7. Golde T.E. Disease modifying therapy for AD?. J. Neurochem. 99 (2006) 689-707
8. Harkany T., Ábrahám I., Laskay G., Timmerman W., Jost K., Zarándi M., Penke B., Nyakas C., and Luiten P.G. Propionyl-IIGL tetrapeptide antagonizes β-amyloid excitotoxicity in rat nucleus basalis. Neuroreport 10 (1999) 1693-1698
9. Hiruma H., Katakura T., Takahashi S., Ichikawa T., and Kawakami T. Glutamate and amyloid β-protein rapidly inhibit fast axonal transport in cultured rat hippocampal neurons by different mechanisms. J. Neurosci. 23 (2003) 8967-8977
10. Inui T., Bódi J., Nishio H., Nishiuchi Y., and Kimura T. Synthesis of amyloid β-peptides in solution employing chloroform-phenol mixed solvent for facile segment condensation of sparingly soluble protected peptides. Lett. Pept. Sci. 8 (2001) 319-330
11. Ivins K.J., Ivins J.K., Sharp J.P., and Cotman C.W. Multiple pathways of apoptosis in PC12 cells. J. Biol. Chem. 274 (1999) 2107-2112
12. 1-42 fibrils and of the tetrapeptide Pr-IIGL on the phosphorylation state of the τ-protein and on the α7 nicotinic acetylcholine receptor in vitro. Eur. J. Neurosci. 21 (2005) 879-888
13. i in rat astrocytes. Biochem. Biophys. Res. Commun. 235 (1997) 479-481
14. Misiti F., Clementi M.E., Tringali G., Vairano M., Orsini F., Pezzotti M., Navarra P., Giardina B., and Pozzoli G. Fragment 31-35 of β-amyloid peptide induces neurodegeneration in rat cerebellar granule cells via bax gene expression and caspase-3 activation. A crucial role for the redox state of methionine-35 residue. Neurochem. Int. 49 (2006) 525-532
15. Misiti F., Sampaolese B., Pezzotti M., Marini S., Coletta M., Ceccarelli L., Giardina B., and Clementi M.E. Aβ(31-35) peptide induce apoptosis in PC 12 cells: contrast with Aβ(25-35) peptide and examination of underlying mechanisms. Neurochem. Int. 46 (2005) 575-583
16. Pettegrew J.W., Panchalingam K., Hamilton R.L., and McClure R.J. Brain membrane phospholipid alterations in Alzheimer's disease. Neurochem. Res. 26 (2001) 771-782
17. Prasad M.R., Lovell M.A., Yatin M., Dhillon H., Dhillon H., and Markesbery W.R. Regional membrane phospholipid alterations in Alzheimer's disease. Neurochem. Res. 23 (1998) 81-88
18. Troy C.M., Rabacchi S.A., Xu Z.H., Maroney A.C., Connors T.J., Shelanski M.L., and Greene L.A. β-Amyloid-induced neuronal apoptosis requires c-Jun N-terminal kinase activation. J. Neurochem. 77 (2001) 157-164
19. Wallace M.A. Effects of Alzheimer's disease-related beta amyloid protein fragments on enzymes metabolizing phosphoinositides in brain. Biochim. Biophys. Acta 1227 (1994) 183-187
20. Wu B., Kitagawa K., Zhang N.Y., Liu B., and Inagaki C. Pathophysiological concentrations of amyloid β proteins directly inhibit rat brain and recombinant human type II phosphatidylinositol 4-kinase activity. J. Neurochem. 91 (2004) 1164-1170
21. Wu B., Kitagawa K., Liu B., Zhang N.Y., Xiong Z.M., and Inagaki C. Attenuation of amyloid β (Aβ)-induced inhibition of phosphatidylinositol 4-kinase activity by Aβ fragments, Aβ20-29 and Aβ31-35. Neurosci. Lett. 396 (2006) 148-152
22. --ATPase activity in cultured rat hippocampal neurons. J. Neurochem. 78 (2001) 569-576
23. --ATPase activity. Neuropharmacology 43 (2002) 1297-1304
24. Ye L., and Qiao J.T. Suppressive action produced by β-amyloid peptide fragment 31-35 on long-term potentiation in rat hippocampus is N-methyl-d-aspartate receptor-independent: it's offset by (-)huperzine A. Neurosci. Lett. 275 (1999) 187-190
25. Zhang N.Y., Kitagawa K., Wu B., Xiong Z.M., and Inagaki C. Chloride-dependency of amyloid β protein-induced enhancement of glutamate neurotoxicity in cultured rat hippocampal neurons. Neurosci. Lett. 399 (2006) 175-180