Chloride-dependency of amyloid β protein-induced enhancement of glutamate neurotoxicity in cultured rat hippocampal neurons

Neuroscience Letters

Volumn 399, Issue 1-2, 2006, Pages 175-180

  Zhang, Nan Yan ^a   Kitagawa, Kaori ^a   Wu, Bo ^a   Xiong, Zheng Mei ^a   Otani, Hitomi ^a   Inagaki, Chiyoko ^a  

^a KANSAI MEDICAL UNIVERSITY   (Japan)

Author keywords

Akt; Alzheimer disease; Amyloid protein; Glutamate; Intracellular Cl concentration

Indexed keywords

AMYLOID BETA PROTEIN; CHLORIDE; FLUORESCENT DYE; GLUTAMIC ACID; ISETHIONIC ACID; LACTATE DEHYDROGENASE; PROTEIN KINASE B; TYROSINE;

ANIMAL CELL; APOPTOSIS; ARTICLE; BRAIN NERVE CELL; CONTROLLED STUDY; CULTURE MEDIUM; EMBRYO; ENZYME ACTIVITY; HIPPOCAMPUS; MITOCHONDRION; NERVE CELL CULTURE; NEUROTOXICITY; NONHUMAN; OBSERVATION; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION; STATISTICAL SIGNIFICANCE; WESTERN BLOTTING;

1-PHOSPHATIDYLINOSITOL 3-KINASE; AMYLOID BETA-PROTEIN; ANIMALS; APOPTOSIS; CELLS, CULTURED; CHLORIDES; EMBRYO; GLUTAMIC ACID; HIPPOCAMPUS; INTRACELLULAR SPACE; L-LACTATE DEHYDROGENASE; MITOCHONDRIA; NEURONS; PEPTIDE FRAGMENTS; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RATS; RATS, WISTAR; TYROSINE;

EID: 33646091744     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2006.01.055     Document Type: Article

References (24)

1. - and inhibitory transmitters. Mol. Pharmacol. 53 (1998) 564-572
2. Crossthwaite A.J., Valli H., and Williams R.J. Inhibiting Src family tyrosine kinase activity blocks glutamate signalling to ERK1/2 and Akt/PKB but not JNK in cultured striatal neurones. J. Neurochem. 88 (2004) 1127-1139
3. Dessi F., Charriaut-Marlangue C., and Ben-Ari Y. Glutamate-induced neuronal death in cerebellar culture is mediated by two distinct components: a sodium-chloride component and a calcium component. Brain Res. 650 (1994) 49-55
4. Doble A. The role of excitotoxicity in neurodegenerative disease: implications for therapy. Pharmacol. Ther. 81 (1999) 163-221
5. Glaum S.R., and Miller R.J. Inhibition of phosphoprotein phosphatases blocks metabotropic glutamate receptor effects in the rat nucleus tractus solitarii. Mol. Pharmacol. 45 (1994) 1221-1226
6. - in rat hippocampal neurons. Neurosci. Lett. 143 (1992) 135-138
7. Hresko R.C., Murata H., and Mueckler M. Phosphoinositide-dependent kinase-2 is a distinct protein kinase enriched in a novel cytoskeletal fraction associated with adipocyte plasma membranes. J. Biol. Chem. 278 (2003) 21615-21622
8. Huang C.-C., Liang Y.-C., and Hsu K.-S. Characterization of the mechanism underlying the reversal of long term potentiation by low frequency stimulation at hippocampal CA1 synapses. J. Biol. Chem. 276 (2001) 48108-48117
9. Ivaska J., Nissinen L., Immonen N., Eriksson J.E., Kähäri V.-M., and Heino J. Integrin α2β1 promotes activation of protein phosphatase 2A and dephosphorylation of Akt and glycogen synthase kinase 3β. Mol. Cell. Biol. 22 (2002) 1352-1359
10. Kihara T., Shimohama S., Sawada H., Honda K., Nakamizo T., Shibasaki H., Kume T., and Akaike A. α7 nicotinic receptor transduces signals to phosphatidylinositol 3-kinase to block a β-amyloid-induced neurotoxicity. J. Biol. Chem. 276 (2001) 13541-13546
11. Ma J., Zhang G.-Y., Liu Y., Yan J.-Z., and Hao Z.-B. Lithium suppressed Tyr-402 phosphorylation of proline-rich tyrosine kinase (Pyk2) and interactions of Pyk2 and PSD-95 with NR2A in rat hippocampus following cerebral ischemia. Neurosci. Res. 49 (2004) 357-362
12. Osaki M., Oshimura M., and Ito H. PI3K-Akt pathway: its functions and alterations in human cancer. Apoptosis 9 (2004) 667-676
13. Peyclit A., Keita H., Juvin P., Derkinderen P., Jardinaud F., Rouelle D., Boczkowski J., Desmonts J.-M., Girault J.-A., and Mantz J. Effects of riluzole on N-methyl-d-aspartate-induced tyrosine phosphorylation in the rat hippocampus. Brain Res. 903 (2001) 222-225
14. Rothman S.M. The neurotoxicity of excitatory amino acids is produced by passive chloride influx. J. Neurosci. 5 (1985) 1483-1489
15. Siciliano J.C., Gelman M., and Girault J.-A. Depolarization and neurotransmitters increase neuronal protein tyrosine phosphorylation. J. Neurochem. 62 (1994) 950-959
16. FAK by glutamate and depolarization in rat hippocampus. J. Biol. Chem. 271 (1996) 28942-28946
17. Ugi S., Imamura T., Maegawa H., Egawa K., Yoshizaki T., Shi K., Obata T., Ebina Y., Kashiwagi A., and Olefshy J.M. Protein phosphatase 2A negatively regulates insulin's metabolic signaling pathway by inhibiting Akt (protein kinase B) activity in 3T3-L1 adipocytes. Mol. Cell. Biol. 24 (2004) 8778-8789
18. --ATPase activity. Life Sci. 72 (2002) 455-463
19. Xu W., Yuan X., Jung Y.J., Yang Y., Basso A., Rosen N., Chung E.J., Trepel J., and Neckers L. The heat shock protein 90 inhibitor geldanamycin and the ErbB inhibitor ZD1839 promote rapid PP1 phosphatase-dependent inactivation of AKT in ErbB2 overexpressing breast cancer cells. Cancer Res. 63 (2003) 7777-7784
20. --ATPase activity in cultured rat hippocampal neurons. J. Neurochem. 78 (2001) 569-576
21. --ATPase activity. Neuropharmacology 43 (2002) 1297-1304
22. Yang L., Omori K., Omori K., Otani H., Suzukawa J., and Inagaki C. GABAc receptor agonist suppressed ammonia-induced apoptosis in cultured rat hippocampal neurons by restoring phosphorylated BAD level. J. Neurochem. 87 (2003) 791-800
23. Zeevalk G.D., Hyndman A.G., and Nicklas W.J. Excitatory amino acid-induced toxicity in chick retina: amino acid release, histology, and effects of chloride channel blockers. J. Neurochem. 53 (1989) 1610-1619
24. Zhang N.-Y., Kitagawa K., Wu B., and Inagaki C. Soybean-derived phosphatidylinositol recovers amyloid β protein-induced neurotoxicity in cultured rat hippocampal neurons. Neurosci. Lett. 350 (2003) 105-108