Chk2 oligomerization studied by phosphopeptide ligation: Implications for regulation and phosphodependent interactions

Journal of Biological Chemistry

Volumn 283, Issue 51, 2008, Pages 36019-36030

  Li, Jiejin ^a   Taylor, Ian A ^a   Lloyd, Janette ^a   Clapperton, Julie A ^a   Howell, Steven ^a   MacMillan, Derek ^b   Smerdon, Stephen J ^a  

^a NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ASSOCIATION REACTIONS; CHEMICAL REACTIONS; FLOW INTERACTIONS; FLUID DYNAMICS; LAWS AND LEGISLATION; NUCLEIC ACIDS; OLIGOMERIZATION; ORGANIC ACIDS;

ATAXIA TELANGIECTASIAS; COMPLEX STRUCTURES; DIMER DISSOCIATIONS; DNA DAMAGE SIGNALS; DO-MAINS; EFFECTOR PROTEINS; EXPRESSED PROTEIN LIGATIONS; FHA DOMAINS; HIGH AFFINITIES; HYDRODYNAMIC ANALYSES; IN-VIVO; KINASE DOMAINS; PHOSPHOPEPTIDE; PRE-REQUISITES; REGULATORY REGIONS; THREONINE KINASES; TRANSDUCING;

PHOSPHORYLATION;

CHECKPOINT KINASE 2; THREONINE;

ARTICLE; AUTOPHOSPHORYLATION; BINDING AFFINITY; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVATION; ENZYME REGULATION; HYDRODYNAMICS; NONHUMAN; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; STOICHIOMETRY;

AMINO ACID MOTIFS; CELL CYCLE PROTEINS; DIMERIZATION; DNA DAMAGE; DNA-BINDING PROTEINS; ENZYME ACTIVATION; HUMANS; PHOSPHORYLATION; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 58149084898     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M804075200     Document Type: Article

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