Deficiency of TNFα converting enzyme (TACE/ADAM17) causes a lean, hypermetabolic phenotype in mice

Endocrinology

Volumn 149, Issue 12, 2008, Pages 6053-6064

  Gelling, Richard W ^a,d   Yan, Wenbo ^c   Al Noori, Salwa ^b   Pardini, Aaron ^a,e   Morton, Gregory J ^a   Ogimoto, Kayoko ^a   Schwartz, Michael W ^a   Dempsey, Peter J ^a,b,c  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

^b PACIFIC NORTHWEST RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF MICHIGAN   (United States)

^d Department of Metabolism   (United States)

^e Peace Health   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; ADAM PROTEIN; FAT; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN; TUMOR NECROSIS FACTOR-ALPHA CONVERTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BROWN ADIPOSE TISSUE; CONTROLLED STUDY; ENZYME ACTIVITY; HOMEOSTASIS; HYPERMETABOLISM; HYPOTHALAMUS; LEAN BODY WEIGHT; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; ADIPOCYTE; ANIMAL; ARCUATE NUCLEUS; BLOOD; BODY WEIGHT; CELL DIFFERENTIATION; CYTOLOGY; EATING; ENERGY METABOLISM; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; MOTOR ACTIVITY; MOUSE MUTANT; PATHOPHYSIOLOGY; PHYSIOLOGY; WESTERN BLOTTING;

ADAM PROTEINS; ADIPOCYTES; ANIMALS; ARCUATE NUCLEUS; BLOTTING, WESTERN; CELL DIFFERENTIATION; EATING; ENERGY METABOLISM; FATS; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; ION CHANNELS; LEPTIN; MALE; MICE; MICE, MUTANT STRAINS; MITOCHONDRIAL PROTEINS; MOTOR ACTIVITY; PHENOTYPE; THINNESS;

EID: 57349182490     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-0775     Document Type: Article

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