A novel missense mutation in the mouse growth hormone gene causes semidominant dwarfism, hyperghrelinemia, and obesity

Endocrinology

Volumn 145, Issue 5, 2004, Pages 2531-2541

  Meyer, Carola W E ^a   Korthaus, Dirk ^b   Jagla, Wolfgang ^b   Cornali, Emmanuelle ^b   Grosse, Johannes ^b   Fuchs, Helmut ^c   Klingenspor, Martin ^a   Roemheld, Stephanie ^a   Tschöp, Matthias ^d   Heldmaier, Gerhard ^a   De Angelis, Martin Hrabé ^c   Nehls, Michael ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b Ingenium Pharmaceuticals AG   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d UNIVERSITY OF CINCINNATI   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GHRELIN; GROWTH HORMONE;

ABNORMAL SUBSTRATE CONCENTRATION IN BLOOD; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DWARFISM; FERTILITY; GENE; GENE FUNCTION; GENOTYPE; HYPERGHRELINEMIA; MALE; MISSENSE MUTATION; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OBESITY; PRIORITY JOURNAL; SUBCUTANEOUS FAT; SURVIVAL; VISCERA;

ADIPOSE TISSUE; AMINO ACID SEQUENCE; ANIMALS; BODY COMPOSITION; BODY WEIGHT; DWARFISM; EXONS; FEMALE; FERTILITY; GENOTYPE; GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LINKAGE (GENETICS); MALE; MICE; MICE, INBRED C3H; MOLECULAR SEQUENCE DATA; MUTATION, MISSENSE; OBESITY; PEPTIDE HORMONES; PHENOTYPE; PITUITARY GLAND; SEQUENCE ALIGNMENT;

EID: 11144354485     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-1125     Document Type: Article

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