메뉴 건너뛰기




Volumn 167, Issue 4, 2004, Pages 1821-1832

Phenotypic variation resulting from a deficiency of epidermal growth factor receptor in mice is caused by extensive genetic heterogeneity that can be genetically and molecularly partitioned

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; MUTANT PROTEIN;

EID: 2942715388     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: 10.1534/genetics.103.020495     Document Type: Article
Times cited : (28)

References (40)
  • 1
    • 0030795612 scopus 로고    scopus 로고
    • The ErbB signaling network in embryogenesis and oncogenesis: Signal diversification through combinatorial ligand-receptor interactions
    • ALROY, I., and Y. YARDEN, 1997 The ErbB signaling network in embryogenesis and oncogenesis: signal diversification through combinatorial ligand-receptor interactions. FEBS Lett. 410: 83-86.
    • (1997) FEBS Lett. , vol.410 , pp. 83-86
    • Alroy, I.1    Yarden, Y.2
  • 2
    • 0038666476 scopus 로고    scopus 로고
    • Clinical trial design and end points for epidermal growth factor receptor-targeted therapies: Implications for drug development and practice
    • ARTEAGA, C. L., and J. BASELGA, 2003 Clinical trial design and end points for epidermal growth factor receptor-targeted therapies: implications for drug development and practice. Clin. Cancer Res. 9: 1579-1589.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 1579-1589
    • Arteaga, C.L.1    Baselga, J.2
  • 5
    • 0030825474 scopus 로고    scopus 로고
    • Increased basal expression of hepatic Cyp1a1 and Cyp1a2 genes in inbred mice selected for susceptibility to acetaminophen-induced hepatotoxicity
    • CASLEY, W. L., J. A. MENZIES, N. MOUSSEAU, M. GIRARD, T. W. MOON et al., 1997 Increased basal expression of hepatic Cyp1a1 and Cyp1a2 genes in inbred mice selected for susceptibility to acetaminophen-induced hepatotoxicity. Pharmacogenetics 7: 283-293.
    • (1997) Pharmacogenetics , vol.7 , pp. 283-293
    • Casley, W.L.1    Menzies, J.A.2    Mousseau, N.3    Girard, M.4    Moon, T.W.5
  • 6
    • 0025858250 scopus 로고
    • Differential expression of epidermal growth factor-related proteins in human colorectal tumors
    • CIARDIELLO, F., N. KIM, T. SAEKI, R. DONO, M. G. PERSICO et al., 1991 Differential expression of epidermal growth factor-related proteins in human colorectal tumors. Proc. Natl. Acad. Sci. USA 88: 7792-7796.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 7792-7796
    • Ciardiello, F.1    Kim, N.2    Saeki, T.3    Dono, R.4    Persico, M.G.5
  • 7
    • 84916265276 scopus 로고
    • Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal
    • COHEN, S., 1962 Isolation of a mouse submaxillary gland protein accelerating incisor eruption and eyelid opening in the new-born animal. J. Biol. Chem. 237: 1555-1562.
    • (1962) J. Biol. Chem. , vol.237 , pp. 1555-1562
    • Cohen, S.1
  • 8
    • 0015834590 scopus 로고
    • Some characteristics of strain SJL-JDg mice
    • CRISPENS, C. G., 1973 Some characteristics of strain SJL-JDg mice. Lab. Anim. Sci. 23: 408-413.
    • (1973) Lab. Anim. Sci. , vol.23 , pp. 408-413
    • Crispens, C.G.1
  • 9
    • 0027359459 scopus 로고
    • Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer
    • DASSONVILLE, O., J. L. FORMENTO, M. FRANCOUAL, A. RAMAIOLI, J. SANTINI et al., 1993 Expression of epidermal growth factor receptor and survival in upper aerodigestive tract cancer. J. Clin. Oncol. 11: 1873-1878.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 1873-1878
    • Dassonville, O.1    Formento, J.L.2    Francoual, M.3    Ramaioli, A.4    Santini, J.5
  • 10
    • 0029852580 scopus 로고    scopus 로고
    • Use of a cDNA microarray to analyse gene expression patterns in human cancer
    • DERISI, J., L. PENLAND, P. O. BROWN, M. L. BITTNER, P. S. MELTZER et al., 1996 Use of a cDNA microarray to analyse gene expression patterns in human cancer. Nat. Genet. 14: 457-460.
    • (1996) Nat. Genet. , vol.14 , pp. 457-460
    • Derisi, J.1    Penland, L.2    Brown, P.O.3    Bittner, M.L.4    Meltzer, P.S.5
  • 11
    • 0030953468 scopus 로고
    • Activation of HER4 by heparin-binding -like growth factor stimulates chemotaxis but not proliferation
    • ELENIUS, K., S. PAUL, G. ALLISON, J. SUN and M. KLAGSBRUN, 1991 Activation of HER4 by heparin-binding -like growth factor stimulates chemotaxis but not proliferation. EMBO J. 16: 1268-1278.
    • (1991) EMBO J. , vol.16 , pp. 1268-1278
    • Elenius, K.1    Paul, S.2    Allison, G.3    Sun, J.4    Klagsbrun, M.5
  • 12
    • 0015979296 scopus 로고
    • Differential susceptibility of four mouse strains to induction of multiple large bowel neoplasms by 1,2-dimethylhydrazine
    • EVANS, J., T. HAUSCHKA and A. MITTELMAN, 1974 Differential susceptibility of four mouse strains to induction of multiple large bowel neoplasms by 1,2-dimethylhydrazine. J. Natl. Cancer Inst. 52: 999-1000.
    • (1974) J. Natl. Cancer Inst. , vol.52 , pp. 999-1000
    • Evans, J.1    Hauschka, T.2    Mittelman, A.3
  • 13
    • 0028266378 scopus 로고
    • Alterations of human placental epidermal growth factor receptor in intrauterine growth retardation
    • FONDACCI, C., E. ALSAT, R. GABRIEL, P. BLOT, C. NESSMANN et al., 1994 Alterations of human placental epidermal growth factor receptor in intrauterine growth retardation. J. Clin. Invest. 93: 1149-1155.
    • (1994) J. Clin. Invest. , vol.93 , pp. 1149-1155
    • Fondacci, C.1    Alsat, E.2    Gabriel, R.3    Blot, P.4    Nessmann, C.5
  • 14
    • 0028944112 scopus 로고
    • A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on the receptor biochemistry that results in impaired lactation
    • FOWLER, K. J., F. WALKER, W. ALEXANDER, M. L. HIBBS, E. C. NICE et al., 1995 A mutation in the epidermal growth factor receptor in waved-2 mice has a profound effect on the receptor biochemistry that results in impaired lactation. Proc. Natl. Acad. Sci. USA 92: 1465-1469.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 1465-1469
    • Fowler, K.J.1    Walker, F.2    Alexander, W.3    Hibbs, M.L.4    Nice, E.C.5
  • 15
    • 0032478998 scopus 로고    scopus 로고
    • Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival
    • GRANDIS, J. R., M. F. MELHEM, W. E. GOODING, R. DAY, V. A. HOLST et al., 1998 Levels of TGF-alpha and EGFR protein in head and neck squamous cell carcinoma and patient survival. J. Natl. Cancer Inst. 90: 824-832.
    • (1998) J. Natl. Cancer Inst. , vol.90 , pp. 824-832
    • Grandis, J.R.1    Melhem, M.F.2    Gooding, W.E.3    Day, R.4    Holst, V.A.5
  • 16
    • 0033032004 scopus 로고    scopus 로고
    • MHC characterization of ALR and ALS mice: Respective similarities to the NOD and NON strains
    • GRASER, R. T., C. E. MATHEWS, E. H. LEITER and D. V. SERREZE, 1999 MHC characterization of ALR and ALS mice: respective similarities to the NOD and NON strains. Immunogenetics 49: 722-726.
    • (1999) Immunogenetics , vol.49 , pp. 722-726
    • Graser, R.T.1    Mathews, C.E.2    Leiter, E.H.3    Serreze, D.V.4
  • 17
    • 0038718522 scopus 로고    scopus 로고
    • Developing inhibitors of the epidermal growth factor receptor for cancer treatment
    • GRUNWALD, V., and M. HIDALGO, 2003 Developing inhibitors of the epidermal growth factor receptor for cancer treatment. J. Natl. Cancer Inst. 95: 851-867.
    • (2003) J. Natl. Cancer Inst. , vol.95 , pp. 851-867
    • Grunwald, V.1    Hidalgo, M.2
  • 18
    • 0031600881 scopus 로고    scopus 로고
    • Type I growth factor receptors: Current status and future work
    • GULLICK, W. J., 1998 Type I growth factor receptors: current status and future work. Biochem. Soc. Symp. 63: 193-198.
    • (1998) Biochem. Soc. Symp. , vol.63 , pp. 193-198
    • Gullick, W.J.1
  • 19
    • 0002909671 scopus 로고
    • Genetics of neoplasia
    • edited by W. J. Burdette. Holden-Day, San Francisco
    • HESTON, W. E., 1963 Genetics of neoplasia, pp. 247-268 in Methodology in Mammalian Genetics, edited by W. J. BURDETTE. Holden-Day, San Francisco.
    • (1963) Methodology in Mammalian Genetics , pp. 247-268
    • Heston, W.E.1
  • 20
    • 0025904265 scopus 로고
    • A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF
    • HIGASHIYAMA, S., J. A. ABRAHAM, J. MILLER, J. C. FIDDES and M. KLAGSBRUN, 1991 A heparin-binding growth factor secreted by macrophage-like cells that is related to EGF. Science 251: 936-939.
    • (1991) Science , vol.251 , pp. 936-939
    • Higashiyama, S.1    Abraham, J.A.2    Miller, J.3    Fiddes, J.C.4    Klagsbrun, M.5
  • 21
    • 0035400051 scopus 로고    scopus 로고
    • Genetical genomics: The added value from segregation
    • JANSEN, R. C., and J. P. NAP, 2001 Genetical genomics: the added value from segregation. Trends Genet. 17: 388-391.
    • (2001) Trends Genet. , vol.17 , pp. 388-391
    • Jansen, R.C.1    Nap, J.P.2
  • 22
    • 0031823493 scopus 로고    scopus 로고
    • NIDDM genes in mice: Deleterious synergism by both parental genomes contributes to diabetogenic thresholds
    • LEITER, E. H., P. C. REIFSNYDER, K. FLURKEY, H. J. PARTKE, E. JUNGER et al., 1998 NIDDM genes in mice: deleterious synergism by both parental genomes contributes to diabetogenic thresholds. Diabetes 47: 1287-1295.
    • (1998) Diabetes , vol.47 , pp. 1287-1295
    • Leiter, E.H.1    Reifsnyder, P.C.2    Flurkey, K.3    Partke, H.J.4    Junger, E.5
  • 23
    • 0028344729 scopus 로고
    • The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase
    • LUETTEKE, N. C., H. K. PHILLIPS, T. H. QIU, N. G. COPELAND, H. S. EARP et al., 1994 The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase. Genes Dev. 8: 399-413.
    • (1994) Genes Dev. , vol.8 , pp. 399-413
    • Luetteke, N.C.1    Phillips, H.K.2    Qiu, T.H.3    Copeland, N.G.4    Earp, H.S.5
  • 24
    • 0021360015 scopus 로고
    • Rat transforming growth factor type I: Structure and relation to epidermal growth factor
    • MARQUARDT, H., M. M. HUNKAPILLER, L. E. HOOD and G. J. TODARO, 1984 Rat transforming growth factor type I: structure and relation to epidermal growth factor. Science 223: 1079-1082.
    • (1984) Science , vol.223 , pp. 1079-1082
    • Marquardt, H.1    Hunkapiller, M.M.2    Hood, L.E.3    Todaro, G.J.4
  • 25
    • 0041629450 scopus 로고    scopus 로고
    • Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer
    • MENDELSOHN, J., and J. BASELGA, 2003 Status of epidermal growth factor receptor antagonists in the biology and treatment of cancer. J. Clin. Oncol. 21: 2787-2799.
    • (2003) J. Clin. Oncol. , vol.21 , pp. 2787-2799
    • Mendelsohn, J.1    Baselga, J.2
  • 26
    • 0029074587 scopus 로고
    • Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor
    • MIETTINEN, P. J., J. E. BERGER, J. MENESES, Y. PHUNG, R. A. PEDERSEN et al., 1995 Epithelial immaturity and multiorgan failure in mice lacking epidermal growth factor receptor. Nature 376: 337-341.
    • (1995) Nature , vol.376 , pp. 337-341
    • Miettinen, P.J.1    Berger, J.E.2    Meneses, J.3    Phung, Y.4    Pedersen, R.A.5
  • 27
    • 13044304179 scopus 로고    scopus 로고
    • Distinctive gene expression patterns in human mammary epithelial cells and breast cancers
    • PEROU, C. M., S. S. JEFFREY, M. VAN DE RIJN, C. A. REES, M. B. EISEN et al., 1999 Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc. Natl. Acad. Sci. USA 96: 9212-9217.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 9212-9217
    • Perou, C.M.1    Jeffrey, S.S.2    Van De Rijn, M.3    Rees, C.A.4    Eisen, M.B.5
  • 28
    • 0035884608 scopus 로고    scopus 로고
    • Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis
    • RICKMAN, D. S., M. P. BOBEK, D. E. MISEK, R. KUICK, M. BLAIVAS et al., 2001 Distinctive molecular profiles of high-grade and low-grade gliomas based on oligonucleotide microarray analysis. Cancer Res. 61: 6885-6891.
    • (2001) Cancer Res. , vol.61 , pp. 6885-6891
    • Rickman, D.S.1    Bobek, M.P.2    Misek, D.E.3    Kuick, R.4    Blaivas, M.5
  • 29
    • 0030027165 scopus 로고    scopus 로고
    • Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor receptor or neuregulin-β
    • RIESE, D. J., Y. BERMINGHAM, T. M. VAN RAAIJ, S. BUCKLEY, G. D. PLOWMAN et al., 1996 Betacellulin activates the epidermal growth factor receptor and erbB-4, and induces cellular response patterns distinct from those stimulated by epidermal growth factor receptor or neuregulin-β. Oncogene 12: 345-353.
    • (1996) Oncogene , vol.12 , pp. 345-353
    • Riese, D.J.1    Bermingham, Y.2    Van Raaij, T.M.3    Buckley, S.4    Plowman, G.D.5
  • 30
    • 0032080266 scopus 로고    scopus 로고
    • Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2
    • RIESE, D. J., T. KOMURASAKI, G. D. PLOWMAN and D. F. STERN, 1998 Activation of ErbB4 by the bifunctional epidermal growth factor family hormone epiregulin is regulated by ErbB2. J. Biol. Chem. 273: 11288-11294.
    • (1998) J. Biol. Chem. , vol.273 , pp. 11288-11294
    • Riese, D.J.1    Komurasaki, T.2    Plowman, G.D.3    Stern, D.F.4
  • 31
    • 0027159063 scopus 로고
    • Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung
    • RUSCH, V., J. BASELGA, C. CORDON-CARDO, J. ORAZEM, M. ZAMAN et al., 1993 Differential expression of the epidermal growth factor receptor and its ligands in primary non-small cell lung cancers and adjacent benign lung. Cancer Res. 53: 2379-2385.
    • (1993) Cancer Res. , vol.53 , pp. 2379-2385
    • Rusch, V.1    Baselga, J.2    Cordon-Cardo, C.3    Orazem, J.4    Zaman, M.5
  • 32
    • 0027400724 scopus 로고
    • Betacellulin: A novel mitogen from pancreatic β-tumor cells
    • SHING, Y., G. CHRISTOFORI, D. HANAHAN, Y. ONO, R. SASADA et al., 1993 Betacellulin: a novel mitogen from pancreatic β-tumor cells. Science 259: 1604-1607.
    • (1993) Science , vol.259 , pp. 1604-1607
    • Shing, Y.1    Christofori, G.2    Hanahan, D.3    Ono, Y.4    Sasada, R.5
  • 33
    • 0029045856 scopus 로고
    • Strain-dependent epithelial defects in mice lacking the EGF receptor
    • SIBILIA, M., and E. F. WAGNER, 1995 Strain-dependent epithelial defects in mice lacking the EGF receptor. Science 269: 234-238.
    • (1995) Science , vol.269 , pp. 234-238
    • Sibilia, M.1    Wagner, E.F.2
  • 34
    • 0035947578 scopus 로고    scopus 로고
    • Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily
    • STRACHAN, L., J. G. MURISON, R. L. PRESTIDGE, M. A. SLEEMAN, J. D. WATSON et al., 2001 Cloning and biological activity of epigen, a novel member of the epidermal growth factor superfamily. J. Biol. Chem. 276: 18265-18271.
    • (2001) J. Biol. Chem. , vol.276 , pp. 18265-18271
    • Strachan, L.1    Murison, J.G.2    Prestidge, R.L.3    Sleeman, M.A.4    Watson, J.D.5
  • 35
    • 0033846715 scopus 로고    scopus 로고
    • Biomarker conservation in primary and metastatic epithelial ovarian cancer
    • TEWARI, K. S., A. S. KYSHTOOBAYEVA, R. S. MEHTA, I. R. YU, R. A. BURGER et al., 2000 Biomarker conservation in primary and metastatic epithelial ovarian cancer. Gynecol. Oncol. 78: 130-136.
    • (2000) Gynecol. Oncol. , vol.78 , pp. 130-136
    • Tewari, K.S.1    Kyshtoobayeva, A.S.2    Mehta, R.S.3    Yu, I.R.4    Burger, R.A.5
  • 36
    • 0029064203 scopus 로고
    • Targeted disruption of mouse EGF receptor: Effect of genetic background on mutant phenotype
    • THREADGILL, D. W., A. A. DLUGOSZ, L. A. HANSEN, T. TENNENBAUM, U. LICHTI et al., 1995 Targeted disruption of mouse EGF receptor: effect of genetic background on mutant phenotype. Science 269: 230-234.
    • (1995) Science , vol.269 , pp. 230-234
    • Threadgill, D.W.1    Dlugosz, A.A.2    Hansen, L.A.3    Tennenbaum, T.4    Lichti, U.5
  • 37
    • 0028937620 scopus 로고
    • Epiregulin: A novel epidermal growth factor with mitogenic activity for rat primary hepatocytes
    • TOYODA, H., T. KOMURASAKI, D. UCHIDA, Y. TAKAYAMA, T. ISOBE et al., 1995 Epiregulin: a novel epidermal growth factor with mitogenic activity for rat primary hepatocytes. J. Biol. Chem. 270: 7495-7500.
    • (1995) J. Biol. Chem. , vol.270 , pp. 7495-7500
    • Toyoda, H.1    Komurasaki, T.2    Uchida, D.3    Takayama, Y.4    Isobe, T.5
  • 38
    • 0034693634 scopus 로고    scopus 로고
    • Co-expression of epidermal growth factor receptor and transforming growth factor-alpha predicts worse prognosis in breast-cancer patients
    • UMEKITA, Y., Y. OHI, Y. SAGARA and H. YOSHIDA, 2000 Co-expression of epidermal growth factor receptor and transforming growth factor-alpha predicts worse prognosis in breast-cancer patients. Int. J. Cancer 89: 484-487.
    • (2000) Int. J. Cancer , vol.89 , pp. 484-487
    • Umekita, Y.1    Ohi, Y.2    Sagara, Y.3    Yoshida, H.4
  • 39
    • 0037069380 scopus 로고    scopus 로고
    • Combining mapping and arraying: An approach to candidate gene identification
    • WAYNE, M. L., and L. M. MCINTYRE, 2002 Combining mapping and arraying: an approach to candidate gene identification. Proc. Natl. Acad. Sci. USA 99: 14903-14906.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 14903-14906
    • Wayne, M.L.1    Mcintyre, L.M.2
  • 40
    • 1342294092 scopus 로고    scopus 로고
    • Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation
    • YANG, Y. H., S. DUDOIT, P. LUU, D. M. LIN, V. PENG et al., 2002 Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res. 30: e15.
    • (2002) Nucleic Acids Res. , vol.30
    • Yang, Y.H.1    Dudoit, S.2    Luu, P.3    Lin, D.M.4    Peng, V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.